Prevention Science最新文献

{"title":"What Do We Know About the Stop Now and Plan Program? A Systematic Review and Meta-Analysis of an Early Invention for Children and Youth with Conduct Problems.","authors":"Stephanie G Craig, Katelyn Frankiewicz, Natalie R Stearns, Julie Girard-Lapointe, Allana Cortese, Natasha Vogel, Debra J Pepler","doi":"10.1007/s11121-025-01788-w","DOIUrl":"10.1007/s11121-025-01788-w","url":null,"abstract":"<p><p>Children who engage in aggressive behaviors are at heightened risk of being involved in the justice system, committing serious offenses, and becoming chronic offenders. The Stop Now And Plan (SNAP) program was designed as an early intervention to address several mechanisms underlying the development of conduct problems, including emotion regulation, prosocial behaviors, and parent-child relationships. The purpose of this study was to systematically review and synthesize current research on the SNAP program and conduct a meta-analysis. Following PRISMA guidelines, PubMed and PyscINFO were searched, and the developers of SNAP were contacted to ensure no articles were missed. Twenty-two peer-reviewed articles were ultimately included following a two-stage screening process. The meta-analysis revealed a moderate effect size change (SMD =  - 0.54, 95% CI [- .42, - .65], p < .001) in externalizing problems from pre- to post-SNAP Group. The narrative review found evidence for decreases in symptoms (e.g., conduct problems, aggression, delinquency, internalizing problems) across SNAP programming. There was also preliminary evidence for changes in proposed mechanisms across the groups (e.g., emotion regulation, parent behaviors, child-parent relationship). Two randomized controlled trials (RCT) supported the efficacy of the SNAP Boys Group over another active treatment. One waitlist control found similar results for the SNAP Girls Group. There is growing evidence for SNAP, attributable to the effective clinical research partnerships established by the developers. More rigorous methods and RCTs will help solidify SNAP as a top evidence-based intervention.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"644-666"},"PeriodicalIF":2.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of Stress Physiology While Parenting: a Randomized Micro-trial of Loving-Kindness Meditation on Parenting and Salivary Alpha Amylase.","authors":"Emily B Reilly","doi":"10.1007/s11121-025-01795-x","DOIUrl":"10.1007/s11121-025-01795-x","url":null,"abstract":"<p><p>Sensitive parenting early in life sets children up for healthy development, and this type of parenting draws on the parent's compassion and physiological regulation. Loving-kindness meditations (LKM) increase compassion and reduce physiological responses to stressors and so may support sensitive parenting. The current study tested the effects of a LKM on parent sensitivity and salivary alpha amylase (sAA) during a parent-child interaction. One hundred and thirty-six parents (114 mothers, 22 fathers) of toddlers (18-36 months, M = 28.85 months, SD = 5.13) participated in an online survey and were randomly assigned to listen to either a LKM, focused-imagery audio, or podcast during a video call before engaging in a play-based interaction with their toddler. Parent sAA was collected from parents at five points throughout the video call. LKM did not significantly increase parent sensitivity (B = 0.06, p = 0.86); however, there was limited variability in sensitivity in this sample (M = 6.01, SD = 0.89). The LKM did affect sAA activity (B =  - 0.66, p < 0.05) such that parents in the LKM group gradually decreased sympathetic activity across the research session, whereas the podcast group increased sAA levels after the parent-child interaction. Overall, these findings suggest that engaging in compassion and self-compassion can change the pattern of stress physiology in parents of toddlers while parenting.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"391-403"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining How Dosage of Intervention Components from the Sacramento Neighborhood Alcohol Prevention Project Affect Child Abuse and Neglect.","authors":"Bridget Freisthler, Yun Ye, Jennifer Price Wolf","doi":"10.1007/s11121-025-01804-z","DOIUrl":"https://doi.org/10.1007/s11121-025-01804-z","url":null,"abstract":"<p><p>Alcohol environmental intervention efforts have shown mixed results in reducing child abuse and neglect. In this study, we examine how the dosage of specific intervention components of the Sacramento Neighborhood Alcohol Prevention Project (SNAPP) may differentially affect child abuse outcomes. SNAPP used a quasi-experimental phased intervention design to reduce alcohol-related problems among 15-29-year-olds in two economically, racially, and ethnically diverse neighborhoods in Sacramento, California. Study activities were conducted from 1999 through 2003. The intervention occurred in 37 Census block groups (21 block groups in the South and 16 in the North) compared to 289 block groups in the At-Large comparison area. Our child abuse outcomes include substantiations of child abuse and neglect and total and alcohol-related foster care entries. Data on child abuse outcomes were obtained from the Sacramento County Department of Children and Family Services and analyzed using conditionally autoregressive spatio-temporal Bayesian analyses. Enforcement of intoxicated patron and on-premise alcohol outlet compliance checks were related to large reductions in all three outcomes in the North intervention area, 33.4% for substantiations, 44.8% for total foster care entries, and 68.4% for alcohol-related foster care entries. However, these activities were not implemented in the South area. Community awareness activities appear to increase total and alcohol-related foster care entries in the South, but reduce substantiations and total foster care entries in the North. Compliance of on-premise outlets may be an effective intervention component to reduce child abuse and neglect; however, these results need replication. Further, despite the dosage of intervention components that reduced substantiations, the overall effect of the SNAPP intervention did not reduce this outcome.