Yulin Wang , Yun Tian , Zhiliang Long , Debo Dong , Qinghua He , Jiang Qiu , Tingyong Feng , Hong Chen , Masoud Tahmasian , Xu Lei
{"title":"Volume of the Dentate Gyrus/CA4 Hippocampal subfield mediates the interplay between sleep quality and depressive symptoms","authors":"Yulin Wang , Yun Tian , Zhiliang Long , Debo Dong , Qinghua He , Jiang Qiu , Tingyong Feng , Hong Chen , Masoud Tahmasian , Xu Lei","doi":"10.1016/j.ijchp.2023.100432","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100432","url":null,"abstract":"<div><h3>Background</h3><p>Emerging evidence increasingly suggests that poor sleep quality is associated with depressive symptoms. The hippocampus might play a crucial role in the interplay between sleep disturbance and depressive symptomatology, e.g., hippocampal atrophy is typically seen in both insomnia disorder and depression. Thus, examining the role of hippocampal volume in the interplay between poor sleep quality and depressive symptoms in large healthy populations is vital.</p></div><div><h3>Methods</h3><p>We investigated the association between self-reported sleep quality, depressive symptoms, and hippocampal total and subfields’ volumes in 1603 healthy young adults from the Behavioral Brain Research Project. Mediation analysis explored the mediating role of hippocampal volumes between sleep quality and depressive symptoms.</p></div><div><h3>Results</h3><p>Self-reported sleep quality and depressive symptoms were positively correlated. In addition, it negatively related to three hippocampal subfields but not total hippocampal volume. In particular, hippocampal subfield DG and CA4 volumes mediated the interrelationship between poor sleep quality and depressive symptoms.</p></div><div><h3>Conclusions</h3><p>Our findings improved the current understanding of the relationship between sleep disturbance, depressive symptomatology, and hippocampal subfields in healthy populations. Considering the crucial role of DG in hippocampal neurogenesis, our results suggest that poor sleep quality may contribute to depression through a reduction of DG volume leading to impaired neurogenesis which is crucial for the regulation of mood.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100432"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000686/pdfft?md5=e163e7e66c6c32701641835a1e26027d&pid=1-s2.0-S1697260023000686-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139090254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swathi Gujral , Marcia Burns , Kirk I Erickson , Dana Rofey , Jeremiah J Peiffer , Simon M. Laws , Belinda Brown
{"title":"Dose-response effects of exercise on mental health in community-dwelling older adults: Exploration of genetic moderators","authors":"Swathi Gujral , Marcia Burns , Kirk I Erickson , Dana Rofey , Jeremiah J Peiffer , Simon M. Laws , Belinda Brown","doi":"10.1016/j.ijchp.2024.100443","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100443","url":null,"abstract":"<div><h3>Background/Objective</h3><p>(1) Examine the role of exercise intensity on mental health symptoms in a community-based sample of older adults. (2) Explore the moderating role of genetic variation in brain-derived neurotrophic factor (<em>BDNF</em>) and apolipoprotein E (<em>APOE</em>) on the effects of exercise on mental health symptoms.</p></div><div><h3>Method</h3><p>This study is a secondary analysis of a three-arm randomized controlled trial, comparing the effects of 6 months of high-intensity aerobic training vs. moderate-intensity aerobic training vs. a no-contact control group on mental health symptoms assessed using the Depression, Anxiety, and Stress Scale (DASS). The <em>BDNF</em> Val66Met polymorphism and <em>APOE</em> ε4 carrier status were explored as genetic moderators of exercise effects on mental health symptoms.</p></div><div><h3>Results</h3><p>The exercise intervention did not influence mental health symptoms. The <em>BDNF</em> Val66Met polymorphism did not moderate intervention effects on mental health symptoms. <em>APOE</em> ε4 carrier status moderated the effect of intervention group on perceived stress over 6 months, such that <em>APOE</em> ε4 carriers, but not non-carriers, in the high-intensity aerobic training group showed a decline in perceived stress over 6 months.