Lancet Microbe最新文献

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State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus. 基于微生物组的生物标记物的现状与未来:多学科德尔菲共识。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-04 DOI: 10.1016/j.lanmic.2024.07.011
Julie Rodriguez, Zahra Hassani, Carolina Alves Costa Silva, Fay Betsou, Federica Carraturo, Alessio Fasano, Mads Israelsen, Anandhi Iyappan, Aleksander Krag, Amira Metwaly, Robert Schierwagen, Jonel Trebicka, Hub Zwart, Joel Doré, Magali Cordaillat-Simmons, Celine Druart
{"title":"State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus.","authors":"Julie Rodriguez, Zahra Hassani, Carolina Alves Costa Silva, Fay Betsou, Federica Carraturo, Alessio Fasano, Mads Israelsen, Anandhi Iyappan, Aleksander Krag, Amira Metwaly, Robert Schierwagen, Jonel Trebicka, Hub Zwart, Joel Doré, Magali Cordaillat-Simmons, Celine Druart","doi":"10.1016/j.lanmic.2024.07.011","DOIUrl":"https://doi.org/10.1016/j.lanmic.2024.07.011","url":null,"abstract":"<p><p>Although microbiome signatures have been identified in various contexts (ie, pathogenesis of non-communicable diseases and treatment response), qualified microbiome-based biomarkers are currently not in use in clinical practice. The Human Microbiome Action consortium initiated a Delphi survey to establish a consensus on the needs, challenges, and limitations in developing qualified microbiome-based biomarkers. The questionnaire was developed by a scientific committee via literature review and expert interviews. To ensure broad applicability of the results, 307 experts were invited to participate; 114 of them responded to the first round of the survey, 93 of whom completed the second and final round as well. The survey highlighted the experts' confidence in the potential of microbiome-based biomarkers for several indications or pathologies. The paucity of validated analytical methods appears to be the principal factor hindering the qualification of these biomarkers. The survey also showed that clinical implementation of these biomarkers would only be possible if kitted and validated molecular assays with simple interpretation are developed. This initiative serves as a foundation for designing and implementing public-private collaborative projects to overcome the challenges and promote clinical application of microbiome-based biomarkers.</p>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First self-test for hepatitis C virus. 首次丙型肝炎病毒自我检测。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-03 DOI: 10.1016/j.lanmic.2024.100979
Priya Venkatesan
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引用次数: 0
Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study 新加坡第六个念珠菌支系的检测和特征:基因组和表型研究。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00101-0
Chayaporn Suphavilai PhD , Karrie Kwan Ki Ko MD , Kar Mun Lim BSc , Mei Gie Tan MSc , Patipan Boonsimma BSc , Joash Jun Keat Chu BSc , Sui Sin Goh MSc , Prevena Rajandran BSc , Lai Chee Lee MPH , Kwee Yuen Tan MSc , Bushra Binte Shaik Ismail MSc , May Kyawt Aung MPH , Yong Yang PhD , Jean Xiang Ying Sim MBBS , Indumathi Venkatachalam MBBS , Benjamin Pei Zhi Cherng MBBS , Bram Spruijtenburg BSc , Kian Sing Chan MBBS , Lynette Lin Ean Oon MBBS , Ai Ling Tan MBBS , Niranjan Nagarajan PhD
{"title":"Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study","authors":"Chayaporn Suphavilai PhD ,&nbsp;Karrie Kwan Ki Ko MD ,&nbsp;Kar Mun Lim BSc ,&nbsp;Mei Gie Tan MSc ,&nbsp;Patipan Boonsimma BSc ,&nbsp;Joash Jun Keat Chu BSc ,&nbsp;Sui Sin Goh MSc ,&nbsp;Prevena Rajandran BSc ,&nbsp;Lai Chee Lee MPH ,&nbsp;Kwee Yuen Tan MSc ,&nbsp;Bushra Binte Shaik Ismail MSc ,&nbsp;May Kyawt Aung MPH ,&nbsp;Yong Yang PhD ,&nbsp;Jean Xiang Ying Sim MBBS ,&nbsp;Indumathi Venkatachalam MBBS ,&nbsp;Benjamin Pei Zhi Cherng MBBS ,&nbsp;Bram Spruijtenburg BSc ,&nbsp;Kian Sing Chan MBBS ,&nbsp;Lynette Lin Ean Oon MBBS ,&nbsp;Ai Ling Tan MBBS ,&nbsp;Niranjan Nagarajan PhD","doi":"10.1016/S2666-5247(24)00101-0","DOIUrl":"10.1016/S2666-5247(24)00101-0","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;The emerging fungal pathogen &lt;em&gt;Candida auris&lt;/em&gt; poses a serious threat to global public health due to its worldwide distribution, multidrug resistance, high transmissibility, propensity to cause outbreaks, and high mortality. We aimed to characterise three unusual &lt;em&gt;C auris&lt;/em&gt; isolates detected in Singapore, and to determine whether they constitute a novel clade distinct from all previously known &lt;em&gt;C auris&lt;/em&gt; clades (I–V).