Indian Journal of Surgical Oncology最新文献

{"title":"Internal Jugular Vein Reconstruction with Cephalic Vein Interposition Graft: A Case Report and Review of Literature.","authors":"Purushottam Chavan, Guru Keerthi B, Greeshma Upadhya, Jaykumar V Patel, Gaurang Singhal, Roopa Malali","doi":"10.1007/s13193-024-02063-0","DOIUrl":"10.1007/s13193-024-02063-0","url":null,"abstract":"<p><p>At times, radical neck dissection may necessitate the sacrifice of bilateral internal jugular veins due to extensive nodal disease. This can lead to serious consequences such as the risk of blindness, potentially catastrophic laryngeal edema, stroke, and even death if the internal jugular vein (IJV) is absent or occluded. The reconstruction of the IJV presents an opportunity to mitigate these risks and their subsequent effects, whether performed during or after the neck dissection. The external jugular vein is commonly utilized for anastomosis when reconstructing the IJV, but its availability may be limited at times, prompting the consideration of alternative options. We present the case of a 50-year-old male patient with supraglottic malignancy (cT2N1M0), who had previously undergone chemo-radiotherapy. After a disease-free interval of 9 months, the patient experienced a nodal recurrence at bilateral level III. Subsequently, he underwent bilateral lateral neck dissection, involving the sacrifice of bilateral internal jugular veins due to extensive extranodal spread. The left-sided internal jugular vein was re-anastomosed using a right cephalic vein interposition graft. During the last follow-up, the disease was locoregionally controlled, with no observed neck lymphedema, and the patient maintained a functional larynx with good speech and swallow. Internal jugular vein re-anastomosis with a cephalic vein interposition graft proves to be a viable alternative in cases involving bilateral IJV ligation.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"198-202"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastasis to Thyroid from Recurrent Head and Neck Squamous Cell Carcinoma: A Case Series and Review of Literature.","authors":"Avneet Kaur, Rohit Nayyar, Harit Kumar Chaturvedi, Akshat Malik","doi":"10.1007/s13193-024-02054-1","DOIUrl":"10.1007/s13193-024-02054-1","url":null,"abstract":"<p><p>Metastasis to the thyroid gland from a squamous head and neck primary is extremely rare. We present three cases of recurrent head and neck squamous cell carcinoma with squamous metastasis to the thyroid gland. The surgery was done in two cases where the disease was resectable and limited, whereas due to extensive disease, the third case was managed with palliative chemotherapy. There was an early disease progression in all patients, including those treated surgically. Due to the limited number of reported cases of head and neck squamous cell cancers metastasizing to the thyroid gland, data regarding their prognosis and management is insufficient. We still need further data to identify patients who can benefit from surgical resection in such scenarios.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"122-126"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional Anesthesia Techniques for Breast Cancer Surgeries-A Narrative Review.","authors":"Raghuraman M Sethuraman","doi":"10.1007/s13193-024-02043-4","DOIUrl":"10.1007/s13193-024-02043-4","url":null,"abstract":"<p><p>Postoperative pain of breast cancer procedures can be debilitating and if not treated properly can lead to acute and chronic complications. Regional anesthesia techniques are very useful in providing adequate pain relief and can be applied either as a supplement to general anesthesia or surgical anesthesia in these surgeries. The application of ultrasound has revolutionized the field of regional anesthesia for breast cancer procedures, especially in the last decade. A thorough understanding of the application of each technique with precise knowledge of the sensory supply of the breast and axilla and the types of breast cancer surgeries can help us to choose the proper technique(s). In this article, the commonly used regional anesthesia techniques for breast cancer surgeries are discussed.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"127-133"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel Lymph Node Biopsy Evaluation in Early Stage T1, T2, N0, Squamous Cell Carcinoma of the Oral Cavity with Methylene Blue Dye.","authors":"Amit Kumar, Mahendra Singh Hada, Anjali Gupta, Sunil Samdhani","doi":"10.1007/s13193-024-02078-7","DOIUrl":"10.1007/s13193-024-02078-7","url":null,"abstract":"<p><p>This study aims to evaluate the expediency of the sentinel lymph node biopsy (SLNB) for the presence of occult node metastasis in patients with squamous cell carcinoma (SCC) of the oral cavity presenting with early-stage node-negative disease. A hospital-based descriptive type of cross-sectional study was conducted over a period of 1 year at a tertiary care hospital and referral center after approval by the institute ethical committee. Forty patients underwent SLNB using a peri-tumoral methylene blue dye injection. A total of 59 blue-dyed nodes were dissected in 34 cases and sent for frozen section analyses and histopathological examination (HPE). Elective neck dissection (END) was done in all 40 patients. The SLNB results were correlated with subsequent histopathological grading. Level IIA had the highest proportion of blue-stained sentinel nodes in 15 (37.5%) cases. The frozen section analysis has 75% sensitivity, 100% specificity, 100% positive predictive value (PPV), and 92.86% negative predictive value (NPV). The frozen section analysis of blue-stained sentinel nodes detected occult metastasis in 17.6% of cases (6 out of 34 patients), while subsequent HPE of the dye-stained sentinel nodes revealed positive occult metastasis in 23.5% of cases (8 out of 34 patients). Once SLN is detected on methylene blue, a higher detection rate of occult metastasis is present in comparison to dye-negative nodes. The use of sentinel lymph node biopsy can be a valuable diagnostic technique, especially in regions with limited resources, such as many parts of the developing world.