Journal of Dual Diagnosis最新文献_第2页

Highlights for the Journal of Dual Diagnosis from 2025. 《双重诊断杂志》2025年以来的亮点。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 Epub Date: 2025-12-29 DOI: 10.1080/15504263.2025.2606021

E Sherwood Brown

引用次数: 0

The Prevalence of Cannabis Use Disorder in Individuals with Anxiety or Related Disorders: A Systematic Review. 大麻使用障碍在焦虑或相关障碍患者中的患病率：一项系统综述。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1080/15504263.2025.2606019

Ashlee R L Coles, Jenna K Perry, Brooke B Hiscock, Jonathan M Fawcett, Nick Harris, Emily J Fawcett

{"title":"The Prevalence of Cannabis Use Disorder in Individuals with Anxiety or Related Disorders: A Systematic Review.","authors":"Ashlee R L Coles, Jenna K Perry, Brooke B Hiscock, Jonathan M Fawcett, Nick Harris, Emily J Fawcett","doi":"10.1080/15504263.2025.2606019","DOIUrl":"10.1080/15504263.2025.2606019","url":null,"abstract":"Objective: The current study aimed to systematically review the prevalence of comorbid Cannabis Use Disorder (CUD) in individuals with Anxiety and Related Disorders (ARDs).Method: PubMed, PsycInfo, and Web of Science were searched electronically to identify studies comprised of participants 18+ years, diagnosed with a current ARD via clinician interview and experiencing comorbid CUD (interview or validated screener). Of the 1646 articles identified, 11 were included.Results: Across general population samples (n = 7), approximately 1 in 30 to 1 in 5 individuals with an ARD had comorbid CUD (lifetime prevalence: 3.3%-21.6%; current prevalence: 4.3%-20.0%). Among veteran samples with PTSD (n = 4), comorbid CUD was reported in approximately 1 in 25 to 1 in 3 individuals for current prevalence (4.1%-34.0%), and about 1 in 9 for lifetime prevalence (11.3%-12.5%).Conclusion: Preliminary evidence suggests that individuals with ARDs may be susceptible to developing comorbid CUD. Current comorbidity rates may be higher among veterans with PTSD compared to adults in general population samples; however, due to the limited number of eligible studies and methodological heterogeneity, further research is needed to confirm this difference. Given the recent global increase in cannabis legalization, understanding ARD-CUD comorbidity in high-risk populations is essential to inform treatment and improve outcomes.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"3-25"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Evidence of The Reliability of The Scale for The Assessment of Positive Symptoms of Cocaine Induced Psychosis (SAPS-CIP-R) in a Sample of Cocaine Users Treated at a Therapeutic Community. 在治疗社区接受治疗的可卡因使用者样本中，可卡因诱发精神病阳性症状评估量表（sap - cip - r）可靠性的新证据

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 Epub Date: 2025-12-22 DOI: 10.1080/15504263.2025.2603710

Francisco González-Saiz, Carmen Fernández Cabrera, María Calzada Velázquez-Gaztelu, Esperanza Vergara-Moragues

{"title":"New Evidence of The Reliability of The Scale for The Assessment of Positive Symptoms of Cocaine Induced Psychosis (SAPS-CIP-R) in a Sample of Cocaine Users Treated at a Therapeutic Community.","authors":"Francisco González-Saiz, Carmen Fernández Cabrera, María Calzada Velázquez-Gaztelu, Esperanza Vergara-Moragues","doi":"10.1080/15504263.2025.2603710","DOIUrl":"10.1080/15504263.2025.2603710","url":null,"abstract":"Objective: To assess the test-retest and inter-rater reliability of the Scale for the Assessment of Positive Symptoms of Cocaine Induced Psychosis (SAPS-CIP) in a sample of cocaine users treated at a therapeutic community.Methods: Cross-sectional study of a consecutive systematic sample of patients treated for cocaine-use disorder (n = 60) at a therapeutic community in Spain. Participants completed the SAPS-CIP and the Lifetime Severity for Cocaine Use Disorder scale (LSI-C).Results: Inter-rater reliability was strong, with 15 of the 17 SAPS-CIP items presenting weighted kappa values considered \"excellent\" and the remaining two items were \"good.\" Test-retest reliability was good, with 12 of the 17 items presenting weighted kappa values considered \"good,\" 3 \"excellent,\" and two \"fair.\"Conclusions: These findings support the validity and reliability of the SAPS-CIP-R as a tool to measure and assess cocaine-induced psychotic symptoms. Further research is needed to determine the reliability and validity of instruments that assess CIP.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"48-56"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Talking About Cannabis: Perspectives of First Episode Psychosis Care Participants and Parents. 谈论大麻：首发精神病护理参与者和家长的观点。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1080/15504263.2025.2606020