</p></div><div><h3>Conclusions</h3><p><em>APOE</em> ε4 carrier status may modify the benefits of high-intensity exercise on perceived stress such that <em>APOE</em> ε4 carriers show a greater decline in stress as a result of exercise relative to non-<em>APOE</em> ε4 carriers.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100443"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000085/pdfft?md5=290bfd18516f048e0f31ed1fcc5d5468&pid=1-s2.0-S1697260024000085-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139493496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meijun Hou , Fabian Herold , André O. Werneck , Megan Teychenne , Anthony G. Delli Paoli , Alyx Taylor , Tine Van Damme , Arthur F. Kramer , Mahbub M Hossain , Albert S Yeung , Neville Owen , Markus Gerber , Sebastian Ludyga , Boris Cheval , Liye Zou
{"title":"Associations of 24-hour movement behaviors with externalizing and internalizing problems among children and adolescents prescribed with eyeglasses/contact lenses","authors":"Meijun Hou , Fabian Herold , André O. Werneck , Megan Teychenne , Anthony G. Delli Paoli , Alyx Taylor , Tine Van Damme , Arthur F. Kramer , Mahbub M Hossain , Albert S Yeung , Neville Owen , Markus Gerber , Sebastian Ludyga , Boris Cheval , Liye Zou","doi":"10.1016/j.ijchp.2023.100435","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100435","url":null,"abstract":"<div><h3>Background</h3><p>Emerging evidence points towards the psychological benefits of meeting 24-hour movement behavior (24-HMB) guidelines, but such associations have not yet been investigated among children and adolescents of prescribed eyeglasses/contact lenses. To this end, we examined associations of meeting 24-HMB guidelines with internalizing and externalizing challenges in this population.</p></div><div><h3>Methods</h3><p>We used data from the 2021 National Survey of Children's Health, a cross-sectional survey including a representative sample of US children and adolescents. Data on movement behaviors (physical activity [PA], sedentary behavior operationalized via screen time [ST], and sleep duration [SL]) and internalizing and externalizing problems were collected through caregiver proxy reports. Caregivers completed questionnaires for 6030 (2799 girls) US children and adolescents of prescribed eyeglasses/contact lenses. Logistic regression analyses were conducted to determine the above-presented associations.</p></div><div><h3>Results</h3><p>Only 7.1 % of those prescribed eyeglasses/contact lenses met all three 24-HMB guidelines, while they were more likely to meet SL guideline alone (32.1 %) in relation to other independent guidelines including PA (2.5 %) and ST (10.9 %). Compared to not meeting any of the three 24-HMB guidelines, meeting at least two guidelines (25.22 %) was significantly linked to lower odds of internalizing problems and externalizing problems.</p></div><div><h3>Conclusion</h3><p>Meeting at least two components of the 24-HMB guidelines was beneficially linked to internalizing and externalizing problems. Thus, strategies or intervention programs that focus on meeting 24-HMB guidelines should be implemented among children and adolescents of those prescribed eyeglasses/contact lenses to foster coping with psychological issues.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100435"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000716/pdfft?md5=bb0b4f609895c0a3a57f293ebd532268&pid=1-s2.0-S1697260023000716-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuxiang Xu , Yongjie Li , Changqing Wang , Tingting Han , Yue Wu , Song Wang , Jianshe Wei
{"title":"Clinical value and mechanistic analysis of HIIT on modulating risk and symptoms of depression: A systematic review","authors":"Yuxiang Xu , Yongjie Li , Changqing Wang , Tingting Han , Yue Wu , Song Wang , Jianshe Wei","doi":"10.1016/j.ijchp.2023.100433","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100433","url":null,"abstract":"<div><h3>Background</h3><p>The exact causal mechanisms of depression remain unclear due to the complexity of the triggers, which has led to limitations in treating depression using modern drugs. High-intensity interval training (HIIT) is as effective as medication in treating depression without toxic side effects. Typically, HIIT requires less time commitment (i.e., shorter exercise duration) and exhibits pronounced benefits on depressive symptoms than other forms of physical exercise. This review summarizes the risk reduction and clinical effects of HIIT for depression and discusses the underlying mechanisms, providing a theoretical basis for utilizing HIIT in treating depression.