Kerem Böge , Niklas Bergmann , Marco Zierhut , Inge Hahne , Alice Braun , Julia Kraft , Ingmar Conell , Thi Minh Tam Ta , Neil Thomas , Paul Chadwick , Stephan Ripke , Eric Hahn
{"title":"The relationship between mindfulness and empathy with the oxytocinergic system in persons with schizophrenia spectrum disorders – A proof-of-concept randomized controlled trial (OXYGEN)","authors":"Kerem Böge , Niklas Bergmann , Marco Zierhut , Inge Hahne , Alice Braun , Julia Kraft , Ingmar Conell , Thi Minh Tam Ta , Neil Thomas , Paul Chadwick , Stephan Ripke , Eric Hahn","doi":"10.1016/j.ijchp.2024.100503","DOIUrl":"10.1016/j.ijchp.2024.100503","url":null,"abstract":"<div><h3>Background</h3><p>The present study explored the feasibility and acceptability as well as the impact of mindfulness-based group therapy (MBGT) on oxytocin levels (OXT) and clinical parameters in outpatients with schizophrenia spectrum disorders (SSD).</p></div><div><h3>Methods</h3><p>In a randomized-controlled design, outpatients with SSD (<em>N</em> = 48) were assigned to either MBGT in addition to German university-level treatment as usual (MBGT+TAU; <em>n</em> = 25) or TAU (<em>n</em> = 23). At baseline and at four-week post-intervention, clinical parameters and OXT levels were determined.</p></div><div><h3>Results</h3><p>Results indicate high feasibility and acceptance with a 95.7% adherence- and 94% retention- rate of MBGT in SSD. While no significant changes in empathy were observed, MBGT+TAU demonstrated a significant reduction in positive symptoms (Positive and Negative Syndrom Scale) compared to TAU at post-intervention. OXT levels were significantly increased in MBGT+TAU at post-intervention, suggesting a potential link between mindfulness and the oxytocinergic system in SSD. Additionally, improvements in various clinical parameters were indicated.</p></div><div><h3>Conclusion</h3><p>The study contributes to the growing evidence supporting feasibility, acceptability, and positive effects of MBGT in outpatients with SSD, emphasizing the need for further research to solidify these findings. Overall, this work sheds first evidence on the intersection of mindfulness, oxytocin, and clinical outcomes in SSD.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100503"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000681/pdfft?md5=cc42d6ec8f6df7bb7e6b764aa6cb9b34&pid=1-s2.0-S1697260024000681-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qian Yu , Zhaowei Kong , Liye Zou , Fabian Herold , Sebastian Ludyga , Zhihao Zhang , Meijun Hou , Arthur F. Kramer , Kirk I. Erickson , Marco Taubert , Charles H. Hillman , Sean P. Mullen , Markus Gerber , Notger G. Müller , Keita Kamijo , Toru Ishihara , Robert Schinke , Boris Cheval , Terry McMorris , Ka Kit Wong , Jinlei Nie
{"title":"Imaging body-mind crosstalk in young adults","authors":"Qian Yu , Zhaowei Kong , Liye Zou , Fabian Herold , Sebastian Ludyga , Zhihao Zhang , Meijun Hou , Arthur F. Kramer , Kirk I. Erickson , Marco Taubert , Charles H. Hillman , Sean P. Mullen , Markus Gerber , Notger G. Müller , Keita Kamijo , Toru Ishihara , Robert Schinke , Boris Cheval , Terry McMorris , Ka Kit Wong , Jinlei Nie","doi":"10.1016/j.ijchp.2024.100498","DOIUrl":"10.1016/j.ijchp.2024.100498","url":null,"abstract":"<div><h3>Objective</h3><p>There is evidence that complex relationships exist between motor functions, brain structure, and cognitive functions, particularly in the aging population. However, whether such relationships observed in older adults could extend to other age groups (e.g., younger adults) remains to be elucidated. Thus, the current study addressed this gap in the literature by investigating potential associations between motor functions, brain structure, and cognitive functions in a large cohort of young adults</p></div><div><h3>Methods</h3><p>In the current study, data from 910 participants (22–35 yr) were retrieved from the Human Connectome Project. Interactions between motor functions (i.e., cardiorespiratory fitness, gait speed, hand dexterity, and handgrip strength), brain structure (i.e., cortical thickness, surface area, and subcortical volumes), and cognitive functions were examined using linear mixed-effects models and mediation analyses. The performance of different machine-learning classifiers to discriminate young adults at three different levels (related to each motor function) was compared</p></div><div><h3>Results</h3><p>Cardiorespiratory fitness and hand dexterity were positively associated with fluid and crystallized intelligence in young adults, whereas gait speed and handgrip strength were correlated with specific measures of fluid intelligence (e.g., inhibitory control, flexibility, sustained attention, and spatial orientation; false discovery rate [FDR] corrected, <em>p</em> < 0.05). The relationships between cardiorespiratory fitness and domains of cognitive function were mediated by surface area and cortical volume in regions involved in the default mode, sensorimotor, and limbic networks (FDR corrected, <em>p</em> < 0.05). Associations between handgrip strength and fluid intelligence