Prevention Science最新文献

{"title":"Early Effects of Communities That Care on System Transformation: a Non-randomized Community Trial in Germany.","authors":"Dominik Röding, Isabell von Holt, Lea Decker, Ulla Walter","doi":"10.1007/s11121-026-01961-9","DOIUrl":"https://doi.org/10.1007/s11121-026-01961-9","url":null,"abstract":"<p><p>Community coalition approaches such as Communities That Care (CTC) are regarded as key strategies for translating prevention science into community-level improvements in youth outcomes. It was shown that CTC improves three system transformation outcomes. The present study aimed to conceptually replicate these findings in the German context under the highly unusual real-world implementation constraints imposed by the COVID-19 pandemic. A non-randomized community trial was carried out (2020-2023) in 22 a priori matched community-pairs from four German states. In an open cohort design, community key informants were surveyed at two time points. A total of 318 key informants from 18 ICs (n = 180) and 11 CCs (n = 138) were included in the open-cohort analyses. Outcomes included (1) adoption of a science-based approach to prevention (primary outcome), (2) sectorial collaboration (SC) for prevention, and (3) prevention collaboration (PC). Three-level mixed models were used to analyse changes over time. In addition to replicating the original binary comparison of intervention communities (ICs) and comparison communities (CCs), analyses were extended to account for heterogeneity in implementation progress across ICs resulting from pandemic-related implementation disruptions. At baseline, ICs showed significantly higher levels of SC than CCs (γ = 0.383, SE = 0.124, p = .003), whereas no significant baseline differences were observed for Adoption or SC. Compared with CCs, ICs showed a non-significant increase in the primary outcome (b = 0.272, SE = 2.306, p = .906) and PC (γ = 0.78, SE = 0.121, p = .523), whereas SC showed a non-significant decrease over time in ICs relative to CCs (γ = - 0.193, SE = 0.118, p = .107). Implementation progress was not significantly associated with changes in the primary outcome (b = 0.401, SE = 0.929, p = .666), SC (γ = 0.082, SE = 0.100, p = .415), or PC (γ = 0.018, SE = 0.094, p = .847). Sensitivity analyses based on panel data and non-imputed datasets yielded largely comparable findings. No significant effects on system transformation were observed. However, given the limited implementation progress under COVID-19 conditions, longer follow-up may be needed to assess whether CTC can achieve system-level change in Germany.  TRIAL REGISTRATION: This study was registered with German Clinical Trial Register: DRKS00022819 on Aug 18, 2021.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Test Strips for Detection of Fentanyl in Powders.","authors":"Jessica L Armstrong, Rebekah E Wharton","doi":"10.1007/s11121-026-01933-z","DOIUrl":"10.1007/s11121-026-01933-z","url":null,"abstract":"<p><p>Testing drug powders before consumption is a harm reduction measure that could help prevent accidental overdoses. Fentanyl test strips (FTS) are used to test for fentanyl in powders, but comprehensive, comparative data assessing commercial test strips' performance is currently unavailable. To address this gap, we analyzed drug powders using FTS from three different vendors using the manufacturer's recommended testing procedures. Each FTS was assessed for sensitivity to fentanyl, cross-reactivity with fentanyl analogs, and selectivity by testing other relevant compounds. None of the FTS was as sensitive as claimed by the manufacturer nor could they detect all fentanyl analogs tested, which were selected based on their recent prevalence. The drugs responsible for the most false positives were stimulants, hallucinogens, synthetic opioids, and the cutting agent, diphenhydramine. Overall, testing of DanceSafe FTS resulted in the highest sensitivity for fentanyl, the highest selectivity when tested with other substances (fewest false positives), and moderate cross-reactivity with analogs. Testing of BTNX FTS resulted in the highest cross-reactivity with fentanyl analogs and moderate sensitivity for fentanyl. These results provide valuable information when selecting FTS for harm reduction as well as understanding the implications of each test's results. While no FTS tested performed as marketed, they still remain valuable as drug checking or screening tools to prevent drug overdose deaths.