Indian Journal of Surgical Oncology最新文献

{"title":"Clinicopathological Correlation of BI-RADS FAC 4 Breast Lesions: A Retrospective Study from a Tertiary Cancer Centre in South India.","authors":"Paul Augustine, Dinesh Manchikanti, Rexeena V Bhargavan, Jagannath Krishna K M, Anitha Sen, Kurian Cherian","doi":"10.1007/s13193-025-02435-0","DOIUrl":"10.1007/s13193-025-02435-0","url":null,"abstract":"<p><p>Breast Imaging Reporting and Data System (BI-RADS) is commonly used to assess breast lesions, with category 4 suggesting a suspicious lesion with malignancy risk ranging from 2%-95%. This study aimed to evaluate the predictive accuracy of BI-RADS FAC (Final Assessment Criteria) 4 lesions and its subcategories. This is a retrospective analysis of 230 women with BI-RADS FAC 4 lesions detected on mammography and /or ultrasound at a South Indian tertiary centre over a 3-year period. Demographic, clinical, radiological features were correlated with histopathological data. Positive Predictive Value (PPV) of BI-RADS 4 lesions and its subcategories were calculated. Of 230 women, with BI-RADS-FAC 4 lesions in the study population, 26.9% were malignant. PPVs of BI-RADS FAC 4A lesions was 18.7%, 4B lesions was 27.6% and 4C lesions was 50.0%. Patients with a prior history of breast cancer had a malignancy rate of 34.9% for BI-RADS 4 lesions. In comparison, patients without a prior history of breast cancer had a malignancy rate of 21.5%. This difference was statistically significant (<i>p</i> = 0.001). BI-RADS FAC 4A PPV exceeded typical lexicon values of 2 to 10% risk of malignancy. There was no significant correlation between age, menopausal status, palpability and, BI-RADS FAC 4 sub-category. The risk of malignancy in BI-RADS FAC 4 lesions in our Indian population is high especially if there is a history of breast cancer. There should be a high index of suspicion for malignancy with appropriate surgical intervention in all patients with BI-RADS FAC 4 lesions.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1403-1408"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Contrast-Enhanced Mammography with MRI for Preoperative Assessment of Breast Cancer: A Pilot Study.","authors":"Ritu Thakur, S V S Deo, Ekta Dhamija, Ashutosh Mishra, Jyoti Sharma, Sandeep Mathur, Amitabha Mandal","doi":"10.1007/s13193-025-02417-2","DOIUrl":"10.1007/s13193-025-02417-2","url":null,"abstract":"<p><p>This study aimed at evaluating the role of contrast-enhanced mammography (CEM) for detection of multifocal/multicentric disease as compared to MRI in patients with breast carcinoma (BC). The study commenced after obtaining the institute's ethics approval. All included patients underwent CEM and MRI within an interval of 2 weeks. Images were interpreted as per the respective BIRADS lexicon. In addition to the baseline assessment of the index mass and its size, each modality was specifically evaluated for the presence of any additional findings like satellite lesions or non-mass enhancement, which were categorized as multifocal or multicentric disease depending on the location of additional lesions. Histopathology was considered the gold standard to ascertain the malignant nature of additional findings, wherever possible. Majority of the patients in our study had early T stage with clinical T2 (48.6%) followed by T1 stage (25.7%). Additional lesions could be identified in 34 (97.1%) patients on both CEM and MRI. Multifocality of the disease was seen in 23 patients (67.6%) with a median size of 1.2 cm and multicentricity in 11(32.3%) patients with a median size of 1.45 cm on CEM. Multifocality of the disease was seen in 21(61.7%) with a median size of 1.4 cm and multicentricity in 13 patients with a median size of 2 cm on MRI. CEM offers good correlation with MRI for determining the disease extent and multifocal/multicentric disease estimation. It is a new emerging modality and preliminary results showed comparable performance of CEM with MRI. Both the modalities have their inherent advantages and limitations; and longitudinal studies with large sample sizes are needed for further validation and clinical application.