Trends in Psychiatry and Psychotherapy最新文献

{"title":"Clinical Interplay Between Autism Spectrum Disorder and Bipolar Disorder: A Narrative Review.","authors":"Mirela Paiva Vasconcelos-Moreno, Daniel Prates-Baldez, Júlio Santos-Terra, Iohanna Deckmann, Isabella Naomi Di Gesu, Renata de Sanson Lemann, Rudimar Riesgo, Carmem Gottfried, Flávio Kapczinski","doi":"10.47626/2237-6089-2024-0939","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0939","url":null,"abstract":"<p><strong>Introduction: </strong>Autism Spectrum Disorder (ASD) and Bipolar Disorder (BD) present significant challenges in diagnosis due to their complex nature. This review aims to examine the interface and overlapping features of these conditions.</p><p><strong>Methods: </strong>We conducted a narrative review to examine clinical overlap, common psychiatric comorbidities, and shared neurobiological bases between ASD and BD.</p><p><strong>Results: </strong>There is a notable convergence of symptoms in ASD and BD, including mood instability and emotional dysregulation; irritability, impulsivity, and aggressive behavior; deficits in social skills and social cognition; impairments in executive functions; sleep disturbances; problematic sexual behaviors; and sensory sensitivities. Common psychiatric comorbidities and shared neurobiological basis further underscore this potential interplay.</p><p><strong>Conclusion: </strong>Despite distinct clinical trajectories and diagnostic criteria, our findings indicate a significant overlap in symptoms and clinical presentations between ASD and BD. This complexity makes it challenging to identify the co-occurrence of ASD and BD, which can lead to difficulties in accurately diagnosing and managing both conditions simultaneously.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Worry related to climate change in Brazilian adults.","authors":"Maria Nieves, Karen Jansen","doi":"10.47626/2237-6089-2024-0905","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0905","url":null,"abstract":"<p><strong>Introduction: </strong>Climate change is happening, and feeling anxiety can be seen as a natural response to it. Climate anxiety is the worry about the climate crisis and could be related to specific emotions and thoughts. The aim of this study was to assess the prevalence of worry about climate change, and to describe the emotions and thoughts associated to it in Brazilian adults.</p><p><strong>Method: </strong>Cross-sectional study with participants aged between 18-42 years (n=323). Data were collected online using the questionnaire developed by Hickman and colleagues, which assesses the worry, thoughts and feelings about climate change.</p><p><strong>Results: </strong>88.5% were worried about climate change. The feelings of sadness, powerlessness, fear and anxiety were reported more often among those who were worried. The most frequent thoughts were: \"People have failed to take care of the planet\", \"The future is frightening\", \"My family's security will be threatened\" and \"Humanity is doomed\".</p><p><strong>Discussion: </strong>In this sample, the majority of the individuals were concerned about climate change, and they showed more negative emotions and thoughts when compared to individuals that were not concerned. Future studies should take care to not understand natural worries and anxiety responses to climate change as pathological.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are parents with bipolar disorder at higher risk of having offspring with ADHD? A systematic review.","authors":"Leandro L Ferreira, Antonio E Nardi, Laiana A Quagliato","doi":"10.47626/2237-6089-2024-0797","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0797","url":null,"abstract":"<p><strong>Background: </strong>The offspring of parents with bipolar disorder (BD) and with attention deficit hyperactivity disorder (ADHD) have a higher risk of having the same condition. Both disorders also share psychopathological symptoms; however, little is known about their genetic overlap. To examine whether the offspring of parents with BD have a greater chance of being affected by ADHD, we conducted a systematic review.</p><p><strong>Methods: </strong>From inception to August 12, 2024, we searched the PubMed, SciELO, PsycInfo and Cochrane databases. We included studies if they investigated the association of parental bipolar disorder with offspring outcomes and made a proper investigation of disorders using validated instruments based on the Diagnostic Statistical Manual of Mental Disorders (DSM) or the International Classification of Diseases (ICD) criteria. Studies were excluded if: parents were under 18 years old or over 70; did not report original data; systematic reviews; in vitro studies; with an animal model; offspring older than 17 years of age or with any comorbid diagnosis with ADHD. To assess risk of bias, two authors independently used the Newcastle-Ottawa Scale quality assessment tool.</p><p><strong>Results: </strong>23 articles met the inclusion criteria. The majority of the studies reported that the offspring of parents with BD were at higher risk for ADHD. Particularly, in all case‒control studies, the risk of ADHD was higher in the case group than the control group.</p><p><strong>Conclusion: </strong>The current studies are yet heterogeneous and literature did not uncover the biological correlation of these disorders regarding genetic, biochemical, neuroimaging and neuropsychological aspects.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Hippocrates to the Ages of Technology: A Narrative Review of the Evolution of the doctor-patient Relationship.","authors":"Isabela Azeredo Melca, Rachel Moraes Ferreira, Antonio Egídio Nardi, Anna Lucia Spear King","doi":"10.47626/2237-6089-2024-0934","DOIUrl":"https://doi.org/10.47626/2237-6089-2024-0934","url":null,"abstract":"<p><strong>Objectives: </strong>Thus, through a narrative review, this article analyzes how the advancement of technology, the use of digital resources, and social media have impacted the doctor-patient relationship.