were mediated by surface area and volume in regions involved in the salience and limbic networks (FDR corrected, <em>p</em> < 0.05). Four machine-learning classifiers with feature importance ranking were built to discriminate young adults with different levels of cardiorespiratory fitness (random forest), gait speed, hand dexterity (support vector machine with the radial kernel), and handgrip strength (artificial neural network)</p></div><div><h3>Conclusions</h3><p>In summary, similar to observations in older adults, the current study provides empirical evidence (i) that motor functions in young adults are positively related to specific measures of cognitive functions, and (ii) that such relationships are at least partially mediated by distinct brain structures. Furthermore, our analyses suggest that machine-learning classifier has a promising potential to be used as a classification tool and decision support for identifying populations with below-average motor and cognitive functions.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100498"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000632/pdfft?md5=11c5ba011bb91c6df429f8c2824da402&pid=1-s2.0-S1697260024000632-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuai Wang , Xiao Luo , Xinlei Zang , Yiqing Ma , Juan Yang
{"title":"Impact of social reward on stress circuit function and regulation: Path differences between value affirmation and emotional support","authors":"Shuai Wang , Xiao Luo , Xinlei Zang , Yiqing Ma , Juan Yang","doi":"10.1016/j.ijchp.2024.100499","DOIUrl":"10.1016/j.ijchp.2024.100499","url":null,"abstract":"<div><h3>Background</h3><p>As two typical types of social rewards, both value affirmation and emotional support could alleviate acute stress response, but it is not clear whether they can impact stress circuit function and regulation through different neural pathways.</p></div><div><h3>Method</h3><p>Sixty-two participants were randomly assigned to the value affirmation, emotional support, and non-reward conditions, then administered an adapted version of the ScanSTRESS paradigm. Participants’ subjective reports of uncontrollability and social evaluative threat were measured to explore the mitigation of stress by social rewards at the behavioral level. Meanwhile, their acute salivary cortisol response to stress was compared among different social reward conditions. Furthermore, we computed linear contrasts for performance (vs relaxation) and reward (vs non-reward) and used psychophysiological interaction (PPI) analysis to explore the impact of social reward on stress circuit function and regulation.</p></div><div><h3>Results</h3><p>Both value affirmation and emotional support conditions reduced subjective reports of uncontrollability and social evaluation threat, but not cortisol response to stress. Furthermore, value affirmation reduced uncontrollability by enhancing putamen activation, whereas emotional support reduced social evaluation threat by enhancing putamen activation. More importantly, during stress, value affirmation enhanced the functional connectivity of the putamen-hippocampus and putamen-angular gyrus (AG), whereas emotional support enhanced the functional connectivity of the putamen-ventrolateral prefrontal cortex (vlPFC) and putamen-temporal pole mid, compared to the non-reward condition.</p></div><div><h3>Conclusion</h3><p>Value affirmation and emotional support alleviated acute stress response in different neural pathways. These findings suggested a precise categorization of social reward in intervention of a range of adverse psychological and physiological responses caused by stress.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100499"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000644/pdfft?md5=6b3637344e2ee055db94b72e0c84bde6&pid=1-s2.0-S1697260024000644-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naem Haihambo , Meijia Li , Qianying Ma , Chris Baeken , Natacha Deroost , Kris Baetens , Frank Van Overwalle
{"title":"Exciting the social butterfly: Anodal cerebellar transcranial direct current stimulation modulates neural activation during predictive social mentalizing","authors":"Naem Haihambo , Meijia Li , Qianying Ma , Chris Baeken , Natacha Deroost , Kris Baetens , Frank Van Overwalle","doi":"10.1016/j.ijchp.2024.100480","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100480","url":null,"abstract":"<div><p>Transcranial Direct Current Stimulation (tDCS) has emerged as a promising tool for enhancing social cognition. The posterior cerebellum, which is part of the mentalizing network, has been implicated in social processes. In our combined tDCS-fMRI study, we investigated the effects of offline anodal cerebellar tDCS on activation in the cerebellum during social action prediction. Forty-one participants were randomly assigned to receive either anodal (2 mA) or sham (0 mA) stimulation over the midline of the posterior cerebellum for 20 min. Twenty minutes post stimulation, participants underwent a functional MRI scan to complete a social action prediction task, during which they had to correctly