Asian Journal of Urology最新文献

{"title":"Determination of the kidney stone composition using infrared spectroscopy in Iran at a national referral center during 2019–2023","authors":"Abbas Basiri ,&nbsp;Azin Tahvildari ,&nbsp;Mohammad Naji,&nbsp;Pardis Ziaeefar,&nbsp;Amir H. Kashi","doi":"10.1016/j.ajur.2024.07.004","DOIUrl":"10.1016/j.ajur.2024.07.004","url":null,"abstract":"<div><h3>Objective</h3><div>The national lifetime prevalence of urolithiasis is estimated at 6.6% in Iran. However, reports on the composition of kidney stones have been based on imprecise methods like the chemical analysis. No prior large-scale study has reported the composition of kidney stones based on the gold-standard methods (X-ray diffraction or infrared spectroscopy) in Iran. This study aimed to provide the composition of kidney stones based on Fourier transform infrared spectroscopy.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study assessing urinary stone composition from various cities in Iran at a referral center using infrared spectroscopy from February 2019 to March 2023.</div></div><div><h3>Results</h3><div>This study determined the stone composition of 1092 patients from 10 cities in Iran. Overall, the majority of stones were composed of calcium oxalate (<em>n</em>=498; 45.6%) and uric acid (UA, <em>n</em>=488; 44.7%) followed by cystine (<em>n</em>=49; 4.5%) and struvite (<em>n</em>=28; 2.6%). Stone composition in Shiraz and Isfahan was roughly similar with a higher percentage of UA stones (53.4% and 53.6%, respectively) while the capital city of Iran (Tehran) had less frequent UA stones (39.9%) with a higher percentage of calcium oxalate stones. The percentage of UA stones increased with age as it was 11.1% in children, 42.7% in adults, and 83.3% in geriatric patients (<em>p</em>&lt;0.001). About 29.6% of cystine stones were observed in children.</div></div><div><h3>Conclusion</h3><div>The most frequent stone composition among kidney stones in Iran was calcium oxalate and UA stones. This relative frequency of UA stones is considerably higher than many international reports from neighboring as well as distant countries. More cystine stones were observed in children and women. Geriatric patients’ stones were mostly composed of UA.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 72-78"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An open-label, randomized, post-authorization study of mirabegron in Chinese participants with overactive bladder","authors":"Zhipeng Zhang ,&nbsp;Deyi Luo ,&nbsp;Zhong Chen ,&nbsp;Peng Zhang ,&nbsp;Ganping Zhong ,&nbsp;Keji Xie ,&nbsp;Zhuoqun Xu ,&nbsp;Xudong Li ,&nbsp;Jianye Wang ,&nbsp;Yingfan Yang ,&nbsp;Farid Abdul Hadi ,&nbsp;Arianne Schild","doi":"10.1016/j.ajur.2024.04.007","DOIUrl":"10.1016/j.ajur.2024.04.007","url":null,"abstract":"<div><h3>Objective</h3><div>To assess efficacy and safety of mirabegron 25 mg/day and 50 mg/day for overactive bladder in Chinese participants.</div></div><div><h3>Methods</h3><div>Participants of ≥18 years with overactive bladder symptoms lasting for ≥12 weeks, a mean of ≥8 micturitions per 24 h, and a mean of at least one episode of Grade 3 or 4 urgency or urge incontinence per 24 h based on the Patient Perception of Intensity of Urgency Scale over a 3-day micturition diary period were randomized 2:1 to open-label treatment with oral mirabegron 50 mg or 25 mg once daily for 12 weeks (15 sites in China, January 2021–March 2022). A dose escalation from 25 mg/day to 50 mg/day was permitted at weeks 4 and 8 according to the investigators' discretion. The primary efficacy endpoint was the change from baseline to Week 12 in the mean number of micturitions per 24 h in those randomized to mirabegron 50 mg/day. Secondary efficacy endpoints were the change in mean number of micturitions at weeks 4 and 8 in the mirabegron 50 mg/day group and weeks 4, 8, and 12 in the mirabegron 25 mg/day group, change from baseline to weeks 4, 8, and 12 in Grade 3 or 4 urgency episodes on the Patient Perception of Intensity of Urgency Scale, episodes of daytime incontinence, nighttime incontinence, and urgency incontinence, and Overactive Bladder Symptom Score for mirabegron 50 mg/day and 25 mg/day groups.