Asian Journal of Urology最新文献

{"title":"Sono-urethrogram versus conventional urethrogram in the assessment of urethral stricture disease: A prospective comparative study","authors":"Akash Chitrakar,&nbsp;Baikuntha Adhikari,&nbsp;Udita Mishra,&nbsp;Arvind Kumar Shah,&nbsp;Robin Bahadur Basnet,&nbsp;Parash Mani Shrestha,&nbsp;Anil Shrestha","doi":"10.1016/j.ajur.2024.07.003","DOIUrl":"10.1016/j.ajur.2024.07.003","url":null,"abstract":"<div><h3>Objective</h3><div>The management of urethral stricture disease depends on the location, length of stricture, and associated urethral pathology. These parameters are obtained from preoperative imaging, with conventional urethrogram (retrograde urethrogram and micturating cystourethrogram [RGU/MCU]) being the diagnostic tool of choice despite its many shortcomings. Sono-urethrogram (SUG) is an alternative that addresses most issues of RGU/MCU. Studies comparing RGU/MCU with SUG are limited. With the objective of comparing these two imaging modalities in the evaluation of urethral stricture disease, a prospective study was conducted.</div></div><div><h3>Methods</h3><div>Fifty-six patients suspected of urethral stricture disease on clinical evaluation and confirmed either on RGU/MCU or urethro-cystoscopy were included in the study. SUG was performed by the experienced consultant radiologist who was blinded to the report of RGU/MCU. Findings of RGU/MCU and SUG were compared to intraoperative findings, which served as the reference standard.</div></div><div><h3>Results</h3><div>The median length of the stricture determined intraoperatively was 16.5 mm, by RGU/MCU was 5.8 mm, and by SUG was 13.5 mm. The diagnostic accuracy for determination of the stricture location was 93% for RGU/MCU and 98% for SUG. SUG identified spongiofibrosis in 90% of patients with higher accuracy for the severe degree of spongiofibrosis.</div></div><div><h3>Conclusion</h3><div>SUG has been shown to be more accurate than RGU/MCU in estimating stricture length (both short and intermediate) and localizing the stricture location. Use of SUG in conjunction with RGU/MCU helps in better guidance of stricture management by improving preoperative assessment. Further studies with larger sample sizes are warranted.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 262-266"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major injury of the external iliac artery during robotic nephroureterectomy: Examining the surgical management and unexpected pathology finding","authors":"Riccardo Bertolo,&nbsp;Luca Roggero,&nbsp;Claudio Brancelli,&nbsp;Giovanni Corghi,&nbsp;Filippo Migliorini,&nbsp;Alessandro Veccia,&nbsp;Luca Mezzetto,&nbsp;Gian Franco Veraldi,&nbsp;Anna Caliò,&nbsp;Matteo Brunelli,&nbsp;Guido Martignoni,&nbsp;Antonio Benito Porcaro,&nbsp;Maria Angela Cerruto,&nbsp;Alessandro Antonelli","doi":"10.1016/j.ajur.2024.04.005","DOIUrl":"10.1016/j.ajur.2024.04.005","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 275-277"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel single-port robotic system in urology: A prospective multicenter single-arm clinical trial evaluating feasibility and efficacy of first 50 cases","authors":"Zheng Wang ,&nbsp;Chao Zhang ,&nbsp;Taile Jing ,&nbsp;Yong Wei ,&nbsp;Chengwu Xiao ,&nbsp;Yang Wang ,&nbsp;Yu Fang ,&nbsp;Xiaofeng Wu ,&nbsp;Shouyan Tang ,&nbsp;Hong Xu ,&nbsp;Yi Liu ,&nbsp;Bo Yang ,&nbsp;Shuo Wang ,&nbsp;Bin Xu ,&nbsp;Qingyi Zhu ,&nbsp;Dan Xia ,&nbsp;Zhenjie Wu ,&nbsp;Xiaofeng Gao ,&nbsp;Linhui Wang","doi":"10.1016/j.ajur.2024.07.002","DOIUrl":"10.1016/j.ajur.2024.07.002","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess the feasibility and safety of the SHURUI single-port robotic surgical system for a range of major urological surgeries.