Lancet Microbe最新文献

{"title":"Stability of Bas-Congo virus neutralising antibodies in serum samples during long-term storage.","authors":"Yanlong Cong, Yibo Zhao, Lifeng Zhao, Yongzhi Wang, Fangyu Zhang, Jinghui Zhao","doi":"10.1016/S2666-5247(24)00156-3","DOIUrl":"https://doi.org/10.1016/S2666-5247(24)00156-3","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the risk of global spread of Neisseria meningitidis: strategies for the forthcoming 2024 Hajj following cases in the UK, France, and the USA.","authors":"Ziad A Memish, Alimuddin Zumla","doi":"10.1016/S2666-5247(24)00148-4","DOIUrl":"https://doi.org/10.1016/S2666-5247(24)00148-4","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":20.9,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resurgence of Mycoplasma pneumonia by macrolide-resistant epidemic clones in China","authors":"Heng Li , Shengkai Li , Huajiang Yang , Zhengrong Chen , Zhemin Zhou","doi":"10.1016/S2666-5247(23)00405-6","DOIUrl":"10.1016/S2666-5247(23)00405-6","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524723004056/pdfft?md5=0c5dc2d9030d0fabfbdda3905232daca&pid=1-s2.0-S2666524723004056-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive examination of travel-related antimicrobial resistance and the gut microbiome","authors":"Yu Sun , Xi Fu","doi":"10.1016/S2666-5247(24)00020-X","DOIUrl":"10.1016/S2666-5247(24)00020-X","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266652472400020X/pdfft?md5=341d4b78bb98d0fcd8181af83f55d7d6&pid=1-s2.0-S266652472400020X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139876891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multicentre, cross-sectional surveillance of Helicobacter pylori prevalence and antibiotic resistance to clarithromycin and levofloxacin in urban China using the string test coupled with quantitative PCR","authors":"Liang Wang , Zhengkang Li , Chin Yen Tay , Barry J Marshall , Bing Gu","doi":"10.1016/S2666-5247(24)00027-2","DOIUrl":"10.1016/S2666-5247(24)00027-2","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000272/pdfft?md5=ba5ea8a2a0d9952e932e56be10d8fc55&pid=1-s2.0-S2666524724000272-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xpert MTB/RIF Ultra versus mycobacterial growth indicator tube liquid culture for detection of Mycobacterium tuberculosis in symptomatic adults: a diagnostic accuracy study","authors":"Yingda L Xie MD ,&nbsp;Christie Eichberg BS ,&nbsp;Nchimunya Hapeela MPhil ,&nbsp;Elizabeth Nakabugo BSc ,&nbsp;Irene Anyango BSN ,&nbsp;Kiranjot Arora MPH ,&nbsp;Jeffrey E Korte PhD ,&nbsp;Ronald Odero BSc ,&nbsp;Judi van Heerden MSc ,&nbsp;Widaad Zemanay PhD ,&nbsp;Samuel Kennedy MPH ,&nbsp;Pamela Nabeta MD ,&nbsp;Mahmud Hanif PhD ,&nbsp;Camilla Rodrigues MD ,&nbsp;Alena Skrahina MD ,&nbsp;Wendy Stevens MBBCh ,&nbsp;Reynaldo Dietze MD ,&nbsp;Xin Liu MD ,&nbsp;Jerrold J Ellner MD ,&nbsp;David Alland MD ,&nbsp;Susan E Dorman MD","doi":"10.1016/S2666-5247(24)00001-6","DOIUrl":"10.1016/S2666-5247(24)00001-6","url":null,"abstract":"<div><h3>Background</h3><p>Xpert MTB/RIF Ultra (Ultra) is an automated molecular test for the detection of <em>Mycobacterium tuberculosis</em> in sputum. We compared the sensitivity of Ultra to that of mycobacterial growth indicator tube (MGIT) liquid culture, considered the most sensitive assay in routine clinical use.</p></div><div><h3>Methods</h3><p>In this prospective, multicentre, cross-sectional diagnostic accuracy study, we used a non-inferiority design to assess whether the sensitivity of a single Ultra test was non-inferior to that of a single liquid culture for detection of <em>M tuberculosis</em> in sputum. We enrolled adults (age ≥18 years) with pulmonary tuberculosis symptoms in 11 countries and each adult provided three sputum specimens with a minimum volume of 2 mL over 2 days. Ultra was done directly on sputum 1, and Ultra and MGIT liquid culture were done on resuspended pellet from sputum 2. Results of MGIT and solid media cultures done on sputum 3 were considered the reference standard. The pre-defined non-inferiority margin was 5·0%.</p></div><div><h3>Findings</h3><p>Between Feb 18, 2016, and Dec 4, 2019, we enrolled 2906 participants. 2600 (89%) participants were analysed, including 639 (25%) of 2600 who were positive for tuberculosis by the reference standard. Of the 2357 included in the non-inferiority analysis, 877 (37%) were HIV-positive and 984 (42%) were female. Sensitivity of Ultra performed directly on sputum 1 was non-inferior to that of sputum 2 MGIT culture (MGIT 91·1% <em>vs</em> Ultra 91·9%; difference –0·8 percentage points; 95% CI –2·8 to 1·1). Sensitivity of Ultra performed on sputum 2 pellet was also non-inferior to that of sputum 2 MGIT (MGIT 91·1% <em>vs</em> Ultra 91·9%; difference –0·8 percentage points; –2·7 to 1·0).</p></div><div><h3>Interpretation</h3><p>For the detection of <em>M tuberculosis</em> in sputum from adults with respiratory symptoms, there was no difference in sensitivity of a single Ultra test to that of a single MGIT culture. Highly sensitive, rapid molecular approaches for <em>M tuberculosis</em> detection, combined with advances in genotypic methods for drug resistance detection, have potential to replace culture.</p></div><div><h3>Funding</h3><p>US National Institute of Allergy and Infectious Diseases.