European Journal of Translational Myology最新文献_第10页

Efficacy and safety of postoperative levothyroxine sodium tablets for improving serum thyroid hormone levels and tumor marker levels in patients with thyroid tumors. 左甲状腺素钠片改善甲状腺肿瘤患者血清甲状腺激素水平和肿瘤标志物水平的疗效和安全性。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-09-05 DOI: 10.4081/ejtm.2023.11582

Dingji Hao, Linxiao Tian, Haoting He, Congru Zhu, Lili Guo, Keao Zhang, Jie Zhang

{"title":"Efficacy and safety of postoperative levothyroxine sodium tablets for improving serum thyroid hormone levels and tumor marker levels in patients with thyroid tumors.","authors":"Dingji Hao, Linxiao Tian, Haoting He, Congru Zhu, Lili Guo, Keao Zhang, Jie Zhang","doi":"10.4081/ejtm.2023.11582","DOIUrl":"10.4081/ejtm.2023.11582","url":null,"abstract":"Levothyroxine tablet has been used for improving serum thyroid hormones. Despite its efficacy, there has been a persistent recurrence. We aimed to evaluate the efficacy of levothyroxine regimen (administered as sodium tablets or liquid) therapy, including the regime in combination with other thyroxine hormones, to determine its effectiveness and safety regarding thyroid tumor patient outcomes. An electronic search of the online databases (PubMed, EMBASE, and Web of Science) was performed in duplicate independently by two authors (SSK and LPY) to identify any potential studies published in the English language from January 2002 to October 2022. The records were retrieved using keywords and MeSH terms. The Cochrane risk of bias tool in the Review Manager (RevMan software version 5.4.) was used to evaluate the risk of bias in the included studies. A total of 18 quality studies were reported on levothyroxine tablets. Results showed that liquid levothyroxine was more efficient than tablet levothyroxine. Further results showed that levothyroxine in combination with L-T3 or I-131 was more effective than L-T4 tablet monotherapy for improving thyroid cancer hormones. Levothyroxine tablet monotherapy is less efficient than liquid levothyroxine and/or levothyroxine combined therapy. This research recommends future research using larger randomized controlled studies.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/17/f2/ejtm-33-3-11582.PMC10583153.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10508288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of physical activity on long COVID fatigue: an unsolved enigma. 体育活动对长期新冠肺炎疲劳的影响：一个尚未解决的谜。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-09-04 DOI: 10.4081/ejtm.2023.11639

Francesco Coscia, Ester Sara Di Filippo, Paola Virginia Gigliotti, Giorgio Fano Illic

{"title":"Effect of physical activity on long COVID fatigue: an unsolved enigma.","authors":"Francesco Coscia, Ester Sara Di Filippo, Paola Virginia Gigliotti, Giorgio Fano Illic","doi":"10.4081/ejtm.2023.11639","DOIUrl":"10.4081/ejtm.2023.11639","url":null,"abstract":"Covid-19 disease is well documented and often the most common symptoms include myalgia and muscle fatigue. Approximately 10% of those infected complain of persistent fatigue even many months after the end of the acute phase of the disease. This gives rise to a condition different from the previous one and commonly known as 'post-acute COVID-19 syndrome' or simply Long-COVID. Although the origin of muscle fatigue is multifactorial, the state of prolonged fatigue observed in the Long-COVID syndrome suggests the existence of a possible state of atrophy or rather acute sarcopenia. Under these conditions, the use of physical activity programs can effectively counteract the state of atrophy underlying the fatigue phenomena observed. If this is also the situation during the Long-COVID, the muscular symptom should be positively influenced by the administration of programmed physical activity cycles. In fact, in patients with Long-COVID, the few published papers seem to indicate that patients who are physically active and who make an effort to engage in physical activity even during the illness have decreased duration and intensity of the illness. However, analysis of the studies in the literature also suggests that a small percentage of people with Long-COVID do not appear to benefit from the application of physical activity programs, so further studies on homogeneous samples are needed to provide a firm answer to the question: can planned physical activity help patients during the pathological course of Long-COVID?","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a6/56/ejtm-33-3-11639.PMC10583148.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10145538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conventional physical therapy combined with extracorporeal shock wave leads to positive effects on spasticity in stroke survivors: a prospective observational study. 常规物理治疗结合体外冲击波对中风幸存者的痉挛有积极影响：一项前瞻性观察研究。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-09-04 DOI: 10.4081/ejtm.2023.11607

Emanuela Elena Mihai, Jannis Papathanasiou, Kiril Panayotov, Yana Kashilska, Eugenia Rosulescu, Calogero Foti, Mihai Berteanu