order randomly presented sentences that described either actions of social agents (based on their personality traits) or events of objects (based on their characteristics). As hypothesized, our results revealed that participants who received anodal cerebellar tDCS exhibited increased activation in the posterior cerebellar Crus 2 and lobule IX, and in key cerebral mentalizing areas, including the medial prefrontal cortex, temporo-parietal junction, and precuneus. Contrary to our hypotheses, participants who received anodal stimulation demonstrated faster responses to non-social objects compared to social agents, while sham participants showed no significant differences. We did not find a significant relationship between electric field magnitude, neural activation and behavioral outcomes. These findings suggest that tDCS targeting the posterior cerebellum selectively enhances activation in social mentalizing areas, while only facilitating behavioral performance of non-social material, perhaps because of a ceiling effect due to familiarity with social processing.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100480"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000450/pdfft?md5=6f4850229176cc519b12705cc07e94fc&pid=1-s2.0-S1697260024000450-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junying Yuan , Gailing Wang , Mengyue Li , Lingling Zhang , Longyuan He , Yiran Xu , Dengna Zhu , Zhen Yang , Wending Xin , Erliang Sun , Wei Zhang , Li Li , Xiaoli Zhang , Changlian Zhu
{"title":"Development and validation of a nomogram for predicting intellectual disability in children with cerebral palsy","authors":"Junying Yuan , Gailing Wang , Mengyue Li , Lingling Zhang , Longyuan He , Yiran Xu , Dengna Zhu , Zhen Yang , Wending Xin , Erliang Sun , Wei Zhang , Li Li , Xiaoli Zhang , Changlian Zhu","doi":"10.1016/j.ijchp.2024.100493","DOIUrl":"10.1016/j.ijchp.2024.100493","url":null,"abstract":"<div><h3>Objective</h3><p>Intellectual disability (ID) is a prevalent comorbidity in children with cerebral palsy (CP), presenting significant challenges to individuals, families and society. This study aims to develop a predictive model to assess the risk of ID in children with CP.</p></div><div><h3>Methods</h3><p>We analyzed data from 885 children diagnosed with CP, among whom 377 had ID. Using least absolute shrinkage and selection operator regression, along with univariate and multivariate logistic regression, we identified key predictors for ID. Model performance was evaluated through receiver operating characteristic curves, calibration plots, and decision curve analysis (DCA). Bootstrapping validation was also employed.</p></div><div><h3>Results</h3><p>The predictive nomogram included variables such as preterm birth, CP subtypes, Gross Motor Function Classification System level, MRI classification category, epilepsy status and hearing loss. The model demonstrated strong discrimination with an area under the receiver operating characteristic curve (AUC) of 0.781 (95% CI: 0.7504-0.8116) and a bootstrapped AUC of 0.7624 (95% CI: 0.7216-0.8032). Calibration plots and the Hosmer-Lemeshow test indicated a good fit (χ<sup>2</sup>= 7.9061, p = 0.4427). DCA confirmed the model's clinical utility. The cases were randomly divided into test group and validation group at a 7:3 ratio, demonstrating strong discrimination, good fit and clinical utility; similar results were found when stratified by sex.</p></div><div><h3>Conclusions</h3><p>This predictive model effectively identifies children with CP at a high risk for ID, facilitating early intervention strategies. Stratified risk categories provide precise guidance for clinical management, aiming to optimize outcomes for children with CP by leveraging neuroplasticity during early childhood.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100493"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000589/pdfft?md5=c105257dd6ed4db16a436ee52a523c2f&pid=1-s2.0-S1697260024000589-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The paradox of social avoidance and the yearning for understanding: Elevated interbrain synchrony among socially avoidant individuals during expression of negative emotions","authors":"Xinmei Deng , Xiaomin Chen , Jiao Wang","doi":"10.1016/j.ijchp.2024.100500","DOIUrl":"10.1016/j.ijchp.2024.100500","url":null,"abstract":"<div><p>Social avoidance refers to the tendency to be alone and non-participating to social interactions, which is considered to hamper health interpersonal relationship. However, the neural underpinnings of social and emotional interactions among social avoidant individuals have not been fully studied. In the present study, we used EEG hyperscanning technology to investigate the brain activity and its synchronization of 25 socially avoidant dyads and 28 comparison dyads during an emotional communication task. The emotional communication task consisted of the emotional processing stage and emotional interaction stage. Event-related potentials (ERPs) of the senders during the emotional processing stage and the interbrain synchrony (IBS) of the dyads during the emotional interaction stage were analyzed. Results showed that (1) socially avoidant group showed higher beta, theta and gamma IBS in the negative condition than in the positive and neutral condition; (2) in positive condition, the N1 and LPP amplitudes during the emotional processing stage of socially avoidant individuals were negatively correlated with the IBS within dyads during the emotional communication stage. The findings suggest that the dysfunctional emotional interaction of social avoidant individuals may be attributed to the negative impact of emotional stimuli processing during emotional communication.