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1248-1256"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awake Nebulized Indocyanine Green (ICG) for Tracheobronchial Fluorescence: A Safety and Feasibility Study in Minimally Invasive Esophagectomy.","authors":"Shiv Rajan, Vijay Kumar, Mandeep Singh, Arun Chaturvedi, Sanjeev Misra","doi":"10.1007/s13193-025-02428-z","DOIUrl":"10.1007/s13193-025-02428-z","url":null,"abstract":"<p><p>Indocyanine green (ICG) imaging has shown potential in improving minimally invasive esophagectomy (MIE) safety in many ways. However, the risk of tracheobronchial tree injury remains a major concern. Real-time ICG-guided tracheobronchial fluorescence (TBF) is an innovative application of this technology for preventing such injuries. This study aimed to evaluate the feasibility and safety of nebulized ICG administered using an affordable nebulizer during the awake position to achieve TBF during the single-lung ventilation phase of MIE. An observational study was conducted on 30 consecutive patients undergoing McKeown's MIE. A compressor-type nebulizer was used to administer 5 ml (2.5 mg/ml) of aerosolized ICG before anesthesia induction. The real-time TBF was assessed with a near-infrared imaging system during the thoracic phase. All 30 patients had locally advanced squamous cell carcinoma and received neoadjuvant therapy. Of these, 21 (70%) had tumors in the middle third. Median time for nebulization was 9 min (8-11), and the time interval between this and the first TBF visualization was 90 min (80-150). TBF visualization was achieved in 30/30 (100%) and persisted throughout the thoracic phase in all (100%). No intraoperative tracheobronchial injury or ICG allergy was observed. Grade 3 or 4 pulmonary complications occurred in 13.3% of cases. Administering nebulized ICG while awake results in effective real-time TBF during MIE, improving surgical precision and safety. This simple, affordable, and reliable method shows promise for decreasing airway-related complications and improving outcomes in esophageal cancer surgery.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1272-1278"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Multiparametric MRI PIRADS Scoring with Histopathological Outcomes and Prognostic Significance in Prostate Cancer: A Tertiary Care Center Study.","authors":"Kudunthail Jeena R, Navriya Shiv Charan, Choudhary Gautam Ram, Singh Mahendra, Bhirud Deepak, Sandhu Arjun S, Yadav Taruna, Rao Meenakshi","doi":"10.1007/s13193-025-02420-7","DOIUrl":"10.1007/s13193-025-02420-7","url":null,"abstract":"<p><p>The objective of this study was to investigate the correlation between Prostate Imaging Reporting and Data System (PIRADS) scores obtained from multiparametric magnetic resonance imaging (mpMRI) and histopathological outcomes, including Gleason grades and adverse prognostic factors, in patients undergoing prostate biopsy for suspected prostate cancer. This retrospective study included 195 patients who underwent mpMRI and transrectal ultrasound-guided biopsy. PIRADS scores were assigned based on the PIRADS v2.1 guidelines, and biopsy specimens were evaluated for clinically significant prostate cancer (CSPCa), defined as Gleason score ≥ 7, as well as for adverse features such as Extracapsular Extension (ECE), Lymphovascular invasion (LVI), and Perineural invasion (PNI). Diagnostic accuracy of PIRADS scores was assessed using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Among 195 patients who underwent biopsy, PIRADS 3 lesions had a PPV of 20.00% for CSPCa, with 42.86% negative biopsy results. PIRADS 4 and 5 lesions showed higher PPVs for CSPCa at 71.43% and 86.00%, respectively. The majority of patients with PIRADS 3 lesions had Gleason 6 cancers, while PIRADS 4 and 5 lesions were significantly associated with higher Gleason scores (≥ 7). PIRADS 5 lesions had the highest rates of adverse features, including ECE (38%), LVI (14%), and PNI (24%), compared to PIRADS 4 and 3 lesions. Diagnostic accuracy was highest for PIRADS 4-5 lesions, with a sensitivity of 78%, specificity of 75%, and area under the curve (AUC) of 0.82, while PIRADS 3 lesions had a lower sensitivity (24%) and AUC (0.65). Higher PIRADS scores are significantly associated with an increased Likelihood of CSPCa, more aggressive Gleason grades, and adverse pathological features. PIRADS 4-5 lesions demonstrate high diagnostic accuracy for CSPCa, supporting their use in guiding biopsy decisions and treatment planning. PIRADS 3 lesions, though less predictive, still warrant individualized management, with some cases presenting aggressive disease. These findings reinforce the clinical utility of PIRADS scoring in prostate cancer risk stratification.