Journal of Microbiology & Biology Education最新文献_第9页

A cost-free CURE: using bioinformatics to identify DNA-binding factors at a specific genomic locus 一种免费的治愈方法:利用生物信息学来鉴定特定基因组位点的dna结合因子

Journal of Microbiology & Biology Education Pub Date : 2023-10-24 DOI: 10.1128/jmbe.00120-23

Casey A. Schmidt, Lauren J. Hodkinson, H. Skye Comstra, Samia Khan, Henrik Torres, Leila E. Rieder

{"title":"A cost-free CURE: using bioinformatics to identify DNA-binding factors at a specific genomic locus","authors":"Casey A. Schmidt, Lauren J. Hodkinson, H. Skye Comstra, Samia Khan, Henrik Torres, Leila E. Rieder","doi":"10.1128/jmbe.00120-23","DOIUrl":"https://doi.org/10.1128/jmbe.00120-23","url":null,"abstract":"ABSTRACT Research experiences provide diverse benefits for undergraduates. Many academic institutions have adopted course-based undergraduate research experiences (CUREs) to improve student access to research opportunities. However, potential instructors of a CURE might still face financial or practical hurdles that prevent implementation. Bioinformatics research offers an alternative that is free, safe, compatible with remote learning, and may be more accessible for students with disabilities. Here, we describe a bioinformatics CURE that leverages publicly available datasets to discover novel proteins that target an instructor-determined genomic locus of interest. We use the free, user-friendly bioinformatics platform Galaxy to map ChIP-seq datasets to a genome, which removes the computing burden from students. Both faculty and students directly benefit from this CURE, as faculty can perform candidate screens and publish CURE results. Students gain not only basic bioinformatics knowledge, but also transferable skills, including scientific communication, database navigation, and primary literature experience. The CURE is flexible and can be expanded to analyze different types of high-throughput data or to investigate different genomic loci in any species.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"67 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135273274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A simple undergraduate laboratory exercise for teaching the role of sentinel-level clinical microbiology testing in biological threat identification 一个简单的本科实验室练习，用于教授哨兵级临床微生物学测试在生物威胁识别中的作用

Journal of Microbiology & Biology Education Pub Date : 2023-10-19 DOI: 10.1128/jmbe.00106-23

Christina Cox, David S. Askew

{"title":"A simple undergraduate laboratory exercise for teaching the role of sentinel-level clinical microbiology testing in biological threat identification","authors":"Christina Cox, David S. Askew","doi":"10.1128/jmbe.00106-23","DOIUrl":"https://doi.org/10.1128/jmbe.00106-23","url":null,"abstract":"ABSTRACT Undergraduate students in the biomedical sciences are mostly unaware of how clinical microbiology laboratories handle suspected agents of bioterrorism or emerging infectious diseases. The Public Health Security Bioterrorism Preparedness and Response Act of 2002 requires the US Department of Health and Human Services (HHS) to maintain a list of microbes that pose serious biological threats to human health and safety, including Tier 1 agents with the potential for use in bioterrorism. The Laboratory Response Network (LRN), founded by the Centers for Disease Control and Prevention, the Federal Bureau of Investigation, and the Association of Public Health Laboratories, coordinates the response of sentinel, reference, and national laboratories to these biothreats. The sentinel laboratories, which comprise most hospital-based and commercial laboratories, are the first to encounter a suspicious agent. For this reason, the LRN has published a series of testing guidelines to assist the sentinel laboratories in deciding whether a microbial isolate should be considered potentially hazardous and thus sent to a reference or national laboratory for further characterization. Here, we describe a simple laboratory exercise that teaches sentinel-level testing requirements in the context of an applied setting of a potential outbreak of anthrax that would require a sentinel laboratory to recognize a potential threat, attempt to rule it out, and refer to a national laboratory for identification.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135778957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing anatomy education through cooperative learning: harnessing virtual reality for effective gross anatomy learning 通过合作学习加强解剖学教育:利用虚拟现实进行有效的大体解剖学学习

Journal of Microbiology & Biology Education Pub Date : 2023-10-18 DOI: 10.1128/jmbe.00100-23

Chao-Ying Wang, Ti Yin, Kuo-Hsing Ma, Jia-Fwu Shyu, Chia-Pi Cheng, Yu-Chiao Wang, Yun-Ling Huang, Ming-Hsien Chiang

