European Journal of Translational Myology最新文献

{"title":"State of art of mobility medicine: some more abstracts and evidence that the success of Pdm3 is based on extra-session relationships.","authors":"Ugo Carraro, Marie Sophie Alberty, Stephen Anton, Elena Barbieri, Ines Bersch, Gerardo Bosco, Daniele Coraci, Paolo Gargiulo, Paulo Gentil, Ashraf S Gorgey, Maria Chiara Maccarone, Winfried Mayr, Giuseppe Messina, Philippe Perrin, Tiziana Pietrangelo, Marco Quadrelli, Piero Sestili, Daniela Tavian, Lucrezia Tognolo, Stefano Masiero, Riccardo Forni","doi":"10.4081/ejtm.2024.12492","DOIUrl":"10.4081/ejtm.2024.12492","url":null,"abstract":"<p><p>Scientific conferences increasingly suffer from the need for short presentations in which speakers like to dwell on the details of their work. A mitigating factor is to encourage discussion and planning of collaborations by organizing small meetings in a hotel large enough to host all attendees. This extends discussions' opportunities during morning breakfasts, lunches, dinners and long evenings together. Even if the vast majority of participants will not stay for the entire duration of the Conference, the possibilities for specialists to interact with specialists who are even very distant in terms of knowledge increase enormously. In any case, the results in terms of new job opportunities for young participants outweigh the costs for the organizers. Thirty years of Padova Muscle Days offer many examples, but the authors of this report on the state of the art of Mobility Medicine testify that this also happened in the 2024 Five Days of Muscle and Mobility Medicine (2024Pdm3) hosted at the Hotel Petrarca, Thermae of Euganea Hills and Padua, Italy which is in fact a valid countermeasure to the inevitable tendencies towards hyperspecialization that the explosive increase in scientific progress brings with it.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An updated view of the structural basis for dihydropyridine receptors-ryanodine receptors direct molecular interaction in skeletal muscle.","authors":"Clara Franzini-Armstrong","doi":"10.4081/ejtm.2024.12476","DOIUrl":"10.4081/ejtm.2024.12476","url":null,"abstract":"<p><p>This presentation reviews images of electron micrographs from various skeletal muscles identifying a consistent association of diydropyridine receptors (DHPR) tetrads with  alternate ryanodine receptors. Imaging of the junctional gap in triads from various sources  provide direct evidence for the  association of four diydropyridine receptors (DHPRs), clustered into tetrads, with alternate ryanodine receptors (RyRs). It is not clear whether firing of all four components of a tetrad is necessary to fully activate the opening of the RyR channel.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of brain tissue oxygen saturation in neonatal respiratory distress syndrome: a clinical study.","authors":"Keping Cheng, Huijie Zhu, Zikai Zhou, Weiyuan Chen, Aijuan Yang","doi":"10.4081/ejtm.2024.11863","DOIUrl":"10.4081/ejtm.2024.11863","url":null,"abstract":"<p><p>Neonatal respiratory distress syndrome (NRDS) is one of the major causes of pre-term mortality and morbidity among very-low-birth-weight infants (VLBWI) in low- and middle-income countries (LMIC). Some of the neonates pass away despite admission and care in intensive care units (ICUs). The present clinical trial seeks the application value of elevating oxygen saturation in the brain cells of pre-term neonates born with NRDS. Near-infrared spectroscopy (NIRS) was used to monitor the neonates' microscopic cerebral oxygenation levels do determine hemoglobin concentration in brain tissues, whereas the pulse oximetry was used to measure oxygenation levels among the patients. In statistical analyses, the Analysis of Variance (ANOVA), and descriptive statistics was deployed in the Jupyter Notebook environment using Python language. High saturation of oxygen in the brain tissues result in important biological and physiological processes, including enhanced oxygen supply to cells, reduced severity of NRDS, and balancing oxygen demand and supply. The correlations of oxygen saturation with systemic saturation of oxygen, the saturation of oxygen in brain tissues, the association between brain-specific and systemic saturation, and the impact of these outcomes on clinical practices were deliberated. Also, the pH gas values, the saturation of oxygen in neonates' brain tissues, metabolic acidosis, the effect of acid-base balance and cerebral oxygen supply, and the oxygenation of brain tissues and the pH values emerged as important variables of oxygenation of brain tissues in pre-term neonates. Oxygen saturation in brain cells influence vital physiological and biological processes. Balancing acid-base saturation or levels is needed despite the challenging achievement. Oxygenation of brain tissues improve the brain's overall functioning.