</div></div><div><h3>Results</h3><div>Statistically significant reduction (<em>p</em>&lt;0.001) from baseline to Week 12 was observed in mean micturitions per 24 h for participants randomized to mirabegron 50 mg/day: mean±standard error: 11.71±0.43 at baseline, 7.80±0.24 at Week 12; adjusted mean change: −3.73 (95% confidence interval −4.30 to −3.16). Both doses showed statistically significant improvement in secondary efficacy endpoints at weeks 4, 8, and 12 versus baseline. Safety was consistent with mirabegron's known safety profile.</div></div><div><h3>Conclusion</h3><div>The results support a mirabegron dosage of 50 mg/day for the treatment of OAB in China.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 79-86"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indocyanine green-guided robotic-assisted partial cystectomy","authors":"Zhipeng Yao,&nbsp;Heng Li,&nbsp;Shen Wang,&nbsp;Fan Li,&nbsp;Jia Hu,&nbsp;Zheng Liu","doi":"10.1016/j.ajur.2024.01.005","DOIUrl":"10.1016/j.ajur.2024.01.005","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 129-130"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139636633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic value of the 8th American Joint Committee on cancer anatomic and prognostic stage groups for penile cancer: A multicenter collaboration study","authors":"Xueying Li ,&nbsp;Yepeng Guo ,&nbsp;Antonio Augusto Ornellas ,&nbsp;Jiun-Hung Geng ,&nbsp;Yonghong Li ,&nbsp;Wayne Lam ,&nbsp;Yabing Cao ,&nbsp;Zhuowei Liu ,&nbsp;Hui Han ,&nbsp;Fangjian Zhou ,&nbsp;Zaishang Li","doi":"10.1016/j.ajur.2024.10.001","DOIUrl":"10.1016/j.ajur.2024.10.001","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to investigate the value of the 8th American Joint Committee on Cancer (AJCC) anatomic and prognostic stage groups for penile cancer patients and explore whether there is room for improvement.</div></div><div><h3>Methods</h3><div>The clinical and histopathologic data from 16 centers between January 2000 and December 2021 were assessed according to the 8th AJCC anatomic and prognostic stage groups. Kaplan–Meier plots were used to estimate the disease-specific survival (DSS) of the patients. The accuracy of the staging systems was investigated using the Harrell's concordance index (C-index).</div></div><div><h3>Results</h3><div>According to the 8th AJCC anatomic and prognostic stage groups, the 5-year DSS rates for patients with stages 0is/a, I, IIA, IIB, IIIA, IIIB, and IV disease were 100%, 99%, 86%, 81%, 66%, 34%, and 23%, respectively (<em>p</em>_0is/a–I=0.8, <em>p</em>_I–IIA&lt;0.001, <em>p</em>_IIA–IIB=0.5, <em>p</em>_IIB–IIIA&lt;0.001, <em>p</em>_IIIA–IIIB&lt;0.001, <em>p</em>_IIIB–IV=0.004, and <em>p</em>_Total&lt;0.001). According to the modified model 1 system, the 5-year DSS rates without survivorship overlap for patients with stages 0is/a, I, II, IIIA, IIIB, and IV disease were 100%, 99%, 88%, 66%, 34%, and 23%, respectively (<em>p</em>_0is/a–I=0.8, <em>p</em>_I–II&lt;0.001, <em>p</em>_II–IIIA=0.002, <em>p</em>_IIIA–IIIB&lt;0.001, <em>p</em>_IIIB–IV=0.004, and <em>p</em>_Total&lt;0.001). Similarly, according to the modified model 2 system, the 5-year DSS rates without survivorship overlap for patients with stages 0is/a, I, II, IIIA, IIIB, and IV disease were 100%, 99%, 86%, 66%, 34%, and 23%, respectively (<em>p</em>_0is/a–I=0.8, <em>p</em>_I–II&lt;0.001, <em>p</em>_II–IIIA=0.008, <em>p</em>_IIIA–IIIB&lt;0.001, <em>p</em>_IIIB–IV=0.004, and <em>p</em>_Total&lt;0.001). The C-index scores of the simple modified staging systems were not inferior to those of the AJCC anatomic and prognostic stage groups. These results were confirmed by the bootstrap internal validation.</div></div><div><h3>Conclusion</h3><div>There is still room for improvement about the 8th AJCC anatomic and prognostic stage groups. The improved models, which are more concise and convenient, have similar prediction accuracy.