Pakistan journal of medicine and dentistry最新文献_第3页

A Multilobulated Intramural Fibroid in Pregnancy: A Clinical Case Report 妊娠期多叶肌壁间子宫肌瘤：临床病例报告

Pakistan journal of medicine and dentistry Pub Date : 2024-01-20 DOI: 10.36283/pjmd13-1/020

引用次数: 0

Xantho-granulomatous Orchitis: A Rare Cause of Scrotal Swellings 黄疽性睾丸炎：阴囊肿胀的罕见病因

Pakistan journal of medicine and dentistry Pub Date : 2024-01-20 DOI: 10.36283/pjmd13-1/022

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Comparison of the Efficacy of Duloxetine Versus Pregabalin for Pain Relief of Neuropathy in Diabetics 度洛西汀与普瑞巴林在缓解糖尿病患者神经病变疼痛方面的疗效比较

Pakistan journal of medicine and dentistry Pub Date : 2024-01-20 DOI: 10.36283/pjmd13-1/003

{"title":"Comparison of the Efficacy of Duloxetine Versus Pregabalin for Pain Relief of Neuropathy in Diabetics","authors":"","doi":"10.36283/pjmd13-1/003","DOIUrl":"https://doi.org/10.36283/pjmd13-1/003","url":null,"abstract":"Background: Neuropathy is a common complication in diabetic patients with clinical manifestations of feet and hands paresthesia, pain in the lower legs, and a burning sensation in the soles. A wide variety of medications are used for diabetic neuropathy with varying degrees of pain relief reported. The study objective was to compare the efficacy of duloxetine versus pregabalin for pain relief of neuropathy in diabetics.\u0000\u0000Methods: The study was a six-week, single-blind, Randomized Controlled Trial conducted at HBS Medical and Dental College and Hospital in Islamabad. Patients were randomly designated to either of the groups (A or B) with 50 participants in each group. Group A received 150mg of pregabalin twice a day while group B received 60mg of duloxetine once a day. Pain relief was the primary outcome which was considered as a ≥ 50% decrease in pain score on the Visual Analog Scale at 6 weeks from baseline.\u0000\u0000Results: A total of 100 diabetic patients were registered in the study. The mean age in groups A&B was 48.36 and 50.56 (SD± 6.64) years respectively. The majority of the study population were males 39 (78%) and 42 (84%) in both groups. A total of 66% (n=33) in Group A and 74% (n=37) of the patients in Group B achieved pain relief. A comparison of the pain relief achieved between the two groups showed no statistical significance (p-value 0.383).\u0000\u0000Conclusion: The study revealed that duloxetine and pregabalin are both efficacious in terms of pain relief for diabetic neuropathy in our population.","PeriodicalId":471597,"journal":{"name":"Pakistan journal of medicine and dentistry","volume":"92 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dental Care Evaluation Among Children with Cerebral Palsy: A Special School Survey in Karachi 脑瘫儿童牙科护理评估：卡拉奇特殊学校调查

Pakistan journal of medicine and dentistry Pub Date : 2024-01-20 DOI: 10.36283/pjmd13-1/011

{"title":"Dental Care Evaluation Among Children with Cerebral Palsy: A Special School Survey in Karachi","authors":"","doi":"10.36283/pjmd13-1/011","DOIUrl":"https://doi.org/10.36283/pjmd13-1/011","url":null,"abstract":"Background: Children with Cerebral Palsy (CP) face malfunctioning in the motor system and go through difficulties in hearing, eating, sight, and musculoskeletal systems and are also mentally impaired. This may render them unable to maintain proper oral hygiene. The objective of this study was to evaluate oral hygiene in children with cerebral palsy in Karachi’s special schools.\u0000\u0000Methods: A cross-sectional study with a total of 80 CP children was conducted in special schools in Karachi using a purposive sampling technique. CP children aged 12-15, who consented via guardians/school and were able to comply with the procedure were included. CP children on medications or systemic diseases were excluded. Proforma containing demographic details, and dental history questions were asked. Oral examination was done using the Plaque index, Gingival index, and Oral hygiene index simplified was observed.\u0000\u0000Results: In this study, there were 48 (60%) males and 32 (40%) females. The mean ± SD of age was 14.4 ±1.4. Independent t-test showed that there was a significant association of gingival index means with the institutes selected (p=0.004). The other parameters PI and OHIS did not show any association. Mean PI (mean 1.99, SD 0.62) and GI (mean 1.9, SD 0.60) showed moderate plaque and gingival inflammation and poor oral hygiene index (mean 3.31, SD 1.3). ANOVA showed associations of PI, GI & and OHIS with dental habits.\u0000\u0000Conclusion: CP children have poor oral hygiene status and therefore need early diagnosis and prompt treatment to prevent complications.","PeriodicalId":471597,"journal":{"name":"Pakistan journal of medicine and dentistry","volume":"1 5-6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140502001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trend of Non-Alcoholic Fatty Liver Disease in Type II Diabetes Mellitus II 型糖尿病患者的非酒精性脂肪肝趋势

Pakistan journal of medicine and dentistry Pub Date : 2024-01-20 DOI: 10.36283/pjmd13-1/004

{"title":"Trend of Non-Alcoholic Fatty Liver Disease in Type II Diabetes Mellitus","authors":"","doi":"10.36283/pjmd13-1/004","DOIUrl":"https://doi.org/10.36283/pjmd13-1/004","url":null,"abstract":"Background: Non-alcoholic fatty liver disease (NAFLD) is becoming quite common in Type II Diabetes Mellitus (TIIDM) as obesity and insulin resistance are common within TIIDM and it is becoming a widespread liver condition globally. This study evaluated the prevalence of NAFLD patients who also had type II diabetes.\u0000\u0000Methods: The demographic data (name, age, body mass index (BMI), gender, occupation, duration of TIIDM, and treatment taking for TIIDM), as well as the results of the tests for these enzymes, were also recorded. Alanine transaminase (ALT) and Aspartate transaminase (AST) levels, as well as abdominal ultrasound findings of the liver, were recorded in a proforma after informed consent for a total of 200 Type II diabetic patients. Using SPSS, the data were analyzed, and stratified groups were subjected to the Chi-square tests.\u0000\u0000Results: There was a significant difference (p<0.05) observed in NAFLD patients of TIIDM concerning age, gender, BMI, treatment, occupation, and duration of diabetes. The sample size consisted of 200 patients of which 111 (55.5%) were men and 89 (44.5%) were women. Patients ranged in the age range of 40-70 years old, with a mean age of 55.08 ± 8.98 years and a mean BMI of 29.69±4.04, respectively. It was concluded that 64% of cases with diabetes mellitus had NAFLD.\u0000\u0000Conclusion: TIIDM is an independent risk factor for NAFLD so early screening, diagnosis, and appropriate treatment are mandatory to reduce the risk of NAFLD and its related complications.","PeriodicalId":471597,"journal":{"name":"Pakistan journal of medicine and dentistry","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From The Chief Editor’s Desk 总编辑的办公桌上

Pakistan journal of medicine and dentistry Pub Date : 2023-01-30 DOI: 10.36283//pjmd12-1/001

引用次数: 0