World Journal of Orthopedics最新文献

{"title":"Cross-talks between osteoporosis and gut microbiome.","authors":"Shiva Shankar Jha, Naveen Jeyaraman, Madhan Jeyaraman, Swaminathan Ramasubramanian, Sathish Muthu, Gabriel Silva Santos, Lucas Furtado da Fonseca, José Fábio Lana","doi":"10.5312/wjo.v16.i3.102274","DOIUrl":"10.5312/wjo.v16.i3.102274","url":null,"abstract":"<p><p>The gut microbiome comprises a vast community of microbes inhabiting the human alimentary canal, playing a crucial role in various physiological functions. These microbes generally live in harmony with the host; however, when dysbiosis occurs, it can contribute to the pathogenesis of diseases, including osteoporosis. Osteoporosis, a systemic skeletal disease characterized by reduced bone mass and increased fracture risk, has attracted significant research attention concerning the role of gut microbes in its development. Advances in molecular biology have highlighted the influence of gut microbiota on osteoporosis through mechanisms involving immunoregulation, modulation of the gut-brain axis, and regulation of the intestinal barrier and nutrient absorption. These microbes can enhance bone mass by inhibiting osteoclast differentiation, inducing apoptosis, reducing bone resorption, and promoting osteoblast proliferation and maturation. Despite these promising findings, the therapeutic effectiveness of targeting gut microbes in osteoporosis requires further investigation. Notably, gut microbiota has been increasingly studied for their potential in early diagnosis, intervention, and as an adjunct therapy for osteoporosis, suggesting a growing utility in improving bone health. Further research is essential to fully elucidate the therapeutic potential and clinical application of gut microbiome modulation in the management of osteoporosis.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 3","pages":"102274"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting outcomes of indirect decompression after oblique and lateral lumbar interbody fusions.","authors":"Kyle M M Behrens, Hossein Elgafy","doi":"10.5312/wjo.v16.i3.100772","DOIUrl":"10.5312/wjo.v16.i3.100772","url":null,"abstract":"<p><p>In this editorial, the authors of this paper comment on the article by Bokov <i>et al</i> published in the recent issue of <i>World Journal of Orthopedics</i>. We reviewed a general overview of oblique lumbar interbody fusions (OLIF) and lateral lumbar interbody fusions (LLIF), their indications and complications as an increasingly popular minimally invasive technique to address several lumbar pathologies. This editorial thoroughly discusses and reviews the literature regarding factors affecting outcomes of indirect decompression utilized through OLIF and LLIF procedures. Several parameters play a critical role in patient outcomes including restoration of disc height, foraminal height, central canal squared, and foraminal area. The indirect decompression allows for unbuckling of the ligamentum flavum which can significantly decompress the neural elements as well as aid in reduction of spondylolisthesis. However, the authors further highlight the limitations of indirect decompression and factors that may predict unsuccessful outcomes including bony foraminal stenosis, severe central canal stenosis, and osteoporosis. As a result, failure of indirect decompression can lead to persistent pain, radiculopathy and unsatisfied patients. Spinal surgeons may be left to reimage patients and consider additional procedures with direct decompression.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 3","pages":"100772"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trabecular titanium acetabular cup in patients with medial femoral neck fracture: Survivorship analysis and clinical and radiological outcomes.","authors":"Eugenio Jannelli, Ester Boggio, Alberto Castelli, Gianluigi Pasta, Federico Alberto Grassi, Mario Mosconi","doi":"10.5312/wjo.v16.i3.100481","DOIUrl":"10.5312/wjo.v16.i3.100481","url":null,"abstract":"<p><strong>Background: </strong>Clinical studies using Trabecular Titanium™ acetabular cups have shown promising short and medium-term results. This material, due to its macro and micro surface roughness, provides a substrate for osseointegration and enhances implant stability. However, there is a lack of evidence in the literature on the use of this material in patients with femoral neck fracture.