Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_199_26
Ana Luis Correia, Tito A Abrantes, Joana M Correia, Mariana S Conceição
{"title":"When the lung reaches the eye: Ocular metastasis from large-cell neuroendocrine carcinoma.","authors":"Ana Luis Correia, Tito A Abrantes, Joana M Correia, Mariana S Conceição","doi":"10.4103/lungindia.lungindia_199_26","DOIUrl":"10.4103/lungindia.lungindia_199_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"474-476"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of blood eosinophilia and its impact on lung functions in stable chronic obstructive pulmonary disease patients.","authors":"Gursimran Singh, Komaldeep Kaur, Deepak Aggarwal, Anshu Palta, Chahat Bhatia, Varinder Saini","doi":"10.4103/lungindia.lungindia_652_24","DOIUrl":"10.4103/lungindia.lungindia_652_24","url":null,"abstract":"<p><strong>Background and objective: </strong>Chronic obstructive pulmonary disease (COPD) is marked by persistent airflow limitation. Blood eosinophilia has emerged as a potential biomarker for predicting the risk of exacerbations as well as response to inhaled corticosteroids (ICS). However, its impact on lung function in stable COPD remains uncertain. This study aimed to assess the prevalence of blood eosinophilia in stable COPD patients and explore its relationship with lung function, exercise capacity and exacerbation history.</p><p><strong>Methods: </strong>A total of 60 stable COPD patients were included in this cross-sectional study, selected according to specific inclusion and exclusion criteria. Blood eosinophil counts were measured, with eosinophilia defined as ≥2%. Lung function was evaluated through spirometry, while exercise capacity was assessed using the 6-minute walk test (6MWT). Statistical tests were applied to compare data between the eosinophilic and non-eosinophilic groups.</p><p><strong>Results: </strong>Eosinophilia was present in 21.67% of patients. Eosinophilic patients had a higher rate of exacerbations (53.85%) and a lower FEV1 (mean 39.46% predicted) as compared to non-eosinophilic patients (17.02% and 50.79%, respectively). The 6MWT distance was shorter in eosinophilic patients (249.38 meters) as compared to non-eosinophilic patients (274.17 meters).</p><p><strong>Conclusion: </strong>Eosinophilic inflammation in COPD significantly impacts exacerbation risk, lung function and exercise capacity . Eosinophil counts may prove to be a useful biomarker for identifying COPD patients who are more likely to benefit from targeted treatments, such as inhaled corticosteroids (ICS).</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"379-383"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_794_25
Yatin Dholakia
{"title":"Bridging clinical and social gaps in tuberculosis management: A review of India's differentiated TB care framework.","authors":"Yatin Dholakia","doi":"10.4103/lungindia.lungindia_794_25","DOIUrl":"10.4103/lungindia.lungindia_794_25","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"353-356"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_774_25
Simone D Damato, Alessandro S A de Melo, Edson Marchiori
{"title":"Micronodular metastases of melanoma mimicking granulomatous disease.","authors":"Simone D Damato, Alessandro S A de Melo, Edson Marchiori","doi":"10.4103/lungindia.lungindia_774_25","DOIUrl":"10.4103/lungindia.lungindia_774_25","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"469-470"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_230_26
Madhulika L Mahashabde, Sai Karthik Guniganti, Brugumalla V Nitendra Saketh
{"title":"Perfect diagnostic accuracy in a small derivation cohort and outdated classification criteria: Methodological concerns regarding miR-21 as a biomarker for chronic obstructive pulmonary disease-associated pulmonary hypertension.","authors":"Madhulika L Mahashabde, Sai Karthik Guniganti, Brugumalla V Nitendra Saketh","doi":"10.4103/lungindia.lungindia_230_26","DOIUrl":"10.4103/lungindia.lungindia_230_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"481-482"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_225_26
Madhulika L Mahashabde, Sai Karthik Guniganti, Brugumalla V Nitendra Saketh
{"title":"Serogroup characterisation, co-pathogen causality, and environmental surveillance gaps in a cross-sectional study of Legionella pneumophila in hospital-acquired pneumonia.","authors":"Madhulika L Mahashabde, Sai Karthik Guniganti, Brugumalla V Nitendra Saketh","doi":"10.4103/lungindia.lungindia_225_26","DOIUrl":"10.4103/lungindia.lungindia_225_26","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"480-481"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_816_25
R Saktheesh, Hariharan Iyer, Taruna Yadav, Vikrant Verma, Gopal Durgeshwar