</div></div><div><h3>Methods</h3><div>In this prospective, multicenter clinical trial, we examined the effectiveness of the SHURUI single-port robotic surgical system in urological interventions. The first 50 patients from four centers in China underwent single-port surgeries including partial nephrectomy, radical prostatectomy, partial adrenalectomy, and pyeloureteroplasty, exclusively by the SHURUI single-port robotic surgical system. The study's primary endpoints focused on the success of surgeries, defined as no deviations from planned procedures, no need for more than one port, and no re-operations within 24 h after surgery. Secondary endpoints encompassed a range of surgical metrics, functional outcomes, and patient demographic data. Clinical assessments were conducted before surgery, before discharge, and 1 month after discharge.</div></div><div><h3>Results</h3><div>The surgical procedures were executed successfully without requiring intraoperative conversions or transfusions. Both estimated blood loss and operation durations were maintained within satisfactory limits. For each type of surgery, the mean console times and estimated blood loss were 179.8 (standard deviation [SD] 39.4) min and 125.6 (SD 126.0) mL for radical prostatectomy, 126.7 (SD 47.8) min and 39.2 (SD 54.4) mL for partial nephrectomy, 112.6 (SD 37.4) min and 20.0 (SD 13.2) mL for partial adrenalectomy, and 148.0 (SD 18.2) min and 18.0 (SD 17.9) mL for pyeloureteroplasty, respectively. Across the cohort, 17 patients experienced a total of 25 adverse events, while 10 postoperative complications, all rated as Clavien-Dindo grade I, were encountered by eight patients. All patients had shown recovery or improvement from these events before the end of this trial.</div></div><div><h3>Conclusion</h3><div>The SHURUI single-port robotic surgical system demonstrated feasibility and safety in the performance of major urological surgeries. These initial findings highlight the system's potential, though further research and longer follow-up are required to assess long-term outcomes.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 152-161"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical applications of artificial intelligence in robotic urologic surgery","authors":"Shady Saikali,&nbsp;Runzhuo Ma,&nbsp;Vipul Patel,&nbsp;Andrew Hung","doi":"10.1016/j.ajur.2024.06.005","DOIUrl":"10.1016/j.ajur.2024.06.005","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 139-142"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for symptomatic lymphoceles in patients undergoing robot-assisted radical prostatectomy with pelvic lymph node dissection: What we learned after more than 350 cases","authors":"João P. Manzano ,&nbsp;João H.S. de Pinho ,&nbsp;Thainã O. Azambuja ,&nbsp;Davi S. Constantin ,&nbsp;Vinicius M. de Souza","doi":"10.1016/j.ajur.2024.08.002","DOIUrl":"10.1016/j.ajur.2024.08.002","url":null,"abstract":"<div><h3>Objective</h3><div>We investigated patients who underwent robot-assisted radical prostatectomy (RARP) with pelvic lymph node dissection (PLND), analyzing the prevalence and risk factors associated with symptomatic lymphoceles (SLCs).</div></div><div><h3>Methods</h3><div>We evaluated 354 consecutive patients who underwent RARP with PLND by our team between June 2016 and December 2022. After analyzing the prevalence of SLCs, patients were divided into two groups, with and without SLCs. The variables were age, body mass index (BMI), prostate-specific antigen, surgery time, blood loss, length of stay, International Society of Urological Pathology score in the pathology, and the number of lymph nodes removed. These variables were compared between these groups using the Chi-square test and Student's <em>t</em>-test, according to the type of the variable. In all analyses, a significance level of &lt;0.05 was considered.