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 100-105"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual case of blood dripping following robotic-assisted laparoscopic varicocelectomy","authors":"Ciro Esposito,&nbsp;Claudia Di Mento,&nbsp;Annalisa Chiodi,&nbsp;Giovanni Esposito,&nbsp;Luisa Florio,&nbsp;Maria Escolino","doi":"10.1016/j.ajur.2024.06.004","DOIUrl":"10.1016/j.ajur.2024.06.004","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 127-128"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The diagnostic performance of indocyanine green for the sentinel node biopsy in prostate cancer: A systematic review and meta-analysis","authors":"Siyang Ma ,&nbsp;Jianxuan Sun ,&nbsp;Jinzhou Xu,&nbsp;Ye An,&nbsp;Mengyao Xu,&nbsp;Chenqian Liu,&nbsp;Sihan Zhang,&nbsp;Lintao Miao,&nbsp;Xingyu Zhong,&nbsp;Na Zeng,&nbsp;Haodong He,&nbsp;Shaogang Wang,&nbsp;Qidong Xia","doi":"10.1016/j.ajur.2024.07.001","DOIUrl":"10.1016/j.ajur.2024.07.001","url":null,"abstract":"<div><h3>Objective</h3><div>Almost 15% of prostate cancer (PCa) patients were found to have lymph node metastases (LNMs), which are associated with higher risk of biochemical recurrence. Using indocyanine green (ICG) for the sentinel node biopsy (SNB) before surgery was proposed to detect LNMs in PCa patients. However, its diagnostic performance still remains controversial. This study aimed to investigate the diagnostic performance of ICG for the SNB in PCa.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis has been reported in line with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The protocol has been registered in the International Prospective Register of Systematic Reviews database, and the register number is CRD42023421911. Four bibliographic databases were searched, <em>i.e.</em>, PubMed, EMBASE, Cochrane Library, and Web of Science, to retrieve articles studying the diagnostic performance of ICG for the SNB in PCa from the inception to Sep 9, 2023. We calculated the pooled sensitivity, specificity, likelihood ratios, diagnostic odds ratios and their 95% confidence intervals (CIs). Subgroup analyses and meta-regression analyses were also conducted.</div></div><div><h3>Results</h3><div>A total of 17 articles from databases are enrolled in this study. Using lymph node-based data, our results showed that the pooled sensitivity and specificity of applying ICG alone in PCa were 71% (95% CI 52%–85%) and 68% (95% CI 64%–72%), respectively. The pooled sensitivity and specificity of applying ICG-technetium-99m-nanocolloid in PCa were 49% (95% CI 39%–59%) and 69% (95% CI 67%–71%), respectively.</div></div><div><h3>Conclusion</h3><div>The efficacy of using ICG or ICG-technetium-99m-nanocolloid for the SNB in PCa is relatively unsatisfactory. ICG cannot yet substitute extended pelvic lymph node dissection for detecting LNMs accurately. More research or novel tracers are needed to achieve the goal of precise surgery.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 1-14"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Worldwide variations in the knowledge and use of fluoroscopy during percutaneous nephrolithotomy—should we do better? A survey by the European Association of Urology Section for Uro-Technology and the International Alliance of Urolithiasis","authors":"Otaš Durutovic ,&nbsp;Guohua Zeng ,&nbsp;Bhaskar Somani ,&nbsp;Simon Choong ,&nbsp;Giorgio Mazzon ,&nbsp;Di Gu ,&nbsp;Zeeshan Hameed ,&nbsp;TP Rajeev ,&nbsp;Bogomir Milojevic ,&nbsp;Davide Brusa ,&nbsp;Tiago Ribeiro Oliveira ,&nbsp;Sergio Pereira ,&nbsp;Nariman Gadzhiev ,&nbsp;Ali Serdar Gozen ,&nbsp;Evangelos Liatsikos ,&nbsp;Panagiotis Kallidonis ,&nbsp;Uros Bumbasirevic ,&nbsp;Andreas Skolarikos","doi":"10.1016/j.ajur.2024.02.004","DOIUrl":"10.1016/j.ajur.2024.02.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the level of knowledge among urologists of usage of fluoroscopy during percutaneous nephrolithotomy.