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":"26 3","pages":"331-342"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community Coalition Functioning, Collaborative Structure, and Coalition Models: Enhancing Support for Evidence-Based Practice Implementation.","authors":"Youngjo Im, Louis D Brown, Rebecca Wells, M Yvonne Gaddy, Sarah M Chilenski","doi":"10.1007/s11121-025-01800-3","DOIUrl":"10.1007/s11121-025-01800-3","url":null,"abstract":"<p><p>Coalition initiatives that use evidence-based practices (EBPs) have been shown to reduce youth substance use. Despite the importance of promoting community coalitions' EBP use, there is little empirical evidence about how to do so. This study aimed to identify distinct coalition profiles that foster EBP use by examining clusters of coalitions characteristics and the type of coalition model followed. We analyzed data from 67 coalitions participating in the Coalition Check-Up, a cluster randomized trial designed to increase community anti-drug coalition capacity. Using k-means clustering approach, we identified subgroups of coalitions based on two domains of coalition capacity-functioning and collaborative structure, each also considering coalition model type. We then examined, using analysis of variance (ANOVA), the degree to which each subgroup of coalitions used EBPs. We found that (a) coalitions with higher levels of functioning characterized by sustainability, science-based approaches to prevention, community knowledge, and efficiency, using explicit theory-based models were associated with higher use of EBPs, (b) coalitions with lower levels of collaborative structure defined by formalized procedures, decentralization, sectoral diversity, and intersectoral communication, using explicit theory-based models were associated with higher EBP use, and (c) low functioning coalitions using no model were associated with the lowest level of EBP use. Characterizing coalitions' functioning, collaborative structure, and models used may help coalition leaders and technical assistance providers enhance coalition capacity that enables the use of EBPs. Findings also indicated the importance of using explicit theory-based models to increase coalition impact.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"426-437"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of Maternal Smoking During Pregnancy and Genetic Susceptibility with Incident Asthma from a Cohort Study.","authors":"Shuo Zhang, Ting Wang, Ping Zeng","doi":"10.1007/s11121-025-01793-z","DOIUrl":"10.1007/s11121-025-01793-z","url":null,"abstract":"<p><p>Maternal smoking during pregnancy exhibited an adverse influence on asthma, but its joint effect with genetic factors remained elusive. Moreover, whether there existed a moderating role of genetic susceptibility in this effect on childhood/adolescent-onset asthma (COA) and adult-out asthma (AOA) was unknown. We employed the UK Biobank cohort to estimate the effect of maternal smoking during pregnancy on the risk of offspring asthma (41,828 AOA and 15,120 COA). We investigated genetic influence on asthma and assessed the moderating role of genetic susceptibility in this effect by incorporating polygenetic risk score (PRS) and performing a stratified analysis in distinct genetic risk populations. Hazard ratio (HR) and 95% confidence intervals (CIs) were reported. We found that participants whose mother smoked during pregnancy were more likely to occur asthma (HR = 1.14, 95%CIs 1.12 ~ 1.16), with similar effects for AOA and COA. Additionally, we observed a significant association between genetic factors and asthma (HR = 1.70, 95%CIs 1.66 ~ 1.74), with a higher genetic influence on COA (HR = 2.16, 95%CIs 2.09 ~ 2.23) compared to AOA (HR = 1.84, 95%CIs 1.76 ~ 1.93). Furthermore, we revealed that genetic factors could modify the effect of maternal smoking during pregnancy on asthma especially among childhood and adolescents, with participants having high genetic risk versus low genetic risk (HR = 1.13 vs. 1.02, P = 0.035). We provided supportive evidence that maternal smoking during pregnancy and the genetic factors increased the risk of offspring asthma in whole population. We further revealed that genetic susceptibility exerted more pronounced influence on COA compared to AOA, and played a moderating role in this effect.