Alicia Lucksted, Donna Bencivengo, Arunadevi Saravana, Yasmine Boumaiz, Julie Kreyenbuhl, Russell L Margolis, Swati Nayar, Kathryn Rinehimer, Krissa Rouse, Rachel Scheinberg, Elizabeth C Thomas, Denise D Walker, Max Wolcott, Elizabeth Burris, Ladawn Myers, Christian Kelly, Alison Swigart, Crystal L Vatza, Allison S Brandt, Deepak K Sarpal, Richard W Goldberg, Robert W Buchanan, Tyler M Moore, Megan B E Jumper, Amanda Fooks, Arielle Ered, Monica E Caulkins, Melanie Bennett

{"title":"Talking About Cannabis: Perspectives of First Episode Psychosis Care Participants and Parents.","authors":"Alicia Lucksted, Donna Bencivengo, Arunadevi Saravana, Yasmine Boumaiz, Julie Kreyenbuhl, Russell L Margolis, Swati Nayar, Kathryn Rinehimer, Krissa Rouse, Rachel Scheinberg, Elizabeth C Thomas, Denise D Walker, Max Wolcott, Elizabeth Burris, Ladawn Myers, Christian Kelly, Alison Swigart, Crystal L Vatza, Allison S Brandt, Deepak K Sarpal, Richard W Goldberg, Robert W Buchanan, Tyler M Moore, Megan B E Jumper, Amanda Fooks, Arielle Ered, Monica E Caulkins, Melanie Bennett","doi":"10.1080/15504263.2025.2606020","DOIUrl":"10.1080/15504263.2025.2606020","url":null,"abstract":"Objective: Given important links between cannabis use and psychosis, we explored communications around about cannabis use with young people receiving Coordinated Specialty Care (CSC) for first episodes of psychosis and parents of such clients. Methods: In individual semi-structured interviews, clients (n = 15) and parents (n = 16) discussed experiences, concerns, and preferences talking about cannabis use, and how such conversations could be more beneficial. Analysis followed Braun and Clark's six-phase thematic analysis. Results: We discerned four themes toward optimizing communication: (1) Respect for Developing Client Autonomy, (2) \"Good Information\" about Cannabis and Its Effects, (3) Good Communication Process, and (4) Conversations Complicated by Changing Norms. Conclusions: Analysis revealed agreement between clients and parents about what makes conversations positive, but difficulties understanding each other's perspectives, and both feeling misunderstood. Interventions that build communication skills, support these difficult conversations, and provide high quality information in non-judgmental ways could support better cannabis discourse.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"37-47"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Psychiatric Comorbidity and Retention in Substance Use Disorder Treatment: Results From Multi-Site Randomized Controlled Trials of Pharmacological and Behavioral Interventions. 精神疾病合并症与物质使用障碍治疗中滞留的关系：来自药物和行为干预的多地点随机对照试验的结果。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 DOI: 10.1080/15504263.2025.2606018

Himani Byregowda, Masoumeh Amin-Esmaeili, Ryoko Susukida, Ramin Mojtabai, Rosa M Crum

