Igor Francisco Chagas Dos Santos, Alexandre Sampaio Moura, Matheus Marchesotti Dutra Ferraz, Carla Maria Gonçalves de Macedo Moreira, Paula Meireles, Maria das Graças Braga
{"title":"Mutations associated with viral resistance to integrase in individuals initiating dolutegravir-containing antiretroviral therapy: retrospective cohort, Brazil 2017-2019.","authors":"Igor Francisco Chagas Dos Santos, Alexandre Sampaio Moura, Matheus Marchesotti Dutra Ferraz, Carla Maria Gonçalves de Macedo Moreira, Paula Meireles, Maria das Graças Braga","doi":"10.1080/09540121.2025.2474672","DOIUrl":"https://doi.org/10.1080/09540121.2025.2474672","url":null,"abstract":"<p><p>Retrospective cohort aimed to analyze viral resistance mutations to integrase in people living with HIV/Aids (PLWHA) in Brazil. Patients receiving first-line therapy with a three-drug antiretroviral (ART) regimen containing dolutegravir (DTG), with HIV-1 genotypic resistance test available after starting treatment, were included. Data from three national databases related to antiretroviral dispensing, LT CD4+ cell count and HIV viral load (VL), and genotyping resistance testing were linked. Ideal adherence was defined as the proportion of days covered (PDC) ≥ 80%. Thirty (7.0%) of the 430 participants had resistance to DTG; five had high and 11 had moderate resistance levels. The N155H (<i>n</i> = 9) and E138K (<i>n</i> = 7) mutations were the most prevalent. DTG mutations were significantly more prevalent among males, whites, and those with HIV-VL count > 100,000 copies/mL, switching to alternative regimens or with resistance mutations to other classes of antiretroviral drugs (<i>p</i> < 0.05). Ideal ART adherence was observed in 52.8% of the participants and it was associated with DTG mutations (<i>p</i> < 0.001). This study described the resistance mutations to DTG in individuals starting treatment with this drug and the characteristics of such individuals. Understanding such a profile is crucial to regions where a DTG-containing regimen is the recommended first-line therapy.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-11"},"PeriodicalIF":1.2,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nsika Sithole, Busisiwe Nkosi, Janet Seeley, Ruanne V Barnabas, Mark J Siedner, Mosa Moshabela
{"title":"Navigating HIV care in a mobile society: case studies of clinic transfers in South Africa's public health sector.","authors":"Nsika Sithole, Busisiwe Nkosi, Janet Seeley, Ruanne V Barnabas, Mark J Siedner, Mosa Moshabela","doi":"10.1080/09540121.2025.2479044","DOIUrl":"10.1080/09540121.2025.2479044","url":null,"abstract":"<p><p>In South Africa, people living with HIV (PWH) often relocate for work and family obligations, which creates unique challenges for continuous HIV care. We explored the experiences of mobile individuals living with HIV navigating clinic transfers without formal letters. A qualitative study was conducted with PWH on antiretroviral therapy (ART) from two clinics in KwaZulu-Natal. Participants, who had not disclosed their HIV treatment history at registration, were interviewed in-depth between March and October 2023. Content and thematic analyses, informed by Andersen's behavioral model and self-management domains, were used. This study presents two case studies of individuals who faced challenges with accessing ART after relocating to new areas: a 37-year-old female worker and a 47-year-old male construction worker. Both faced difficulties accessing ART after relocation. When they presented at new clinics, they were told they could not access care without transfer letters. Unable to return to previous clinics, they sought treatment at a third clinic as treatment-naive, changing their names to avoid detection. To cover ART gaps, they also purchased or borrowed ART from others. These individuals developed strategies to overcome barriers. Educating clinic staff on the challenges faced by migrants could help improve transfers.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Audrey Hang Hai, David Scott Batey, Christina S Lee, Jocelyn N Simons, Anna Beadleston, Rebecca Schnall
{"title":"Substance use patterns among U.S. adults with HIV: identifying priorities for screening and interventions.","authors":"Audrey Hang Hai, David Scott Batey, Christina S Lee, Jocelyn N Simons, Anna Beadleston, Rebecca Schnall","doi":"10.1080/09540121.2025.2477718","DOIUrl":"https://doi.org/10.1080/09540121.2025.2477718","url":null,"abstract":"<p><p>Given the significant syndemic of HIV and substance use in the U.S., this study sought to examine substance use patterns (consistent user, former user, recent adopter, and abstainers) and identify sociodemographic disparities among people with HIV (PWH). Using 2015-2019 National Survey on Drug Use and Health data (<i>N</i> = 212,411), we estimated prevalence rates and conducted multinomial logistic regression to assess associations between HIV status and (1) substance use and (2) sociodemographic factors. Results show PWH have higher rates of consistent and former use of a range of substances, including inhalants, methamphetamine, cocaine, and