Turan Deniz Ergun , Mustafa Anil Topal , Peter M. ten Klooster , Gerben J. Westerhof , Ernst T. Bohlmeijer , Lonneke I.M. Lenferink
{"title":"Daily life after the death of a loved one: A systematic review of daily diary and ecological momentary assessment studies","authors":"Turan Deniz Ergun , Mustafa Anil Topal , Peter M. ten Klooster , Gerben J. Westerhof , Ernst T. Bohlmeijer , Lonneke I.M. Lenferink","doi":"10.1016/j.ijchp.2026.100693","DOIUrl":"10.1016/j.ijchp.2026.100693","url":null,"abstract":"<div><div>The death of a loved one is a common yet potentially traumatic event that can impact bereaved people’s daily lives substantially. However, bereavement experiences have been investigated mostly with cross-sectional surveys, which provide limited information about bereaved people’s everyday functioning. Intensive longitudinal methods (ILM) that collect self-reports once (daily diary; DD) or multiple times (ecological momentary assessment; EMA) a day allow researchers to examine momentary variations in bereaved people’s everyday experiences. In this preregistered study, we aimed to systematically review studies that investigated the daily life of bereaved people using ILM. We searched for English peer-reviewed journal articles in Scopus, PubMed, and PsycINFO. After title, abstract, and full-text screening of 230 records, 18 articles were included in the final review. Fourteen studies used DD, and four used EMA designs. Studies examined four topics: a) the acceptability, feasibility, and reactivity effects of ILM among bereaved people, b) emotions and emotion regulation strategies, c) sleep quality, and d) romantic relationships. While the acceptability, feasibility, and reactivity effects of ILM were investigated by both DD and EMA studies, the latter three topics were examined only by DD studies. The studies show that DD and EMA are acceptable and feasible methods among bereaved people. DD studies showed that experiences of positive emotions and affectionate touch were related to better psychological outcomes, such as intimacy, while there were inconsistent associations between grief and sleep quality. ILMs appear to offer valuable yet largely untapped potential for capturing dynamic experiences of grief in bereavement research.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100693"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diogo Branco , Mariana Castro Fernandes , Sergi Bermúdez i Badia , Ana Lúcia Faria
{"title":"Emotional Daily Life Library (E-DLL): Validation of a database of 3D objects for emotion elicitation","authors":"Diogo Branco , Mariana Castro Fernandes , Sergi Bermúdez i Badia , Ana Lúcia Faria","doi":"10.1016/j.ijchp.2026.100690","DOIUrl":"10.1016/j.ijchp.2026.100690","url":null,"abstract":"<div><div>Research on emotional perception often relies on 2D stimuli or highly affective images, limiting ecological validity. We introduce the Emotional Daily Life Library (E-DLL), a database of 132 rotating 3D everyday objects with comprehensive perceptual, cognitive, and emotional normative ratings. In 52 adults, participants provided dimensional (valence–arousal–dominance) and categorical emotion ratings, alongside assessments of recognition, naming, familiarity, contact, usage, and visual complexity. Personality traits (NEO-FFI) and depressive symptoms (BDI-II) were measured to examine individual differences.</div><div>Cumulative Link Mixed Models (CLMMs) revealed that valence ratings were negatively influenced by the interaction of Neuroticism and subclinical depressive symptoms. For arousal, higher Neuroticism and Conscientiousness demonstrated marginal positive associations, while dominance ratings were unaffected. Generalized Linear Mixed Models (GLMMs) for categorical labels indicated that while emotional attributions were primarily driven by stimulus properties, traits such as Neuroticism and Extraversion significantly predicted the perception of negative emotions (e.g., Sadness). Spearman correlations identified interrelationships among cognitive and perceptual dimensions, and redundant variables (Contact and Usage) were combined into a composite Object Interaction score.</div><div>By integrating neutral, immersive 3D stimuli with rich multidimensional annotations, E-DLL provides a controlled and ecologically valid tool for experimental and clinical research. Its applicability includes cognitive training, VR-based interventions, and personalized neurorehabilitation platforms such as NeuroAIreh@b, supporting investigations of affective biases and optimizing daily life–oriented therapeutic interventions.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100690"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147952976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siyu Pan, Peng Wang, Fabian Herold, Matthew Heath, Edmund Wei Jian Lee, Effie Lai-Chong Law, Cassandra J. Lowe, André Werneck, Markus Gerber, David Moreau, Myrto Mavilidi, Fred Paas, Mats Hallgren, Xia Xu, Liye Zou
