Palliative & Supportive Care最新文献_第2页

Why did you ask so many questions? 你为什么问那么多问题？

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-17 DOI: 10.1017/S1478951525100746

Alberto García-Salido

引用次数: 0

Promising results of a resource- and activity-oriented intervention integrating rehabilitation into palliative care in people with advanced cancer: A feasibility study testing outcome measures - CORRIGENDUM. 将康复纳入晚期癌症患者姑息治疗的资源和活动导向干预的有希望的结果：一项测试结果措施的可行性研究-勘误。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-17 DOI: 10.1017/S1478951525100643

Marie Brunsgaard Laursen, Marc Sampedro Pilegaard, Karen la Cour

引用次数: 0

Benefits of duloxetine may outweigh risks in a patient with hormone-positive breast cancer. 对于激素阳性乳腺癌患者，度洛西汀的益处可能大于风险。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-17 DOI: 10.1017/S1478951525100722

Gustavo Scannapieco Mastroleo, Kayley Ancy, Akhila Reddy

{"title":"Benefits of duloxetine may outweigh risks in a patient with hormone-positive breast cancer.","authors":"Gustavo Scannapieco Mastroleo, Kayley Ancy, Akhila Reddy","doi":"10.1017/S1478951525100722","DOIUrl":"10.1017/S1478951525100722","url":null,"abstract":"Objectives: Duloxetine is the only agent for chemotherapy-induced peripheral neuropathy (CIPN) recommended by the American Society of Clinical Oncology. As a moderate inhibitor of cytochrome P450 isoenzyme 2D6, duloxetine is theorized to decrease the efficacy of tamoxifen, which may be used to treat estrogen receptor-positive breast cancer. A case prompted our team to review the literature to elucidate the risks and benefits of duloxetine use in patients with this cancer.Methods: We present the case of a patient with estrogen receptor-positive breast cancer who was doing well on duloxetine for CIPN. Due to concern for the possible future need for tamoxifen, she was switched to multiple other agents, including venlafaxine, without success.Results: Ultimately, the patient was switched back to duloxetine due to persistent CIPN symptoms. The theoretical risk of tamoxifen interaction with duloxetine has not been demonstrated to be clinically significant in the literature.Significance of results: While emerging evidence suggests venlafaxine may prove an effective alternative, duloxetine remains the agent with the strongest evidence of benefit in patients with CIPN and must remain an option in this patient population.","PeriodicalId":47898,"journal":{"name":"Palliative & Supportive Care","volume":"23 ","pages":"e172"},"PeriodicalIF":2.1,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When memory fades, meaning remains: Personhood and palliative presence in dementia care. 当记忆消退，意义依然存在：痴呆症护理中的人格和姑息性存在。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S147895152510062X

Jose Eric Mella Lacsa

引用次数: 0

Effect of dignity therapy on meaning in life scores of cancer patients in palliative care. 尊严治疗对姑息治疗癌症患者生命意义评分的影响。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S147895152510045X

Michelle Uchida Miwa, Carlos Eduardo Paiva, Ana Julia Sucupira Ferreira, Miguel Julião, Harvey Max Chochinov, Welinton Yoshio Hirai, Ricardo Dos Reis, Bianca Sakamoto Ribeiro Paiva

{"title":"Effect of dignity therapy on meaning in life scores of cancer patients in palliative care.","authors":"Michelle Uchida Miwa, Carlos Eduardo Paiva, Ana Julia Sucupira Ferreira, Miguel Julião, Harvey Max Chochinov, Welinton Yoshio Hirai, Ricardo Dos Reis, Bianca Sakamoto Ribeiro Paiva","doi":"10.1017/S147895152510045X","DOIUrl":"10.1017/S147895152510045X","url":null,"abstract":"Objectives: Dignity Therapy (DT) helps reframe and give meaning to the illness process of the terminally ill individual. This study aims to evaluate the effect of DT on meaning in life scores and, additionally, to assess how much DT can alleviate physical and emotional symptoms in cancer patients undergoing palliative care.Methods: This was a before-and-after clinical trial, involving the recruitment of 30 patients hospitalized in a palliative care unit, who filled out the Edmonton Symptom Assessment Scale (ESAS) and the Meaning in Life Scale (MiLS) both before and after the implementation of DT.Results: Of the 40 patients invited to participate in the study, DT was completed by 30 (75%) participants: 22 (73%) women and 8 (27%) men. Eighteen (60%) patients died during hospitalization, while 12 (40%) were discharged. When analyzing the factors correlated with the MiLS scores, a positive association was identified between the emotional and physical domains of the ESAS, and a negative association with the total ESAS score, spiritual ESAS score, male gender, higher educational level, and a cancer diagnosis duration (>6 years).Significance of results: DT contributed to clinically relevant improvement, albeit not statistically significant, observed in emotional and spiritual well-being, as well as in the meaning of life. This underscores the importance of considering DT for palliative care patients nearing death.","PeriodicalId":47898,"journal":{"name":"Palliative & Supportive Care","volume":"23 ","pages":"e170"},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An existential perspective on physician-assisted dying in contemporary legislative debates. 当代立法辩论中医生协助死亡的存在主义视角。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S1478951525100606