heroin. Younger PWH are more likely to use cannabis and hallucinogens, while middle-aged PWH show elevated methamphetamine use. Male and urban-residing PWH face higher risks for inhalants and cocaine. These findings underscore the need for targeted interventions addressing substance use disparities among PWH, particularly for high-risk subgroups and substances. Integrated care models emphasizing harm reduction and relapse prevention are critical. Policy reforms should expand Medicaid and Ryan White Program coverage to include comprehensive substance use treatment for PWH. Future research should explore longitudinal patterns of substance use transitions and the impact of structural factors such as stigma on these disparities to inform effective prevention and treatment strategies.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-12"},"PeriodicalIF":1.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cassandra Fairhead, Tristan J Barber, Hajra Okhai, Russell Durkin, Jennifer Hart, Jessica Pinto, Alan Hunter, Douglas Macdonald, Fiona Burns
{"title":"Demographic disparities in blood-borne-virus screening in two London Emergency Departments: a case for implied consent.","authors":"Cassandra Fairhead, Tristan J Barber, Hajra Okhai, Russell Durkin, Jennifer Hart, Jessica Pinto, Alan Hunter, Douglas Macdonald, Fiona Burns","doi":"10.1080/09540121.2025.2477721","DOIUrl":"https://doi.org/10.1080/09540121.2025.2477721","url":null,"abstract":"<p><p>\"Opt-out\" Emergency Department (ED) blood-borne-virus screening enables early diagnosis, improving outcomes. Whereas some EDs encourage verbal reminders at blood draw, others emphasise \"implied consent\". Associations between these approaches and screening equity have not been explored. This retrospective cohort evaluation quantified demographic disparities in screening in two EDs following \"reminder model\" screening rollout. Staff attitudes were explored, identifying screening barriers. ED attendees from July-October 2022 were identified electronically. Associations between age, sex, self-identified ethnicity, attendance time and admission status on screening were analysed using odds ratios (ORs). Twenty ED staff underwent semi-structured interviews. There were 33,388 eligible ED attendances (54.8% female; median age 53y). 58.9% of attendees received screening. In unadjusted analysis, the screening rate was higher in men (OR 1.05; 95%CI 1.00-1.10) and in non-admitted attendees. People of Black, Asian or Other ethnic backgrounds had lower rates compared to White ethnicity. Attendees between 5pm-11pm had lower rates and 11pm-9am higher rates compared to 9am-5pm. All associations persisted in multivariable models. Interviews revealed low confidence in follow-up discussion in attendees who opted out and a high workload precluding screening. Demographic disparities were seen in this \"reminder model\" context. Simplifying processes and emphasising implied consent may improve equitable screening.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pamela Valera, Tajrian Amad, Jamie Delaney, Joachim Sackey, Daina Potter, Karin Palomino, Rida Sohail, Teri Lassiter
{"title":"Using global positioning systems to explore food insecurity among older adults living with HIV, with and without criminal justice involvement.","authors":"Pamela Valera, Tajrian Amad, Jamie Delaney, Joachim Sackey, Daina Potter, Karin Palomino, Rida Sohail, Teri Lassiter","doi":"10.1080/09540121.2025.2476639","DOIUrl":"https://doi.org/10.1080/09540121.2025.2476639","url":null,"abstract":"<p><p>This study assessed the feasibility and acceptability of using global positioning systems (GPS) to evaluate food insecurity among older people living with HIV (PLWH), including those with criminal justice involvement. Approximately 25 PLWH participants were recruited via community engagement from September 2023 to January 2024. Bivariate analyses identified demographic characteristics, and chi-square tests investigated the association between arrest/incarceration history and food security. Spatial analysis examined patterns, calculated distances traveled and determined the frequency of visits to specific locations over seven days. Around 20.8% (<i>n</i> = 5) of participants had a CD4 count of ≤299 cells/mm³, indicating possible advanced HIV status. Food insecurity was higher among participants with lower education levels (61.5%; <i>n</i> = 8) and incomes ≤$20,000 annually (69.2%; <i>n</i> = 9). Those with arrest histories had slightly higher food insecurity rates (54.5%; <i>n</i> = 6) compared to those never arrested (45.5%; <i>n</i> = 5), though differences were not statistically significant. Most participants successfully charged and carried their GPS devices and retained food receipts. GPS compliance was higher at the start and middle of the study period but declined toward the end. Findings support that integrating geospatial technology is both feasible and acceptable for assessing food insecurity among older PLWH.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-13"},"PeriodicalIF":1.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Zapata Vaca, Chermiqua Rachelle Tsosie, Erin Logue-Chamberlain, Paulina Coutifaris, Theresa Christensen, Alexandria Bea Mabry, Ola Mohamed, Ellen Tedaldi, Emily A Oliver, William R Short, Elizabeth D Lowenthal