</p><p><strong>Aim: </strong>To evaluate the short-term clinical-functional and radiographic outcomes in patients with femoral neck fractures undergoing total hip arthroplasty (THA) with Trabecular Titanium™ acetabular cup implants.</p><p><strong>Methods: </strong>The study included 104 patients with medial femoral neck fractures who underwent THA between January 2020 and December 2020 with the Delta TT acetabular cup (Lima Corporate, Villanova di San Daniele del Friuli, Italy). The mean age of the patients was 69.57 ± 10.16 years (range: 36-85 years). The follow-up period ranged from a minimum of 3 to a maximum of 4 years. Three questionnaires (Harris Hip Score, Oxford Hip Score, and EQ5D) were administered along with radiographic evaluations. Statistical methods included the Student's <i>t</i>-test and one-way analysis of variance for comparisons (with significance set at 0.05), and the Kaplan-Meier curve for prosthetic implant survival.</p><p><strong>Results: </strong>The mean follow-up was 41.5 months. The Harris Hip Score (HHS) showed a mean increase of 2.74 points (mean HHS 88.52 at 6 months postoperatively and mean HHS 91.26 at the last follow-up) with statistical significance. Similarly, the Oxford Hip Score demonstrated a statistically significant difference between follow-up groups. However, the EQ5D did not show statistically significant differences among the three groups (preoperative, 6-month follow-up, and last follow-up). Revision surgery was required in 6 patients. According to Moore's criteria, 96% of the acetabular components were radiographically stable and well-integrated at the last follow-up. The Kaplan-Meier curve showed a 96% survival rate.</p><p><strong>Conclusion: </strong>The clinical and radiographic results obtained in the short to medium term confirm the excellent performance of the Delta TT acetabular cup in terms of osseointegration, providing an optimal solution both for young patients with high functional recovery demands and for fragile patients requiring optimal stability of the acetabular component to reduce the risk of implant failure.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 3","pages":"100481"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteosarcopenia and geriatric hip fractures: Current concepts.","authors":"Theodoros Tosounidis, Lefteris Manouras, Byron Chalidis","doi":"10.5312/wjo.v16.i3.102930","DOIUrl":"10.5312/wjo.v16.i3.102930","url":null,"abstract":"<p><p>According to World Health Organization, one in six people will be older than 60 by 2030. The rising life expectancy is anticipated to contribute to a subsequent increase of geriatric fractures worldwide. Osteosarcopenia, which is the coexistence of osteoporosis and sarcopenia, greatly affects older people. Recent studies have tried to identify the prevalence of osteosarcopenia in older populations as well as its correlation with fragility fractures such as hip fractures. The latter pose a major burden on both health loss and costs worldwide. Increasing amount of evidence suggests that osteosarcopenia in patients with hip fractures contributes to higher rates of mortality and complications. At the same time, research focuses on the molecular basis of the interplay between osteoporosis and sarcopenia by utilizing genomic or proteomic approaches. These promising studies could reveal potential preventive or diagnostic biomarkers to optimize the management of osteosarcopenia in hip fractures patients. The fact that bones and muscle can also function as endocrine organs further highlights the complex relationship between osteoporosis and sarcopenia, underscoring the need for a better understanding of the role of myokines and osteokines in osteosarcopenia. Finally, the impact of osteosarcopenia on pain management and rehabilitation after hip fracture surgery, requires further assessment.