</div></div><div><h3>Methods</h3><div>We conducted an anonymous internet-based survey addressed to the EAU Section of Uro-Technology and the International Alliance of Urolithiasis members with particular interest in the stone treatment at all levels of expertise. The final version of the questionnaire included 31 questions, evaluated the level of knowledge on X-ray utilization and exposure, and identified correlations between geographic areas, levels of seniority, surgical volumes, and awareness on radiation protection.</div></div><div><h3>Results</h3><div>In total, 586 respondents were included. Knowledge of fluoroscopy settings appeared low, particularly among trainees (up to 87.5% were uninformed, <em>p</em>=0.008). Precautions to reduce exposure appeared poorly followed as up to 25.4% of respondents used regularly continuous fluoroscopy, and up to 20.5% used regularly high-frequency setting and this trend was more obvious among senior specialists (6.2% of trainees used high-frequency settings <em>vs.</em> 21.3% of consultants, <em>p</em>&lt;0.05). Additionally, only 24.9% of respondents would provide X-ray protection to patients too.</div></div><div><h3>Conclusion</h3><div>Although high and routinary utilization of X-rays, the level of awareness and adhesion to “as low as reasonably achievable” principles among endourologists seems suboptimal in 65.0% of all respondents. Highest volume surgeons, inevitably at higher risk, do not seem to adopt more precautions. More efforts should be addressed to improve these results, reducing the risk related to excessive radiation exposure for both surgical staff and patients in order to minimize health related issues.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 51-58"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140468859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketamine-associated upper urinary tract dysfunction: What we know from current literature","authors":"Zhihuan Zheng ,&nbsp;Zhongyi Li ,&nbsp;Jiazhe Yuan ,&nbsp;Feng Han ,&nbsp;Li Huang ,&nbsp;Zhao Wang","doi":"10.1016/j.ajur.2024.05.004","DOIUrl":"10.1016/j.ajur.2024.05.004","url":null,"abstract":"<div><h3>Objective</h3><div>To review the current literature on ketamine-associated upper urinary tract (UUT) dysfunction and provide an overview of its pathogenesis and treatment principles.</div></div><div><h3>Methods</h3><div>A literature search was conducted using PubMed and Cochrane databases for relevant articles published in English between 2008 and 2023. Keywords used included “ketamine” and “upper urinary tract”.</div></div><div><h3>Results</h3><div>A total of 22 papers were included. Relatively few studies have focused on ketamine-associated UUT dysfunction. Exclusion criteria included lack of hydronephrosis, or pathological findings. After careful screening and exclusion, we finally adopted 11 of these papers and analyzed them. Ketamine-associated UUT dysfunction may be a concern in this field.</div></div><div><h3>Conclusion</h3><div>Ketamine abuse can lead to UUT impairment and dysfunction, with symptoms such as bladder dysfunction and contracted bladder with vesicoureteral reflux, direct damage and barrier dysfunction, inflammation, apoptosis, fibrosis and stricture, and papillary necrosis. Oxidative stress, autophagy, and microvascular injury are also potential pathogenic mechanisms. The detection of these symptoms largely depends on laboratory and imaging examinations. The treatment principles of ketamine-associated UUT dysfunction are protecting the UUT, improving bladder dysfunction, and resuming normal social life. More investigations are needed to clarify the mechanisms and shed light on the treatment of ketamine-associated UUT damage.