{"title":"Enhancing anatomy education through cooperative learning: harnessing virtual reality for effective gross anatomy learning","authors":"Chao-Ying Wang, Ti Yin, Kuo-Hsing Ma, Jia-Fwu Shyu, Chia-Pi Cheng, Yu-Chiao Wang, Yun-Ling Huang, Ming-Hsien Chiang","doi":"10.1128/jmbe.00100-23","DOIUrl":"https://doi.org/10.1128/jmbe.00100-23","url":null,"abstract":"ABSTRACT The advent of virtual reality (VR) in education offers unique possibilities for facilitating cooperative learning strategies, particularly in fields demanding intricate spatial understanding, such as gross anatomy. This study investigates the impact of integrating cooperative learning strategies within a VR-based gross anatomy curriculum, focusing on enhancing students’ anatomy knowledge and skills. We analyzed the performance of two cohorts of first-year nursing students across five semesters (2016–2020), where traditional learning methods were used in the first three semesters (2016–2018), and a VR-based cooperative learning approach was adopted in the last two semesters (2019–2020). Our findings suggest that the VR-based cooperative learning group achieved significantly higher scores in their gross anatomy laboratory courses compared to their counterparts learning through traditional methods. This research provides valuable insights into how the integration of VR technology and cooperative learning strategies can not only enhance learning outcomes but also improve the VR learning experience by reducing motion sickness. It accentuates the potential of VR-based cooperative learning as an impactful educational tool in anatomy education. Future research should further explore the optimal integration of VR and cooperative learning strategies in diverse course types and their potential to enhance educational outcomes and the learning experience.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135824263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From the classroom to the farm: a lesson plan that promotes smallholder farmers’ education and training about plant pathology in the context of climate change 从教室到农场:在气候变化背景下促进小农户关于植物病理学的教育和培训的课程计划

Journal of Microbiology & Biology Education Pub Date : 2023-10-16 DOI: 10.1128/jmbe.00090-23

Nicole Colón Carrión, Sofia Machiavelli Girón

引用次数: 0

Responsible and ethical conduct of research (RECR) diagnostic survey using case scenarios from biology course-based undergraduate research experiences (CUREs) 负责任和道德的研究行为(RECR)诊断调查，使用基于生物学课程的本科生研究经历(CUREs)的案例场景

Journal of Microbiology & Biology Education Pub Date : 2023-10-13 DOI: 10.1128/jmbe.00119-23

Elizabeth G. Monthofer, Jewel M. Ito, Samantha Battaglia, Laura A. Diaz-Martinez

{"title":"Responsible and ethical conduct of research (RECR) diagnostic survey using case scenarios from biology course-based undergraduate research experiences (CUREs)","authors":"Elizabeth G. Monthofer, Jewel M. Ito, Samantha Battaglia, Laura A. Diaz-Martinez","doi":"10.1128/jmbe.00119-23","DOIUrl":"https://doi.org/10.1128/jmbe.00119-23","url":null,"abstract":"ABSTRACT Course-based undergraduate research experiences (CUREs) are increasingly becoming the first, and perhaps only, research experience for many biology students. Responsible and ethical conduct of research (RECR) is crucial for the integrity of scientific research and essential for students to have an understanding of the scientific process at any academic level. However, there is a current lack of RECR education in biology CUREs. To understand the level of RECR knowledge and skills in undergraduate students, we created a diagnostic survey that uses case scenarios designed to illustrate RECR issues in the CURE classroom. Analysis of students’ responses indicated that the overall percentage of students who are able to effectively use RECR terminology and identify the impact of RECR violations on science integrity and ultimately on society is low. Furthermore, some students equated RECR violations to academic dishonesty, indicating difficulties separating the research and academic aspects of CUREs. This diagnostic tool can aid instructors in identifying gaps in student RECR knowledge for the subsequent development of RECR educational interventions, particularly to ensure the integrity of the research performed in CURE settings.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135858101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Lockdown! Learning public health of infectious diseases through gameplay 封锁!通过游戏学习传染病的公共卫生知识

Journal of Microbiology & Biology Education Pub Date : 2023-10-04 DOI: 10.1128/jmbe.00095-23

Evelyn Goh, Anna Szücs, Victor Weng Keong Loh, Yann Felix Boucher

引用次数: 0

Increasing student interest with the Bacterial Unknown Identification Project: using mixed cultures to create real-world applications 增加学生对未知细菌鉴定项目的兴趣:使用混合培养来创建实际应用