{"title":"Accelerometer-derived movement phenotypes and adolescent mental health in pediatric obesity: A causal machine-learning study","authors":"Siyu Pan, Peng Wang, Fabian Herold, Matthew Heath, Edmund Wei Jian Lee, Effie Lai-Chong Law, Cassandra J. Lowe, André Werneck, Markus Gerber, David Moreau, Myrto Mavilidi, Fred Paas, Mats Hallgren, Xia Xu, Liye Zou","doi":"10.1016/j.ijchp.2026.100704","DOIUrl":"10.1016/j.ijchp.2026.100704","url":null,"abstract":"<div><h3>Background</h3><div>Children with overweight or obesity are at elevated risk for later-life mental health challenges, but the role of accelerometer-derived waking movement behaviors remains uncertain. Thus, we examined longitudinal associations of sedentary behavior (SB), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) at age 7 with later-life internalizing and externalizing problems.</div></div><div><h3>Method</h3><div>We used data from the UK Millennium Cohort Study, focusing on children with overweight or obesity at age 7 who had valid accelerometer data and a complete set of predefined analytic variables (N = 858). Exposures were average daily minutes of SB, LPA, and MVPA. Outcomes were parent-reported Strengths and Difficulties Questionnaire-based internalizing and externalizing problems scores at ages 11 and 14. A generalized random forests approach was used to estimate average treatment effects (ATEs) and conditional average treatment effects (CATEs), adjusted for relevant demographic, socioeconomic, body mass index, parental distress, baseline mental health, and co-occurring movement intensities; day-of-week activity-pattern variables were used as exploratory candidate moderators.</div></div><div><h3>Results</h3><div>Estimated ATEs were small. After applying the Benjamini-Hochberg false-discovery-rate (FDR) correction across the 12 primary exposure-outcome tests, only the association between higher SB and lower internalizing problems at age 11 remained statistically significant (ATE = -0.013 SDQ points per additional min/day; 95% CI, -0.019 to -0.007; q < 0.001). No other pathway survived FDR correction, and other nominal or directionally suggestive estimates were interpreted as exploratory. CATE summaries and calibration tests provided limited evidence of reproducible heterogeneity.</div></div><div><h3>Conclusions</h3><div>Accelerometer-derived waking movement behaviors at age 7 were associated with later SDQ problems scores in small and outcome-specific ways among children with overweight or obesity. Since the study is based on observational data and relies on measured-confounder assumptions, the findings should be interpreted cautiously, and as model-based estimates rather than definitive causal evidence.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100704"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Youngju Lee , Yongseong Lee , Yujeong Kim, Dongha Lee
{"title":"Sensory modality affects emotional dimension perception and frontoparietal brain responses","authors":"Youngju Lee , Yongseong Lee , Yujeong Kim, Dongha Lee","doi":"10.1016/j.ijchp.2026.100699","DOIUrl":"10.1016/j.ijchp.2026.100699","url":null,"abstract":"<div><div>The ability to perceive other people’s emotions is essential for social interaction and communication. Emotion perception involves complex cognitive processes triggered by visual, auditory, or both stimuli. However, it remains unclear how people use auditory, visual, and combined audiovisual cues to evaluate emotional valence and arousal. To address this, we conducted an emotion perception task using functional near-infrared spectroscopy to measure frontoparietal brain responses. Seven emotion categories (Angry, Calm, Disgust, Fear, Happy, Sad, and Surprise) portrayed by actors were presented under three modality conditions: audio-only (AO), audiovisual (AV), and video-only (VO). We observed significant differences between AO, AV, and VO in the behavioral evaluation of emotional valence and arousal. In addition, AV showed significant activations for emotion categories in the frontoparietal network, but not for AO or VO. Moreover, brain-behavior relationships showed that higher oxygenated hemoglobin (HbO) activities were associated with more positive valence ratings in the VO condition, but with stronger arousal ratings in the AV condition. These findings reveal that sensory modality affects brain activity (HbO) and behavior evaluation (valence and arousal ratings) in the perception of emotional dimensions.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100699"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148241402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Madalena Raposo de Lima , Carla Pombo , Cátia Gameiro , Beatriz Lopes , Heitor Cardoso , Alexandre Bernardino , Maria Vania Silva Nunes
