Indian Journal of Surgical Oncology最新文献

{"title":"Feasibility of Doing a Safe Robotic Thyroidectomy in a Developing Country and Comparison of 2 Different Techniques.","authors":"Mudit Agarwal, Abhishek Singh, Shreya Rai, Ronak Bharadwaj, Gitanjali Deshpande","doi":"10.1007/s13193-024-02154-y","DOIUrl":"10.1007/s13193-024-02154-y","url":null,"abstract":"<p><p>This study aims to present our experience with robotic thyroidectomy approaches for differentiated thyroid carcinoma (DTC) vis a vis Modified BABA (Bilateral Axillo Breast Approach) and Retroauricular approach. Retrospective observational single institution-based study comprising 19 patients who underwent robotic thyroid surgery for DTC between October 2018 and January 2022. All patients underwent robotic thyroidectomy using the da Vinci Xi Robotic surgical system. Nineteen patients underwent robotic thyroidectomy with none needing conversion to open surgery. The Modified BABA approach was used for 9 patients (47%), whereas the Retroauricular approach (RA) was used for 10 patients (53%). In the RA group, 6 patients (60%) underwent total thyroidectomy and 4 patients (40%) underwent hemithyroidectomy. The Modified BABA approach was used for total thyroidectomy in 8 (89%) patients whereas 1 patient (11%) underwent hemithyroidectomy utilizing this approach. In 10 patients, central compartment clearance was done (5 through Modified BABA and 5 through RA). Lateral neck nodes were addressed in 4 patients (1 through Modified BABA and 3via RA). The median hospital stay was 4 days (range: 2-6 days). None of the 19 patients had post-operative complications like RLN palsy or any scar-related complaints /hypertrophic scars. The average PTH value post-op was 32.1 pg/ml (range: 3.8-70.4 pg/ml). Based on the current evidence from the literature, robotic thyroidectomy for thyroid carcinoma stands out from conventional surgery by resulting in sound oncological clearance with a superior cosmetic result by avoiding a scar in the anterior neck.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"837-847"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI Chatbots in Oncology: A Comparative Study of Sider Fusion AI and Perplexity AI for Gastric Cancer Patients.","authors":"Amirhosein Naseri, Mohammad Hossein Antikchi, Maedeh Barahman, Ahmad Shirinzadeh-Dastgiri, Seyed Masoud HaghighiKian, Mohammad Vakili-Ojarood, Amirhossein Rahmani, Amirhossein Shahbazi, Amirmasoud Shiri, Ali Masoudi, Maryam Aghasipour, Kazem Aghili, Hossein Neamatzadeh","doi":"10.1007/s13193-024-02145-z","DOIUrl":"10.1007/s13193-024-02145-z","url":null,"abstract":"<p><p>The integration of AI chatbots in healthcare, particularly for young adults diagnosed with gastric cancer, offers a novel approach to enhancing patient support and information access. This evaluation examines the effectiveness of two AI chatbots, Sider Fusion AI Bot, and Perplexity AI, in improving patient outcomes, alleviating anxiety, and promoting informed decision-making. A comparative study design was employed, utilizing a structured rubric guided by experienced gastroenterologists to assess the performance of both chatbots. Evaluation criteria included competency, accuracy, relevance, informativeness, and support capabilities. The study focused on a case involving a 21-year-old male with advanced gastric adenocarcinoma. Both chatbots demonstrated high competency and relevance scores, achieving perfect scores of 5. However, they received low accuracy scores of 1, indicating a need for scrutiny in specific details. Sider Fusion AI Bot excelled in informativeness (score of 5) and support capabilities (rated \"high\"), while Perplexity AI scored 4 in informativeness and was rated \"moderate\" for support. Both systems provided essential recommendations for alleviating anxiety and emphasized informed decision-making, but Sider Fusion AI Bot offered a more comprehensive discharge plan. The study highlights the strengths and weaknesses of AI chatbots in oncology, emphasizing the importance of tailored communication styles to enhance patient engagement and outcomes. Sider Fusion AI Bot's superior capacity for detailed explanations and user engagement positions it as a potentially more valuable tool in clinical decision-making. Ongoing research is necessary to address limitations and optimize the integration of AI chatbots in healthcare settings, ensuring they effectively complement human interactions.