Journal of Maxillofacial & Oral Surgery最新文献

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Oral Implantology-Current Concepts. 口腔种植-当前的概念。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-07-10 DOI: 10.1007/s12663-025-02684-0
Anjan Kumar Shah
{"title":"Oral Implantology-Current Concepts.","authors":"Anjan Kumar Shah","doi":"10.1007/s12663-025-02684-0","DOIUrl":"https://doi.org/10.1007/s12663-025-02684-0","url":null,"abstract":"<p><p>Dental implants have become a mainstream way of treating edentulism. The editorial discusses the progress in this field and gives an overview of the list of articles in this special edition.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"853-854"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orbital-Zygomatic-Maxillary Mucormycosis: Does the Aesthetic Influence on Treatment Guidelines? 眼眶-颧-上颌毛霉菌病:审美对治疗指南有影响吗?
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-04-16 DOI: 10.1007/s12663-025-02511-6
Bruna Campos Ribeiro, Priscila Faleiros Bertelli Trivellato, Cassio Edvard Sverzut, Alexandre Elias Trivellato
{"title":"Orbital-Zygomatic-Maxillary Mucormycosis: Does the Aesthetic Influence on Treatment Guidelines?","authors":"Bruna Campos Ribeiro, Priscila Faleiros Bertelli Trivellato, Cassio Edvard Sverzut, Alexandre Elias Trivellato","doi":"10.1007/s12663-025-02511-6","DOIUrl":"https://doi.org/10.1007/s12663-025-02511-6","url":null,"abstract":"<p><strong>Study design: </strong>This is a two-part study, involving a cross-sectional retrospective analysis based on data collection, and a broad literature review.</p><p><strong>Objective: </strong>To provide a statement and guideline for treating orbitozygomatic-maxillary mucormycosis focusing on the patient's facial aesthetic and function.</p><p><strong>Methods: </strong>The cross-sectional stage enrolled patients with confirmed mucormycosis on the face, recorded through written medical records. The literature review employed a comprehensive search strategy to identify relevant articles.</p><p><strong>Results: </strong>Immediate reconstruction was found to positively influence the patient's aesthetics and function.</p><p><strong>Conclusion: </strong>This study highlights the importance of immediate reconstruction for patients with orbitozygomatic-maxillary mucormycosis, as it positively impacts the patient's facial aesthetics and function. Surgical planning was based on the size and complexity of the defect and the patient's facial aesthetics. The treatment should be carried out following each patient's clinical course, focusing on the control of the adjacent immunosuppression.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1195-1201"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Specific Implants in Maxillo-Facial Reconstruction: Current Practices and Way Forward-An Overview of Systematic Reviews. 患者特异性种植体在上颌面部重建:目前的做法和前进的道路-系统综述。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-01-15 DOI: 10.1007/s12663-025-02440-4
Vivekanand Kattimani, Roopa Rani Sreeram, Gnana Sarita Kumari Panga, Divya Bhavani Vasamsetti, Rahul Tiwari
{"title":"Patient-Specific Implants in Maxillo-Facial Reconstruction: Current Practices and Way Forward-An Overview of Systematic Reviews.","authors":"Vivekanand Kattimani, Roopa Rani Sreeram, Gnana Sarita Kumari Panga, Divya Bhavani Vasamsetti, Rahul Tiwari","doi":"10.1007/s12663-025-02440-4","DOIUrl":"https://doi.org/10.1007/s12663-025-02440-4","url":null,"abstract":"<p><strong>Background: </strong>Maxillofacial reconstruction has undergone a paradigm shift from conventional to digital workflows. The integration of Three Dimensional (3D) technology and patient-specific implants (PSIs) has revolutionized surgical planning and execution, particularly in complex procedures. This overview of systematic review (SR) aims to provide healthcare professionals with a comprehensive, evidence-based resource on current practices and future perspectives of maxillofacial reconstruction using 3D technology and PSIs.