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100500"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000656/pdfft?md5=2296cf0e662da20aa109ea374b87e17f&pid=1-s2.0-S1697260024000656-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142098177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic academic stress improves attentional control: Behavioral and electrophysiological evidence","authors":"Mingming Qi, Ru Gai, Yuxi Wang, Heming Gao","doi":"10.1016/j.ijchp.2024.100484","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100484","url":null,"abstract":"<div><h3>Background</h3><p>Detecting and responding to target objects in the visual environment is a key factor in goal-directed behavior. Exposure to chronic stress often results in alterations of prefrontal cortex (PFC) function, which may impact PFC-dependent selective attention process. This study aimed to investigate the effect of chronic academic stress on attentional control process.</p></div><div><h3>Method</h3><p>Both the stress group and the control group performed an arrow-based version of the Eriksen Flanker task. Event-related potentials (ERP) were recorded while the participants performed the task.</p></div><div><h3>Results</h3><p>The behavioural results exhibited decreased Flanker RT effect for the stress group compared to the control group, suggesting a reduced interference under stress. The ERP results showed that stress group showed decreased frontal N2 but increased early P3 and late P3/LPC activities compared to the control group. These results suggest reduced conflict monitoring but increased conflict resolution process under stress.</p></div><div><h3>Conclusions</h3><p>The chronic academic stress improves attentional control by reducing the conflict monitoring and enhancing conflict resolution processes.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100484"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000498/pdfft?md5=346888c726c06764656d64356e45c4d0&pid=1-s2.0-S1697260024000498-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141543614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guanmao Chen , Zixuan Guo , Pan Chen , Zibin Yang , Hong Yan , Shilin Sun , Wenhao Ma , Yuan Zhang , Zhangzhang Qi , Wenjie Fang , Lijun Jiang , Qian Tao , Ying Wang
{"title":"Bright light therapy-induced improvements of mood, cognitive functions and cerebellar functional connectivity in subthreshold depression: A randomized controlled trial","authors":"Guanmao Chen , Zixuan Guo , Pan Chen , Zibin Yang , Hong Yan , Shilin Sun , Wenhao Ma , Yuan Zhang , Zhangzhang Qi , Wenjie Fang , Lijun Jiang , Qian Tao , Ying Wang","doi":"10.1016/j.ijchp.2024.100483","DOIUrl":"https://doi.org/10.1016/j.ijchp.2024.100483","url":null,"abstract":"<div><h3>Background</h3><p>The efficacy of bright light therapy (BLT) in ameliorating depression has been validated. The present study is to investigate the changes of depressive symptoms, cognitive function and cerebellar functional connectivity (FC) following BLT in individuals with subthreshold depression (StD).</p></div><div><h3>Method</h3><p>Participants were randomly assigned to BLT group (<em>N</em> = 47) or placebo (<em>N</em> = 41) in this randomized controlled trial between March 2020 and June 2022. Depression severity and cognitive function were assessed, as well as resting-state functional MRI scan was conducted before and after 8-weeks treatment. Seed-based whole-brain static FC (sFC) and dynamic FC (dFC) analyses of the bilateral cerebellar subfields were conducted. Besides, a multivariate regression model examined whether baseline brain FC was associated with changes of depression severity and cognitive function during BLT treatment.</p></div><div><h3>Results</h3><p>After 8-week BLT treatment, individuals with StD showed improved depressive symptoms and attention/vigilance cognitive function. BLT also increased sFC between the right cerebellar lobule IX and left temporal pole, and decreased sFC within the cerebellum, and dFC between the right cerebellar lobule IX and left medial prefrontal cortex. Moreover, the fusion of sFC and dFC at baseline could predict the improvement of attention/vigilance in response to BLT.</p></div><div><h3>Conclusions</h3><p>The current study identified that BLT improved depressive symptoms and attention/vigilance, as well as changed cerebellum-DMN connectivity, especially in the cerebellar-frontotemporal and cerebellar internal FC. In addition, the fusion features of sFC and dFC at pre-treatment could serve as an imaging biomarker for the improvement of attention/vigilance cognitive function after BLT in StD.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100483"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000486/pdfft?md5=787124716898cb45d8f7284ba55a6c6d&pid=1-s2.0-S1697260024000486-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bing Lin , Shihan Feng , Jiaxiu Liu , Kangjie Li , Guiqian Shi , Xiaoni Zhong