</p></div><div><h3>Methods</h3><p>A database search was conducted in PubMed, Embase, Web of Science, and Scopus from inception up to October 2022. The methodological quality of the included literature was evaluated by the physiotherapy evidence database (PEDro) scale criteria. The review focused on evaluating the changes in depression risk or symptoms of HIIT interventions in healthy individuals, patients with depression, and patients with other disorders co-morbid with depression. Consequently, the mechanisms associated with depression related HIIT were summarized.</p></div><div><h3>Results</h3><p>A total of 586 participants (52 % female; mean age: 43.58±8.93 years) from 22 studies were included. Implementing HIIT using different exercise types alleviates depressive symptoms in individuals with depression and in individuals with depression who have exhibited comorbidities and reduced depression scale scores in subjects immediately after acute exercise. In addition, the long-interval HIIT and short-interval HIIT in the treatment of patients with cardiovascular or psychiatric disorders may reduce depressive symptoms via complex exercise-related changes on several levels, including by effecting the following measures: releasing monoamines, reducing neuronal death, inducing neurogenesis, modulating the functional homeostasis of the HPA axis, and enhancing the level of inflammation in the body.</p></div><div><h3>Conclusion</h3><p>HIIT is a relatively safe and effective antidepressant, which may involve multiple neurobiological mechanisms (release of monoamines, reducing neuronal death, inducing neurogenesis, modulating the functional homeostasis of the HPA axis, and enhancing the level of inflammation in the body), thereby reducing the risk or symptoms of depression in participants.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100433"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000698/pdfft?md5=6dd63eb74df736ca3a320e1918fc9888&pid=1-s2.0-S1697260023000698-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yongqing Hou , Guiping Qiu , Haishuo Xia , Tianbao He , Xiaoxian Liu , Antao Chen
{"title":"The specificity of the auditory P300 responses and its association with clinical outcomes in youth with psychosis risk syndrome","authors":"Yongqing Hou , Guiping Qiu , Haishuo Xia , Tianbao He , Xiaoxian Liu , Antao Chen","doi":"10.1016/j.ijchp.2024.100437","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100437","url":null,"abstract":"<div><h3>Background</h3><p>Schizophrenia often occurs in youth, and psychosis risk syndrome (PRS) occurs before the onset of psychosis. Assessing the neuropsychological abnormalities of PRS individuals can help in early identification and active intervention of mental illness. Auditory P300 amplitude defect is an important manifestation of attention processing abnormality in PRS, but it is still unclear whether there are abnormalities in the attention processing of rhythmic compound tone stimuli in PRS individuals, and whether the P300 amplitude induced by these stimuli is specific to PRS individuals and related to their clinical outcomes.</p></div><div><h3>Methods</h3><p>In total, 226 participants, including 122 patients with PRS, 51 patients with emotional disorders (ED), and 53 healthy controls (HC) were assessed. Baseline electroencephalography was recorded during the compound tone oddball task. The event-related potentials (ERPs) induced by rhythmic compound tone stimuli of two frequencies (20-Hz, 40-Hz) were measured. Almost all patients with PRS were followed up for 12 months and reclassified into four groups: PRS-conversion, PRS-symptomatic, PRS-emotional disorder, and PRS-complete remission. The differences in baseline ERPs were compared among the clinical outcome groups.