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted from inception 30th September 2023, using keywords such as \"3D printing,\" \"patient-specific implants,\" \"maxillofacial reconstruction,\" and related terms. The search included PubMed, ScienceDirect, and Cochrane databases. Only SRs focusing on maxillofacial reconstruction with 3D technology were included. Article quality was assessed using the AMSTAR (A MeaSurement Tool to Assess systematic Reviews) tool and Glenny et al. checklists.</p><p><strong>Results: </strong>Out of 327 search results, fourteen articles met the inclusion criteria. Most reviews focused on reconstructing orbital, nasal, maxillary, mandibular, and temporomandibular joint defects. Notably, only one Cochrane review was identified, indicating a lack of high-quality randomized or cohort studies. Furthermore, only three reviews had a registered protocol.</p><p><strong>Conclusion: </strong>While the literature supports the use of PSIs and 3D technology in maxillofacial reconstruction, the evidence quality remains moderate to poor. The heterogeneity of the data across studies has limited the ability to perform a meta-analysis. SRs emphasize the need for careful ethical considerations when using medical devices like PSIs. Although advanced technologies enhance surgical outcomes, they come with a steep learning curve and require rigorous clinical validation.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1075-1089"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Clinical and Radiographic Changes Between Immediate Loading Versus Delayed Loading of Dental Implants. 即刻加载与延迟加载牙种植体临床与影像学变化的比较评价。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-14 DOI: 10.1007/s12663-025-02495-3
Amanjyot Kaur Bains, Amit Dhawan, Tejinder Kaur Gumber, Ramandeep Singh Bhullar, Sarika Kapila
{"title":"Comparative Evaluation of Clinical and Radiographic Changes Between Immediate Loading Versus Delayed Loading of Dental Implants.","authors":"Amanjyot Kaur Bains, Amit Dhawan, Tejinder Kaur Gumber, Ramandeep Singh Bhullar, Sarika Kapila","doi":"10.1007/s12663-025-02495-3","DOIUrl":"https://doi.org/10.1007/s12663-025-02495-3","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present study is to compare the marginal bone level changes and implant survival rate between immediately loaded non-submerged versus delayed loaded submerged dental implants.</p><p><strong>Materials and methods: </strong>The implant sites of 20 patients were divided into two groups-Group A (implant placement was done by immediate loading protocol) and Group B patients (implant placement was done by conventional delayed loading protocol). Clinical parameters that were recorded include implant stability, radiographic assessment for crestal bone changes, gingival status, probing depth, and complications. The data were statistically analyzed by one-way ANOVA, <i>t</i> test, and chi-square test (<i>p</i> < 0.05).</p><p><strong>Results: </strong>On intergroup comparison, gingival status was more maintained in the case of the immediate loading group, while there was no statistically significant difference in implant stability and marginal bone loss. Complications were reported in both groups but were statistically insignificant in comparison between groups.</p><p><strong>Conclusion: </strong>Immediate loading is a viable treatment modality and can lead to satisfactory clinical and aesthetic outcomes. The provision of an immediate restoration may lead to improved aesthetic outcomes as evidenced by gingival status evaluation when compared to delayed loading.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"952-961"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implants with or without Leukocyte- and Platelet-Rich Fibrin (L-PRF): A Systematic Review on Dental Implant Stability. 植入或不植入富含白细胞和血小板的纤维蛋白(L-PRF):牙科种植体稳定性的系统综述。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-02-19 DOI: 10.1007/s12663-025-02478-4
Mohammadamin Damsaz, Fatemeh Rahmani, Sarah Arzani, Sepideh Jafari, Pegah Farzanegan, Mohammad Hosein Amirzade-Iranaq, Seied Omid Keyhan