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"827-836"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synovial Sarcoma of Testis: a Rare Tumour at an Uncommon Site-A Case Report.","authors":"Nikhil Saurabh, Debanga Sarma, Sasanka Kumar Barua, T P Rajeev, Puskal Kumar Bagchi, T Manjunath, Mandeep Phukan","doi":"10.1007/s13193-024-02147-x","DOIUrl":"10.1007/s13193-024-02147-x","url":null,"abstract":"<p><p>Neoplasms of testis are relatively rare with an incidence of approximately 1% of cancers in men diagnosed worldwide. Germ cell tumours form around more than 95% of testicular neoplasm. Primary synovial sarcoma of testis is exceedingly rare and soft tissue sarcoma forms around 1% of all adult malignancies. Among sarcomas, synovial sarcoma is about 5 to 10%. It is a mesenchymal tumour which affects children and young adults and mostly involves extremities. This is the second case being reported in the literature. We report the case of a 35-year-old man who presented with a left testicular mass and underwent radical high inguinal orchiectomy. Lost to follow-up, he returned with a recurrent mass in the left inguinoscrotal region. He underwent wide local excision with systemic chemotherapy (a combination of ifosfamide and doxorubicin)and radiotherapy postoperatively. He succumbed to the disease in a year. The prognosis is guarded as the optimal therapy is unknown.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"848-852"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Surgical Apgar Score in Predicting Post-operative Complications After Whipple Procedure in Pancreatic Cancer Patients.","authors":"Nilanjana Howbora, Raghu S Thota, Sagar Pargunde, Vijaya Patil, Vandana Agarwal, Manish Bhandare, Shailesh V Shrikhande","doi":"10.1007/s13193-024-02151-1","DOIUrl":"10.1007/s13193-024-02151-1","url":null,"abstract":"<p><p>An intraoperative 10-point Surgical Apgar Score, based on estimated blood loss, lowest mean arterial pressure, and lowest heart rate, was developed and validated for predicting postoperative complications in patients undergoing vascular and general surgeries. We sought to estimate the ability of this metric to predict major postoperative complications in patients with pancreatic cancer undergoing the Whipple procedure. This is a prospective, observational, single-centre study involving adult patients undergoing the Whipple procedure, at a major tertiary cancer centre. All eligible patients undergoing Whipple surgery in our institute between March 2018 and October 2021 were included in the study. Demographic data, clinicopathological characteristics, comorbidities, intraoperative variables, and postoperative complications were analyzed. The surgical score was calculated from intraoperative blood loss, lowest heart rate, and lowest mean arterial pressure. All the patients were followed up till 30 days postoperatively. Descriptive statistics and univariate and multivariate analyses were used as appropriate. The occurrence of major postoperative complications represented the primary outcome. A total of 253 patients were analyzed. The mean duration of surgery was 436 min. On statistical analyses, the occurrence of major postoperative complications was significantly associated with SAS ≤ 4 (OR = 8.00, 95% CI = 3.78-16.93, <i>p</i> = 0.000), use of intraoperative vasopressor (OR = 2.247, 95% CI = 1.312-3.846, <i>p</i> = 0.003), and body mass index (BMI) (OR = 1.074, 95% CI = 1.010-1.142, <i>p</i> = 0.022). However, we did not find any significant association between other demographic variables like age, comorbidities, duration of surgery, and preoperative s. albumin with the occurrence of postoperative complications. Lower SAS (≤ 4) is the most powerful predictor of postoperative complications in pancreatic cancer patients undergoing Whipple surgery. The score provides a simple and immediate means of measuring and communicating patient outcomes, using data routinely available in any setting.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"819-826"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of the Clinical and Radiological Features in the Management of Bethesda 3 and 4 Thyroid Nodules.","authors":"Shivakumar Thiagarajan, Swapnil Rane, Khusbhu Chandak, B Gurukeerthi, Teja Kantamani, Vidisha Tuljapurkar, Suman Kumar, Gouri Pantvaidya","doi":"10.1007/s13193-024-02167-7","DOIUrl":"10.1007/s13193-024-02167-7","url":null,"abstract":"<p><p>Deciding the right treatment strategy for patients with Bethesda 3 and 4 fine needle aspiration cytology (FNAC) reports may be challenging. The reported risk of malignancy (ROM) and those from high-volume institutes may not be identical. The cost of molecular testing and its unavailability for routine use limits its utility in decision-making. In this study, we included all patients diagnosed at our institute with Bethesda 3 and 4 thyroid nodules on FNAC between January 2012 and December 2021. We identified the risk of malignancy for these patients along with other factors that