</p></div><div><h3>Results</h3><p>Regardless of the stimulation frequency, the average P300 amplitude were significantly higher in patients with PRS than in those with ED (<em>p</em> = 0.003, <em>d</em> = 0.48) and in HC (<em>p</em> = 0.002, <em>d</em> = 0.44) group. The average P300 amplitude of PRS-conversion group was significantly higher than that of the PRS-complete remission (<em>p</em> = 0.016, <em>d</em> = 0.72) and HC group (<em>p</em> = 0.001, <em>d</em> = 0.76), and the average P300 amplitude of PRS-symptomatic group was significantly higher than that of the HC group (<em>p</em> = 0.006, <em>d</em> = 0.48). Regardless of the groups (PRS, ED, HC) or the PRS clinical outcome groups, the average P300 amplitude induced by 20-Hz tone stimulation was significantly higher than that induced by 40-Hz stimulation (<em>p</em>s < 0.001, Ƞ<sup>2</sup> = 0.074–0.082). The average reaction times of PRS was significantly faster than that of ED (<em>p</em> = 0.01, <em>d</em> = 0.38), and the average reaction times of the participants to 20-Hz target stimulation was significantly faster than that to 40-Hz target stimulation (<em>p</em> < 0.001, <em>d</em> = 0.21).</p></div><div><h3>Conclusion</h3><p>The auditory P300 amplitude induced by rhythmic compound tone stimuli is a specific electrophysiological manifestation of PRS, and the auditory P300 amplitude induced by compound tone stimuli shows promise as a putative prognostic biomarker for PRS clinical outcomes, including conversion to psychosis and clinical complete remission.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100437"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000024/pdfft?md5=bb041b763a9946f3f872012a9ac7a0f7&pid=1-s2.0-S1697260024000024-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Gostoli , Regina Subach , Francesco Guolo , Sara Buzzichelli , Giovanni Abbate Daga , John M. de Figueiredo , Chiara Rafanelli
{"title":"Demoralization in acute coronary syndrome: Treatment and predictive factors associated with its persistence","authors":"Sara Gostoli , Regina Subach , Francesco Guolo , Sara Buzzichelli , Giovanni Abbate Daga , John M. de Figueiredo , Chiara Rafanelli","doi":"10.1016/j.ijchp.2024.100444","DOIUrl":"10.1016/j.ijchp.2024.100444","url":null,"abstract":"<div><h3>Background/objective</h3><p>Although demoralization is associated with morbidity and mortality in cardiac settings, its treatment has been overlooked. The present randomized controlled trial aimed at 1) evaluating the effectiveness of sequential combination of Cognitive-Behavioral and Well-Being therapies (CBT/WBT), compared to Clinical Management (CM), on demoralization among Acute Coronary Syndromes (ACS) patients, at post-treatment and after 3 months; 2) examining ACS patients’ characteristics predicting demoralization persistence at 3-month follow-up.</p></div><div><h3>Method</h3><p>91 demoralized ACS patients were randomized to CBT/WBT (<em>N</em> = 47) or CM (<em>N</em> = 44). Demoralization was assessed with an interview on Diagnostic Criteria for Psychosomatics Research at baseline, post-treatment and 3-month follow-up. Predictors of demoralization maintenance included cardiac parameters, psychological distress and well-being.</p></div><div><h3>Results</h3><p>Compared to CM, CBT/WBT significantly reduced demoralization post-treatment. Somatization (odds ratio = 1.11; <em>p</em> = 0.027) and history of depression (odds ratio = 5.16; <em>p</em> = 0.004) were risk factors associated with demoralization persistence at follow-up, whereas positive relationships (odds ratio = 0.94; <em>p</em> = 0.005) represented protective factors.</p></div><div><h3>Conclusions</h3><p>The study provides preliminary and promising evidence on the benefits of CBT/WBT in treating demoralization in ACS patients. Moreover, ACS patients with somatization or positive history of depression could be at higher risk for developing persistent demoralization.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100444"},"PeriodicalIF":8.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000097/pdfft?md5=33746a11bb22b3fb6271281d60737465&pid=1-s2.0-S1697260024000097-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139586431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chun Xie , Brandon L. Alderman , Fanying Meng , Ying-Chu Chen , Yu-Kai Chang , Kun Wang