{"title":"Implants with or without Leukocyte- and Platelet-Rich Fibrin (L-PRF): A Systematic Review on Dental Implant Stability.","authors":"Mohammadamin Damsaz, Fatemeh Rahmani, Sarah Arzani, Sepideh Jafari, Pegah Farzanegan, Mohammad Hosein Amirzade-Iranaq, Seied Omid Keyhan","doi":"10.1007/s12663-025-02478-4","DOIUrl":"https://doi.org/10.1007/s12663-025-02478-4","url":null,"abstract":"<p><strong>Background: </strong>To examine the impact of applying leukocyte- and platelet-rich fibrin (L-PRF) on the stability of dental implants using implant stability quotient (ISQ) measurements.</p><p><strong>Methods: </strong>A systematic search of the main databases was conducted to source the literature. Studies that met the established inclusion and exclusion criteria were selected for this review. The focus was solely on randomized controlled trials (RCTs) and controlled clinical trials (CCTs).</p><p><strong>Results: </strong>After conducting a comprehensive search, a total of 1984 studies were identified. Following evaluation based on our inclusion and exclusion criteria, a refined selection of 7 studies was chosen for detailed review in this analysis.</p><p><strong>Conclusions: </strong>Our findings indicate that the use of leukocyte- and platelet-rich fibrin (L-PRF) may enhance the stability of implants following surgical procedures. This suggests that L-PRF may accelerate the healing process, reduce the loading time, and improve outcomes for patients undergoing implant surgery, potentially reducing the risk of implant failures and complications.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"914-928"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidisciplinary Management of Aggressive Giant Cell Tumour of the Mandible Using Denosumab, Virtual Surgical Planning, and Patient-Specific Implants: A Case Report with Myasthenia Gravis Considerations. 使用Denosumab、虚拟手术计划和患者特异性植入物对下颌骨侵袭性巨细胞瘤的多学科治疗:一例重症肌无力病例报告
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-21 DOI: 10.1007/s12663-025-02655-5
Raghav S Moorthy, Kannan Balaraman, Sunilkumar Thangaraju, Vimalambiga Ramani, Keerthana R Bhat, Hari Venkatramani, Raja Sabapathy Shanmuganathan
{"title":"Multidisciplinary Management of Aggressive Giant Cell Tumour of the Mandible Using Denosumab, Virtual Surgical Planning, and Patient-Specific Implants: A Case Report with Myasthenia Gravis Considerations.","authors":"Raghav S Moorthy, Kannan Balaraman, Sunilkumar Thangaraju, Vimalambiga Ramani, Keerthana R Bhat, Hari Venkatramani, Raja Sabapathy Shanmuganathan","doi":"10.1007/s12663-025-02655-5","DOIUrl":"https://doi.org/10.1007/s12663-025-02655-5","url":null,"abstract":"<p><strong>Introduction: </strong>This report describes the management of an aggressive mandibular giant cell tumour (GCT) in a 59-year-old male with comorbid myasthenia gravis (MG).</p><p><strong>Case report: </strong>A multidisciplinary approach incorporating neoadjuvant Denosumab, virtual surgical planning, and patient-specific implants enabled precise tumour resection and reconstruction while minimising anaesthesia-related risks.</p><p><strong>Results and conclusion: </strong>The use of advanced techniques significantly reduced surgical time and enhanced functional and aesthetic outcomes. This case highlights the feasibility and effectiveness of integrating modern chemotherapeutics and digital technologies in surgically managing complex maxillofacial tumours, particularly in patients with high perioperative risk due to systemic conditions like MG.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1208-1211"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surface Characteristics and Their Influence on Osseointegration: A Scientometric Analysis with a Focus on Dental Implants. 表面特征及其对骨整合的影响:以牙种植体为中心的科学计量学分析。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-03-25 DOI: 10.1007/s12663-025-02519-y
Mayank Mathur, Peeyush Phogat, Mukesh Jewariya, Meher Wan
