Lancet Microbe最新文献_第5页

Analysis of H5N1 2.3.4.4b sublineage origins and K193 and N193 prevalence in human isolates. 分析 H5N1 2.3.4.4b 亚系起源以及 K193 和 N193 在人类分离物中的流行率。

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-06 DOI: 10.1016/j.lanmic.2025.101112

Amir Ghaemi, Nader Ebrahimi

引用次数: 0

Flying blind: urgency for drug-resistant testing for new tuberculosis drugs.

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-06 DOI: 10.1016/j.lanmic.2025.101106

Nicholas Quansah, Maria B Arriaga, Roger I Calderon, Sanghyuk Shin, Stephen Molldrem, Stefan Niemann, Cesar Ugarte-Gil

引用次数: 0

A case for global standardisation of genomics and wastewater-based epidemiology.

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-06 DOI: 10.1016/j.lanmic.2025.101092

Noemí Cajas-Corrales, Diana Vallejo-Espín, William Calero-Cáceres

引用次数: 0

The UK's antimicrobial resistance response faces substantial barriers from the civil service's structure, practices of governance, and churn.

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-06 DOI: 10.1016/j.lanmic.2025.101111

Paul-Enguerrand Fady, Natalie Bennett, Andrew Singer

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Interactions between bacteria in the human nasopharynx: a scoping review.

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-03 DOI: 10.1016/j.lanmic.2024.101062

Kan Yu, Vanessa Tenaglia, Eng Guan Chua, Robbie Haines, Girish Bahal, Mark P Nicol, Ritika Kar Bahal

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引用次数: 0

Implementing a national programme of pathogen genomics for public health: the Australian Pathogen Genomics Program (AusPathoGen) 实施国家公共卫生病原体基因组计划：澳大利亚病原体基因组计划（AusPathoGen）。

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-01 DOI: 10.1016/j.lanmic.2024.100969

Jessica R Webb PhD , Patiyan Andersson PhD , Eby Sim PhD , Alireza Zahedi PhD , Angela Donald MPH , Tuyet Hoang MPH , Anne E Watt PhD , Jessica E Agius PhD , Celeste M Donato PhD , Max L Cummins PhD , Tehzeeb Zulfiqar PhD , Son Nghiem PhD , Chantel Lin MPH , Dimitrios Menouhos BMLSc , Lex E X Leong PhD , Rob Baird MBBS FRCPA , Karina Kennedy MBBS , Louise Cooley MBBS , Prof David Speers MBBS , Chuan Kok Lim PhD , Benjamin P Howden MBBS PhD

{"title":"Implementing a national programme of pathogen genomics for public health: the Australian Pathogen Genomics Program (AusPathoGen)","authors":"Jessica R Webb PhD , Patiyan Andersson PhD , Eby Sim PhD , Alireza Zahedi PhD , Angela Donald MPH , Tuyet Hoang MPH , Anne E Watt PhD , Jessica E Agius PhD , Celeste M Donato PhD , Max L Cummins PhD , Tehzeeb Zulfiqar PhD , Son Nghiem PhD , Chantel Lin MPH , Dimitrios Menouhos BMLSc , Lex E X Leong PhD , Rob Baird MBBS FRCPA , Karina Kennedy MBBS , Louise Cooley MBBS , Prof David Speers MBBS , Chuan Kok Lim PhD , Benjamin P Howden MBBS PhD","doi":"10.1016/j.lanmic.2024.100969","DOIUrl":"10.1016/j.lanmic.2024.100969","url":null,"abstract":"<div><div>Delivering large-scale routine pathogen genomics surveillance for public health is of considerable interest, although translational research models that promote national-level implementation are not well defined. We describe the development and deployment of the Australian Pathogen Genomics Program (AusPathoGen), a comprehensive national partnership between academia, public health laboratories, and public health agencies that commenced in January, 2021. Successfully establishing and delivering a national programme requires inclusive and transparent collaboration between stakeholders, defined and clear focus on public health priorities, and support for strengthening national genomics capacity. Major enablers for delivering such a programme include technical solutions for data integration and analysis, such as the genomics surveillance platform AusTrakka, standard bioinformatic analysis methods, and national ethics and data sharing agreements that promote nationally integrated surveillance systems. Training of public health officials to interpret and act on genomic data is crucial, and evaluation and cost-effectiveness programmes will provide a benchmark and evidence for sustainable investment in genomics nationally and globally.</div></div>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":"6 3","pages":"Article 100969"},"PeriodicalIF":20.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing urgent priorities in antibiotic development: insights from WHO 2023 antibacterial clinical pipeline analyses 解决抗生素开发中的当务之急：世界卫生组织 2023 年抗菌药物临床管线分析的启示。

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-01 DOI: 10.1016/j.lanmic.2024.100992

Prof Daniela Melchiorri PhD , Tamarie Rocke MD , Richard A Alm PhD , Alexandra M Cameron PhD , Valeria Gigante PhD

{"title":"Addressing urgent priorities in antibiotic development: insights from WHO 2023 antibacterial clinical pipeline analyses","authors":"Prof Daniela Melchiorri PhD , Tamarie Rocke MD , Richard A Alm PhD , Alexandra M Cameron PhD , Valeria Gigante PhD","doi":"10.1016/j.lanmic.2024.100992","DOIUrl":"10.1016/j.lanmic.2024.100992","url":null,"abstract":"<div><div>Antimicrobial resistance continues to evolve and remains a leading cause of death worldwide, with children younger than 5 years being among those at the highest risk. Addressing antimicrobial resistance requires a comprehensive response, including infection prevention efforts, surveillance, stewardship, therapy appropriateness and access, and research and development. However, antimicrobial research and development is limited and lags behind the output of other fields, such as that of cancer or HIV research. The 2023 WHO analysis of the global antibacterial clinical pipeline serves as a tool to monitor and guide research and development efforts. The analysis emphasises the remaining gaps in developing a robust and effective antibacterial drug pipeline, drawing insights from trend analyses and assessment of the innovation potential of candidate antimicrobials. In the present analysis, we evaluated the activity of antibiotics against the new WHO bacterial priority pathogens list 2024, which reflects changing trends in resistance patterns, distribution of bacterial infections, and the emergence of new resistance mechanisms.</div></div>","PeriodicalId":46633,"journal":{"name":"Lancet Microbe","volume":"6 3","pages":"Article 100992"},"PeriodicalIF":20.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variability of Mycobacterium tuberculosis lipid body content in sputum and its implications for treatment response 痰中结核分枝杆菌脂质体含量的变化及其对治疗反应的影响。

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-01 DOI: 10.1016/j.lanmic.2024.101024

Mohamed Imath , Viswanathan Sathyanathan , Suresh Velayudam , R A M Jainaf Nachiya

引用次数: 0

Egypt declared malaria free 埃及宣布消灭疟疾。

IF 20.9 1区生物学

Lancet Microbe Pub Date : 2025-03-01 DOI: 10.1016/j.lanmic.2024.101052

Priya Venkatesan

引用次数: 0

Thank you to The Lancet Microbe statistical and peer reviewers in 2024