Artin A Mahdanian

引用次数: 0

Prognostic discussions in patients with advanced lymphoma: Characteristics and challenges. 晚期淋巴瘤患者的预后讨论：特点和挑战。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S147895152510059X

Meghan McDarby, Jaime Gilliland, Rinchen Dolma, Sarah C Rutherford, Peter Martin, Holly Prigerson, Kelly M McConnell

{"title":"Prognostic discussions in patients with advanced lymphoma: Characteristics and challenges.","authors":"Meghan McDarby, Jaime Gilliland, Rinchen Dolma, Sarah C Rutherford, Peter Martin, Holly Prigerson, Kelly M McConnell","doi":"10.1017/S147895152510059X","DOIUrl":"10.1017/S147895152510059X","url":null,"abstract":"Objectives: Prognostic discussions are critical in the care of patients with advanced lymphoma, given the disease's complexity, rapidly evolving treatments, and shifting potential for cure. However, previous research has paid limited attention to how these discussions unfold from both patient and clinician perspectives, particularly in the context of early conversations. The current study sought to identify key experiences that inform improvements in clinician communication and patient understanding of prognosis for patients with advanced lymphoma.Methods: We conducted a qualitative study from July 2023 to June 2024 with 19 patients diagnosed with advanced lymphoma and 3 oncologists. Semi-structured interview transcripts were analyzed using thematic content analysis, and emergent themes were identified through consensus among a trained coding team.Results: Two primary themes emerged. First, patients recalled early prognostic conversations as highly focused on curative intent. Second, oncologists cited incomplete diagnostic data and concerns about overwhelming patients as reasons for limiting early discussions, often delaying deeper prognostic conversations. Clinicians reported tension between maintaining patient hope and providing comprehensive information about disease trajectory and treatment uncertainty.Significance of results: Findings highlight a need for communication strategies that balance hope with realism in early prognostic discussions for patients with advanced lymphoma. Oncologists may benefit from structured, evidence-based guidance to manage information delivery over time, particularly in the face of diagnostic ambiguity. Future research should prioritize inclusive sampling and explore timing and content of ongoing prognostic discussions to better support informed decision-making and goal-concordant care.","PeriodicalId":47898,"journal":{"name":"Palliative & Supportive Care","volume":"23 ","pages":"e164"},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating psychospiritual counseling in glioblastoma care: Enhancing resilience and spiritual well-being for improved survival outcomes. 在胶质母细胞瘤护理中整合心理精神咨询：增强恢复力和精神幸福感以改善生存结果。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S1478951525100540

Rizky Andana Pohan, Dian Oktary, Riza Amalia, Putri Bunga Aisyah Pohan, Bambang Prastio

引用次数: 0

Bridging the ACP literacy gap in Nigeria: A call for community and cross-sector collaboration. 弥合尼日利亚ACP扫盲差距：呼吁社区和跨部门合作。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S1478951525100631

Rikas Saputra, Isnaria Rizki Hayati, Neni Noviza, Yenni Lidyawati

引用次数: 0

Coping strategies as modifiable pathways to posttraumatic growth in young adults facing parental cancer. 应对策略是面对父母癌症的年轻人创伤后成长的可改变途径。

IF 2.1 4区医学

Palliative & Supportive Care Pub Date : 2025-09-12 DOI: 10.1017/S1478951525100448

Erma Pratiwi Nufi, Alber Tigor Arifyanto, Minarti Usman, Wa Ode Lili Andriani Nasri, Ismail Ismail

引用次数: 0