{"title":"Surface Characteristics and Their Influence on Osseointegration: A Scientometric Analysis with a Focus on Dental Implants.","authors":"Mayank Mathur, Peeyush Phogat, Mukesh Jewariya, Meher Wan","doi":"10.1007/s12663-025-02519-y","DOIUrl":"https://doi.org/10.1007/s12663-025-02519-y","url":null,"abstract":"<p><strong>Background: </strong>Surface roughness is a critical factor in implant technology, influencing osseointegration and biocompatibility. A thorough understanding of the research landscape is essential to track advancements, key contributors, and highlight emerging trends.</p><p><strong>Objective: </strong>To perform a scientometric analysis of research on surface roughness in implants, identifying trends, highly contributing institutions, collaboration networks, and emerging research areas.</p><p><strong>Methods: </strong>Data was collected from the Web of Science Core Collection using a structured search strategy focused on surface roughness and implant-related terms. Bibliometric techniques, including citation analysis, keyword co-occurrence mapping, and collaboration network visualization, were employed to analyze the dataset.</p><p><strong>Results: </strong>The analysis identified leading institutions, and highly cited publications in the field. Keyword trends indicated growing interest in 3D printing, novel biomaterials, and advanced surface modification techniques. Collaboration networks highlighted interdisciplinary engagement.</p><p><strong>Conclusion: </strong>While significant advancements have been made in understanding surface roughness in implant technology, future research should focus on long-term effects and standardized roughness parameters. Emerging technologies, such as additive manufacturing and bioengineered surfaces, present promising avenues for further innovation.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"899-913"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Customised Patient-Specific Implants in Maxillofacial Reconstruction After Mucormycosis: A Case Series. 毛霉菌病后颌面部重建的定制患者特异性种植体:一个案例系列。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-07-06 DOI: 10.1007/s12663-025-02656-4
M R Haranadha Reddy, Lavanya Ummadisingh, Sarah Fatima
{"title":"Customised Patient-Specific Implants in Maxillofacial Reconstruction After Mucormycosis: A Case Series.","authors":"M R Haranadha Reddy, Lavanya Ummadisingh, Sarah Fatima","doi":"10.1007/s12663-025-02656-4","DOIUrl":"https://doi.org/10.1007/s12663-025-02656-4","url":null,"abstract":"<p><strong>Introduction: </strong>Patient-specific implants(psi) manufactured using 3D printing and CAD-CAM technology have played a major role in the rehabilitation of complex maxillofacial defects caused due to mucormycosis also known as the black fungus, which is a rare fungal infection that originates as a result of inhalation of its filamentous hyphal form.</p><p><strong>Methods: </strong>In this unique case series, we report six cases of complex maxillofacial defects caused due to mucormycosis managed by patient-specific implants, in Hyderabad. These patients had undergone either partial or total maxillectomy after being affected by mucormycosis and were disease-free clinically and radiographically for 6 or more months post-resection and were rehabilitated using patient-specific zygoma implants. All the implants and designs were standardized to achieve optimal functionality. The dental implant component was integrated into the PSI to achieve immediate postoperative dental rehabilitation.</p><p><strong>Conclusion: </strong>This case series shows a new era of reconstruction other than the old standardised method of using allografts for reconstruction in the maxillofacial region.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1115-1121"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Combination of Intralesional Pentoxifylline and Dexamethasone with Intralesional Pentoxifylline, Intralesional Dexamethasone alone in the Treatment of Oral Submucous Fibrosis- A Pilot Study. 局部注射己酮可可碱和地塞米松与局部注射己酮可可碱、局部注射地塞米松联合治疗口腔黏膜下纤维化的疗效初步研究。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-24 DOI: 10.1007/s12663-025-02566-5
Seema Dengra, Nitin Bhola