{"title":"Acute high-intensity interval exercise improves food-related cognition in young adults with obesity: An ERP study","authors":"Chun Xie , Brandon L. Alderman , Fanying Meng , Ying-Chu Chen , Yu-Kai Chang , Kun Wang","doi":"10.1016/j.ijchp.2023.100430","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100430","url":null,"abstract":"<div><p><em>Purpose</em> Cognitive function, particularly food-related cognition, is critical for maintaining a healthy weight and preventing the acceleration of obesity. High-Intensity Interval Exercise (HIIE) is an increasingly popular form of exercise and has been shown to improve physical fitness and cognitive function. However, there is limited research on the effects and underlying mechanisms of HIIE on general and food-related cognition among adults with obesity. The aim of the current study was to examine the influence of a single bout of HIIE on food-related cognition among young adults with obesity.</p><p><em>Methods</em> Fifteen young men with obesity (BMI = 33.88 ± 4.22, age = 24.60 ± 5.29 years) were recruited. Participants took part in a HIIE condition consisting of 30 minutes of stationary cycle exercise (5-min warm-up, 20-min HIIE and 5-min cool down), and a control session consisting of a time and attention-matched period of sedentary rest in a counterbalanced order. Behavioral (reaction time and accuracy) and event-related potential measures (P3 and the late positive potential, LPP) elicited during a food-related Flanker task were measured after the HIIE and control session.</p><p><em>Results</em> Shorter response times were observed following HIIE, regardless of congruency or picture type, with no change in accuracy. Increased P3 and LPP amplitudes were observed following HIIE relative to the control session.</p><p><em>Conclusion</em> The findings suggest a single bout of HIIE has a beneficial effect on general and food-related cognition among young adults with obesity, with increased recruitment of cognitive resources to support cognitive control. Future research is warranted to examine the dose-response relationship between acute bouts or longer participation in HIIE on food-related cognition in obesity.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100430"},"PeriodicalIF":8.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000662/pdfft?md5=73e9be8e6aa0bc4089f6f70bb35542f3&pid=1-s2.0-S1697260023000662-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138839769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leila Azari , Homa Hemati , Ronia Tavasolian , Sareh Shahdab , Stephanie M. Tomlinson , Margarita Bobonis Babilonia , Jeffrey Huang , Danielle B. Tometich , Kea Turner , Heather S.L. Jim , Amir Alishahi Tabriz
{"title":"The efficacy and safety of ketamine for depression in patients with cancer: A systematic review","authors":"Leila Azari , Homa Hemati , Ronia Tavasolian , Sareh Shahdab , Stephanie M. Tomlinson , Margarita Bobonis Babilonia , Jeffrey Huang , Danielle B. Tometich , Kea Turner , Heather S.L. Jim , Amir Alishahi Tabriz","doi":"10.1016/j.ijchp.2023.100428","DOIUrl":"https://doi.org/10.1016/j.ijchp.2023.100428","url":null,"abstract":"<div><h3>Background</h3><p>Management of depression in the oncology population includes supportive psychotherapeutic interventions with or without psychotropic medication, which take time to demonstrate effectiveness. Fast-acting interventions, like ketamine, can provide a rapid antidepressant effect; however, there has been limited research on effects of ketamine among cancer patients. The objective of this review is to provide an overview of research on the efficacy and safety of ketamine on depression in patients with cancer.</p></div><div><h3>Methods</h3><p>We reviewed the published literature in MEDLINE® (via PubMed®), EMBASE, and Scopus from 1 January 1982 to 20 October 2022. We screened the retrieved abstracts against inclusion criteria and conducted a full‐text review of eligible studies. Following extraction of data from included studies, we used a framework analysis approach to summarize the evidence on using ketamine in patients with cancer.</p></div><div><h3>Results</h3><p>All 5 included studies were randomized clinical trials conducted in inpatient settings in China. In all included studies ketamine was administered intravenously. Three studies used only racemic ketamine, and two studies used both S-ketamine and racemic ketamine. All included studies reported ketamine a tolerable and effective drug to control depression symptoms.</p></div><div><h3>Conclusion</h3><p>Included studies showed administration of sub-anesthesia ketamine significantly improves postoperative depression among patients with cancer.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100428"},"PeriodicalIF":8.8,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000649/pdfft?md5=7e35195763b03243e7ff32b64c9c5e8d&pid=1-s2.0-S1697260023000649-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138713396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Schwendinger , V.N. Looser , M. Gerber , A. Schmidt-Trucksäss