</div></div><div><h3>Results</h3><div>The prevalence of SLCs in this sample of patients undergoing RARP with PLND was 2.0% (7/354), which is slightly lower than the minimum rate reported in the literature. In our analysis, BMI (<em>p</em>=0.041), the number of lymph nodes removed (<em>p</em>=0.007), and length of hospital stay (<em>p</em>=0.007) were factors associated with the presence of SLCs.</div></div><div><h3>Conclusion</h3><div>The prevalence of SLCs in patients undergoing RARP with PLND is approximately 2.0%. Higher BMI, greater number of lymph nodes removed, and longer length of hospital stay are factors associated with the presence of SLCs.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 232-235"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing efficacy and safety of monotherapy and combination therapy with tadalafil, tamsulosin, and silodosin for distal ureteral stones: A systematic review and meta-analysis","authors":"Sholeh Ebrahimpour ,&nbsp;Mona Kargar ,&nbsp;Mohadeseh Balvardi ,&nbsp;Ozra Tabatabaei-Malazy ,&nbsp;Pardis Asadi ,&nbsp;Mehdi Mohammadi","doi":"10.1016/j.ajur.2024.05.003","DOIUrl":"10.1016/j.ajur.2024.05.003","url":null,"abstract":"<div><h3>Objective</h3><div>Medical expulsive therapy (MET) is a suitable option for facilitating stone expulsion in patients with distal ureteral stones. This meta-analysis was conducted to compare efficacy and safety of monotherapy and combination therapy with tamsulosin, silodosin, and tadalafil on stone expulsion rate (SER) and stone expulsion time (SET), as well as their comparative safety, numbers of colic pain episodes, and need for analgesics.</div></div><div><h3>Methods</h3><div>Randomized controlled trials were retrieved by searching PubMed, Scopus, and Web of Science up to November 27, 2023. Hand-searching was also conducted in Google Scholar to find additional records. Papers in English that compared the safety and efficacy of at least two of the above agents in adults with distal ureteral stones ≤10 mm were included.</div></div><div><h3>Results</h3><div>In total, 27 studies were identified (six studies through database searches and 21 through checking reference lists and hand-searching in Google Scholar). More than half of them (<em>n</em>=15, 56%) were conducted in India. The SER significantly improved with silodosin compared with tamsulosin (odds ratio [OR] 2.24, <em>p</em>&lt;0.001), whereas the difference in SET was non-significant. Tadalafil achieved a significantly higher SER compared with tamsulosin (OR 1.42, <em>p</em>=0.042) without any difference in SET. Subgroup analysis of 5- and 10-mg doses of tadalafil showed no significant difference in SER or SET. We found no significant difference in need for analgesics (mean difference [MD −53.73, <em>p</em>=0.2) or the mean number of colic episodes (MD −0.42, <em>p</em>=0.060) between tadalafil and tamsulosin. SER or SET was not significantly different between silodosin and tadalafil. Tadalafil plus tamsulosin led to a significantly higher SER (OR 1.87, <em>p</em>&lt;0.001) and SET (MD −2.99, <em>p</em>=0.002) compared with tamsulosin, without any significant difference in adverse effects.</div></div><div><h3>Conclusion</h3><div>Compared with tamsulosin, SER significantly improved with silodosin, tadalafil, and the combination of tadalafil plus tamsulosin. Meanwhile, the difference in SET was only significant between tadalafil plus tamsulosin versus tamsulosin. It appears that tadalafil and silodosin have similar efficacy in SET and SER. All medical expulsive therapies had comparable safety.