{"title":"Using an interactive web application to identify pre-exposure prophylaxis adherence among men who have sex with men","authors":"Bing Lin , Shihan Feng , Jiaxiu Liu , Kangjie Li , Guiqian Shi , Xiaoni Zhong","doi":"10.1016/j.ijchp.2024.100490","DOIUrl":"10.1016/j.ijchp.2024.100490","url":null,"abstract":"<div><h3>Background</h3><p>Men who have sex with men (MSM) are at a high risk for HIV infection. While pre-exposure prophylaxis (PrEP) is an effective oral preventive strategy, its success is largely dependent on consistent medication adherence.</p></div><div><h3>Objective</h3><p>The aim of this study was to develop the machine learning web application and evaluate the performance in predicting PrEP adherence.</p></div><div><h3>Methods</h3><p>The PrEP prospective cohort study of the MSM population conducted in Western China from 2019 to 2023, and we collected adherence data and personal characteristics data from 747 MSM. Predictor variables were screened and the performance of several machine learning methods in predicting nonadherent behaviors were compared.</p></div><div><h3>Results</h3><p>A total of 11 candidate variables were screened that predicted nonadherent behaviors. We developed and evaluated five machine learning models that performed well in predicting adherence. Attitudes of male sexual partners, self-efficacy, HIV testing, number of male sexual partners, and risk perception were the most important predictors of adherence. The optimal prediction model was displayed in a shiny web application for online calculation of the probability of occurrence of nonadherent behaviors among MSM.</p></div><div><h3>Conclusions</h3><p>Machine learning performed well in predicting nonadherent behaviors among MSM. An interactive and intuitive web application can help identify individuals who may have nonadherent behaviors, resulting in improved medication adherence and increased prevention efficacy.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100490"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000553/pdfft?md5=91f8f92cdf511192f75a5b7b2f7380e9&pid=1-s2.0-S1697260024000553-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141941172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giorgio Falgares , Giulia Costanzo , Lilybeth Fontanesi , Maria Cristina Verrocchio , Franco Bin , Daniela Marchetti
{"title":"The role of sexual communication in the relationship between emotion regulation and sexual functioning in women: The impact of age and relationship status","authors":"Giorgio Falgares , Giulia Costanzo , Lilybeth Fontanesi , Maria Cristina Verrocchio , Franco Bin , Daniela Marchetti","doi":"10.1016/j.ijchp.2024.100482","DOIUrl":"10.1016/j.ijchp.2024.100482","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to investigate sexual communication as a mechanism involved in the link between emotion regulation and sexual functioning in a sample of adult women, also testing the moderating role of relationship status and age in this association.</p></div><div><h3>Method</h3><p>1344 sexually active cisgender women (aged 18–57, <em>M</em> = 27.34; SD= 6.484) were recruited from March 30, 2021, to April 12, 2021, through an online survey. From the initial sample, 1280 women were retained and included in the analysis. Participants were asked to respond to three self-report questionnaires: the Difficulties in Emotion Regulation Scale (DERS), the <em>Communication</em> subscale of the Sexual Satisfaction Scale for Women (SSS-W), and the Female Sexual Function Index (FSFI).</p></div><div><h3>Results</h3><p>We found that sexual communication mediated the link between emotion regulation abilities and female sexual functioning. Moreover, we found that age, but not relationship status, moderated the association between emotion regulation and sexual communication, so that older women with difficulties in emotion regulation processes showed worse sexual communication abilities as compared to younger women.</p></div><div><h3>Conclusions</h3><p>According to this study's results, clinicians and sexual therapists should carefully consider emotion regulation abilities and sexual communication as crucial factors in promoting women's sexual well-being.</p></div>","PeriodicalId":47673,"journal":{"name":"International Journal of Clinical and Health Psychology","volume":"24 3","pages":"Article 100482"},"PeriodicalIF":5.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1697260024000474/pdfft?md5=84c96cc92298444027414d81eec7f060&pid=1-s2.0-S1697260024000474-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141575308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}