{"title":"Efficacy of Combination of Intralesional Pentoxifylline and Dexamethasone with Intralesional Pentoxifylline, Intralesional Dexamethasone alone in the Treatment of Oral Submucous Fibrosis- A Pilot Study.","authors":"Seema Dengra, Nitin Bhola","doi":"10.1007/s12663-025-02566-5","DOIUrl":"https://doi.org/10.1007/s12663-025-02566-5","url":null,"abstract":"<p><strong>Background: </strong>Oral submucous fibrosis (OSMF) is a debilitating oral disease, causing progressive loss of vascularity in the diseased mucosa, resulting in epithelial atrophy. Therefore, this pilot study aimed to use intralesional pentoxifylline to increase blood supply to the local tissues, helping in eliminating or reducing the severity of OSMF.</p><p><strong>Aims and objectives: </strong>To comparatively evaluate the effectiveness of the combination of intralesional pentoxifylline and dexamethasone with pentoxifylline and dexamethasone alone in assessing the mouth opening, burning sensation, and USG parameters. The USG parameters included submucosal thickness, echoicity, and blood vascularity. The pilot study results were compared among the three study groups, in terms of increase in mouth opening, reduction in burning sensation, and the above-mentioned USG parameters.</p><p><strong>Methods: </strong>Patients were categorized randomly into Group I (n = 05), Group II (n = 05), and Group III (n = 05): Group I, intralesional dexamethasone 4 mg/ml, Group II, Intralesional PTX 1 mg/ml, while in Group III, combination of both drugs was administered, biweekly for 3 months along with active physiotherapy. Ultrasonography and colour Doppler were done pre- and post-treatment.</p><p><strong>Results: </strong>The increase in mouth opening in Group III was 115%, and in Group II that was 63.46% as compared to Group I 19.28% after 26th dose. The results of various parameters considered in this study were overall better in combination group as compared to other two groups.</p><p><strong>Conclusion: </strong>This regimen will improve quality of life, function, and patient compliance along with down staging of Grade of OSMF.<b>Trial registration number:</b> CTRI/ 2020/09/027836.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1186-1194"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mandibular Defect Reconstruction Using Tissue Engineering: Case Report and Long-Term Follow-Up. 组织工程修复下颌骨缺损:1例报告及长期随访。
IF 0.6
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-08-01 Epub Date: 2025-06-22 DOI: 10.1007/s12663-025-02624-y
Rodrigo Fariña, Jorge Lolas, Emilio Moreno, Felipe Soto, Pablo Romero-Araya
{"title":"Mandibular Defect Reconstruction Using Tissue Engineering: Case Report and Long-Term Follow-Up.","authors":"Rodrigo Fariña, Jorge Lolas, Emilio Moreno, Felipe Soto, Pablo Romero-Araya","doi":"10.1007/s12663-025-02624-y","DOIUrl":"https://doi.org/10.1007/s12663-025-02624-y","url":null,"abstract":"<p><p>Tissue engineering is a new alternative for the treatment of severe mandibular defects, due to its low morbidity and predictability. Specifically, the use of adipose-derived stem cells (ADSc) combined with ceramic substitute like β-TCP. A male patient comes private clinic of Rodrigo Fariña, due to slow-growing and asymptomatic right facial asymmetry. The CT shows a unilocular radiolucent area of 6 cm in its longest axis with defined borders causing rizalysis of adjacent teeth in the right mandibular body. Histopathological examination after incisional biopsy, it´s diagnoses was plexiform unicystic ameloblastoma. Prior to surgical intervention, abdominal adipose tissue was collected for culture with osteoinductive media, in this case ascorbic acid and dexamethasone co-cultivated with blocks of β-TCP. One months later, the mandibular segmental resection with a safety edge is performed where, in the same surgical act, the combination of ADSc and the β-TCP is placed on a titanium mesh at the resection site. Six months later, a biopsy is performed that corroborates the bone neoformation where it is decided to carry out dental rehabilitation on osseointegrated implants. The combination of biomaterials in conjunction with ADSc allows an effective therapy, with a good prognosis for the treatment of severe mandibular defects caused by benign neoplasms.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 4","pages":"1125-1133"},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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