{"title":"Association Between Psychiatric Comorbidity and Retention in Substance Use Disorder Treatment: Results From Multi-Site Randomized Controlled Trials of Pharmacological and Behavioral Interventions.","authors":"Himani Byregowda, Masoumeh Amin-Esmaeili, Ryoko Susukida, Ramin Mojtabai, Rosa M Crum","doi":"10.1080/15504263.2025.2606018","DOIUrl":"10.1080/15504263.2025.2606018","url":null,"abstract":"Objective: To examine the association of comorbid mood and/or anxiety disorders (M/AD) and psychological distress (PD) with treatment retention in substance use disorder (SUD) trials. Methods: Data are from 21 NIDA-sponsored randomized controlled trials (RCTs) for SUDs (n = 5,404). M/AD was assessed using the DSM-IV criteria and PD was assessed using the Addiction Severity Index. Treatment retention was defined as trial completion based on last visit attendance. Analyses used doubly-robust multivariable logistic regression with propensity score weighting. Results: Average treatment retention was 71.8%. Comorbid M/AD was associated with higher odds of treatment retention in pharmacological trials of cocaine and methamphetamine use disorder. However, comorbid PD was associated with lower treatment retention in behavioral trials of any stimulant use disorders and higher retention in pharmacological trials of methamphetamine use disorder. Conclusion: M/AD is associated with better treatment retention in SUD trials, while PD's effects depend on treatment type and trial target substance.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"67-79"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12961725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Effectiveness of Long Acting Injectable Versus Oral Naltrexone in Patients with Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder. 长效注射纳曲酮与口服纳曲酮治疗合并创伤后应激障碍和酒精使用障碍的疗效比较

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2026-01-01 Epub Date: 2025-12-20 DOI: 10.1080/15504263.2025.2603711

Luke R Rozema, Eleanor J Murray, Bradley V Watts, Jiang Gui, Jaimie L Gradus, Brian R Shiner

{"title":"Comparative Effectiveness of Long Acting Injectable Versus Oral Naltrexone in Patients with Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder.","authors":"Luke R Rozema, Eleanor J Murray, Bradley V Watts, Jiang Gui, Jaimie L Gradus, Brian R Shiner","doi":"10.1080/15504263.2025.2603711","DOIUrl":"10.1080/15504263.2025.2603711","url":null,"abstract":"Objective: To compare the effectiveness of long-acting injectable (LAI) versus oral naltrexone in improving post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) outcomes in United States Department of Veterans Affairs (VA) patients with co-occurring PTSD and AUD.Methods: We reviewed medical records of patients with PTSD and AUD receiving VA care from 10/1/1999 and 9/30/2019. Participants met eligibility criteria for an emulated clinical trial comparing LAI and oral naltrexone (n = 3739). We used inverse probability weights to adjust for possible confounding. PTSD symptom change was assessed using the PTSD Checklist for DSM-V (PCL-5). Alcohol consumption and adverse psychiatric outcomes were also assessed in a 2-year continuity phase.Results: Under the assumption of no residual confounding, we estimated that continuous use of LAI was associated with a 11.9% decrease 95% CI [-22.3, 0.8] in the probability of having clinically meaningful improvement in PTSD symptoms compared to continuous oral naltrexone use over 12-weeks. However, we found no difference in improvement comparing initiation of LAI versus oral naltrexone (-1.8% [95% CI: -11.4, 7.4]). No differences were observed in the probability of PTSD remission, probability of AUD remission, or rates of adverse psychiatric outcomes.Conclusion: Our analyses suggest that LAI naltrexone provides no benefits in improving PTSD or AUD outcomes compared to its oral counterpart among patients with comorbid PTSD and AUD. In fact, our results suggest that oral naltrexone may provide an increased probability of clinically meaning PTSD improvements if a high level of medication adherence is maintained.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"57-66"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145795163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meaningful Employment Among Veterans with Co-Occurring Substance Use and Mental Health Disorders. 同时存在物质使用和精神健康障碍的退伍军人的有意义就业