could help identify the possibility of malignancy in these thyroid nodules. We utilised the clinical (C), ultrasound features (U), and the Bethesda category (T) to derive the CUT score and derive a cut-off value beyond which malignancy could be predicted. A total of 359 patients were included in the study. The ROM for the Bethesda 3 thyroid nodule was 77.7% (167/215), and that for the Bethesda 4 thyroid nodule was 76.4% (110/144). On multivariate analysis, nodules taller than wider [0.006, 7.662 (1.806-32.5)], male gender [0.024, 2.359 (1.119-4.976)], and the presence of microcalcification [0.004, 2.328 (1.319-4.109)] were found to be significant for the presence of malignancy in the final histopathology. The CUT score > 8.875 was associated with malignancy in the final histopathology. Various clinical and radiological factors may be useful to identify the nodules harbouring malignancy and facilitate appropriate management. The rate of malignancy in Bethesda 3 and 4 nodules among those who underwent surgery in our cohort was higher.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s13193-024-02167-7.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"882-889"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Pattern of Recurrence after Curative Resection of Gastric Cancer in a Tertiary Cancer Center in North India.","authors":"Amitabha Mandal, Ritu Thakur, Chandan Kumar, Naveen Kumar, Sandeep Bhoriwal, Jyoti Sharma, S V S Deo, Atul Sharma, Sushmita Pathy, Vinod Kumar, Sunil Kumar","doi":"10.1007/s13193-024-02153-z","DOIUrl":"10.1007/s13193-024-02153-z","url":null,"abstract":"<p><p>To study the recurrence pattern according to the location of the tumor, predictors, and survival as per the type of recurrence in gastric cancer. Retrospective analysis of gastric cancer patients who underwent curative resection was done on a prospectively maintained computerized database from 2000 to 2021 in Dr. BRAIRCH, AIIMS, New Delhi. After a median follow-up of 50 months, 101 recurrences (50.75%) were detected among 199 curative resections. Recurrences were categorized into nonperitoneal distant (40.6%), peritoneal (28.7%), locoregional (22.8%), and mixed type (7.9%). For all the subsites most common type of recurrence was distant recurrence (Distal stomach- 38%, proximal stomach-55%, and body-41%). Most common site of recurrence was liver (32.7%), followed by peritoneum (28.7%), locoregional node (15.8%), mixed type (7.9%), anastomotic site (6.9%), lung (5.9%), and bone (2.0%). No statistically significant difference was noted among different subsites (<i>p</i> = 0.566), and specific site (<i>p</i> = 0.649). Weight loss, lymphovascular invasion, pathological stage, and pathological T stage, and node ratio are significant predictors of recurrence. Median disease-free survival was 29 months (95% CI-24.455-33.545). Median overall survival for peritoneal recurrence was 34 months (95%CI-31.48-36.52), distant site 38 months (95%CI-26.789-49.211), locoregional 51 months (95%CI-41.609-60.319), and mixed type 56 months (95%CI-47.684-64.316). Despite the improvement of multimodal management, recurrence is the main hindrance to survival. Distant and peritoneal recurrence are the major concern after curative resection of gastric cancer, with a less survival time compared to the locoregional and mixed type of recurrence.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"895-901"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Submandibular Gland Preservation in Oral Cavity Cancer is Oncologically Safe! Time to Think About Improving Quality of Life.","authors":"Mrudul Patel, Harshit Shah, Vishal Choksi","doi":"10.1007/s13193-024-02166-8","DOIUrl":"10.1007/s13193-024-02166-8","url":null,"abstract":"<p><p>Oral cavity squamous cell carcinoma (OCSCC) is the most common cancer among men and second most common cancer among women in India. Literature says that the submandibular salivary gland (SMG) can be involved by direct extension from the primary tumour (< 5%) or through metastatic node in level Ib (0.5-1.5%). Retrospective studies have shown that the SMG can be preserved in OCSCC except in those where the primary tumour or level 1b nodes are in close vicinity to the gland. The goal of our prospective observational study was to evaluate the involvement of SMG in OCSCC. We had enrolled a total of 142 patients from July 2018 to May 2020 fulfilling the selection criteria and planned for appropriate surgery with removal of the SMG. The postoperative histopathology report was then assessed to look for the involvement of SMG. We observed majority patients in their 4th-5th decade with mean age of 49 years. Majority of the primary tumor were staged as pT2-T3. Out of 142 patients, 76 (53.52%) were node-negative (pN0) and 66 (46.48%) were node-positive (pN +). Level Ib lymph node involvement was seen in 65.15% of the pN + cases. We did not find SMG involvement in any of the cases either from direct extension of primary tumor or from level Ib lymph node extranodal spread. We conclude that SMG involvement is extremely rare in OCSCC. It is better to preserve the gland for which a prospective study is warranted to assess the functional benefits of preserving the gland.