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Promise and peril: doxycycline prophylaxis and the spread of resistance among diverse populations. 希望与危险：多西环素预防和耐药性在不同人群中的传播。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-22 DOI: 10.1016/j.lanmic.2025.101222
Michael E DeWitt, Jennifer J Wenner, Brinkley R Bellotti, Joshua A Manuel, Cindy Toler, Elizabeth Palavecino, Candice J McNeil
{"title":"Promise and peril: doxycycline prophylaxis and the spread of resistance among diverse populations.","authors":"Michael E DeWitt, Jennifer J Wenner, Brinkley R Bellotti, Joshua A Manuel, Cindy Toler, Elizabeth Palavecino, Candice J McNeil","doi":"10.1016/j.lanmic.2025.101222","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101222","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101222"},"PeriodicalIF":20.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zoonotic infections due to avian Chlamydia abortus: what are we missing? 由禽流产衣原体引起的人畜共患感染：我们错过了什么？
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-20 DOI: 10.1016/j.lanmic.2025.101197
Nicole Borel, David Longbottom, Gilbert Greub, Sarah Albini, Daisy Vanrompay, Karine Laroucau
{"title":"Zoonotic infections due to avian Chlamydia abortus: what are we missing?","authors":"Nicole Borel, David Longbottom, Gilbert Greub, Sarah Albini, Daisy Vanrompay, Karine Laroucau","doi":"10.1016/j.lanmic.2025.101197","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101197","url":null,"abstract":"<p><p>Chlamydia abortus is an obligate intracellular bacterium primarily affecting ruminants and causing reproductive failures in sheep and goats. As a recognised zoonotic pathogen, C abortus can cause obstetric and respiratory infections in humans, with severe consequences in pregnant women and immunocompromised individuals. Previous studies have identified novel C abortus strains in avian species, closely related to the zoonotic Chlamydia psittaci, with some strains associated with cases of human pneumonia. In this Personal View, we review the evolving taxonomy of C abortus in light of these novel avian strains, propose subspecies distinctions, and describe the different zoonotic risks associated with both avian and ruminant strains. Challenges in diagnostics, host preference, and case detection are discussed, emphasising the need for a One Health approach to fully understand and mitigate these risks. With increasing reports of human C abortus infections, precise strain classification and differentiation between avian and ruminant subspecies, along with targeted surveillance, are essential to limit their zoonotic transmission.</p>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101197"},"PeriodicalIF":20.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is there really a need for another global body for pandemic preparedness? 是否真的需要另一个全球性的大流行防范机构？
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-19 DOI: 10.1016/j.lanmic.2025.101216
Nelson Aghogho Evaborhene, Jessica Oreoluwa Oga, Chizaram Onyeaghala
{"title":"Is there really a need for another global body for pandemic preparedness?","authors":"Nelson Aghogho Evaborhene, Jessica Oreoluwa Oga, Chizaram Onyeaghala","doi":"10.1016/j.lanmic.2025.101216","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101216","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101216"},"PeriodicalIF":20.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the virological complexity and importance of One Health surveillance for zoonotic flaviviruses. 了解人畜共患黄病毒的病毒学复杂性和同一健康监测的重要性。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-19 DOI: 10.1016/j.lanmic.2025.101208
Annaleise R Howard-Jones, Dominic E Dwyer, Bart J Currie, Jen Kok
{"title":"Understanding the virological complexity and importance of One Health surveillance for zoonotic flaviviruses.","authors":"Annaleise R Howard-Jones, Dominic E Dwyer, Bart J Currie, Jen Kok","doi":"10.1016/j.lanmic.2025.101208","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101208","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101208"},"PeriodicalIF":20.4,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A layered strategy for tackling antimicrobial resistance: the Swiss cheese model for policy, prevention, and engagement. 应对抗菌素耐药性的分层战略：政策、预防和参与的瑞士奶酪模式。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-15 DOI: 10.1016/j.lanmic.2025.101215
Elias Mossialos, Sabiha Essack, Ian Mackay, Michael Anderson