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 3","pages":"102930"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of WARP sequence magnetic resonance imaging with the removal of metal artifacts in the evaluation of lumbar adjacent.","authors":"Wei Xu, Meng-Yun Xiong, Yi Wang, Qi-Feng Yu, Xiao-Jian Ye, Si-Lian Wang, Zhi-Kun Li","doi":"10.5312/wjo.v16.i3.103169","DOIUrl":"10.5312/wjo.v16.i3.103169","url":null,"abstract":"<p><strong>Background: </strong>Posterior lumbar interbody fusion has good clinical results, but adjacent segment disease (ASD) affects its long-term efficacy. In patients with L4-5 fusion who were followed up for more than 10 years, the ASD incidence was 33.3%. Magnetic resonance imaging (MRI) is key for ASD diagnosis, but metal artifacts from internal fixation limit its use; therefore, removing the artifacts is crucial for ASD diagnosis and treatment.</p><p><strong>Aim: </strong>To evaluate the value of WARP MRI for patients with lumbar ASD.</p><p><strong>Methods: </strong>In our hospital, the lumbar spines of patients with ASD were assessed <i>via</i> lumbar MRI, including conventional sequences and sequences for artifacts. A PACS workstation was used for image measurement, analysis, and assessment, which mainly included measurement of the internal fixation implant artifact area, evaluation of the visibility of the anatomical structures surrounding the implant, and diagnostic assessment of ASD in the section. Conventional MRI data sequences and artifacts to sequence the contrast analysis of the MRI data.</p><p><strong>Results: </strong>A total of 30 patients with ASD after lumbar fusion and internal fixation were included in the study; the patients included 13 male and 17 female patients and were aged 66.03 ± 5.83 years. The metal artifact area of the WARP T2-tirm sequence was significantly smaller than that of the conventional STIR sequence [(20.85 ± 6.27) cm² <i>vs</i> (50.56 ± 8.55) cm², <i>P</i> < 0.01]. The WARP T2-tirm sequence was observed around the implants, pedicles, intervertebral foramen, and vertebral bodies, and the conventional STIR sequence clearly displayed nerve roots within the intervertebral foramen. In all 30 patients, all adjacent segments of the WARP T2-tirm sequence could be clearly observed (above Grade 4), whereas it was difficult to observe these segments in the conventional STIR sequence due to the presence of more severe metal artifacts.</p><p><strong>Conclusion: </strong>WARP sequences can significantly reduce the artifact area in the sagittal and cross-sectional images of titanium alloy spinal fixation, providing a good imaging reference for the diagnosis of ASD.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 3","pages":"103169"},"PeriodicalIF":2.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Return to work and resumption of driving after anterior minimally invasive total hip arthroplasty.","authors":"Hisatoshi Ishikura, Yuji Masuyama, Sho Fujita, Takeyuki Tanaka, Sakae Tanaka, Toru Nishiwaki","doi":"10.5312/wjo.v16.i2.103817","DOIUrl":"https://doi.org/10.5312/wjo.v16.i2.103817","url":null,"abstract":"<p><strong>Background: </strong>Return to work (RTW) and resumption of driving (ROD) are critical factors that influence postoperative quality of life in patients undergoing total hip arthroplasty (THA). However, few studies have focused on the minimally invasive (MIS) approach and its effect on these outcomes.</p><p><strong>Aim: </strong>To investigate RTW and ROD's timelines and influencing factors following anterior MIS-THA.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 124 patients who underwent anterior MIS-THA. Data on the demographics, occupational physical demands, and RTW/ROD timelines were also collected. Clinical outcomes were measured using standardised scoring systems. Statistical analyses were performed to evaluate the differences between the groups based on employment status and physical workload.</p><p><strong>Results: </strong>Among employed patients, the RTW rate was 94.7%, with an average return time of five weeks. The average ROD time was 3.5 weeks across all patients. Despite similar postoperative clinical scores, RTW time was significantly influenced by occupations' physical workload, with heavier physical demands associated with delayed RTW.</p><p><strong>Conclusion: </strong>Anterior MIS-THA facilitates early RTW and ROD, particularly in occupations with lower physical demands. These findings highlight the importance of considering occupational and physical workload in postoperative care planning to optimize recovery outcomes.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 2","pages":"103817"},"PeriodicalIF":2.