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"890-894"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Retrospective Analysis of Ovarian Cancer Treatment Outcomes: Neoadjuvant Therapy with and without Surgical Intervention.","authors":"Ravi Iyengar, Gopireddy Murali Mohan Reddy, Parthiban Kumaresan","doi":"10.1007/s13193-024-02144-0","DOIUrl":"10.1007/s13193-024-02144-0","url":null,"abstract":"<p><p>Ovarian cancer, a leading cause of cancer-related mortality among Indian women, is predominantly diagnosed at advanced stages. The efficacy of neoadjuvant chemotherapy (NACT) versus traditional treatment approaches, including surgery, remains a critical area of investigation to improve patient outcomes. This retrospective observational study analyzed 84 patients with advanced ovarian carcinoma (stage IIIC or IV) treated at tertiary care center, Tamil Nadu. It compared survival outcomes between patients receiving NACT alone and those undergoing NACT followed by surgical intervention. Data on demographic characteristics, tumor size, ECOG performance status, menopausal status, ascites fluid cytology, and comorbidities were collected. Kaplan-Meier survival analysis and Cox regression were used for statistical assessment. The study found significant associations between treatment modality and survival outcomes. Tumor size, particularly T3, positive ascitic fluid cytology, and neoadjuvant chemotherapy significantly influenced recurrence risk. The overall survival time had a median of 9 years, and time to recurrence had a median of 8 years. Neoadjuvant chemotherapy, when combined with surgical intervention, demonstrated a potential improvement in survival outcomes. The integration of neoadjuvant chemotherapy with surgical intervention may offer beneficial outcomes for patients with advanced ovarian cancer. This study underscores the importance of tailored treatment approaches, emphasizing the role of NACT in the therapeutic landscape of ovarian cancer.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"876-881"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tiny Fighter, Fierce Disease: Coexistence of Anaplastic Large Cell Lymphoma with Situs Inversus Totalis.","authors":"Md Ali Osama, Pratima Kukreja, Pratiksha Sharma, Priti Singh, Deeksha Singh, Praveen Kumar","doi":"10.1007/s13193-024-02152-0","DOIUrl":"10.1007/s13193-024-02152-0","url":null,"abstract":"","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"853-857"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisit the Benefit of Transanal Local Excision for Two Cases of Large Prolapsing Malignant Rectal Polyps.","authors":"Jih Huei Tan, Mohamed Rezal Abdul Aziz, April Camilla Roslani","doi":"10.1007/s13193-024-02165-9","DOIUrl":"10.1007/s13193-024-02165-9","url":null,"abstract":"<p><p>Transanal local excision was traditionally practiced to remove rectal polyps or early rectal tumor. Since 1980, Buess et al. have recommended the use of endoscopy technology for transanal endoscopic microsurgery (TEM). This technique was not popular due to technical issues of difficult positioning, tricky technique especially when it was introduced in the pre-laparoscopy era. With the inception of flexible endoscopy technology, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) came in as alternative options for colorectal polyps. However, both these flexible endoscopy techniques have their disadvantages. The earlier had the issues of fragmented specimens, the latter is technically more challenging with higher risk of perforation/bleeding. Therefore, the traditional transanal excision surgery remained popular and a cost-effective option. Here, we reported 2 cases of large malignant rectal polyps with broad-based pedicle. Both the patients' polyps are prolapsing and can be everted out from the anal canal. With this specific anatomical criterion, we observed that the surgical treatment can be simplified with conventional transanal local excision with minimal blood loss and quicker and good complete resection rate. Adding that, it abates the cost from the aforementioned newer endoscopic technique.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 4","pages":"902-904"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}