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;In this genotypic and phenotypic study, we characterised three &lt;em&gt;C auris&lt;/em&gt; clinical isolates, which were cultured from epidemiologically unlinked inpatients at a large tertiary hospital in Singapore. The index isolate was detected in April, 2023. We performed whole-genome sequencing (WGS) and obtained hybrid assemblies of these &lt;em&gt;C auris&lt;/em&gt; isolates. The complete genomes were compared with representative genomes of all known &lt;em&gt;C auris&lt;/em&gt; clades. To provide a global context, 3651 international WGS data from the National Center for Biotechnology Information (NCBI) database were included in a high-resolution single nucleotide polymorphism (SNP) analysis. Antifungal susceptibility testing was done and antifungal resistance genes, mating-type locus, and chromosomal rearrangements were characterised from the WGS data of the three investigated isolates. We further implemented Bayesian logistic regression models to classify isolates into known clades and simulate the automatic detection of isolates belonging to novel clades as their WGS data became available.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;p&gt;The three investigated isolates were separated by at least 37 000 SNPs (range 37 000–236 900) from all existing &lt;em&gt;C auris&lt;/em&gt; clades. These isolates had opposite mating-type allele and different chromosomal rearrangements when compared with their closest clade IV relatives. The isolates were susceptible to all tested antifungals. Therefore, we propose that these isolates represent a new clade of &lt;em&gt;C auris,&lt;/em&gt; clade VI. Furthermore, an independent WGS dataset from Bangladesh, accessed via the NCBI Sequence Read Archive, was found to belong to this new clade. As a proof-of-concept, our Bayesian logistic regression model was able to flag these outlier genomes as a potential new clade.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Interpretation&lt;/h3&gt;&lt;p&gt;The discovery of a new &lt;em&gt;C auris&lt;/em&gt; clade in Singapore and Bangladesh in the Indomalayan zone, showing a close relationship to clade IV members most commonly found in South America, highlights the unknown genetic diversity and origin of &lt;em&gt;C auris&lt;/em&gt;, particularly in under-resourced regions. Active surveillance in clinical settings, along with effective sequencing strategies and downstream analysis, will be essential in the identification of novel strains, tracking of transmission, and containment of adverse clinical effects of &lt;em&gt;C auris&lt;/em&gt; infections.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Funding&lt;/h3&gt;&lt;p&gt;Duke-NUS Academic Medical Center Nurturing Cl","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724001010/pdfft?md5=0066d8cd1c31db4feb85fd8b229654f1&pid=1-s2.0-S2666524724001010-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To vaccinate or not against highly pathogenic avian influenza? 接种还是不接种高致病性禽流感疫苗?
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00107-1
{"title":"To vaccinate or not against highly pathogenic avian influenza?","authors":"","doi":"10.1016/S2666-5247(24)00107-1","DOIUrl":"10.1016/S2666-5247(24)00107-1","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724001071/pdfft?md5=0460eae2fc132680c775001d030173bc&pid=1-s2.0-S2666524724001071-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harmonising the measurement of neutralising antibodies against chikungunya virus: a path forward for licensing of new vaccines? 统一基孔肯雅病毒中和抗体的测量方法:新疫苗许可的前进之路?