{"title":"Echoes of a forgotten lesion: Bilateral lung masses and spontaneous pneumothorax: A clinicopathologic conference.","authors":"R Saktheesh, Hariharan Iyer, Taruna Yadav, Vikrant Verma, Gopal Durgeshwar","doi":"10.4103/lungindia.lungindia_816_25","DOIUrl":"10.4103/lungindia.lungindia_816_25","url":null,"abstract":"<p><strong>Abstract: </strong>A 23-year-old man presented with pleuritic chest pain, mild hemoptysis, and dyspnoea. Imaging revealed bilateral pleural-based masses with rupture, causing pneumothorax. This Clinicopathologic Conference highlights the differentials and there diagnostic reasoning, as well as the multidisciplinary discussions that led to the appropriate diagnosis of an uncommon lung mass.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"455-458"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_583_25
L B Pranav Varshan, Irfan Ismail Ayub, Sendilkumar Balasundaram
{"title":"MAD vs. AHI: Sleep patterns, oxygenation among polysomnography diagnosed by OSA patients.","authors":"L B Pranav Varshan, Irfan Ismail Ayub, Sendilkumar Balasundaram","doi":"10.4103/lungindia.lungindia_583_25","DOIUrl":"10.4103/lungindia.lungindia_583_25","url":null,"abstract":"<p><strong>Background and objective: </strong>Obstructive sleep apnea is a common sleep disorder characterized by repeated airway obstructive during sleep, leading to breating pauses, reduced sleep quality and decreased blood oxygen levels.</p><p><strong>Materials and methods: </strong>Polysomnographic data in Obstructive Sleep Apnea patients were analysed to explore correlations between Apnea Hypopnea Index, Mean Apnea hypopnea Duration, oxygen desaturation and sleep stages.</p><p><strong>Results: </strong>Among 136 Obstructive Sleep Apnea patients, Mean Apnea hypopnea duration showed a mild correlation with Apnea Hypopnea Index but no association with age, weight and height. Patients with longer Mean Apnea hypopnea duration had association ( P < 0.05) with poorer oxygenation, lower average saturation, loss of sleep, Mean oxygen desaturation, shorter sleep latency, less Non Rapid Eye Movement 3, more Non Rapid Eye Movement 1 and higher arousal/desaturation. After adjusting Apnea Hypopnea Index, Mean Apnea hypopnea duration remained significantly associated with Epworth Sleep Scale, sleep latency, Non Rapid Eye Movement 1/3, arousal index and all oxygen metrics. These associations were stronger in severe Obstructive Sleep Apnea ( n = 90), while in mild-moderate cases ( n = 46), only Non Rapid Eye Movement 3 duration correlated negatively with Mean Apnea hypopnea duration ( r = -0.14, P = 0.02).</p><p><strong>Conclusion: </strong>Mean apnea hypopnea duration emerged as an independent marker of oxygen desaturation and sleep disruption in OSA, beyond the Apnea Hypopnea Index. Its critical relevance was more pronounced in severe cases suggesting added value in assessing disease burden. Incorporating event duration into routine evaluation may refine patient stratification and guide targeted management strategies.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"418-422"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_75_25
V Shrinath, Ramakant Singh, Anoop Kumar Nair, R Ananthakrishnan
{"title":"Adenoviral pneumonia with organising features in an immunocompetent patient: When steroids make the difference.","authors":"V Shrinath, Ramakant Singh, Anoop Kumar Nair, R Ananthakrishnan","doi":"10.4103/lungindia.lungindia_75_25","DOIUrl":"10.4103/lungindia.lungindia_75_25","url":null,"abstract":"<p><strong>Abstract: </strong>Community-acquired pneumonia is a common lower respiratory tract infection (LRTI) causing significant mortality and morbidity. Though adenovirus is a common cause of LRTI in children, it rarely causes pneumonia in immunocompetent adults. Due to this, there is neither much medical literature nor standardised therapy for adenovirus pneumonia. We report a 35-year-old immunocompetent woman who developed adenovirus pneumonia with hypoxemic respiratory failure. She was managed with ribavirin and corticosteroids. Though cidofovir has demonstrated potential efficacy, its clinical use is limited by cost, availability and significant renal and haematologic toxicity. The documented potential therapeutic effects of ribavirin and steroids are restricted to a few case reports. The patient demonstrated an excellent response to corticosteroid therapy, making it a potential therapeutic tool to manage severe adenovirus pneumonia.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"438-441"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2026-07-01Epub Date: 2026-06-24DOI: 10.4103/lungindia.lungindia_805_25
Rajesh Venkitakrishnan, Gouri Menon, Melcy Cleetus, R Divya, Anand Vijay, Hasha Thankam Somson, Susan John
{"title":"Asthma remission with benralizumab therapy in severe eosinophilic Indian asthmatics.","authors":"Rajesh Venkitakrishnan, Gouri Menon, Melcy Cleetus, R Divya, Anand Vijay, Hasha Thankam Somson, Susan John","doi":"10.4103/lungindia.lungindia_805_25","DOIUrl":"10.4103/lungindia.lungindia_805_25","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"43 4","pages":"462-466"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}