Raghav S Moorthy, Kannan Balaraman, Sunilkumar Thangaraju, Vimalambiga Ramani, Keerthana R Bhat, Hari Venkatramani, Raja Sabapathy Shanmuganathan
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Multidisciplinary Management of Aggressive Giant Cell Tumour of the Mandible Using Denosumab, Virtual Surgical Planning, and Patient-Specific Implants: A Case Report with Myasthenia Gravis Considerations.
Introduction: This report describes the management of an aggressive mandibular giant cell tumour (GCT) in a 59-year-old male with comorbid myasthenia gravis (MG).
Case report: A multidisciplinary approach incorporating neoadjuvant Denosumab, virtual surgical planning, and patient-specific implants enabled precise tumour resection and reconstruction while minimising anaesthesia-related risks.
Results and conclusion: The use of advanced techniques significantly reduced surgical time and enhanced functional and aesthetic outcomes. This case highlights the feasibility and effectiveness of integrating modern chemotherapeutics and digital technologies in surgically managing complex maxillofacial tumours, particularly in patients with high perioperative risk due to systemic conditions like MG.
期刊介绍：
This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.
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