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress distribution pattern in all-on-four maxillary restorations supported by porous tantalum and solid titanium implants using three-dimensional finite element analysis.","authors":"Faeze Masoomi, Farhang Mahboub","doi":"10.4081/ejtm.2024.12170","DOIUrl":"10.4081/ejtm.2024.12170","url":null,"abstract":"<p><p>Success/failure of dental implants depends on stress transfer and distribution at the bone-implant interface. This study aimed to assess the stress distribution pattern in all-on-four maxillary restorations supported by porous tantalum and solid titanium implants using three-dimensional (3D) finite element analysis (FEA). In this FEA, a geometric model of an edentulous maxilla, Zimmer screw-vent tantalum and solid titanium implants were modelled. Four models with the all-on-four concept were designed. The fifth model had 6 vertical implants (all-on-six). Two different implant types (porous tantalum and solid titanium) were modelled to yield a total of 10 models, and subjected to 200 N bilateral vertical load. Pattern of stress distribution and maximum von Mises stress values in cancellous and cortical bones around implants were analysed. In tantalum models, the effect of increasing the distal tilting of posterior implants was comparable to the effect of increasing the number of implants to 6 on von Mises stress values in cortical bone. However, in cancellous bone, the effect of increasing the tilting of posterior implants on stress was slightly greater than the effect of increasing the number of implants to 6. In solid titanium models, the effect of both of the abovementioned parameters was comparable on stress in cancellous bone; but in cortical bone, the effect of increasing the implant number was slightly greater on stress reduction. Despite similar pattern of stress distribution in bone around implants, higher maximum von Mises stress values around tantalum implants indicate higher stress transfer capacity of this type of implant to the adjacent bone, compared with solid titanium implants.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of the ubiquitin-proteasome system in the sarcopenic-like phenotype induced by CCL5/RANTES.","authors":"Sabrina Conejeros-Lillo, Francisco Aguirre, Daniel Cabrera, Felipe Simon, Luis Peñailillo, Claudio Cabello-Verrugio","doi":"10.4081/ejtm.2024.12249","DOIUrl":"10.4081/ejtm.2024.12249","url":null,"abstract":"<p><p>Sarcopenia is characterized by reduced muscle strength and mass and a decline in muscle fiber diameter and amount of sarcomeric proteins. Sarcopenia involves the activation of the ubiquitin-proteasome system (UPS). MuRF-1 and atrogin-1 are E3 ubiquitin ligases belonging to UPS, leading to proteolysis mediated by the PSMB 5, 6, and 7 subunits of 20S proteasome. CCL5/RANTES induces a sarcopenic-like effect in muscle cells. The present work explored the impact of CCL5 on UPS components and the influence of UPS on its sarcopenic-like effect. We demonstrated that CCL5 increased MuRF-1 and atrogin-1 protein levels and mRNA levels of subunits PSMB 5, 6, and 7. We used the MG132 inhibitor to elucidate the role of the 20S proteasome in the CCL5-induced sarcopenic-like effect. This inhibitor prevented the decrease in troponin and MHC protein levels and partially prevented the reduction in the diameter of single-isolated FDB muscle fibers induced by CCL5. These findings indicate that CCL5 actively modulates the UPS. Moreover, our results show the direct participation of UPS in the sarcopenic-like phenotype induced by CCL5.