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00097-1
{"title":"Harmonising the measurement of neutralising antibodies against chikungunya virus: a path forward for licensing of new vaccines?","authors":"","doi":"10.1016/S2666-5247(24)00097-1","DOIUrl":"10.1016/S2666-5247(24)00097-1","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000971/pdfft?md5=6c1c52597c47530e515792ccb5212867&pid=1-s2.0-S2666524724000971-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: results from two observational, population-based microbiome studies 产生丁酸盐的肠道细菌与传染病住院风险之间的关系:两项基于人群的观察性微生物组研究的结果。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00079-X
{"title":"Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: results from two observational, population-based microbiome studies","authors":"","doi":"10.1016/S2666-5247(24)00079-X","DOIUrl":"10.1016/S2666-5247(24)00079-X","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;Microbiota alterations are common in patients hospitalised for severe infections, and preclinical models have shown that anaerobic butyrate-producing gut bacteria protect against systemic infections. However, the relationship between microbiota disruptions and increased susceptibility to severe infections in humans remains unclear. We investigated the relationship between gut microbiota and the risk of future infection-related hospitalisation in two large population-based cohorts.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;In this observational microbiome study, gut microbiota were characterised using 16S rRNA gene sequencing in independent population-based cohorts from the Netherlands (HELIUS study; derivation cohort) and Finland (FINRISK 2002 study; validation cohort). HELIUS was conducted in Amsterdam, Netherlands, and included adults (aged 18–70 years at inclusion) who were randomly sampled from the municipality register of Amsterdam. FINRISK 2002 was conducted in six regions in Finland and is a population survey that included a random sample of adults (aged 25–74 years). In both cohorts, participants completed questionnaires, underwent a physical examination, and provided a faecal sample at inclusion (Jan 3, 2013, to Nov 27, 2015, for HELIUS participants and Jan 21 to April 19, 2002, for FINRISK participants. For inclusion in our study, a faecal sample needed to be provided and successfully sequenced, and national registry data needed to be available. Primary predictor variables were microbiota composition, diversity, and relative abundance of butyrate-producing bacteria. Our primary outcome was hospitalisation or mortality due to any infectious disease during 5–7-year follow-up after faecal sample collection, based on national registry data. We examined associations between microbiota and infection risk using microbial ecology and Cox proportional hazards.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;p&gt;We profiled gut microbiota from 10 699 participants (4248 [39·7%] from the derivation cohort and 6451 [60·3%] from the validation cohort). 602 (5·6%) participants (152 [3·6%] from the derivation cohort; 450 [7·0%] from the validation cohort) were hospitalised or died due to infections during follow-up. Gut microbiota composition of these participants differed from those without hospitalisation for infections (derivation p=0·041; validation p=0·0002). Specifically, higher relative abundance of butyrate-producing bacteria was associated with a reduced risk of hospitalisation for infections (derivation cohort cause-specific hazard ratio 0·75 [95% CI 0·60–0·94] per 10% increase in butyrate producers, p=0·013; validation cohort 0·86 [0·77–0·96] per 10% increase, p=0·0077). These associations remained unchanged following adjustment for demographics, lifestyle, antibiotic exposure, and comorbidities.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Interpretation&lt;/h3&gt;&lt;p&gt;Gut microbiota composition, specifically colonisation with butyrate-producing bacteria, was associated with","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266652472400079X/pdfft?md5=fd2df1ffc0f7c117acb299cdf1ceffdd&pid=1-s2.0-S266652472400079X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MERS-CoV exposure and risk factors for MERS-CoV ELISA seropositivity among members of livestock-owning households in southern Jordan: a population based cross-sectional study 约旦南部畜牧业户成员的 MERS-CoV 暴露和 MERS-CoV ELISA 血清阳性的风险因素:一项基于人口的横断面研究。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00082-X
Peter M Holloway PhD , Matthew D Gibson MSc , Tanja T Holloway MD , Neeltje van Doremalen PhD , Vincent J Munster PhD , Bilal Al-Omari BSc , Michael C Letko PhD , Stephen Nash MSc , Jacqueline M Cardwell PhD , Prof Ehab A Abu-Basha PhD , Prof Wail Hayajneh PhD , Prof Punam Mangtani PhD , Prof Javier Guitian PhD