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Some artificial intelligence tools may currently be useful in orthopedic surgery and traumatology.","authors":"Emerito Carlos Rodriguez-Merchan","doi":"10.5312/wjo.v16.i2.102252","DOIUrl":"https://doi.org/10.5312/wjo.v16.i2.102252","url":null,"abstract":"<p><p>Artificial intelligence (AI) can help in diagnosing fractures and demonstrating effusions, dislocations, and focal bone lesions in both adult and pediatric aged individuals and also aid in early tumor discovery (bone osteosarcoma) and in robot-assisted surgery. A recent AI model [Mask R-CNN (region-based convolutional neural network)] has shown to be dependable for detecting surgical target zones in pediatric hip and periarticular infections, offering a more convenient and quicker alternative to conventional methods. It can help inexperienced physicians in pre-treatment evaluations, diminishing the risk of missed diagnosis and misdiagnosis. AI has some very interesting applications in orthopedic surgery, which orthopedic surgeons should be aware of and if possible use. Although some interesting advances have been made recently on AI in orthopedic surgery, its usefulness in clinical practice is still very limited. Ethical concerns, such as transparency in AI decision-making, data privacy, and the potential loss of human intuition cannot be forgotten. Besides, it is paramount to explore how to gain trust from both healthcare professionals and patients in the utilization of AI.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 2","pages":"102252"},"PeriodicalIF":2.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of sub-acromial injections in rotator cuff injuries: A systematic review and meta-analysis.","authors":"Luana Tossolini Goulart, Fabio Teruo Matsunaga, Joao Carlos Belloti, Nicola Archetti Netto, Thays Sellan Paim, Marcel Jun Sugawara Tamaoki","doi":"10.5312/wjo.v16.i2.102856","DOIUrl":"https://doi.org/10.5312/wjo.v16.i2.102856","url":null,"abstract":"<p><strong>Background: </strong>Sub-acromial injections are a therapeutic option for rotator cuff injuries; however, evidence regarding the most effective drug in this context is unclear, which needs to be investigated.</p><p><strong>Aim: </strong>To evaluate the effectiveness of various sub-acromial injections for rotator cuff injuries.</p><p><strong>Methods: </strong>We conducted a systematic review and pair-wise and network meta-analyses of randomized clinical trials (RCTs) comparing sub-acromial injections for rotator cuff injuries. The interventions evaluated were hyaluronic acid (HA), platelet-rich plasma (PRP), prolotherapy, and corticosteroids. The outcomes of interest were pain and functional improvement, which were evaluated with standardized scores. The Risk of Bias 2 tool and the Grading of Recommendations, Assessment, Development and Evaluation methodology were used to assess data quality.</p><p><strong>Results: </strong>Twenty RCTs, comprising 1479 participants, were included. In the short term, HA achieved the best outcomes [pain mean difference (MD) = -1.48, 95% confidence interval (CI) -2.37 to -0.59; function MD = 10.18, 95%CI: 4.96-15.41]. In the medium term, HA, PRP, HA + PRP, and corticosteroids were not superior to placebo in improving pain. Based on function, HA + PRP was superior to placebo, corticosteroids, and PRP (MD = 26.72; 95%CI: 8.02-45.41). In the long term, HA, PRP, and corticosteroids were not superior to placebo in reducing pain. However, based on function, HA + PRP, PRP, and HA were superior to placebo, and HA + PRP had the best result (MD = 36.64; 95%CI: 31.66-33.62).</p><p><strong>Conclusion: </strong>HA provides satisfactory short-term results, while HA with PRP demonstrates functional improvement in the medium and long terms. However, no intervention maintained the pain-relief effect on > 3-month follow-up.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 2","pages":"102856"},"PeriodicalIF":2.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periprosthetic fractures of the tibial shaft following long-stemmed total knee arthroplasty: A case report.","authors":"Maciej Kocon, Dariusz Grzelecki","doi":"10.5312/wjo.v16.i2.98674","DOIUrl":"https://doi.org/10.5312/wjo.v16.i2.98674","url":null,"abstract":"<p><strong>Background: </strong>Periprosthetic fractures of the tibia are uncommon complications after total knee arthroplasty (TKA). Therefore, there is still clinical debate regarding the appropriate treatment method. This study presents the case of a patient with two successive periprosthetic fractures of the tibial shaft treated with revision TKA (rTKA) and intramedullary fixation.