{"title":"A layered strategy for tackling antimicrobial resistance: the Swiss cheese model for policy, prevention, and engagement.","authors":"Elias Mossialos, Sabiha Essack, Ian Mackay, Michael Anderson","doi":"10.1016/j.lanmic.2025.101215","DOIUrl":"10.1016/j.lanmic.2025.101215","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101215"},"PeriodicalIF":20.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolution's double-edged sword: SARS-CoV-2 adaptation in HIV reveals nature's safety valve. 进化的双刃剑：艾滋病病毒对SARS-CoV-2的适应揭示了大自然的安全阀。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-06 DOI: 10.1016/j.lanmic.2025.101212
Shaolei Li, Yunze Niu, Jingyuan Ning
{"title":"Evolution's double-edged sword: SARS-CoV-2 adaptation in HIV reveals nature's safety valve.","authors":"Shaolei Li, Yunze Niu, Jingyuan Ning","doi":"10.1016/j.lanmic.2025.101212","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101212","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101212"},"PeriodicalIF":20.4,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Waiting for disaster: Australia's arboviral outbreak reveals inadequacies of surveillance systems. 等待灾难：澳大利亚虫媒病毒爆发暴露了监测系统的不足。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-04 DOI: 10.1016/j.lanmic.2025.101207
Keran Sun, Keqi Jia, Jingyuan Ning
{"title":"Waiting for disaster: Australia's arboviral outbreak reveals inadequacies of surveillance systems.","authors":"Keran Sun, Keqi Jia, Jingyuan Ning","doi":"10.1016/j.lanmic.2025.101207","DOIUrl":"https://doi.org/10.1016/j.lanmic.2025.101207","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":" ","pages":"101207"},"PeriodicalIF":20.4,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARS-CoV-2 origins: imperfect but clear evidence SARS-CoV-2的起源：不完善但明确的证据。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-01 DOI: 10.1016/j.lanmic.2025.101209
The Lancet Microbe
{"title":"SARS-CoV-2 origins: imperfect but clear evidence","authors":"The Lancet Microbe","doi":"10.1016/j.lanmic.2025.101209","DOIUrl":"10.1016/j.lanmic.2025.101209","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":"6 8","pages":"Article 101209"},"PeriodicalIF":20.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How can the gut microbiome be targeted to fight multidrug-resistant organisms? 肠道微生物群如何成为对抗多重耐药微生物的目标？
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-01 DOI: 10.1016/j.lanmic.2024.101063
Benjamin Davido MD PhD , Blair Merrick MBChB , Prof Ed Kuijper MD PhD , Nicolas Benech MD PhD , Lena M Biehl MD PhD , Silvia Corcione MD PhD , European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Host and Microbiota Interactions (ESGHAMI)
{"title":"How can the gut microbiome be targeted to fight multidrug-resistant organisms?","authors":"Benjamin Davido MD PhD ,&nbsp;Blair Merrick MBChB ,&nbsp;Prof Ed Kuijper MD PhD ,&nbsp;Nicolas Benech MD PhD ,&nbsp;Lena M Biehl MD PhD ,&nbsp;Silvia Corcione MD PhD ,&nbsp;European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Host and Microbiota Interactions (ESGHAMI)","doi":"10.1016/j.lanmic.2024.101063","DOIUrl":"10.1016/j.lanmic.2024.101063","url":null,"abstract":"<div><div>The rise of antimicrobial resistance presents a challenge to public health, undermines the efficacy of antibiotics, and compromises the management of infectious diseases. Gut colonisation by multidrug-resistant organisms, such as multidrug-resistant Enterobacterales and vancomycin-resistant enterococci, is associated with increased morbidity and mortality rates, as well as health-care costs. Of late, the role of the gut microbiome in combating colonisation by multidrug-resistant organisms, which could precede invasive infection, has garnered interest. Innovative interventions, including faecal microbiota transplantation, probiotics, phage therapy, and bacterial consortia, represent potential preventive or therapeutic options to counteract colonisation by multidrug-resistant organisms. In this Personal View, we have synthesised the current findings on these interventions and elucidated their potential as solutions to the crisis of antimicrobial resistance.</div></div>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":"6 8","pages":"Article 101063"},"PeriodicalIF":20.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UKHSA publishes updated guidance for C auris UKHSA发布了最新的C auris指南。
IF 20.4 1区 生物学
Lancet Microbe Pub Date : 2025-08-01 DOI: 10.1016/j.lanmic.2025.101151
Timothy Jesudason
{"title":"UKHSA publishes updated guidance for C auris","authors":"Timothy Jesudason","doi":"10.1016/j.lanmic.2025.101151","DOIUrl":"10.1016/j.lanmic.2025.101151","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":"6 8","pages":"Article 101151"},"PeriodicalIF":20.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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