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1217-1222"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large Sized Early Gastric Cancer Stomach Resected with Laparoscopic and Endoscopic Cooperative Surgery After Repeated Inconclusive Biopsy-A Diagnostic Application of LECS.","authors":"Syed Afroze Hussain, Aditya Kalyan, Suhaildeen Kajamohideen","doi":"10.1007/s13193-025-02415-4","DOIUrl":"10.1007/s13193-025-02415-4","url":null,"abstract":"","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1462-1463"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Clinical Characteristics, and Mortality of Stauffer Syndrome in Clear Cell Renal Carcinoma: Evidence From a Tertiary Care Hospital in South India.","authors":"Santhosh Srinivasan, Pankaj Bhirud, Poulose Chally, Abdul Azeez","doi":"10.1007/s13193-025-02421-6","DOIUrl":"10.1007/s13193-025-02421-6","url":null,"abstract":"<p><p>To estimate the prevalence of Stauffer syndrome in clear cell type renal cell carcinoma, describe the clinical characteristics and mortality of patients with Stauffer syndrome, and determine predictors of mortality in these patients. A retrospective cohort study was conducted at a tertiary care hospital in India, using data from January 2001 to March 2015 with 193 patients with clear cell variant of RCC. Data were collected from hospital records. Kaplan-Meier survival curves, and Cox proportional hazard models were used for analysis. Out of 193 patients with RCC, 32 (16.6%; 95% CI: 11.2 to 22.0%) were diagnosed with Stauffer syndrome. The mean age was 53.9 years (SD 11 years), with 83.9% (<i>n</i> = 162) being male. Haematuria (<i>n</i> = 11, 34.4%) and abdominal pain (<i>n</i> = 7, 21.9%) were the commonest symptoms. Among liver function tests, the most frequently elevated enzyme was alkaline phosphatase (<i>n</i> = 9, 28.1%), followed by total bilirubin (<i>n</i> = 7, 21.9%), SGPT (<i>n</i> = 6, 18.8%), and SGOT (<i>n</i> = 5, 15.6%). A higher proportion of this group (<i>n</i> = 20, 62.5%) presented with Fuhrman's grade 3 & 4 compared to patients without Stauffer syndrome (<i>n</i> = 64, 40%). The five-year survival rate for Stauffer syndrome patients was 89.3% (95% CI: 70 to 96.4%), a little higher than patients without Stauffer syndrome (80.1%; 95% CI: 71.5 to 86.3%), though statically not significant (hazard ratio: 0.47; 95% CI: 0.13 to 1.65, <i>p</i> = 0.24). Stauffer syndrome is a notable paraneoplastic condition in RCC, crucial for pre-operative diagnosis due to its prognostic implications. Further multi-centric studies are needed to improve the evidence quality.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1316-1322"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Surgical Fixation on Quality of Life in Patients with Metastatic Bone Disease: A Retrospective Analysis.","authors":"Vikas Maheshwari, Mohit Dhingra","doi":"10.1007/s13193-025-02436-z","DOIUrl":"10.1007/s13193-025-02436-z","url":null,"abstract":"<p><p>Bone is a common site for metastasis from various malignancies and is considered a poor prognostic indicator for both life expectancy and quality of life. Skeletal metastases lead to severe pain and pathological fractures, significantly impairing patients' daily functioning and well-being. Effective management of impending and pathological fractures is crucial in improving these patients' quality of life. To evaluate the quality of life in patients with metastatic bone disease who underwent surgical treatment for impending and pathological fractures of the lower limb at a tertiary care hospital. This retrospective observational study included patients who underwent surgical intervention for impending and pathological fractures of the lower limb due to metastatic bone disease. Functional outcomes were assessed using the Hindi-translated Indian version of the Toronto Extremity Salvage Score (TESS) for the lower limb. A total of 22 patients were included, with a mean age of 50 years (SD 17.9). The average TESS score for all patients was 48.8 (SD 20.02). The mean follow-up period was 15 months (range 3-56 months). A statistically significant difference in TESS scores was observed when age was considered as a variable (p < 0.05), indicating an age-related impact on functional outcomes. Prophylactic and therapeutic fixation of metastatic fractures significantly improves the quality of life in patients with metastatic bone disease. The use of the Indian version of the TESS questionnaire provided valuable insights into functional outcomes and quality of life in the Indian population.