</p><p><strong>Methods: </strong>We conducted a scoping review on the relationship between Digital Health Equity and Telemedicine and e-health via Scopus and Pubmed electronic databases. The following inclusion criteria were established: papers on the relationship between digital health equity and telemedicine and e-health, written in English and with no time limits. All study designs were eligible, including those that have utilized qualitative and quantitative methods, methodology, or guidelines reports, except for meta-reviews.</p><p><strong>Results: </strong>With the advancement of technology and social media, a change in behavior in the population and the doctor-patient relationship was observed. Through the help of digital devices, the increased prevalence of social networks, and asynchronous consultations new opportunities were created to bring doctors and patients closer. The relationship has shifted from face-to-face and paternalistic to virtual communication with shared decisions in recent decades. It was observed that the advancement of technology and the use of digital resources have reshaped the roles of doctors and patients and their relationships.</p><p><strong>Conclusion: </strong>Technology is the leading cause for an informed, more involved, and responsible patient. However, physicians have conflicting opinions about the use of these technologies. While recognizing its benefits for patients, they are also concerned about digital health and its impact.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional impairment and post-stroke depression: a 6-month longitudinal study.","authors":"Larissa P Borlina Beltrami, Paula Teixeira Marques, Francisco Jaime Lopes Barbosa, Viviane H Flumignan Zetola, Marcos Christiano Lange, Raffael Massuda","doi":"10.47626/2237-6089-2022-0589","DOIUrl":"10.47626/2237-6089-2022-0589","url":null,"abstract":"<p><strong>Objective: </strong>In recent decades, there have been considerable advances in treatment and prevention of acute ischemic stroke (IS). However, even after treatment, approximately two-thirds of patients with IS have some degree of disability that requires rehabilitation, along with an increased likelihood of developing psychiatric disorders, particularly depression. The objective of this study was to determine the predictors of post-stroke depression in a 6-month period in patients with IS.</p><p><strong>Methods: </strong>Ninety-seven patients with IS without previous depression were included in the study. The study protocol was applied during hospitalization and at 30, 90, and 180 days after hospital discharge. A binary logistic regression was then conducted. Age, sex, marital status, occupation, educational level, thrombolysis, National Institute of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS) score, Barthel Index (BI), and Mini-Mental State Examination (MMSE) score were included as independent variables.</p><p><strong>Results: </strong>Of the 97 patients, 24% of patients developed post-stroke depression. In the longitudinal follow-up, an mRS score of > 0 was the lone significant predictor of development of depression (odds ratio [OR] = 5.38; 95% confidence interval [95%CI] 1.25-23.12; p < 0.05).</p><p><strong>Conclusion: </strong>Our results showed that in patients without previous depression, functional impairment of any degree is associated with a 5-fold greater chance of development of depression in the first 6 months post-stroke compared to patients without functional impairment.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20220589"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9248976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the use of lithium for suicidality in acute settings: rationale, risks, and uncertainties.","authors":"Rafael Ramos Amaral, Pedro V S Magalhães","doi":"10.47626/2237-6089-2024-0811","DOIUrl":"10.47626/2237-6089-2024-0811","url":null,"abstract":"<p><p>Lithium's well-documented efficacy in preventing suicide over the long term prompts consideration of its potential for more rapid antisuicidal effects. However, evidence supporting such acute efficacy is limited. Weighing against its possible rapid benefits are significant concerns regarding lithium's side-effect profile - particularly toxicity, renal impairment, and weight gain - and the often necessary delay in achieving therapeutic levels. Moreover, the multifaceted nature of suicidality complicates identifying short-term outcomes and disentangling lithium's effects on suicidal thoughts from broader reductions in depressive symptoms. While lithium may remain invaluable for some high-risk patients in emergency settings, its routine use as a rapid-acting agent for acute suicidality is currently not well supported.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20240811"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of stakeholder interests on safety outcome reporting in psychedelic research and implications for science communication.","authors":"Elena Koning, Marco Solmi, Elisa Brietzke","doi":"10.47626/2237-6089-2024-0866","DOIUrl":"10.47626/2237-6089-2024-0866","url":null,"abstract":"<p><p>Psychedelics are a group of psychoactive substances that produce complex and subjective changes to consciousness and carry unique safety considerations. There is a growing body of work investigating the use of psychedelics in mental health treatment alongside increasing socio-cultural and political acceptance. This rapid evolution has prompted corporations to fund psychedelic clinical trials, leading to a potential rise in conflicts of interest in relevant studies and publications. However, the body of evidence for the safety and efficacy of psychedelic-assisted psychotherapy is early. There is concern regarding the introduction of bias in psychedelic clinical trials and the selective reporting of results amidst and beyond corporate involvement. At a crucial time in psychedelic drug reform, this paper explores the safety concerns associated with psychedelics, the potential influences of financial stakeholders on safety outcome reporting and the importance of balanced science communication in maintaining public health and safety.