{"title":"Conventional physical therapy combined with extracorporeal shock wave leads to positive effects on spasticity in stroke survivors: a prospective observational study.","authors":"Emanuela Elena Mihai, Jannis Papathanasiou, Kiril Panayotov, Yana Kashilska, Eugenia Rosulescu, Calogero Foti, Mihai Berteanu","doi":"10.4081/ejtm.2023.11607","DOIUrl":"10.4081/ejtm.2023.11607","url":null,"abstract":"The study aimed to evaluate the effectiveness of radial extracorporeal shock wave therapy (rESWT) and conventional physical therapy (CPT) protocol on the gait pattern in stroke survivors through a new gait analysis technology. Fifteen (n=15) stroke survivors took part in this prospective, observational study and were assessed clinically and through an instrumented treadmill before and after rESWT and CPT. Spasticity grade 95% CI 0.93 (0.79 +/- 1.08), pain intensity 95% CI 1.60 (1.19 +/- 2.01), and clonus score decreased significantly 95% CI 1.13 (0.72 +/- 1.54). The sensorimotor function 95% CI -2.53 (-3.42 +/- 1.65), balance 95% CI -5.67 (-6.64 +/- - 4.69), and gait parameters were enhanced at the end of the program. Step length 95% CI -3.47 (-6.48 +/- 0.46) and step cycle were improved 95% CI -0.09 (-0.17 +/- -0.01), and hip 95% CI -3.90 (-6.92 +/- -0.88), knee 95% CI -2.08 (-3.84 +/- -0.32) and ankle flexion-extension 95% CI -2.08 (-6.64 +/- -4.69) were augmented. Adding the quantitative analysis to the clinical assessment, we gained easy access to track progress and obtained an individualized therapeutic approach for stroke survivors.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2b/c2/ejtm-33-3-11607.PMC10583146.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10152025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of body composition on cardio-respiratory fitness in futsal competitive athletes. 身体成分对五人制竞技运动员心肺功能的影响。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-09-04 DOI: 10.4081/ejtm.2023.11479

Klara Komici, Sofia Verderosa, Fabio D'Amico, Albino Parente, Ludovico Persichini, Germano Guerra

{"title":"The role of body composition on cardio-respiratory fitness in futsal competitive athletes.","authors":"Klara Komici, Sofia Verderosa, Fabio D'Amico, Albino Parente, Ludovico Persichini, Germano Guerra","doi":"10.4081/ejtm.2023.11479","DOIUrl":"10.4081/ejtm.2023.11479","url":null,"abstract":"Futsal is an intermittent high intensity sport which has become popular worldwide. Body composition and physical fitness have been studied in different sports disciplines. However, little is known regarding body composition and cardio-respiratory performance in competitive futsal players. Body composition parameters were analyzed by electrical impedance body composition analyzer in 31 competitive male futsal players. All participants performed spirometry, handgrip strength and cardiopulmonary exercise testing. Significant correlations were observed between muscle mass and spirometry parameters and peak VO2 (p≤0.05). Fat mass resulted inversely correlated with peak VO2% predicted and hand grip strength (p≤0.05). Regression analysis showed that muscle mass significantly predicts respiratory parameters (p<0.01) and reduced fat mass is associated with increased peak VO2 % predicted and handgrip strength (p<0.01). In futsal competitive athletes increased muscle mass is associated with higher spirometry parameters and fat mass is inversely associated with lower cardiorespiratory fitness.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/e6/ejtm-33-3-11479.PMC10583136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10153954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Experimental study on stabilometric complex for terrainkur in overweight people. 超重人群土鳖稳定性复合体的实验研究。

IF 1.8

European Journal of Translational Myology Pub Date : 2023-08-08 DOI: 10.4081/ejtm.2023.11495

Anatoliy D Fesyun, Irina A Grishechkina, Andrey A Lobanov, Sergei V Andronov, Andrey I Popov, Michail A Eremushkin, Kirill V Terentev, Rinat R Bogdanov, Natalia P Sanina, Igor V Reverchuk