{"title":"\"My body my baby\": a qualitative study examining drivers of infant-feeding choices among women living with HIV in Philadelphia, United States.","authors":"Martina Zapata Vaca, Chermiqua Rachelle Tsosie, Erin Logue-Chamberlain, Paulina Coutifaris, Theresa Christensen, Alexandria Bea Mabry, Ola Mohamed, Ellen Tedaldi, Emily A Oliver, William R Short, Elizabeth D Lowenthal","doi":"10.1080/09540121.2025.2474666","DOIUrl":"https://doi.org/10.1080/09540121.2025.2474666","url":null,"abstract":"<p><p>Before national guidelines related to infant feeding among people living with HIV (PLHIV) in the United States were changed in 2023, PLHIV were discouraged from breastfeeding due to the potential risk of perinatal HIV transmission. Potential health benefits to both mother and child coupled with the ability to mitigate HIV transmission risk with modern treatments now make feeding decisions more complex for PLHIV. This study examined personal and social determinants of feeding choice among PLHIV in the Philadelphia area just prior to the change in national guidelines. In 2022 and 2023, we conducted in-depth interviews with 28 PLHIV between the ages of 18-50 years old that had previously given birth, 22 while living with HIV. Participants who gave birth while living with HIV expressed that they had not been given the choice to breastfeed. When probed about how they would consider choice in a hypothetical future pregnancy in the new guidelines era, participants' own knowledge and beliefs about what was best for their babies and themselves were consistently raised as the most influential factors. They relied strongly on their health providers for up-to-date knowledge. Advice from partners, family, and community was considered less influential for most.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-13"},"PeriodicalIF":1.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Courtney Peasant Bonner, Wendee M Wechsberg, Erin Cox, Felicia A Browne, Ayanna Smith, Brittni N Howard, Noah Mancuso, Suzzanne Singer, Gwen Davies, Indya Hairston, Precious K Ukaegbu, Dazon Dixon Diallo
{"title":"\" … They cannot help you because you're at McDonald's and you're asking for pizza\". A qualitative exploration of the acceptability and appropriateness of integrating of pharmacotherapy for mental health treatment in HIV care among patients living with HIV and co-morbid mental health and substance use disorders.","authors":"Courtney Peasant Bonner, Wendee M Wechsberg, Erin Cox, Felicia A Browne, Ayanna Smith, Brittni N Howard, Noah Mancuso, Suzzanne Singer, Gwen Davies, Indya Hairston, Precious K Ukaegbu, Dazon Dixon Diallo","doi":"10.1080/09540121.2025.2474670","DOIUrl":"https://doi.org/10.1080/09540121.2025.2474670","url":null,"abstract":"<p><p>Mental health disorders contribute to a lack of HIV care retention and adherence. Pharmacotherapy for mental health treatment may increase retention and adherence. However, there is often a lack of pharmacotherapy services for mental health treatment available in HIV care. The current study explores the extent to which people living with HIV find the integration of pharmacotherapy for mental health treatment into HIV care acceptable and appropriate. We conducted in-depth interviews with ten patients living with HIV and comorbid mental health or substance use challenges. We used rapid qualitative analysis to analyze the transcript data. Patients cited several barriers to mental health treatment, including having to coordinate and establish rapport with other providers. Participants' perspectives about whether HIV care providers should provide pharmacotherapy for mental health treatment varied. However, most respondents agreed that it would be beneficial for HIV care providers to maintain existing regimens or address lapses in mental health care. Patients also cited benefits to integration, including the ability to receive care from a trusted provider and increased access. These findings add to previous literature and demonstrate the nuanced nature of the acceptability of receiving pharmacotherapy for mental health treatment from an HIV care provider.