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2025-07-01 Epub Date: 2025-06-16 DOI: 10.1080/15504263.2025.2517179

Brian J Stevenson, Amanda Falcón, Erin Reilly, Steven D Shirk, Taylor Hunt, Lisa Mueller

{"title":"Meaningful Employment Among Veterans with Co-Occurring Substance Use and Mental Health Disorders.","authors":"Brian J Stevenson, Amanda Falcón, Erin Reilly, Steven D Shirk, Taylor Hunt, Lisa Mueller","doi":"10.1080/15504263.2025.2517179","DOIUrl":"10.1080/15504263.2025.2517179","url":null,"abstract":"Objective: To examine associations between employment-based self-regulatory processes and meaningful employment attainment among veterans with co-occurring conditions. Methods: A survey was administered to a national Qualtrics panel of 534 employed veterans self-reporting mental health and substance use conditions. We tested whether career exploration, goal clarity, job-searching skills, and self-regulation skills explained unique variance in meaningful employment beyond other relevant predictors: mental health symptoms, alcohol and drug use severity, economic constraints, marginalization, job prestige, and employment status. Results: Hierarchical regression analysis revealed career exploration, goal clarity, job-searching skills, and self-regulation skills were significantly associated with meaningful employment beyond other predictors. Job prestige, employment status, and mental health symptoms also had significant associations with meaningful employment, while economic constraints and alcohol use lost significance in the final model. Conclusions: Interventions promoting exploration, goal clarity, job-searching, and self-regulation may improve meaningful employment attainment while buffering the effects of alcohol use and economic constraints.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"212-223"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Meta-Analysis on the Effect of Depression on Adherence to Medication for Opioid Use Disorder. 抑郁症对阿片类药物使用障碍药物依从性影响的meta分析。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2025-07-01 Epub Date: 2025-06-18 DOI: 10.1080/15504263.2025.2515018

Taylor R Fox, Anna C S Garrison, Kyle S Minor, Jesse C Stewart, Melissa A Cyders

{"title":"A Meta-Analysis on the Effect of Depression on Adherence to Medication for Opioid Use Disorder.","authors":"Taylor R Fox, Anna C S Garrison, Kyle S Minor, Jesse C Stewart, Melissa A Cyders","doi":"10.1080/15504263.2025.2515018","DOIUrl":"10.1080/15504263.2025.2515018","url":null,"abstract":"Objective: U.S. Food and Drug Administration (FDA)-approved medications for Opioid Use Disorder (MOUD) effectively reduce opioid cravings, use, relapse, and overdose. However, adherence to MOUD is a significant challenge. Depression relates to poorer adherence across several medical conditions and may be a prime factor relating to poor MOUD adherence. The goal of this meta-analysis is to quantify the relationship between depression and MOUD adherence and to identify moderators of this association. Methods: A systematic literature search was conducted using PsycINFO, PubMed, Embase, and Cumulative Index of Nursing and Allied Health Literature [CINAHL] databases. Pearson's r was used for the effect size statistic. A random effects model was utilized for all effect size analyses. Results: Nine studies met eligibility criteria, with a total of 3493 participants. Higher baseline depressive symptoms were found to predict greater prospective adherence to MOUD (r = 0.130, 95% CI: 0.060-0.199, p < .001). This effect was not moderated by the MOUD type or depression measurement type. Conclusions: In contrast to prior medical adherence research, depression predicted better, not poorer, adherence to MOUD. The literature was limited by few studies examining naltrexone, limited diversity of samples, and a lack of clear consensus on adherence measurement. Future research should test whether this relationship extends to naltrexone; use samples with more racial minorities, women and gender minorities, and inpatient samples; clearly define and measure adherence, and identify mechanisms and moderators of this relationship, to best inform future clinical applications and improve outcomes for those with OUD.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"237-250"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent Disorders and Treatment Outcomes: A Meta-Analysis. 并发疾病和治疗结果：荟萃分析。