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 189-203"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New surgical robotic platforms in China and their applications in urologic surgeries","authors":"Hongkai Wang,&nbsp;Dingwei Ye","doi":"10.1016/j.ajur.2025.01.001","DOIUrl":"10.1016/j.ajur.2025.01.001","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 134-138"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single bladder instillation of gemcitabine versus mitomycin C after minimally invasive radical nephroureterectomy: A propensity-score match analysis from the ROBUUST 2.0 collaborative group","authors":"Eugenio Bologna ,&nbsp;Zhenjie Wu ,&nbsp;Antonio Franco ,&nbsp;Firas Abdollah ,&nbsp;Marco Finati ,&nbsp;Giuseppe Simone ,&nbsp;Gabriele Tuderti ,&nbsp;Leslie Claire Licari ,&nbsp;Andres F. Correa ,&nbsp;Randall Lee ,&nbsp;Ottavio De Cobelli ,&nbsp;Matteo Ferro ,&nbsp;Francesco Porpiglia ,&nbsp;Daniele Amparore ,&nbsp;Enrico Checcucci ,&nbsp;Antonio Tufano ,&nbsp;Sisto Perdonà ,&nbsp;Raj Bhanvadia ,&nbsp;Vitaly Margulis ,&nbsp;Stephan Brönimann ,&nbsp;Riccardo Autorino","doi":"10.1016/j.ajur.2024.10.006","DOIUrl":"10.1016/j.ajur.2024.10.006","url":null,"abstract":"<div><h3>Objective</h3><div>Radical nephroureterectomy (RNU) is considered the standard of care for patients with high-risk upper tract urothelial carcinoma. Current literature reveals a deficit in direct comparative studies evaluating the efficacy of different chemotherapeutic agents administered in single postoperative instillation following RNU. The primary aim of this study was to compare the bladder recurrence (BR) rates between patients receiving a single instillation of mitomycin C (MMC) versus gemcitabine (Gem) after RNU.</div></div><div><h3>Methods</h3><div>The ROBUUST (ROBotic surgery for Upper tract Urothelial cancer STudy) 2.0 is an international, multicenter registry that aggregates data on patients who have undergone curative surgery for upper tract urothelial carcinoma across participating centers from January 2015 to December 2022. Data including primary baseline variables of the patients, characteristics of the tumors, surgical management, and definitive histopathological characterizations were collected and stratified based on the type of postoperative bladder instillation: MMC (the MMC group) and Gem (the Gem group). We selected variables correlated with our primary outcome to conduct a propensity-score match analysis.</div></div><div><h3>Results</h3><div>One hundred patients in the MMC group were matched 1:1 with 100 patients in the Gem group. At 36 months of follow-up, 30 patients in the MMC group and 39 patients in the Gem group experienced BR, representing recurrence rates of 30% and 39%, respectively (<em>p</em>=0.2). The Cox proportional hazards model comparing BR between the groups revealed a hazard ratio of 1.58 (95% confidence interval: 0.98–2.55) with a non-statistically significant increased risk of BR in the Gem group compared with the MMC group (<em>p</em>=0.059).</div></div><div><h3>Conclusion</h3><div>A single perioperative instillation of Gem or MMC seems to offer similar efficacy in reducing the risk of BR in patients undergoing RNU. Further research, ideally within the framework of prospective studies, is warranted to elucidate the optimal chemotherapeutic approach in this setting.</div></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 250-257"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel ejaculation-sparing surgical technique in the patient with primary bladder neck obstruction: Results of a single-arm cohort","authors":"Marco Dellabella,&nbsp;Luca Gasparri,&nbsp;Antonio Vinci,&nbsp;Massimo Maurici,&nbsp;Redi Claudini,&nbsp;Alessandro Branchi,&nbsp;Michele Pucci,&nbsp;Edoardo Agostini","doi":"10.1016/j.ajur.2024.09.004","DOIUrl":"10.1016/j.ajur.2024.09.004","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 278-280"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotics, artificial intelligence, telepresence, and telesurgery: The future of urology","authors":"Vipul Patel,&nbsp;Shady Saikali,&nbsp;Marcio Covas Moschovas","doi":"10.1016/j.ajur.2025.03.001","DOIUrl":"10.1016/j.ajur.2025.03.001","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"12 2","pages":"Pages 131-133"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}