</p><p><strong>Case summary: </strong>A 65-year-old woman was treated for tibial shaft pseudarthrosis after a periprosthetic fracture. The patient underwent rTKA with a tibial component exchange to a long-stemmed implant. At her 1.5-year follow-up visit, partial asymptomatic bone union was noted with no prosthesis loosening. The patient achieved 0° to 120° range of motion and a stable knee, and reported high satisfaction. Improvements were observed in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) from 74 to 17, and in the knee society scores (KSS) from 56 to 91 (clinical) and 10 to 80 (functional). After 2.5 years, the patient sustained a second fracture below the original site due to low-energy trauma. The rTKA with intramedullary stabilization was performed. One year later, WOMAC and clinical and functional KSS were 15, 81, and 80, respectively. Despite tibial shortening and lower limb inequality, the patient remains very satisfied and does not experience any issues with daily activities nor weight-bearing.</p><p><strong>Conclusion: </strong>There is little consensus in the literature on the management of tibial shaft periprosthetic fractures. Intramedullary stabilization may yield excellent outcomes, but individual case discussion is necessary for rTKA indications.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 2","pages":"98674"},"PeriodicalIF":2.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidden dangers of pelvic fracture: A meta-analysis on urinary tract injury incidence and risk factors.","authors":"Gonzalo Mariscal, Ali Dway, Carlos Barrios","doi":"10.5312/wjo.v16.i2.102483","DOIUrl":"https://doi.org/10.5312/wjo.v16.i2.102483","url":null,"abstract":"<p><strong>Background: </strong>Pelvic fractures are often associated with significant morbidity, including injuries to the urinary tract. Understanding the incidence and risk factors for urinary tract injury in these patients is crucial for prompt diagnosis and management. This meta-analysis aims to synthesize existing evidence to determine the overall incidence and identify specific risk factors associated with urinary tract injuries in patients with pelvic fractures.</p><p><strong>Aim: </strong>To determine the incidence and risk factors for urinary tract injuries in patients with pelvic fractures.</p><p><strong>Methods: </strong>A systematic search of PubMed, EMBASE, Scopus, and the Cochrane Library was conducted without date restrictions. Studies examining the incidence and risk factors of urinary tract injuries in patients with pelvic fractures were included. Data extracted included demographics, injury mechanism, pelvic fracture type, urinary tract injury incidence, mortality, and discharge disposition. Review Manager 5.4 was used for data analysis.</p><p><strong>Results: </strong>Ten studies comprising 22700 patients were included. The pooled incidence of urinary tract injury associated with pelvic fracture was 6.88% (95%CI: 6.20%-7.55%). Vehicle, motorcycle, and pedestrian accidents were identified as risk factors for urinary tract injury, with relative risks (RR) of 1.08 (95%CI: 1.06-1.11), 1.89 (95%CI: 1.78-2.00), and 1.53 (95%CI: 1.20-1.95), respectively. Pubic fracture and pelvic ring disruption were significantly associated with urinary tract injury [odds ratio (OR) 1.94, 95%CI: 1.09-3.44 and OR 5.53, 95%CI: 4.67-6.54, respectively)]. Patients without urinary tract injury were more likely to be discharged home (RR 0.79, 95%CI: 0.67-0.92). Mortality was higher in patients with urinary tract injury (OR 1.92, 95%CI: 1.77-2.09).</p><p><strong>Conclusion: </strong>Urinary tract injury occurs in nearly 7% of patients with pelvic fractures. Motorcycle accidents, pubic fractures, and pelvic ring disruptions are significant risk factors. Urinary tract injury following pelvic fracture is associated with increased mortality.</p>","PeriodicalId":47843,"journal":{"name":"World Journal of Orthopedics","volume":"16 2","pages":"102483"},"PeriodicalIF":2.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}