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masticatory performance and oral health related to quality of life before and after orthodontic treatment: a systematic review and meta-analysis.","authors":"Berahman Sabzevari, Arezousadat Fatemi, Milad Soleimani, Seyed Masoud Sajedi, Roksana Babazadehkhoushrodi","doi":"10.4081/ejtm.2024.12101","DOIUrl":"10.4081/ejtm.2024.12101","url":null,"abstract":"<p><p>Masticatory performance is considered an important step in the beginning of the digestive process and considering the patient's aesthetic and functional factors, it is necessary to choose appropriate treatments. Based on the evidence during orthodontic treatment, the restoration of the physiological function of masticatory performance should not be neglected. The present study aimed to evaluate the association between orthodontic treatment and improved masticatory performance and oral health related to quality of life. In the present study, all articles published till the end of August 2023 were extracted by two trained researchers independently through a search in databases like PubMed, Scopus, Science Direct, ISI, Web of Knowledge, Elsevier, Wiley, and Embase, and Google Scholar search engine using keywords and their combinations. Data analysis was done using the fixed effects model in a meta-analysis, by STATA (version 17); a P-value of less than 0.05 was considered significant. Based on the results, the mean difference in masticatory performance between pre-treatment and post-treatment was 2.23 (MD: 2.23; 95CI, 2.17, 2.29. p<0.01; I2= 99.98%; p<0.01). The mean difference in oral health related to quality of life between pre-treatment and post-treatment was -32.23 (MD: -32.23; 95CI, -33.35, -31.11. p<0.01; I2= 97%; p<0.01). Orthodontic treatment had a positive effect on masticatory performance and improved the quality of life of patients after treatment.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The healing effect of the all inside technique is superior to the traditional technique in the reconstruction of the anterior cruciate ligament.","authors":"Xiong Li, Wu Cao, Hongyu Zhou, Ruida Ji, Jian Xiao, Chen Zhao","doi":"10.4081/ejtm.2024.11970","DOIUrl":"10.4081/ejtm.2024.11970","url":null,"abstract":"<p><p>Our main objective was to examine the curative effect of all inside technique and traditional technique in anterior cruciate ligament (ACL) reconstruction. In our retrospective study at the First People's Hospital of Jiashan County, we analyzed 88 participants with ACL injuries (50 males, 38 females, average age 27 years). They were randomly divided into two groups: traditional ACL reconstruction (42 participants) and all inside ACL reconstruction (46 participants). We measured and recorded the Visual Analog Scores (VAS), International Knee Documentation Committee (IKDC), Lysholm scores, operation time, graft diameter and length between the traditional technique group and all inside technique group. There were statistically significant differences in the Lysholm scores and IKDC scores between traditional and all inside technique groups. The all inside technique showed a higher efficacy and effective post-operative recovery with minimal pain and recurrent injuries. Our findings showed that the differences in gender, age, side of injury and operation time were not significant (p> 0.05). Follow-up was conducted at 6 months and 12 months post operations (mean, 7.5 ± 1.1 months). All inside technique minimizing tissue disruption, optimizing graft placement and facilitating early recovery have a significant impact on patient outcomes.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disorders and other medical and socio-demographic factors in systemic scleroderma.","authors":"Leyla Bagheri, Hoda Kavosi, Nasim Shokouhi, Shila Aghayani, Khosro Sadeghniiat Haghighi, Seyed Reza Najafizadeh","doi":"10.4081/ejtm.2024.12183","DOIUrl":"10.4081/ejtm.2024.12183","url":null,"abstract":"<p><p>We aimed to investigate sleep disorders in patients with systemic scleroderma (SSc) and its relationship with socio-demographic and medical factors and to provide a suitable solution to better control the disease and improve the quality of life in these patients. This cross-sectional study evaluated SSc patients seen at a rheumatology clinic from September 1, 2022, through April 1, 2023.The patients were examined by the main investigator of the project and entered the study after taking the medical history and meeting the criteria of ACR 2013 Classification Criteria. Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS) and STOP-Bang Questionnaire were employed to investigate sleep disorders. A total of 103 patients were included in the study. The average age of the patients was 48.42 ± 12.4 years. PSQI showed lower quality of sleep scores among SSc (68% of patients), which was significantly related to the degree of skin stiffness in patients, telangiectasia, interstitial lung disease (ILD) in computed tomography (CT) scan, patient age, duration of the disease, and pulmonary artery pressure (PAP). STOP-Bang Questionnaire revealed that obstructive sleep apnea (OSA) was significantly associated with telangiectasia, ILD, patient age, disease onset