{"title":"Development of personalized exercogs for older adults care: A feasibility and single-arm study","authors":"Madalena Raposo de Lima , Carla Pombo , Cátia Gameiro , Beatriz Lopes , Heitor Cardoso , Alexandre Bernardino , Maria Vania Silva Nunes","doi":"10.1016/j.ijchp.2026.100674","DOIUrl":"10.1016/j.ijchp.2026.100674","url":null,"abstract":"<div><h3>Introduction</h3><div>The prevalence of mild cognitive impairment and dementia is rapidly increasing worldwide, profoundly impacting older adults’ quality of life and presenting significant challenges to healthcare systems. The heterogeneity of pathologies, the lack of customizable and available resources, and the scarcity of healthcare professionals are recurrent issues in aged care facilities. This study aimed to validate Exercogs®, a newly integrated portable exergaming platform designed to enhance cognitive function in older adults within elderly care facilities.</div></div><div><h3>Methodology</h3><div>We conducted two experiments: 1) a feasibility study with 12 healthcare professionals and 30 older adults to assess technology acceptance and usability, and 2) a single-arm pre-post study involving 204 seniors in aged care facilities to explore the potential multidimensional effects of the four Exercogs® (cognitive, affective, social, functional, and quality of life). The intervention was implemented over 12 weeks, with two weekly sessions.</div></div><div><h3>Results</h3><div>The intervention was well-received, with high-acceptance among older adults and healthcare professionals. Adherence was notably high (91.68%) with strong interest in continued use. Significant improvements were observed across multiple domains commonly impacted by aging, including cognition, mood, perceived loneliness, and quality of life, reflecting positive outcomes across all evaluated dimensions.</div></div><div><h3>Conclusion</h3><div>Preliminary results suggest that the Exercogs® is a promising tool to support healthcare professionals in aged care facilities. Future research should include a control group and randomized clinical trials to further validate these findings.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100674"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147747488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise-related changes in depressive symptoms and their association with anterior cingulate cortical thickness","authors":"Qi Xia, Qing Yu, Yuchen Li, Yuanpeng You, Xiaoqi Mo, Zijing Zhang, Chris Baeken, Luqing Wei, Guo-Rong Wu","doi":"10.1016/j.ijchp.2026.100712","DOIUrl":"10.1016/j.ijchp.2026.100712","url":null,"abstract":"<div><div>Aerobic exercise is associated with reduced depressive symptoms, but the neurobiological processes supporting this effect remain incompletely understood. We investigated whether short-term aerobic exercise reduces depressive symptoms in healthy young adults and whether such reduction is related to cortical structural change and neurotransmitter-receptor organization. Forty-eight participants completed a two-week aerobic running intervention and a two-week control period, with depressive symptoms and structural MRI assessed at baseline, week 2 and week 4. Aerobic exercise significantly reduced depressive symptoms relative to the control period. Across individuals, greater symptom reduction was associated with larger increases in anterior cingulate cortical thickness, an association observed only during the active intervention. The cortical map of this symptom–thickness association showed selective spatial correspondence with normative distributions of serotonergic 5-HT1A, 5-HT1B, 5-HT2A and 5-HT4 receptors, and the glutamatergic mGluR5 receptor, and this correspondence was observed only during the exercise period. These results indicate that short-term aerobic exercise is associated with changes in depressive symptoms and anterior cingulate structure. They also provide a neurobiologically informed context for understanding these exercise-related changes.