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"927-936"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Efficacy of a Web-Based Sexual Health Promotion Program Using a Media Literacy Education Approach in a National Sample of Community College Students.","authors":"Tracy M Scull, Christina V Dodson, Janis B Kupersmidt, Reina Evans-Paulson, Kathryn N Stump, Liz C Reeder","doi":"10.1007/s11121-026-01930-2","DOIUrl":"10.1007/s11121-026-01930-2","url":null,"abstract":"<p><p>Young adults attending community college are an underserved population that is at high risk for STIs and unplanned pregnancy. A recent evaluation of a web-based, sexual health program, Media Aware, that uses a media literacy education approach, revealed positive short-term effects after 1 month on the sexual health cognitions and behaviors of community college students (ages 18-19) including a reduction in risky sexual behaviors. The purpose of the current study is to replicate and extend the findings reported in this earlier evaluation to a larger sample of community college students from across the USA in a longer-term study examining 12-month follow-up data. In a cluster randomized controlled trial, students from 23 community college campuses (N = 1139) either received the intervention (i.e., Media Aware) or were assigned to the Wait-list Control group, and the two groups were compared on their media literacy cognitions and sexual health cognitions and behaviors. Using an intent-to-treat design, results indicate that after 12 months, students who received Media Aware held healthier normative beliefs about risky sex and reported media messages to be less realistic, compared to students in the control group. There were no differences across groups in sexual health behaviors. Moderation analyses by gender and pretest scores were conducted. Findings show the efficacy of Media Aware for bringing about long-term changes in media and health cognitions. The findings also underscore the need for multi-level interventions that reduce community- and system-level barriers to engaging in sexual health behaviors. TRN: NCT04950686; Date of registration: 5/03/2021.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"890-902"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147976313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reframing Substance Misuse Prevention: a RE-AIM Analysis of Federal Infrastructure and Future Directions.","authors":"Dane Minnick, Laura Curran, Khary K Rigg","doi":"10.1007/s11121-026-01920-4","DOIUrl":"10.1007/s11121-026-01920-4","url":null,"abstract":"<p><p>Substance misuse prevention is a significant component of public health policy in the USA. Currently, federal prevention efforts rely primarily on a coalition-based framework supported through four mechanisms: (1) the Substance Use Prevention, Treatment, and Recovery Block Grant, (2) the Drug-Free Communities Program, (3) the Partnerships for Success initiative, and (4) Community Anti-Drug Coalitions of America. Using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework, this article critically analyzes the performance of this system and considers scalable alternatives. Findings indicate that while coalitions mobilize local stakeholders, the model is resource-intensive, inconsistently implemented, and limited in its capacity to achieve sustained, population-level impact. Proposed alternatives include integrating prevention science into professional education, mandating EBPP delivery in universal settings such as schools, embedding routine screening and early intervention, creating a national repository of free prevention programs, and expanding the use of digital applications and wearable technologies. Implications include restructuring federal funding priorities, embedding prevention within existing infrastructures, and advancing research on cost-effectiveness, sustainability, and equity.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"903-915"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13433629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing Alcohol and Cannabis Co-use and Related Harms Among Transgender and Gender Diverse Youth.","authors":"Stephanie M Penta, Alexandra Uhrig, Jeffrey D Wardell, Trevor A Hart, Sarah S Dermody","doi":"10.1007/s11121-026-01931-1","DOIUrl":"10.1007/s11121-026-01931-1","url":null,"abstract":"<p><p>Transgender and gender diverse (TGD) youth are at increased risk of co-using alcohol and cannabis and experiencing related harms due to gender minority stress (GMS). This study aimed to characterize alcohol and cannabis co-use and related harms among TGD youth. Forty Canadian TGD youth who drink completed a 21-day ecological momentary assessment (EMA) period where they reported their substance use, corresponding harms, and GMS and resilience experienced each day. Participants reported 180 alcohol-only days, 104 cannabis-only days, and 41 co-use days during the EMA period. The number of alcoholic drinks consumed did not differ between co-use days and alcohol-only days, but the number of substance-related harms was greater on co-use days relative to alcohol-only days. On days when youth reported relatively greater GMS, they were more likely to engage in co-use than alcohol-only use. On days when youth reported relatively greater resilience (i.e., pride, community connectedness), they were more likely to co-use than cannabis-only use. Co-use should be considered when developing substance use policy and treatments for TGD youth.