</p></div>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000016/pdfft?md5=81eee41110e9a23256b7f47e2685347f&pid=1-s2.0-S2666524724000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumonia outbreaks due to re-emergence of Mycoplasma pneumoniae","authors":"Patrick M Meyer Sauteur ,&nbsp;Michael L Beeton","doi":"10.1016/S2666-5247(23)00406-8","DOIUrl":"10.1016/S2666-5247(23)00406-8","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524723004068/pdfft?md5=f52f8862dbdd1741d1e35d1cf05970ac&pid=1-s2.0-S2666524723004068-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139717887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Routine malaria vaccinations start in Africa","authors":"Priya Venkatesan","doi":"10.1016/S2666-5247(24)00073-9","DOIUrl":"10.1016/S2666-5247(24)00073-9","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000739/pdfft?md5=83561dc8652d04b0cadd4bfeda48cf09&pid=1-s2.0-S2666524724000739-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of Bas-Congo virus in Mangala, Democratic Republic of the Congo: a population-based cross-sectional study","authors":"Yannick Munyeku-Bazitama MTM ,&nbsp;Patient Okitale-Talunda MD ,&nbsp;Takanari Hattori PhD ,&nbsp;Takeshi Saito PhD ,&nbsp;Prof Boniface Pongombo Lombe PhD ,&nbsp;Hiroko Miyamoto DVM ,&nbsp;Akina Mori-Kajihara DVM ,&nbsp;Prof Masahiro Kajihara PhD ,&nbsp;Agathe Bikupe Nkoy MD ,&nbsp;Augustin Tshibwabwa Twabela PhD ,&nbsp;Prof Justin Masumu PhD ,&nbsp;Prof Steve Ahuka-Mundeke PhD ,&nbsp;Prof Jean-Jacques Muyembe-Tamfum PhD ,&nbsp;Prof Manabu Igarashi PhD ,&nbsp;Eun-sil Park PhD ,&nbsp;Prof Shigeru Morikawa PhD ,&nbsp;Prof Sheila Makiala-Mandanda PhD ,&nbsp;Prof Ayato Takada PhD","doi":"10.1016/S2666-5247(24)00021-1","DOIUrl":"10.1016/S2666-5247(24)00021-1","url":null,"abstract":"<div><h3>Background</h3><p>Bas-Congo virus (BASV), an emerging tibrovirus, was associated with an outbreak of acute haemorrhagic fever in Mangala, Democratic Republic of the Congo, in 2009. In 2012, neutralising antibodies to BASV were detected in the lone survivor and one of his close contacts. However, subsequent serological and molecular surveys were unsuccessful as neither BASV antibodies nor its RNA were detected. In this study, we determined the seroprevalence of BASV infection in Mangala 13 years after the initial outbreak.</p></div><div><h3>Methods</h3><p>We conducted a population-based serological survey from Jan 17 to Jan 23, 2022. Consenting individuals at least 5 years of age, living in Mangala for at least 4 weeks, and who had no contraindication to venepuncture were enrolled. Participants were interviewed using a pre-tested questionnaire for sociodemographic and clinical characteristics. We supplemented the collected serum samples with 284 archived samples from Matadi and Kinshasa. All samples were tested for antibodies to BASV and other tibroviruses using a pseudovirus-based neutralisation test.</p></div><div><h3>Findings</h3><p>Among the 267 individuals from Mangala, the prevalence of BASV antibodies was 55% (95% CI 49–61; n=147). BASV seropositivity odds significantly increased with age (5·2 [95% CI 2·1–12·9] to 83·9 [20·8–337·7] times higher in participants aged 20 years or older than participants aged 5–19 years). Some occupational categories (eg, farmer or public servant) were associated with seropositivity. Only nine (6%) of 160 samples from Matadi and one (&lt;1%) of 124 samples from Kinshasa had neutralising antibodies to BASV. Moreover, we also detected neutralising antibodies to other tibroviruses—Ekpoma virus 1, Ekpoma virus 2, and Mundri virus—in 84 (31%), 251 (94%), and 219 (82%) of 267 Mangala samples; 14 (9%), 62 (39%), and 120 (75%) of 160 Matadi samples; and six (5%), five (4%), and 33 (27%) of 124 Kinshasa samples, respectively.</p></div><div><h3>Interpretation</h3><p>Human infection with BASV and other tibroviruses seems common in Mangala, although no deadly outbreak has been reported since 2009. Exposure to BASV might be highly restricted to Mangala and the increasing prevalence of neutralising antibodies with age suggests regular contact with the virus in this city. Altogether, our findings suggest that human infection with tibroviruses could be common in the study areas and not associated with deadly haemorrhagic or debilitating syndromes.</p></div><div><h3>Funding</h3><p>Japan Agency for Medical Research and Development (AMED) and Japan International Cooperation Agency (JICA) under the Science and Technology Research Partnership for Sustainable Development (SATREPS) and Japan Program for Infectious Diseases Research and Infrastructure from AMED.</p></div>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724000211/pdfft?md5=a31690847eed6bc915246ad4ab616f90&pid=1-s2.0-S2666524724000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140332172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wastewater: between surveillance and intrusion","authors":"The Lancet Microbe","doi":"10.1016/S2666-5247(24)00132-0","DOIUrl":"10.1016/S2666-5247(24)00132-0","url":null,"abstract":"","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":null,"pages":null},"PeriodicalIF":38.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666524724001320/pdfft?md5=66664e7fa37efe1f617b02f69161d3e0&pid=1-s2.0-S2666524724001320-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}