{"title":"Autonomic dysfunction and exercise intolerance in post-COVID-19 - An as yet underestimated organ system?","authors":"F. Schwendinger , V.N. Looser , M. Gerber , A. Schmidt-Trucksäss","doi":"10.1016/j.ijchp.2023.100429","DOIUrl":"10.1016/j.ijchp.2023.100429","url":null,"abstract":"<div><p>Individuals recovering from COVID-19 often present with persistent symptoms, particularly exercise intolerance and low cardiorespiratory fitness. Put simply, the Wasserman gear system describes the interdependence of heart, lungs, and musculature as determinants of cardiorespiratory fitness. Based on this system, recent findings indicate a contribution of peripheral, cardiovascular, and lung diffusion limitations to persistent symptoms of exercise intolerance and low cardiorespiratory fitness. The autonomic nervous system as an organ system involved in the pathophysiology of exercise intolerance and low cardiorespiratory fitness, has received only little attention as of yet. Hence, our article discusses contribution of the autonomic nervous system through four potential pathways, namely alterations in (1) cerebral hemodynamics, (2) afferent and efferent signaling, (3) central hypersensitivity, and (4) appraisal and engagement in physical activity. These pathways are summarized in a psycho-pathophysiological model. Consequently, this article encourages a shift in perspective by examining the state of the pulmonary and cardiovascular system, the periphery, and auxiliary, the autonomic nervous system as potential underlying mechanisms for exercise intolerance and low cardiorespiratory fitness in patients with post-COVID-19.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100429"},"PeriodicalIF":8.8,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000650/pdfft?md5=89e010ce0a5faa5b2bf8bf2427bf08f6&pid=1-s2.0-S1697260023000650-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138627746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoqi Song , Lijing Niu , Roee Admon , Jixin Long , Qian Li , Lanxin Peng , Tatia M.C. Lee , Ruibin Zhang
{"title":"Aberrant positive affect dynamics in individuals with subthreshold depression: Evidence from laboratory and real-world assessments","authors":"Xiaoqi Song , Lijing Niu , Roee Admon , Jixin Long , Qian Li , Lanxin Peng , Tatia M.C. Lee , Ruibin Zhang","doi":"10.1016/j.ijchp.2023.100427","DOIUrl":"10.1016/j.ijchp.2023.100427","url":null,"abstract":"<div><h3>Background/Objective</h3><p>Reduced positive affect (PA) is a core feature of major depressive disorder (MDD). However, the precursor of MDD, subthreshold depression (StD), has received less attention in this regard. Therefore, we examined PA dynamics in StD, integrating laboratory-based and ecological momentary assessment (EMA) approaches.</p></div><div><h3>Method</h3><p>Participants were college students recruited from Chinese universities (31 with StD, and 39 healthy controls (HC)). Positive mood was induced in the laboratory by an eight-minute comedy clip used to assess PA reactivity and maintenance. To extend findings to the real world and explore mechanisms of PA maintenance, 53 participants with StD and 64 HC reported their emotional states 14 times daily for one week via EMA. Multilevel models were used to test for predictors of PA inertia.</p></div><div><h3>Results</h3><p>In the laboratory, participants with StD achieved the same PA reactivity as HC when facing positive stimuli, yet the curve-fitting revealed difficulties for the StD group in maintaining PA over time. Such reduced capacity was further observed in real-world settings, manifesting in significantly greater PA inertia.</p></div><div><h3>Conclusions</h3><p>High PA inertia in daily life may reflect resistance to mood change in StD, explaining anhedonia and difficulties with emotional maintenance, and highlighting the need for early identification.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 1","pages":"Article 100427"},"PeriodicalIF":8.8,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260023000637/pdfft?md5=c2b0283abfcc1cc073121347db8b5cbe&pid=1-s2.0-S1697260023000637-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138627905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}