{"title":"Experimental study on stabilometric complex for terrainkur in overweight people.","authors":"Anatoliy D Fesyun, Irina A Grishechkina, Andrey A Lobanov, Sergei V Andronov, Andrey I Popov, Michail A Eremushkin, Kirill V Terentev, Rinat R Bogdanov, Natalia P Sanina, Igor V Reverchuk","doi":"10.4081/ejtm.2023.11495","DOIUrl":"10.4081/ejtm.2023.11495","url":null,"abstract":"Overweight and obesity is a multifactorial, multisystem disease declared a global epidemic by the World Health Organization (WHO) as early as in 1997. At least 30% of the working-age population in Russia is overweight. Only the use of physical activity as an integral (basic) part of obesity treatment and maintenance of the body weight achieved in the course of treatment can achieve durable and long-lasting treatment results as well as significant changes in the body structure (fat/non-fat body weight ratio). Terrainkur (therapeutic walking) is a method of spa treatment that combines climatotherapy and physical therapy. One of the problems in physical activity in obese people is the difficulty they experience in exercising due to the impaired walking pattern caused by imbalances in the muscle chains, including pelvic region, cervical region, which reduces endurance and commitment to physical activity. The study found that the exposure group (Terrainkur) showed lower values of \"total fat\", \"metabolic age\", \"basic caloric value\" compared to initial results and the control group; the exposure group (Terrainkur) showed a decrease in the deviation of the centre of body axis projection from the proper axis, the percentage of non-compliance with the proper fluctuations of the foot underextension. These changes contributed to the elimination of terrainkur restrictions and, as a result, improved the patient compliance during the terrainkur exercises.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/cc/ejtm-33-3-11495.PMC10583137.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9975163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proteomic profiling of the brain from the wobbler mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein. 肌萎缩侧索硬化症摇摆小鼠模型大脑的蛋白质组学分析显示星形胶质细胞增生标志物神经胶质原纤维酸性蛋白水平升高。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-08-08 DOI: 10.4081/ejtm.2023.11555

Sandra Murphy, Thomas Schmitt-John, Paul Dowling, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck

{"title":"Proteomic profiling of the brain from the wobbler mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein.","authors":"Sandra Murphy, Thomas Schmitt-John, Paul Dowling, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck","doi":"10.4081/ejtm.2023.11555","DOIUrl":"10.4081/ejtm.2023.11555","url":null,"abstract":"The wobbler mouse is a widely used model system of amyotrophic lateral sclerosis and exhibits progressive neurodegeneration and neuroinflammation in association with skeletal muscle wasting. This study has used wobbler brain preparations for the systematic and mass spectrometric determination of proteome-wide changes. The proteomic characterization of total protein extracts from wobbler specimens was carried out with the help of an Orbitrap mass spectrometer and revealed elevated levels of glia cell marker proteins, i.e., glial fibrillary acidic protein and the actin-binding protein coronin. In contrast, the abundance of the actin-binding protein neurabin and the scaffolding protein named piccolo of the presynaptic cytomatrix were shown to be reduced. The increased abundance of glial fibrillary acidic protein, which is frequently used in neuropathological studies as a marker protein of glial scar formation, was confirmed by immunoblotting. In analogy, the proteomic profiling of the brain from another established murine model of motor neuron disease, the SOD1mouse, also showed increased levels of this intermediate filament protein. This suggests that neurodegenerative processes are associated with astrogliosis in both the wobbler and SOD1 brain.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/9f/ejtm-33-3-11555.PMC10583141.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9975165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mass spectrometry-based proteomic characterization of the middle-aged mouse brain for animal model research of neuromuscular diseases. 用于神经肌肉疾病动物模型研究的中年小鼠大脑基于质谱的蛋白质组学特征。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-08-03 DOI: 10.4081/ejtm.2023.11553

Paul Dowling, Margit Zweyer, Hemmen Sabir, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck

{"title":"Mass spectrometry-based proteomic characterization of the middle-aged mouse brain for animal model research of neuromuscular diseases.","authors":"Paul Dowling, Margit Zweyer, Hemmen Sabir, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck","doi":"10.4081/ejtm.2023.11553","DOIUrl":"10.4081/ejtm.2023.11553","url":null,"abstract":"Neuromuscular diseases with primary muscle wasting symptoms may also display multi-systemic changes in the body and exhibit secondary pathophysiological alterations in various non-muscle tissues. In some cases, this includes proteome-wide alterations and/or adaptations in the central nervous system. Thus, in order to provide an improved bioanalytical basis for the comprehensive evaluation of animal models that are routinely used in muscle research, this report describes the mass spectrometry-based proteomic characterization of the mouse brain. Crude tissue extracts were examined by bottom-up proteomics and detected 4558 distinct protein species. The detailed analysis of the brain proteome revealed the presence of abundant cellular proteoforms in the neuronal cytoskeleton, as well as various brain region enriched proteins, including markers of the cerebral cortex, cerebellum, hippocampus and the olfactory bulb. Neuroproteomic markers of specific cell types in the brain were identified in association with various types of neurons and glia cells. Markers of subcellular structures were established for the plasmalemma, nucleus, endoplasmic reticulum, mitochondria and other crucial organelles, as well as synaptic components that are involved in presynaptic vesicle docking, neurotransmitter release and synapse remodelling.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/5c/ejtm-33-3-11553.PMC10583138.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10000606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Combined effect of medical therapy and rehabilitation in Chronic Ataxic Neuropathy with anti-Disialosyl IgM Antibodies (CANDA): a case report. 抗二唾液糖基IgM抗体（CANDA）对慢性共济失调性神经病的药物治疗和康复的联合作用：一例报告。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-07-31 DOI: 10.4081/ejtm.2023.11557