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"343-354"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a Predictive Risk Model to Prioritize Families for Prevention Services: The Hello Baby Program in Allegheny County, PA.","authors":"Rhema Vaithianathan, Diana Benavides-Prado, Rebecca Rebbe, Emily Putnam-Hornstein","doi":"10.1007/s11121-025-01802-1","DOIUrl":"https://doi.org/10.1007/s11121-025-01802-1","url":null,"abstract":"<p><p>Population-based efforts to prevent child abuse and neglect are challenging because annual incidence rates are relatively low. Even among families that meet eligibility and risk criteria for intensive home-visiting programs, the baseline rate of maltreatment tends to be low because we use simple criteria. This creates both service (i.e., cost) and evaluation (i.e., power) challenges because a large number of families need to receive the preventive intervention to produce detectable changes in subsequent maltreatment. The increase in the availability of administrative data has made it possible to use predictive risk models (PRMs) to risk-stratify whole birth cohorts and identify children at the highest risk of maltreatment and other early childhood adversities. The current paper describes the development and validation of a PRM implemented in Allegheny County, Pennsylvania, to stratify families and newborn infants into three levels of prioritized services based on the predicted risk of child removal due to maltreatment by age 3. Using a research dataset of anonymized records for children born in Allegheny County between 2012 and 2015, predictive features were coded using data available in the county's administrative data systems. This spine was linked to child removal outcomes between 2012 and 2018, so we had a 3-year follow-up for each child. A PRM was trained to predict removals in the first 3 years of life using the least absolute shrinkage and selection operator. Predictive accuracy was measured for the highest 5% of risk scores in a holdout dataset. The model was validated using nontraining outcomes such as maternal mortality, infant mortality, and maltreatment-related fatalities and near-fatalities. The model achieved an area under the receiver operating characteristic curve of .93 (95% CI [0.92, 0.95]), recall of 19.93%, and precision of 54.10%. Children identified for the top tier of services had a relative risk ratio of maltreatment-related fatality or near-fatality of 5.54 (95% CI [3.41, 9.00]). Using alternative eligibility approaches (e.g., poverty, teen maternal age) proved far inferior to using PRM in targeting services for children at high baseline risk of maltreatment.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":"26 3","pages":"321-330"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Suicidal Thoughts and Behaviors Among LGBTQ + Youth: Differential Associations Between Bullying and Substance Use.","authors":"Cayson W Tiedge, Alberto Valido, Matthew Rivas-Koehl, Brian A Garcia, Luz E Robinson, Graceson Clements, Dorothy L Espelage","doi":"10.1007/s11121-025-01783-1","DOIUrl":"10.1007/s11121-025-01783-1","url":null,"abstract":"<p><p>Rates of suicidal thoughts and behaviors (STB, i.e., suicidal thoughts, plans, and attempts), substance use, and bullying victimization are higher among lesbian, gay, bisexual, transgender, and/or queer (LGBTQ +) youth compared to their heterosexual peers. However, research examining the interactive and potentially compounding associations of concurrent bullying and substance use (alcohol, cannabis, hallucinogens, and opioids) with STB is sparse, especially among LGBTQ + youth. Thus, the current study aims to understand how these substances moderate the association between bullying victimization and STB by utilizing data (N = 96,482) from the combined 2003-2019 Youth Risk Behavior Survey (YRBS). Using a cross-sectional design and hierarchical logistic regression, we found that, on average, LGBTQ + youth who were bullied were more likely to report planning to attempt suicide (O.R. = 2.71, p < .01). Similarly, youth who reported using opioids/prescription drugs (O.R. = 4.60, p < .05) or hallucinogens (O.R. = 8.89, p < .01) were more likely to attempt suicide. No significant associations between alcohol use and STB were found. Lastly, cannabis emerged as a significant moderator of the associations between bullying victimization and suicidal ideation and plans, such that adolescents who were bullied and used cannabis were less likely to report suicidal ideation and planning compared to those who were bullied but did not use cannabis. These findings highlight that different substances are distinctively associated with STB among LGBTQ + youth, providing a better understanding of how individuals who are being bullied may cope and to develop prevention programs to combat suicidal thoughts, planning, and attempts.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"449-461"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Child and Caregiver Attendance in a Strengths-Focused, Culturally Grounded, Family-Based Program to Prevent Adverse Childhood Experiences.","authors":"Katie M Edwards, Emily A Waterman, Lorey A Wheeler, Weiman Xu, Ramona Herrington, Preciouse Trujllo, Skyler Hopfauf","doi":"10.1007/s11121-025-01796-w","DOIUrl":"10.1007/s11121-025-01796-w","url":null,"abstract":"<p><p>Little is known about factors that predict attendance in strengths-focused, culturally grounded, family-based programming to prevent adverse childhood experiences (ACEs) among Indigenous populations in the USA. An understanding of these factors may help to create initiatives to reduce barriers to attending programming that could reduce ACEs and other health inequities among structurally minoritized populations. The purpose of the current study was to explore this critical gap in the