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"916-926"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148102301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing Temporary Financial Assistance for Homelessness Prevention: a CFIR-Guided Study of Provider Perspectives.","authors":"Micaela Mercado, Megan Emily Chavez, Chelsea Nolan, Lara Law, Sara Shuman, Laura Noll, Kristin Ferguson, Hannah McEntarffer, Raechel Livingston, Shana Ellis, Jessie Helmes, Klim Drobnyh, Kelsie King, Robert Wickham","doi":"10.1007/s11121-026-01937-9","DOIUrl":"10.1007/s11121-026-01937-9","url":null,"abstract":"<p><p>Housing insecurity is a growing public health concern with significant implications for efforts to prevent homelessness. Temporary financial assistance (TFA) is an upstream intervention designed to prevent homelessness by addressing urgent housing needs through flexible, short-term financial support. Guided by the Consolidated Framework for Implementation Research (CFIR), this study examined providers' perspectives on implementing TFA across nine Arizona organizations and explored how these determinants may inform the selection and measurement of implementation outcomes. Thirty-six participants participated in interviews or focus groups to share their experiences implementing TFA. Using deductive thematic analysis, findings highlight key internal and external barriers such as complex eligibility criteria, administrative burdens, and limited affordable housing that may have affected the adoption, implementation, and sustainment of TFA delivery. Facilitators included provider training, cross-sector partnerships, and strong vendor relationships that improved adoption and integration of TFA across service settings. Providers used a range of implementation strategies, including reimbursement systems, promise-to-pay arrangements, and tiered intake processes, to overcome systemic barriers and promote recipients' housing stability. Although funding constraints and contextual challenges limited sustainment, providers demonstrated a strong commitment to adapting implementation approaches to meet recipient needs. This study contributes to the growing evidence based on the practical application of implementation science in homelessness prevention, offering insights into how determinants of implementation can strengthen intervention delivery in diverse settings. Findings inform policy, research, and practice aimed at optimizing implementation outcomes for homelessness prevention interventions.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"937-946"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Navigation: Iterative Development and Implementation of a Prenatal Psychosocial System of Care.","authors":"Helen M Milojevich, Debra L Best, W Benjamin Goodman, Peter D Rehder, Kenneth A Dodge","doi":"10.1007/s11121-026-01939-7","DOIUrl":"10.1007/s11121-026-01939-7","url":null,"abstract":"<p><p>We describe the iterative process of developing a universal psychosocial system of primary care across early life, called Community Navigation, and evaluate whether it can be implemented during the prenatal period with high engagement, identification of family needs, connections to community services, and family satisfaction. Community Navigation is a manualized program to improve child and family outcomes by engaging families during pregnancy, co-identifying their family-specific needs, and connecting them with community resources to address their needs. Continuous quality improvement efforts enhanced and refined the program leading to three iterative versions (Navigation 1.0, 2.0, and 2.1). Here, we report implementation metrics across all three versions. In each version, families were recruited during pregnancy and offered 1-3 visits with a trained Navigator. Findings from Versions 1.0 and 2.0 were used to improve the Navigation protocol, resulting in Navigation 2.1. Of the 194 Navigation 2.1 families who were eligible and offered the program, 81% completed the initial Navigation visit and 82% of those families completed at least one follow-up visit prior to birth (net total completion = 65% of the eligible population). Adherence to the protocol was 93%. Nearly all families (98%) reported at least one unmet need, with 75% reporting a major need requiring a community resource connection. Connection rates were high: 66% of families who received referrals were successfully connected to at least one community agency. Families reported high satisfaction with the program. Community Navigation holds promise as a novel system of universal primary psychosocial care for birthing families.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"971-982"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13360660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148333799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost Analysis of BEST in CLASS-Elementary: Average Cost per Teacher-Student Dyad and Marginal Cost per Additional Student.","authors":"K S Sutherland, M A Conroy, A Blandin, K L Granger, Isabel Li","doi":"10.1007/s11121-026-01938-8","DOIUrl":"10.1007/s11121-026-01938-8","url":null,"abstract":"<p><p>This study used the Ingredients Cost Method (Levin & McEwan, 2001) to calculate the average cost of implementing BEST in CLASS-Elementary, a Tier 2 program that trains and coaches teachers to provide support to focal students who have unwanted problem behavior. Data were used from kindergarten to third-grade classrooms in a multisite randomized controlled trial. We describe the average cost of implementing BEST in CLASS-Elementary per teacher-student dyad as well as the marginal cost of adding up to two additional students in classrooms receiving the training and coaching. Data from 136 teacher student dyads (N = 63 teachers) were used in the current study. The average cost to implement the program, including teacher recruitment costs, was $2,866 per teacher-student dyad in a classroom, and the marginal cost of adding an additional focal student per treated classroom was $101. The actual intervention accounted for less than half of the total costs and coaches accounted for the highest investment (almost half of the total costs). Limitations of the current study as well as implications for future research in this area are discussed.