Giulio Balestro, Alessandro Picelli, Luca Ortolani, Andrea Marcante

{"title":"Combined effect of medical therapy and rehabilitation in Chronic Ataxic Neuropathy with anti-Disialosyl IgM Antibodies (CANDA): a case report.","authors":"Giulio Balestro, Alessandro Picelli, Luca Ortolani, Andrea Marcante","doi":"10.4081/ejtm.2023.11557","DOIUrl":"10.4081/ejtm.2023.11557","url":null,"abstract":"Chronic Ataxic Neuropathy with anti-Disialosyl IgM Antibodies (CANDA) is a rare form of immune-mediated sensory ataxic neuropathy. We describe the case of a 45-year-old man, who was diagnosed with CANDA in October 2018. Since then, he has been treated with monthly courses of intravenous immunoglobulin administration (IV Ig) and, in October 2022, he underwent plasmapheresis, reporting a sudden worsening of clinical and motor picture. After a new IV Ig cycle admission, the patient was hospitalized to perform intensive rehabilitation, involving two individual sessions per day (90 minutes each) for 5 days a week. During hospitalization it was registered a relevant improvement in the muscle strength of the lower limbs (LLs). Furthermore, progressive improvements were recorded both in patient's motor performance and in his level of autonomy in activities of daily living. These results had a positive impact on his quality of life and made it possible to reduce the frequency of IV Ig treatments. This is the first case in literature reporting the combined effect of rehabilitation treatment and medical therapy in CANDA neuropathy.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/02/ejtm-33-3-11557.PMC10583142.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9895549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A. Merosin缺陷型先天性1A型肌营养不良患者的自噬增加。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-07-28 DOI: 10.4081/ejtm.2023.11501

Mariangela Mastrapasqua, Roberta Rossi, Lucrezia De Cosmo, Annalisa Resta, Mariella Errede, Antonella Bizzoca, Stefania Zampatti, Nicoletta Resta, Emiliano Giardina, Maddalena Ruggieri, Daniela Virgintino, Tiziana Annese, Nicola Laforgia, Francesco Girolamo

{"title":"Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A.","authors":"Mariangela Mastrapasqua, Roberta Rossi, Lucrezia De Cosmo, Annalisa Resta, Mariella Errede, Antonella Bizzoca, Stefania Zampatti, Nicoletta Resta, Emiliano Giardina, Maddalena Ruggieri, Daniela Virgintino, Tiziana Annese, Nicola Laforgia, Francesco Girolamo","doi":"10.4081/ejtm.2023.11501","DOIUrl":"10.4081/ejtm.2023.11501","url":null,"abstract":"The autophagy process recycles dysfunctional cellular components and protein aggregates by sequestering them in autophagosomes directed to lysosomes for enzymatic degradation. A basal level of autophagy is essential for skeletal muscle maintenance. Increased autophagy occurs in several forms of muscular dystrophy and in the merosin-deficient congenital muscular dystrophy 1A mouse model (dy3k/dy3k) lacking the laminin-α2 chain. This pilot study aimed to compare autophagy marker expression and autophagosomes presence using light and electron microscopes and western blotting in diagnostic muscle biopsies from newborns affected by different congenital muscular myopathies and dystrophies. Morphological examination showed dystrophic muscle features, predominance of type 2A myofibers, accumulation of autophagosomes in the subsarcolemmal areas, increased number of autophagosomes overexpressing LC3b, Beclin-1 and ATG5, in the merosin-deficient newborn suggesting an increased autophagy. In Duchenne muscular dystrophy, nemaline myopathy, and spinal muscular atrophy the predominant accumulation of p62+ puncta rather suggests an autophagy impairment.","PeriodicalId":46459,"journal":{"name":"European Journal of Translational Myology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/23/ejtm-33-3-11501.PMC10583158.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9895546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Correction. Frailty: future prospectives in rehabilitation medicine. 校正虚弱：康复医学的未来展望。

IF 2.2

European Journal of Translational Myology Pub Date : 2023-07-28 DOI: 10.4081/ejtm.2023.11615

The Publisher

引用次数: 0