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"245-250"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Institutional Insights into the Management and Surgical Resection of Tracheobronchial Lesions: Experience with 11 Patients.","authors":"Naveen Kumar Kushwaha, Pradeep Jaiswal, Vijay Pratap Singh, S Harish, Prashant Gupta","doi":"10.1007/s13193-024-02101-x","DOIUrl":"10.1007/s13193-024-02101-x","url":null,"abstract":"<p><p>Pathologic conditions affecting the central airways encompass a wide array of focal alterations. The diagnosis of central airway lesions poses considerable challenges due to their varied presentations, resulting in delayed recognition and management. However, advances in bronchoscopy and multidetector computed tomography (MDCT) aid in early detection. Management depends both on the pathology and the obstructive potential of the process. We present our experience with the comprehensive evaluation and management of 11 cases of focal tracheobronchial lesions surgically treated at our institution, with an emphasis on lung parenchyma preservation. This is a retrospective analysis of prospectively maintained data of 11 patients who were surgically treated for focal tracheobronchial lesions between January 2021 and December 2023 at a tertiary care hospital in India. Their demographic data, clinical presentation, and perioperative details were recorded. All patients underwent MDCT chest, bronchoscopy, and pulmonary function tests as part of the workup for diagnosis and assessment. The study included nine male and two female patients with a mean age of 36.4 years (range 9-64 years). Surgical procedures included main bronchus sleeve resection (3 patients), sleeve lobectomies (3 patients), sleeve bi-lobectomy (1 patient), and tracheal resection with end-to-end anastomosis (4 patients). Postoperatively, one patient died due to acute respiratory distress syndrome (ARDS). Pathological evaluation revealed malignant causes in 9 patients and non-neoplastic causes in 2 patients. The mean hospital stay was 6.5 days, with chest tube removal at 5.6 days. The average follow-up period was 8.2 months, ranging from 6 to 15 months. Based on our series, we ascertain that a complete resection, whenever feasible, offers optimal potential benefits and symptom alleviation for individuals with focal tracheobronchial lesions. Enhanced recognition of these lesions, coupled with a heightened level of suspicion and prompt diagnosis, stands pivotal in ensuring the safe and efficacious management of such cases.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"364-375"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early vs. Late Stoma Reversal After Open Low Anterior Resection Post-Neoadjuvant Chemoradiotherapy.","authors":"Fahad Bin Abdul Majeed, Madhu Muralee, Chandramohan","doi":"10.1007/s13193-024-02036-3","DOIUrl":"10.1007/s13193-024-02036-3","url":null,"abstract":"<p><p>Diversion stomas are done to protect the patients from anastomosis-related complications after low anterior resection, particularly after neoadjuvant chemoradiotherapy. Problems with these temporary stomas are the significant deterioration in quality of life along with medical and surgical complications. Diversion ileostomy is the most commonly performed diversion procedure. Reversal of stoma is usually done after completion of adjuvant chemotherapy. Studies looking into the safety of early stoma reversal have shown conflicting results. The objective of this work is to study the advantages, disadvantages, and complications associated with early ileostomy reversal when compared to late ileostomy reversal in patients undergoing stoma reversal that was done as part of open low anterior resection for rectal cancer. Total of 92 patients were recruited for the study during the time period March, 2018, to June, 2019; 12 patients did not fulfill the inclusion criteria. A total of 80 patients were analyzed, 39 of whom underwent early reversal and 41 underwent late reversal. All of whom were prospectively followed up to assess the quality of life and complications associated with early and late stoma reversals. Both groups of patients were similar in the baseline characteristics. Perioperative complications were found to be significantly increased in the late reversal group when compared to early reversal group (7 vs. 0 with <i>P</i> 0.043). Quality-of-life assessment showed significant improvement in patients who underwent early stoma reversal with significant improvement in raw score, functional score, and symptoms score (<i>P</i> < 0.001). Adjuvant chemotherapy was also not significantly delayed in the early reversal group. Early stoma reversal should be offered to patients after open low anterior resection post-NACTRT, as it is safer and associated with improvement in quality of life.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"16 1","pages":"94-99"},"PeriodicalIF":0.