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100712"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148737329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional reorganization of brain networks from childhood to adolescence: A multi-level approach","authors":"Merida Galilea Tapia-Medina, Raquel Cosío-Guirado, Maribel Peró-Cebollero, Cristina Cañete-Massé, Erwin Rogelio Villuendas-González, Joan Guàrdia-Olmos","doi":"10.1016/j.ijchp.2026.100700","DOIUrl":"10.1016/j.ijchp.2026.100700","url":null,"abstract":"<div><h3>Background/objective</h3><div>During childhood and adolescence, functional connectivity undergoes distinct age-related maturational trajectories within and between networks. However, normative connectivity patterns across development remain insufficiently characterized.</div></div><div><h3>Methods</h3><div>This study integrates voxel-wise degree centrality, degree centrality-derived seed-based connectivity, and network-level analyses to examine large-scale functional organization in a large multisite sample of 322 typically developing children (7–10.99 years) and adolescents (11–15 years) from the Autism Brain Imaging Data Exchange I and II repositories.</div></div><div><h3>Results</h3><div>Across all analytical levels, adolescents exhibited strengthened functional connectivity of subcortical hubs -the thalamus and the basal ganglia- with the Ventral Attention Network and Frontoparietal Network, emerging as the key hubs of network integration in adolescence. Children, by contrast, showed stronger functional connectivity within posterior sensory-perceptual nodes, particularly involving angular and occipital regions.</div></div><div><h3>Conclusions</h3><div>Our findings delineate a developmental reorganization from sensory-anchored functional architectures in childhood toward increasingly integrated subcortical, attentional and frontoparietal systems in adolescence, supporting emerging capacities for cognitive-control and goal-directed behavior. This multilevel characterization offers a normative reference framework for interpreting variability in neurodevelopment and, ultimately, for identifying potential early deviations.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100700"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13311167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yumeng Wang, Rong Bai, Jinmeng Liu, Shiyu Xu, Xia Liu
{"title":"Latent transition analysis of non-suicidal self-injury comorbidity patterns among adolescents: predictive roles of impulsivity, emotional dysregulation, and core self-evaluations","authors":"Yumeng Wang, Rong Bai, Jinmeng Liu, Shiyu Xu, Xia Liu","doi":"10.1016/j.ijchp.2026.100708","DOIUrl":"10.1016/j.ijchp.2026.100708","url":null,"abstract":"<div><div>Despite evidence that non-suicidal self-injury (NSSI) co-occurs with both emotional and behavioral problems in adolescence, little research has addressed their tripartite comorbidity. This study employed a person-centered approach to identify heterogeneous comorbidity patterns of NSSI with multiple emotional and behavioral problems, assess their stability and transitions, and explore associated risk and protective factors. A total of 3704 adolescents (57.1% males; <em>M</em>age = 14.0, SD = 0.83) participated in a two-wave, nine months study. Three distinct patterns were identified, including one <em>Low-symptoms</em> and two comorbidity patterns, namely the <em>Emotion-dominant, Low-NSSI Comorbidity</em> and <em>NSSI-dominant, High-symptoms Comorbidity</em>. Across time, adolescents showed three directions of change as stability, symptoms improvement, and symptoms worsening. Moreover, adolescents with higher impulsivity and emotional dysregulation were more likely to be classified into the comorbidity patterns, whereas those with higher core self-evaluation were less likely to belong to the comorbidity patterns. Longitudinally, higher core self-evaluation reduced the likelihood of symptoms worsening. These findings reveal the heterogeneous and fluid nature of the tripartite comorbidity among NSSI, emotional problems, and behavioral problems, and point to the value of integrative interventions that target emotion regulation, impulse control, and core self-evaluation.