{"title":"MERS-CoV exposure and risk factors for MERS-CoV ELISA seropositivity among members of livestock-owning households in southern Jordan: a population based cross-sectional study","authors":"Peter M Holloway PhD ,&nbsp;Matthew D Gibson MSc ,&nbsp;Tanja T Holloway MD ,&nbsp;Neeltje van Doremalen PhD ,&nbsp;Vincent J Munster PhD ,&nbsp;Bilal Al-Omari BSc ,&nbsp;Michael C Letko PhD ,&nbsp;Stephen Nash MSc ,&nbsp;Jacqueline M Cardwell PhD ,&nbsp;Prof Ehab A Abu-Basha PhD ,&nbsp;Prof Wail Hayajneh PhD ,&nbsp;Prof Punam Mangtani PhD ,&nbsp;Prof Javier Guitian PhD","doi":"10.1016/S2666-5247(24)00082-X","DOIUrl":"10.1016/S2666-5247(24)00082-X","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;p&gt;Although dromedary camels (&lt;em&gt;Camelus dromedarius&lt;/em&gt;) are known to be the host reservoir for MERS-CoV, the virus causing Middle East respiratory syndrome (MERS), zoonotic transmission pathways and camel subpopulations posing highest transmission risk are poorly understood. Extensively managed herds, ubiquitous across the Arabian Peninsula, present a major potential source of primary infection. In this study we aimed to address key knowledge gaps regarding MERS epidemiology among high-risk communities associated with such herds, which is essential information for effective control strategies.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;We did a cross-sectional study between Sept 27, 2017, and Oct 11, 2018, among members of livestock-owning households in southern Jordan (Aqaba East, Aqaba West, Ma’an East, and Ma’an West regions), with random selection of households (house and tent dwellings) from Ministry of Agriculture lists via computer-generated randomisation lists. Household visits were done, with questionnaires administered to household members regarding potential risk factors for MERS-CoV exposure in the past 6 months and blood samples and nasal and oral swabs collected, alongside physical examination data including blood pressure and blood glucose. Children younger than 5 years and individuals without capacity to provide informed consent were excluded. Serum was tested for IgG antibodies to MERS-CoV spike protein (S1 subunit) and nucleocapsid (N) protein with in-house indirect ELISAs, and viral RNA was detected in nasal and oral samples by RT-PCR. The primary outcome was evidence of MERS-CoV exposure (ascertained by seropositive status on S1 or N ELISAs, or a positive swab sample on RT-PCR); secondary outcomes were potential associations between possible risk factors and seropositive status. RT-PCR data were to be presented descriptively. Seroprevalence estimates were obtained at the individual and household levels, and associations between hypothetical risk factors and seropositive status were assessed with use of mixed-effects logistic regression.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Findings&lt;/h3&gt;&lt;p&gt;We sampled 879 household members (median age 27 years [IQR 16–44]; 471 [54%] males and 408 [46%] females) from 204 households. 72 (8%) household members were seropositive on S1 ELISA (n=25, 3%) or N ELISA (n=52, 6%). No positive nasal or oral swab samples were identified on RT-PCR. Within-household clustering was identified for seropositivity on S1 ELISA (intraclass correlation coefficient 0·88 [0·35–0·96]) but not N ELISA (0·00 [0·00–0·27]). On multivariable analysis, S1 ELISA seropositivity was associated with frequently (≥weekly) interacting with young (age &lt;1 year) camels (adjusted odds ratio [OR&lt;sub&gt;adj&lt;/sub&gt;] 3·85 [95% CI 1·41–11·61], p=0·011), with frequent kissing and petting (OR&lt;sub&gt;adj&lt;/sub&gt; 4·56 [1·55–15·42], p=0·0074), and frequent feeding and watering (OR&lt;sub&gt;adj&lt;/sub&gt; 4·97 [1·80–15·29], p=0·0027) of young camels identified as ","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266652472400082X/pdfft?md5=4e23a680a4d80620594bd79b719e967b&pid=1-s2.0-S266652472400082X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Candida auris: new clade, same challenges 白色念珠菌:新的支系,同样的挑战。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/j.lanmic.2024.100977
The Lancet Microbe
{"title":"Candida auris: new clade, same challenges","authors":"The Lancet Microbe","doi":"10.1016/j.lanmic.2024.100977","DOIUrl":"10.1016/j.lanmic.2024.100977","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724002386/pdfft?md5=60b4b15fe34e21b7499564e96d19ae1c&pid=1-s2.0-S2666524724002386-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Whole-genome sequencing unveils the outbreak of Mycoplasma pneumoniae in mainland China 全基因组测序揭示了肺炎支原体在中国大陆的爆发。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00086-7
{"title":"Whole-genome sequencing unveils the outbreak of Mycoplasma pneumoniae in mainland China","authors":"","doi":"10.1016/S2666-5247(24)00086-7","DOIUrl":"10.1016/S2666-5247(24)00086-7","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000867/pdfft?md5=8f8393c4d679784a95d437b3aa9237c7&pid=1-s2.0-S2666524724000867-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbiology Society Annual Conference 2024 微生物学会 2024 年年会。
IF 20.9 1区 生物学
Lancet Microbe Pub Date : 2024-09-01 DOI: 10.1016/S2666-5247(24)00167-8
{"title":"Microbiology Society Annual Conference 2024","authors":"","doi":"10.1016/S2666-5247(24)00167-8","DOIUrl":"10.1016/S2666-5247(24)00167-8","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724001678/pdfft?md5=7ef5254426e21780f31a33e3e8246083&pid=1-s2.0-S2666524724001678-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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