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Short Course of Preoperative Denosumab Injection Followed by Surgery in High-Risk Giant Cell Tumors of the Extremities: A Retrospective Study.","authors":"Sujit Kumar Tripathy, Saroj Das Majumdar, Siddharth Satyakam Pradhan, Paulson Varghese, Hrudeswar Behera, Anand Srinivasan","doi":"10.1007/s13193-024-01990-2","DOIUrl":"10.1007/s13193-024-01990-2","url":null,"abstract":"<p><p>Despite early promising results with denosumab treatment in giant cell tumor of bone (GCTB), recent studies have raised concerns about a high local recurrence rate following preoperative denosumab administration and joint preservation surgery. This retrospective study evaluated data from 25 high-risk GCT patients (Campanacci grade II or III with features like soft tissue extension, pathological fracture, minimal periarticular or subarticular bone) treated with five doses of neoadjuvant denosumab injection followed by either curettage and cementing (<i>n</i> = 13) or joint reconstruction with fibular graft/endoprosthesis (<i>n</i> = 12) between 2014 and 2019. With an average follow-up of 40 months, the study found only one patient of local recurrence. All patients were independently ambulant, with a mean MSTS score of 26.32. Subgroup analysis revealed an MSTS score of 27.76 in the joint preservation group, and 24.75 in the excision with reconstruction/prosthetic replacement group (unpaired <i>t</i>-test, <i>p</i>-value < 0.001). Five patients experienced postoperative complications, including two infections, one recurrence, one mediolateral instability in the prosthetic component, and one restriction of wrist movement. A short course of neoadjuvant denosumab, followed by curettage and cementing or wide excision with joint reconstruction/prosthetic replacement, appears to be an effective strategy for high-risk GCTB patients. This approach not only minimizes surgical morbidity but also does not increase the local recurrence rate. The short course regimen may present a cost-effective and practical option in clinical practice.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"15 4","pages":"825-836"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing Androgen Receptor Expression in Breast Cancer: Insights into Histopathological Parameters and Hormone Receptor Status Among Indian Women.","authors":"Nidhiben Harshadkumar Thakkar, Md Ali Osama, Shashi Dhawan","doi":"10.1007/s13193-024-01997-9","DOIUrl":"10.1007/s13193-024-01997-9","url":null,"abstract":"<p><p>Breast cancer, an exceptionally hormone-dependent tumor, exhibits a diverse clinical profile. Its therapeutic categorization relies on the expression of key receptors, namely, estrogen receptor (ER), progesterone receptor (PR), and Her2neu. The androgen receptor (AR), a member of the nuclear receptor superfamily, is a biomarker gaining attention in breast cancer research, particularly for triple-negative breast cancers. We conducted an analysis of AR expression in 113 primary breast cancer cases, using a cutoff criterion of ≥ 10% tumor cell positivity. ER, PR, and Her2neu statuses were determined based on the 2023 ASCO-CAP criteria. AR expression was then correlated with various clinicopathological factors, including age, menopausal status, centricity, histological type, grade, tumor size, nodal status, lymphovascular and perineural invasion, and ER, PR, and HER2neu statuses. Among the 113 cases, 57 (50.4%) showed positive AR expression. No statistically significant associations were found between AR expression and age, menopausal status, histological type, histological grade, nodal status, or ER and PR expression. Notably, all multicentric tumors (<i>n</i> = 7, 100%) were AR negative. AR expression was linked to smaller tumor sizes. Positive AR cases exhibited an association with Her2neu overexpression, particularly in ER and PR-negative tumors. Of note, 35% of triple-negative tumors displayed AR positivity. AR emerges as a promising marker in breast cancers, particularly in triple-negative cases. Larger-scale studies are warranted to comprehensively assess the relationship between AR expression and histopathological parameters, as well as other immunohistochemical markers.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"15 4","pages":"789-795"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right Ventricular Extrinsic Compression Tamponade Caused by Dilation/Necrosis of a Coloplasty Performed for Esophageal Squamous Cell Carcinoma.","authors":"Sébastien Tanaka, Tigran Poghosyan, Philippe Montravers","doi":"10.1007/s13193-024-02044-3","DOIUrl":"10.1007/s13193-024-02044-3","url":null,"abstract":"<p><p>In the context of dysphagia, an infiltrating squamous cell carcinoma of the esophagus was diagnosed in a 43-year-old woman with a history of two liver and one kidney transplants as a result of Alagille syndrome. An esophagectomy with retrosternal left coloplasty (esocolic, gastrocolic, and colocolic anastomoses) was performed. On postoperative day 2, her hemodynamic status deteriorated resulting in significant increases in norepinephrine doses (from 0.33 to 2 micg/kg/min). Transthoracic echocardiography was difficult to perform because the patient had limited imaging windows. Transesophageal echocardiography was contraindicated due to the nature of her surgery. An emergency thoraco-abdominal CT scan showed that the coloplasty was dilated, ischemic, and compressing the right ventricle anteriorly. Emergency surgery revealed mediastinitis with necrosis of the coloplasty. Surgical decompression of the coloplasty led to rapid improvement in hemodynamics, requiring only reduced doses of norepinephrine.</p>","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"15 4","pages":"746-747"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive Mole with Rare Ovarian Metastasis: Successful Treatment with Hysterectomy and Chemotherapy-A Case Report.","authors":"Geet Bhuyan, Manish Das","doi":"10.1007/s13193-024-02086-7","DOIUrl":"10.1007/s13193-024-02086-7","url":null,"abstract":"","PeriodicalId":46707,"journal":{"name":"Indian Journal of Surgical Oncology","volume":"15 Suppl 4","pages":"622-626"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11846799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}