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"947-957"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13433375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148165137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of the Parent Support Program: a Randomized Controlled Trial of an Online Intervention to Increase Parental Support Among Parents and Caregivers of Trans and Nonbinary Youth.","authors":"Em Matsuno, Matt L Miller, Ga Tin Finneas Wong, Danny Shultz, Jenna Rudo-Stern, Alex E Colson, Cady Berkel","doi":"10.1007/s11121-026-01921-3","DOIUrl":"10.1007/s11121-026-01921-3","url":null,"abstract":"<p><p>The increasingly hostile sociopolitical climate is heightening psychological distress among trans and nonbinary (TNB) youth, who already face elevated risks for depression, anxiety, suicidal ideation, and substance use. Parental support is a key protective factor for TNB youth to prevent these negative mental health outcomes. Yet, there are minimal existing evidence-based interventions that aim to increase parental support among parents and caregivers (PCs) of TNB youth. The Parent Support Program (PSP) is a theory-driven, asynchronous, online intervention that was developed and refined based on community and expert feedback. This study used a randomized controlled trial (RCT) with 619 PCs of TNB youth to test the effectiveness of the PSP. We applied linear regression models with multiple imputation adjustments and propensity weights to estimate the effects of being assigned to the intervention condition (intent to treat effects) and global dosage of the PSP (total number of activities completed). Results from our intent to treat (ITT) analyses found that the PSP was effective at increasing self-compassion and PCs' self-rated level of knowledge about gender diversity. However, global dosage predicted self-rated knowledge and the use of affirming language, but not self-compassion. The PSP is a promising intervention that may be a useful resource for some PCs of TNB youth. We address limitations of the PSP and future directions of how the PSP could be further refined and tested to optimize the intervention's effectiveness and implementation, as well as clinical implications.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"859-875"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147976469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvements in Capacity Among Community Coalitions Receiving Technical Assistance Through the Coalition Check-Up.","authors":"Yvonne Gaddy, Sarah M Chilenski, Rebecca Wells, Louis D Brown","doi":"10.1007/s11121-026-01941-z","DOIUrl":"10.1007/s11121-026-01941-z","url":null,"abstract":"<p><p>Community coalitions are central to the prevention delivery system, yet their ability to implement and sustain effective strategies often depends on technical assistance (TA). TA typically strengthens coalition capacity, but many coalitions lack connection to TA, and it is costly to sustain. Low intensity TA models that support coalition capacity exist but have not been rigorously evaluated. This study examines the Coalition Check-Up (CoCU) as a low intensity TA model to strengthen coalition capacity. Using up to 3 years of data, we tested whether capacities selected by coalitions during each CoCU implementation year improved over time. Thirty-two coalitions in Pennsylvania and Missouri received TA to review their summary report on data collected yearly over 3 years and a follow-up after year 3. Each year, coalitions used their report to prioritize a capacity for action planning following the CoCU TA model. Analyses examined data from multiple baselines (i.e., before action planning at year 1, year 2, and year 3) and subsequent data collection timepoints to test for longitudinal change on prioritized capacities. Coalitions receiving TA through the CoCU model demonstrated measurable improvements over time. Capacities prioritized in year 1 significantly improved across the following years measured (β = 0.13, 95% confidence interval (CI) [0.004, 0.26]; p = .04), as did capacities selected in the second year (β = 0.20, CI [0.02, 0.37]; p = .03) and the third year (β = 0.61, CI [0.16, 1.07]; p = .01). Findings suggest that a low intensity TA model like CoCU has the potential to guide coalitions toward strategic capacity development, ultimately enhancing their ability to deliver impactful prevention initiatives.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"958-970"},"PeriodicalIF":2.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13433725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}