age, disease duration, body mass index and PAP. Insomnia had a statistically significant relationship with telangiectasia, ILD and patient age. Drowsiness during daily activities was not significantly related to any of the individual variables and disease-related variables. Sleep disorders are common in patients with systemic scleroderma. Telangiectasia, ILD and patient age were related to all sleep quality disorders and respiratory apnea and insomnia. Furthermore, the amount of skin involvement significantly causes disturbances in the quality of sleep of patients, where in the group with diffuse skin stiffness, 80% of patients exhibited disturbances in the quality of sleep. Therefore, paying attention to sleep health can be an effective factor in improving the quality of life of patients with SSc.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of retrospective and prospective memory in subtypes of obsessive-compulsive disorder.","authors":"Mohammadtaghi Yazarloo, Mehdi Reza Sarafraz, Saeide Jabbari, Taraneh Gholipour, Touraj Hashemi","doi":"10.4081/ejtm.2024.12221","DOIUrl":"10.4081/ejtm.2024.12221","url":null,"abstract":"<p><p>Retrospective and prospective memory deficits play a role in maintaining and perpetuating the symptoms of obsessive-compulsive disorder (OCD), but less is known about these deficits in different subtypes of OCD. The aim of the present study was to evaluate the retrospective and prospective memory in patients suffering from cleaning, checking, symmetry, and religious obsessions. In a comparative causal method, 60 participants aged 28 to 55, in 2023, were selected by convenience sampling and placed in five groups of individuals with cleaning, checking, symmetry, religious obsessions, and a healthy group. Participants completed self-report questionnaires and neurocognitive tools. Results showed that defects in retrospective memory were significant in all types of obsessions (p<0.05) except religious obsessions. Also, this defect was more severe in checking obsession disorder compared to other types of OCD. Also, the finding indicated that the defect in prospective memory was significant only in checking obsession disorder (p<0.05). Retrospective and prospective memory impairments and their relationship with deficits in executive functions can be different depending on the type of OCD. Based on the findings, impairment of executive function indirectly by impacting the impairment of other cognitive mechanisms diminishes confidence in retrospective and prospective memory which leads to compulsive behaviors in individuals with contamination and checking obsessions. Also, the impairment of retrospective memory in symmetry obsessions might have a relationship with information encoding, which in turn leads to difficulty recalling information from memory.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in anthropometric and somatotype profiles of Brazilian female futsal players: a 20 year study.","authors":"Vinicius Muller Reis Weber, Diego Bessa Dantas, Danilo Fernandes da Silva, Timothy Gustavo Cavazzotto, Bruno Sergio Portela, Sandra Aires Ferreira, Marcos Roberto Queiroga","doi":"10.4081/ejtm.2024.11887","DOIUrl":"10.4081/ejtm.2024.11887","url":null,"abstract":"<p><p>This study describes the anthropometric measurements and somatotype of the elite female futsal players from Brazil in 2021 and analyse the changes and trends over time in these physical characteristics. Data were collected from the 396 female futsal players, of whom; 169 players were assessed in 2021 then compared to those assessed in 2001 (n=112) and 2011 (n-115). Anthropometric measurements, including body weight, height, breadths, girths, and skinfolds were assessed. The somatotype was calculated and graphically represented. The changes between 2021 and the previous years were analysed using ANOVA and multiple linear regression. A jointpoint regression was performed to verify the annual percentage change. The comparison between 2021 data versus the other time points showed a higher age and lower fat content (2001: 22.7 ± 5.1 BF%; 2011: 22.2 ± 5.2 BF%; 2021: 19.0 ± 5.1 BF%). Players from 2021 had higher tensed arm and relaxed calf girths. All the positions, excluding pivots, significantly decreased their body fat units between 2021 and 2001 (goalkeeper: b=-4.49; defender: b=-2.78; winger: b=-4.48). Over the last 20 years, body fat reduced, and tensed arm and relaxed calf girths increased, suggesting an increase in fat-free mass content from the limbs.</p>","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}