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1345-1349"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phosphaturic Mesenchymal Tumor Masquerading as Giant Cell Tumor in an Elderly Woman: A Diagnostic Challenge.","authors":"Sunayana Misra, Sonia Badwal, Deepika Gupta, Ritu Verma","doi":"10.1007/s13193-025-02410-9","DOIUrl":"10.1007/s13193-025-02410-9","url":null,"abstract":"","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1458-1461"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ABSI 2025 Consensus Guidelines on the Management of Breast Cancer in Low- and Middle-Income Countries.","authors":"S P Somashekhar, Pankaj Kumar Garg, S V S Deo, Vijay Devanhalli, Navneet Kaur, Sanjit Kumar Agrawal, Nita Sukumar Nair, Ashutosh Mishra, Manish Kumar Gaur, Rohit Kumar, Diptendra K Sarkar, Raghu Ram Pillarisetti","doi":"10.1007/s13193-025-02429-y","DOIUrl":"10.1007/s13193-025-02429-y","url":null,"abstract":"<p><strong>Background: </strong>The Association of Breast Surgeons of India (ABSI) periodically publishes national consensus statements to adapt evidence-based breast cancer management to Indian realities. This 2025 update aimed to develop pragmatic, scenario-based guidance and assess concordance between expert recommendations and current clinical practice.</p><p><strong>Methods: </strong>An expert panel formulated 40 single-best-answer questions spanning screening, diagnosis, surgery, axillary management, reconstruction, systemic therapy, radiotherapy, genetics, survivorship, and delivery of care. Responses were collected from panel experts (<i>n</i> = 24) and delegates (<i>n</i> = 159) at the ABSI Annual Meeting 2025 (Kolkata) using identical Google Forms. Concordance was defined a priori: almost 100% (same top choice, ≥ 90% in both groups), small discordance (same top, ≤ 10% difference), medium discordance (same top, 10-30% difference), significant discordance (> 30% difference or different top choice). Option distributions were compared using chi-square tests.</p><p><strong>Results: </strong>Of 40 questions, 10 showed almost complete concordance, 12 small discordance, 17 medium discordance, and 1 significant discordance. Highest agreement included the following: empowering community health officers for early detection, preference for breast-conserving surgery when feasible, SLNB for node-negative early breast cancer, and mandatory fertility/psycho-sexual counselling for young patients. Divergences were noted in HER2 therapy duration in low-risk disease, radiotherapy in DCIS, reconstruction choices, and axillary management in Z0011-eligible macro-metastasis.</p><p><strong>Conclusion: </strong>Indian experts and practising surgeons show strong alignment on core surgical principles and supportive care priorities. Targeted guidance is needed for areas of practice variation to ensure uniform, evidence-informed care delivery in India.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1279-1290"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic Versus Open Radical Nephrectomy for Renal Cell Carcinoma: A Retrospective Study.","authors":"Amr Abouzid, Mosab Shetiwy, Mohamed Hamdy, Khalid Atallah, Mohamed Ezzat, Mohamed Abd Elghaffar","doi":"10.1007/s13193-025-02409-2","DOIUrl":"10.1007/s13193-025-02409-2","url":null,"abstract":"<p><p>Laparoscopic radical nephrectomy (LRN) became a popular and standard treatment for renal cancers in comparison with open radical nephrectomy (ORN). Between 5 May 2008 and 10 October 2023, we retrospectively reviewed 74 patients with renal cell carcinoma at the Oncology Center, Mansoura University, who were treated with either laparoscopic or open radical nephrectomy with the assessment of the surgical and postoperative outcomes and the impact of both approaches on the patient's prognosis. The operative time in the LRN group was 166.76 ± 55.69 min and was comparable with that in the ORN group at 164.5 ± 51.68 min (<i>p</i> = 0.86). The intraoperative blood loss significantly differed between both groups with 101.47 ± 49.79 ml in the LRN group and 270.63 ± 123.22 ml in the ORN group (<i>p</i> < 0.001). The surgical outcomes such as ambulation, starting oral intake, and in-hospital stay were statistically significant between both groups (<i>p</i> < 0.001). We followed up with the patients within 40.74 months (range 2-279 months), and the tumor recurred in the LRN and ORN groups in 3 and 4 cases, respectively. Laparoscopic radical nephrectomy in comparison to open radical nephrectomy for renal cell carcinoma has better surgical and postoperative outcomes in experienced hands and in small-sized tumors.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"17 6","pages":"1362-1368"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13315018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148362901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}