literature. Participants were 66 caregivers and their 107 children 10 to 14 (N = 66 families) randomly assigned to the treatment group. Baseline measures were used to predict program attendance (total number of sessions and any attendance). Results for caregivers showed that higher intimate partner violence victimization and perpetration and depression predicted program attendance (number of sessions and any attendance). For children, girls were more likely to attend at least one session than boys. Predictors of the total number of sessions for children included being a girl, lower depression, higher awareness (emotion regulation), higher parent-child communication, higher harsh parenting, higher caregiver positive reinforcement, and higher family cohesion. These findings have important implications for reducing potential barriers to program attendance as well as motivational interviewing approaches for specific subpopulations that may enhance attendance in a strengths-focused, culturally grounded, family-based programming to reduce ACEs.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"365-376"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailoring the Chicago Parent Program for Foster and Kinship Caregivers: a Mixed Methods Approach.","authors":"Sarah J Beal, Nathan Lutz, Meera Patel, Julie Dougherty, Ro Gigger, Lisa M Vaughn, Mary V Greiner, Amie F Bettencourt, Susan M Breitenstein, Debbie Gross, Robert T Ammerman","doi":"10.1007/s11121-025-01797-9","DOIUrl":"10.1007/s11121-025-01797-9","url":null,"abstract":"<p><p>There is a lack of evidence-based programs to support the prevention of child behavior problems designed specifically for foster and kinship caregivers from historically minoritized groups. Drawing on existing best-practice recommendations for tailoring interventions to new cultural and social contexts, this study evaluates initial evidence of the acceptability and feasibility of adapting the Chicago Parent Program (CPP) for foster and kinship care. An expert panel of foster and kinship caregivers, clinicians, and other professionals with experience in CPP and child welfare arenas was convened to review and adapt CPP materials in collaboration with researchers. The adapted program was then delivered to 12 foster and kinship caregivers, who completed surveys and qualitative interviews to provide feedback about the revised program. Caregiver satisfaction with the program was generally high. In interviews, caregivers emphasized that group sessions resonated with them (theme 1), that they appreciated the opportunity to connect with the program via mandated foster care clinic visits (theme 2), and that adapted components of the program delivery (theme 3), and materials (theme 4) were relevant. Caregivers also noted barriers with behavior management and logistical challenges that made it more difficult to attend regularly and complete practice assignments, which was reflected in reduced participation rates during the pilot. Overall, these findings suggest that careful and empirically driven adaptation to effective parent-focused prevention programs can be achieved for foster and kinship caregivers, leading to high potential impact for a population that has generally been under-resourced and experiences high need and mental health burden.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"377-390"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Prevention Behaviors among LGBTQ+ Adolescents: the Protective Role of LGBTQ+-Inclusive School Resources.","authors":"Samantha E Lawrence, Ryan J Watson, Amy L Gower, G Nic Rider, Kathryn Macapagal, Stephen T Russell, Marla E Eisenberg","doi":"10.1007/s11121-025-01799-7","DOIUrl":"10.1007/s11121-025-01799-7","url":null,"abstract":"<p><p>The objective of the present paper is to apply an intersectional lens to HIV prevention behavior disparities among LGBTQ+ adolescents across multiple social positions (racial, ethnic, gender, and sexual identities) and access to LGBTQ+-inclusive school resources (sex education and gender-sexuality alliances). Data are from the 2022 LGBTQ National Teen Survey (N = 10,871). Descriptive analyses and chi-square tests were conducted for social position, LGBTQ+-inclusive school resources, and HIV prevention variables. Social positions and two LGBTQ+-inclusive school resources were then entered into exhaustive chi-square automatic interaction detection models of HIV prevention behaviors (heard of/taken pre-exposure prophylaxis, HIV-testing, and consistent condom use). Groups with the highest and lowest prevalence of HIV prevention behaviors are described. LGBTQ+-inclusive school resources, especially sex education, were promotive of HIV prevention behaviors and mitigated some disparities across social positions. However, some disparities by social positions persisted. Gay or queer cisgender boys were consistently in the highest prevalence HIV prevention behavior groups, whereas youth who self-reported they were bisexual/pansexual, asexual, sexual identity questioning, straight or a sexual identity not listed, especially those who lacked LGBTQ+-inclusive school resources, were overrepresented in the low prevalence groups. LGBTQ+-inclusive school resources are important sources of HIV prevention information and may mitigate some HIV-related disparities.</p>","PeriodicalId":48268,"journal":{"name":"Prevention Science","volume":" ","pages":"438-448"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}