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 33-42"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of intravenous urography-assisted shockwave lithotripsy for radiolucent ureteral stones","authors":"Shinya Somiya ,&nbsp;Shigeki Koterazawa ,&nbsp;Katsuhiro Ito ,&nbsp;Takao Haitani ,&nbsp;Yuki Makino ,&nbsp;Ryuichiro Arakaki ,&nbsp;Norio Kawase ,&nbsp;Yoshihito Higashi ,&nbsp;Hitoshi Yamada ,&nbsp;Toru Kanno","doi":"10.1016/j.ajur.2024.03.002","DOIUrl":"10.1016/j.ajur.2024.03.002","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to compare the clinical outcomes of intravenous urography-assisted fluoroscopy-guided shockwave lithotripsy for radiolucent ureteral stones and standard shockwave lithotripsy for radiopaque ureteral stones.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed 734 patients with ureteral stones treated by fluoroscopy-guided shockwave lithotripsy between March 2014 and March 2021. The primary outcome was a stone-free rate with one session within 30 days, defined as no residual stones without auxiliary treatment. The multivariate analysis was used to examine whether the intravenous urography use predicted treatment success. Furthermore, we compared the outcomes using propensity score matching.</div></div><div><h3>Results</h3><div>Ninety-eight patients underwent the intravenous urography use protocol (Group I), and the remaining 636 patients underwent the non-intravenous urography protocol (Group N). Stone-free rates with one session within 30 days were 38% and 32% in groups I and N, respectively (<em>p</em>=0.3). No statistical differences were observed in the conversion rate to ureteroscopy (<em>p</em>=0.3) or complication rate (<em>p</em>=0.7) between Group I and Group N. One patient who developed skin redness was considered a complication of the contrast medium. Propensity score matching examined 88 matched pairs. Treatment success was obtained in 31 (35%) patients in Group I and 33 (38%) patients in Group N (<em>p</em>=0.9) within 30 days with one session.</div></div><div><h3>Conclusion</h3><div>Radiolucent stones can be safely and effectively treated by shockwave lithotripsy with intravenous urography.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 66-71"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the concordance between Vesical Imaging Reporting and Data System scores and bladder tumor histopathology","authors":"Hasan Gungor ,&nbsp;Ahmet Camtosun ,&nbsp;Ibrahim Topcu ,&nbsp;Leyla Karaca","doi":"10.1016/j.ajur.2024.06.001","DOIUrl":"10.1016/j.ajur.2024.06.001","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess the local staging of bladder tumors in patients utilizing preoperative multiparametric MRI (mpMRI) and to demonstrate the clinical efficacy of this method through a comparative analysis with corresponding histopathological findings.</div></div><div><h3>Methods</h3><div>Between November 2020 and April 2022, 63 patients with a planned cystoscopy and a preliminary or previous diagnosis of bladder tumor were included. All participants underwent mpMRI, and Vesical Imaging Reporting and Data System (VI-RADS) criteria were applied to assess the recorded images. Subsequently, obtained biopsies were histopathologically examined and compared with radiological findings.</div></div><div><h3>Results</h3><div>Of the 63 participants, 60 were male, and three were female. Categorizing tumors with a VI-RADS score of &gt;3 as muscle invasive, 84% were radiologically classified as having an invasive bladder tumor. However, histopathological results indicated invasive bladder tumors in 52% of cases. Sensitivity of the VI-RADS score was 100%; specificity was 23%; the negative predictive value was 100%; and the positive predictive value was 62%.</div></div><div><h3>Conclusion</h3><div>The scoring system obtained through mpMRI, VI-RADS, proves to be a successful method, particularly in determining the absence of muscle invasion in bladder cancer. Its efficacy in detecting muscle invasion in bladder tumors could be further enhanced with additional studies, suggesting potential for increased diagnostic efficiency through ongoing research. The VI-RADS could enhance the selection of patients eligible for accurate diagnosis and treatment.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 1","pages":"Pages 87-92"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}