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2025-07-01 Epub Date: 2025-09-04 DOI: 10.1080/15504263.2025.2515015

Kathryn Danielle Scott, Kevin Michael Gorey

{"title":"Concurrent Disorders and Treatment Outcomes: A Meta-Analysis.","authors":"Kathryn Danielle Scott, Kevin Michael Gorey","doi":"10.1080/15504263.2025.2515015","DOIUrl":"10.1080/15504263.2025.2515015","url":null,"abstract":"Objectives: This rapid review and meta-analysis explores two hypotheses. First, people with a concurrent mental health and substance use disorder (SUD) respond less favorably to currently utilized treatment interventions, than do those with a single disorder. Second, the potential for certain already vulnerable groups including women, members of racialized minority groups and those who live in or near poverty may be even further disadvantaged.Methods: A multimethod sampling frame of 35 previous systematic reviews and or meta-analyses (2000-2024) augmented with peer-reviewed and grey research literature databases (2020-2024), resulted in the selection of 13 primary studies.Results: The pooled, sample-weighted risk ratio of 1.71 (95% confidence interval 1.38, 2.13) seemed to strongly suggest that those with concurrent disorders are largely disadvantaged in treatment compared to those with a single disorder.Conclusions: The results of this review confirmed people with a concurrent disorder are twice as likely to experience such undesirable outcomes as relapse and related poor outcomes including emergency department visits, rehospitalization and death. However, no evidence was found enabling exploration of potential moderations of overall treatment effects by gender, race or income.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"251-265"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bipolar Disorder Hospitalizations and Substance Use Disorders: A Nationwide Retrospective Study From 2008 To 2015. 双相情感障碍住院和物质使用障碍：2008 - 2015年全国回顾性研究

IF 2.6 4区医学

Journal of Dual Diagnosis Pub Date : 2025-07-01 Epub Date: 2025-06-17 DOI: 10.1080/15504263.2025.2515027

Leonor Valente, Alberto Freitas, Manuel Gonçalves-Pinho

{"title":"Bipolar Disorder Hospitalizations and Substance Use Disorders: A Nationwide Retrospective Study From 2008 To 2015.","authors":"Leonor Valente, Alberto Freitas, Manuel Gonçalves-Pinho","doi":"10.1080/15504263.2025.2515027","DOIUrl":"10.1080/15504263.2025.2515027","url":null,"abstract":"Objective: Bipolar Disorder (BD) is often complicated by co-occurring substance use disorders (SUD). We assessed the prevalence of SUD among BD hospitalization episodes and analyzed its association with hospitalization outcomes.Methods: We performed a retrospective observational study using a database containing all hospitalizations registered in Portuguese public hospitals from 2008 to 2015. Hospitalizations with a primary or secondary diagnosis of BD were selected. To compare episodes with and without a diagnosis of SUD, an independent sample t-test was used for age, whereas the non-parametric Mann-Whitney U test was used for LoS, CCI, and charges. Sex, in-hospital mortality, re-hospitalizations, and psychiatric comorbidities were analyzed using the Pearson's chi-squared test.Results: SUD was registered in 11.3% of episodes, with alcohol use disorder being the most prevalent (5.8%). A non-linear increase in the number of hospitalizations throughout the study period was found. Episodes with a concomitant register of SUD were associated with younger (44.1 ± 12.5 years old) and male hospitalizations (56.6%), shorter length of stay (LoS) (15.0 (8.0;24.0) days), higher Charlson Comorbidity Index (CCI) (0.24 ± 0.76), and with higher rates of attention-deficit, conduct, and disruptive behavior disorders, personality disorders, and suicide and intentional self-inflicted injury, compared to those without this comorbidity.Conclusions: Comorbid SUD increased and had a measurable impact on BD hospitalization outcomes. Timely detection and management of SUD among BD patients may likely prevent the high burden.","PeriodicalId":46571,"journal":{"name":"Journal of Dual Diagnosis","volume":" ","pages":"191-203"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0