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with placement along the HIV prevention and care continuum among sexual minority men who use methamphetamine.","authors":"Cathy J Reback, Chunqing Lin, Michael J Li","doi":"10.1080/09540121.2025.2473942","DOIUrl":"10.1080/09540121.2025.2473942","url":null,"abstract":"<p><p>Methamphetamine use among sexual minority men (SMM) has been associated with poor ART adherence, and reduced initiation and adherence to PrEP. From May 2021 to May 2023, 226 SMM were enrolled in <i>Getting Off</i>, a culturally responsive smartphone application to reduce methamphetamine use and improve sexual health. Using a status-neutral approach, an ordinal variable reflected participants' placement on the HIV Prevention/Care Continuum, from HIV-positive, not taking ART, to HIV-negative, currently taking PrEP. An ordinal logistic model was structured to identify factors associated with participants' placement on the Continua. Of the 99 SMM at risk of HIV, 57.6% had an HIV test within three months. The majority (<i>n</i> = 77; 77.8%) had heard of PrEP, among whom only 28 (36.4%) were currently on PrEP. Among the 127 (56.2%) participants with HIV, 61 (48.0%) had viral load testing in the last three months, and 48 (37.8%) were virally suppressed. With demographics, social determinants of health, and substance use/sexual risk behaviors controlled, those with post-graduate education were more likely to have higher placement in the Continua (OR = 2.12, <i>P</i> = 0.011). STI in the past 12 months was correlated with lesser placement (OR = 0.57; <i>P</i> = 0.045). Neither methamphetamine use disorder nor readiness to change was correlated with Continua placement.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula Knoch Mendonça Gil, Danilo Dos Santos Conrado, Ana Isabel do Nascimento, João Cesar Pereira da Cunha, Gabriel Serrano Ramires Koch, Camila Guadeluppe Maciel, Cláudia Du Bocage Santos-Pinto, Everton Falcão de Oliveira
{"title":"Knowledge and perception of HIV pre-exposure prophylaxis among healthcare workers.","authors":"Paula Knoch Mendonça Gil, Danilo Dos Santos Conrado, Ana Isabel do Nascimento, João Cesar Pereira da Cunha, Gabriel Serrano Ramires Koch, Camila Guadeluppe Maciel, Cláudia Du Bocage Santos-Pinto, Everton Falcão de Oliveira","doi":"10.1080/09540121.2025.2473940","DOIUrl":"https://doi.org/10.1080/09540121.2025.2473940","url":null,"abstract":"<p><p><b>Introduction:</b> In Brazil, pre-exposure prophylaxis (PrEP) is freely available to individuals at high risk of HIV infection. However, knowledge and perception of PrEP can act as barriers to its access and use. This study evaluated PrEP knowledge and perception among healthcare workers in the Unified Health System in a Brazilian capital. <b>Methods:</b> This cross-sectional study collected data through interviews with healthcare workers from 72 Primary Health Care (PHC) units and 5 Specialized Care (SC) services in Campo Grande, Mato Grosso do Sul. Binomial logistic regression models were used to analyze factors associated with PrEP knowledge and perception. <b>Results:</b> A total of 372 professionals were interviewed. The majority were PHC professionals (93.0%), female (76.1%), aged between 30 and 39 years (41.4%), heterosexual (83.3%), and non-white (51.9%). PrEP knowledge was higher among LGBTQIA + professionals, those with less than one year of healthcare work experience, those with a positive perception of PrEP, and those attending more patients per day. A positive perception of PrEP was significantly higher among professionals who care for people living with HIV and lower among those with limited knowledge about PrEP. <b>Discussion:</b> Identifying factors influencing PrEP access may help develop strategies to improve knowledge and perception, particularly in high-impact areas.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-10"},"PeriodicalIF":1.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ye Chen, Xiangyi Tang, Qiuyu Chen, Ying Zhang, Qinglan Xia, Qiang Wang
{"title":"Effectiveness of HIV health education interventions on the MSM population: a meta-analysis.","authors":"Ye Chen, Xiangyi Tang, Qiuyu Chen, Ying Zhang, Qinglan Xia, Qiang Wang","doi":"10.1080/09540121.2025.2474673","DOIUrl":"https://doi.org/10.1080/09540121.2025.2474673","url":null,"abstract":"<p><p>Men who have sex with men (MSM) face a heightened risk of HIV, presenting a significant public health issue. This meta-analysis evaluates the effectiveness of HIV health education for MSM by examining changes in knowledge, attitudes, and behaviors across different cultures and regions. The study also explores heterogeneity sources through subgroup and sensitivity analyses to guide future research. Searches were conducted in databases including China Knowledge, Wipo, Wanfang, PubMed, and Web of Science, covering studies up to December 1, 2023. Included were controlled pre-post trials on HIV education's impact on MSM. Independent data extraction and analysis were completed by two researchers using RevMan 5.7. Pre-registration was done with PROSPERO. Twenty-seven studies met criteria. Post-intervention, significant improvements were noted in HIV knowledge (OR: 0.49; 95% CI: 0.44-0.56), condom use over six months (OR: 0.47; 95% CI: 0.38-0.58), and condom use in recent same-sex encounters (OR: 0.44; 95% CI: 0.29-0.66). Larger samples (>500) or long-term interventions (>1 year) enhanced homogeneity (I<sup>2</sup> = 0%). In conclusion, these interventions significantly boost knowledge and condom use, identifying sample size and intervention duration as primary heterogeneity influences, guiding future strategy optimization.</p>","PeriodicalId":48370,"journal":{"name":"Aids Care-Psychological and Socio-Medical Aspects of Aids/hiv","volume":" ","pages":"1-11"},"PeriodicalIF":1.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}