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100708"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond text: Using network centralities and AI models to detect suicide risk on Reddit","authors":"Golnaz Nikmehr, Aritz Bilbao-Jayo, Aitor Almeida","doi":"10.1016/j.ijchp.2026.100705","DOIUrl":"10.1016/j.ijchp.2026.100705","url":null,"abstract":"<div><div>Suicide prevention research increasingly leverages social media data, where individuals often share personal experiences and emotions. While most studies rely on textual analysis to detect suicidal ideation, the structural characteristics of online social networks remain underexplored. In this exploratory pilot-scale study, we investigate whether network centrality metrics derived from Reddit interaction graphs can provide complementary signals for suicide risk detection beyond text-centric approaches. We construct directed user interaction graphs and extract 14 centrality metrics, including degree, betweenness, eigenvector, authority, and Katz centralities, to evaluate their predictive power. Using traditional machine learning classifiers, we assess the performance of these graph-based features in distinguishing suicidal from non-suicidal users. To further explore the interplay between network structure and textual content, we integrate centrality features with Sentence-BERT (SBERT) embeddings within a Graph Neural Network (GNN) framework. Within the constraints of a small-scale dataset, the best-performing GNN with SBERT achieved 67% accuracy and a 67% F1-score, representing a marginal improvement over the Random Forest baseline (64% accuracy; F1 = 66%). Results show that network centralities alone provide meaningful signals of suicidal risk, revealing patterns of isolation, influence, and social connectedness that characterize vulnerable users. Although these findings provide preliminary evidence for the complementary value of structural network analysis, they should be interpreted cautiously due to dataset scale and keyword-based sampling constraints.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100705"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13320472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruoyi Xu, Huiyu Li, Hongwen Ma, Xiang Gao, Yaqin Zhou, Yanfei Jin
{"title":"Temporal biobehavioral pathways from perceived stress to symptom burden in patients with cancer: A three-wave longitudinal cross-lagged panel network analysis to inform supportive care","authors":"Ruoyi Xu, Huiyu Li, Hongwen Ma, Xiang Gao, Yaqin Zhou, Yanfei Jin","doi":"10.1016/j.ijchp.2026.100715","DOIUrl":"10.1016/j.ijchp.2026.100715","url":null,"abstract":"<div><h3>Background</h3><div>Cancer-related stress and symptom burden constitute a complex, interrelated process across psychological, biological, and functional domains. Existing studies often examine isolated associations, limiting understanding of their dynamic interactions over time. This study aimed to construct a cross-lagged panel network to examine the longitudinal temporal structure among perceived stress, emotional distress, inflammatory biomarkers, physical functioning, and symptoms.</div></div><div><h3>Methods</h3><div>A three-wave cross-lagged panel network (CLPN) analysis was conducted in oncology departments of two tertiary hospitals in Nanjing and Tianjin, China. A total of 276 patients completed baseline assessments; 258 and 241 completed follow-ups at 4–8 and 8–12 weeks post-treatment, respectively. Measures included perceived stress, emotional distress, biomarkers (C-reactive protein, interleukin-6, cortisol), functioning, and symptoms. Temporal associations were estimated using ridge-regularized CLPN models.</div></div><div><h3>Results</h3><div>Temporal networks revealed a consistent hierarchical organization of prospective cross-domain associations, with perceived stress occupying an early temporal position, and functioning and symptom-related variables occurring later in the temporal sequence. Bidirectional feedback was observed. Centrality analyses highlighted perceived stress and fatigue as prominent nodes.</div></div><div><h3>Conclusions</h3><div>Cancer symptom progression appears to follow a temporally organized hierarchical structure, with perceived stress serving as an early predictor. Fatigue functions as a key bridge across domains. These findings highlight the potential importance of early stress management and targeted fatigue interventions and may help inform phase-specific supportive care within multidisciplinary oncology practice.</div></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"26 2","pages":"Article 100715"},"PeriodicalIF":4.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148843423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}