Journal of Microbiology & Biology Education Pub Date : 2023-10-04 DOI: 10.1128/jmbe.00070-23

Kayla Perri, Maha Abdelhaseib, Ashwana D. Fricker

{"title":"Increasing student interest with the Bacterial Unknown Identification Project: using mixed cultures to create real-world applications","authors":"Kayla Perri, Maha Abdelhaseib, Ashwana D. Fricker","doi":"10.1128/jmbe.00070-23","DOIUrl":"https://doi.org/10.1128/jmbe.00070-23","url":null,"abstract":"ABSTRACT Many introductory-level classes teach fundamental concepts, as they are prerequisites for upper-division courses. Therefore, the student body in these classes has diverse interests. To address this breadth of career trajectory, introductory-level laboratory courses often include experiments that demonstrate a wide range of microbiological techniques and processes. One of the experiments that is a standard component of many microbiology classes, the Bacterial Unknown Identification Project (BUIP), is often limited to isolated organisms or a specific environment. Here, we describe an updated method for the BUIP that incorporates the projected student career diversity through the implementation of multiple mixed cultures of microorganisms associated with different environments. This update can be utilized in any microbiology laboratory classroom. We maintained the learning objectives, including applying appropriate microbiological methods to analyze and interpret results, and effectively communicate scientific findings, while modifying the sample composition. Assessment of the modification demonstrated that upon completion of the BUIP, students felt that the project applied to their career and it did not take too much of their free time to complete.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135592435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teaching transferable skills in teamwork, accountability, goal setting, writing, and problem-solving in a non-major microbiology lab: the unknown bacteria experiment redefined 在非主要微生物实验室教授团队合作、责任、目标设定、写作和解决问题的可转移技能:重新定义未知细菌实验

Journal of Microbiology & Biology Education Pub Date : 2023-10-04 DOI: 10.1128/jmbe.00135-23

Felicia McKee, Josef D. Wolf, Samantha Simon, Jeanetta H. Floyd

引用次数: 0

Helping students see bacteria in 3D: cellular models increase student learning about cell size and diffusion 帮助学生在3D中看到细菌:细胞模型增加了学生对细胞大小和扩散的学习

Journal of Microbiology & Biology Education Pub Date : 2023-10-03 DOI: 10.1128/jmbe.00089-23

Emily M. Wollmuth, Alberto Correa, Manuela Alvarado Obando, Michelle K. Smith, Daniel H. Buckley, Kathleen L. Hefferon, Esther R. Angert

{"title":"Helping students see bacteria in 3D: cellular models increase student learning about cell size and diffusion","authors":"Emily M. Wollmuth, Alberto Correa, Manuela Alvarado Obando, Michelle K. Smith, Daniel H. Buckley, Kathleen L. Hefferon, Esther R. Angert","doi":"10.1128/jmbe.00089-23","DOIUrl":"https://doi.org/10.1128/jmbe.00089-23","url":null,"abstract":"ABSTRACT In the microbial world, cell size and shape impact physiology, but students struggle to visualize spatial relationships between cells and macromolecules. In prokaryotic cells, cell size is limited by reliance on diffusion for nutrient uptake and the transport of nutrients within the cell. Cells must also meet a minimum size threshold to accommodate essential cellular components such as ribosomes and DNA. Using 3D printing allows for the creation of custom models that can be influential teaching tools in the biology classroom. This lesson uses 3D cell models to teach students enrolled in an introductory microbiology course about bacterial cell size and the biological importance of surface-area-to-volume ratio. During the lesson, students interact with 3D cell models and discuss a series of questions in small groups. Student learning was assessed using quantitative and qualitative student response data collected pre- and post-lesson. Student achievement of learning objectives, and their confidence in their knowledge of these concepts, improved post-lesson, and these gains were statistically significant. Our findings suggest that interacting with 3D-printed cell models improves student understanding about bacterial cell size and diffusion.","PeriodicalId":46416,"journal":{"name":"Journal of Microbiology & Biology Education","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135696633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ten tips for developing a more inviting syllabus 制定更具吸引力的教学大纲的10个建议

Journal of Microbiology & Biology Education Pub Date : 2023-10-03 DOI: 10.1128/jmbe.00032-23

Shelby Chandar, Ryan Crum, Eric Pennino, Cathy Ishikawa, Sayonita Ghosh Hajra, Kelly McDonald

引用次数: 0