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20240866"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the intensity of dissociation predict antidepressant effects 24 hours after infusion of racemic ketamine or esketamine in treatment-resistant depression? A secondary analysis from a randomized controlled trial.","authors":"Mariana V F Echegaray, Rodrigo P Mello, Guilherme M Magnavita, Gustavo C Leal, Fernanda S Correia-Melo, Ana Paula Jesus-Nunes, Flávia Vieira, Igor D Bandeira, Ana Teresa Caliman-Fontes, Manuela Telles, Lívia N F Guerreiro-Costa, Roberta Ferrari Marback, Breno Souza-Marques, Daniel H Lins-Silva, Cassio Santos-Lima, Taiane de Azevedo Cardoso, Flávio Kapczinski, Acioly L T Lacerda, Lucas C Quarantini","doi":"10.47626/2237-6089-2022-0593","DOIUrl":"10.47626/2237-6089-2022-0593","url":null,"abstract":"<p><strong>Objective: </strong>Ketamine and esketamine have both shown significant antidepressant effects in treatment-resistant depression (TRD) and conflicting evidence suggests that dissociation induced by these drugs could be a clinical predictor of esketamine/ketamine's efficacy.</p><p><strong>Methods: </strong>This study is a secondary analysis of data from a two-center, randomized, controlled trial. Participants were randomly assigned 1:1 to receive an IV infusion of either esketamine (0.25 mg/kg) or racemic ketamine (0.50 mg/kg) over 40 minutes. Dissociative symptoms were assessed using the Clinician-Administered Dissociative State Scale (CADSS) 40 minutes following the beginning of the infusion. Variations in depression scores were measured with the Montgomery-Åsberg Depression Rating Scale (MADRS), which was administered before the intervention as a baseline measure and 24 hours, 72 hours, and 7 days following infusion.</p><p><strong>Results: </strong>Sixty-one patients were included in the analysis. Examining CADSS scores of 15 or below, for every 1-point increment in the CADSS score, there was a mean change of -0.5 (standard deviation [SD] = 0.25; p = 0.04) of predicted MADRS score from baseline to 24 hours. The results for 72 hours and 7 days following infusion were not significant. Since the original trial was not designed to assess the relationship between ketamine or esketamine-induced dissociation and antidepressant effects as the main outcome, confounding variables for this relationship were not controlled.</p><p><strong>Conclusion: </strong>We suggest a positive relationship between dissociation intensity measured with the CADSS and the antidepressant effects of ketamine and esketamine 24 hours after infusion for CADSS scores of up to 15 points.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20220593"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10633570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile dating app use and sexual risk behavior among Brazilian undergraduate students.","authors":"Edson Zangiacomi Martinez, Vitoria de Souza Pinto Frazatto, Jonathan Leonardo Gonçalves Prudencio, Guilherme Galdino, Miriane Lucindo Zucoloto","doi":"10.47626/2237-6089-2023-0746","DOIUrl":"10.47626/2237-6089-2023-0746","url":null,"abstract":"<p><strong>Objective: </strong>One of the most popular ways to meet new people in the modern world is through dating apps. However, their use may facilitate casual sexual encounters and quick partner changes, both of which are associated with endangering sexual health in different populations. The objective of this study is to describe the use of mobile dating apps among undergraduate students at a major Brazilian public university and investigate its associations with sexual risk behaviors and sociodemographic factors.</p><p><strong>Methods: </strong>This is a cross-sectional study based on a web survey. The link for participation was made available to students enrolled in undergraduate courses at the eight units of Universidade de São Paulo, Campus Ribeirão Preto. Use of dating apps, sociodemographic/behavioral profile, and sexual risk behaviors were among the variables studied. The distribution of app users was calculated for each variable of interest, and prevalence ratios (PRs) were used for comparisons. PRs were reported with 95% confidence intervals (95%CI).</p><p><strong>Results: </strong>A total of 487 students participated, with 32.9% reporting using dating apps. Male participants were more likely to use apps. Use of dating apps was associated with having multiple sexual partners and risky behaviors such as smoking, alcohol consumption, and substance abuse.</p><p><strong>Conclusion: </strong>It is critical to describe the pattern of app use by undergraduate students and understand its influence on sexual health in order to avoid stigmatizing users. Additionally, this information can be helpful to guide the creation of strategies for using these apps as resources to promote health, such as through sharing information regarding sexual health.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20230746"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroscience-based nomenclature (NbN): the Portuguese version of the new classification for psychopharmacological drugs.","authors":"José Carlos Fernandes Galduróz, Aleksander Roberto Zampronio, Maria Aparecida Barbato Frazão Vital, Paulo Clemente Sallet, Joseph Zohar, Roberto Andreatini","doi":"10.47626/2237-6089-2023-0771","DOIUrl":"10.47626/2237-6089-2023-0771","url":null,"abstract":"<p><p>Neuroscience-based nomenclature (NbN) is a proposal to provide a nomenclature based on neuroscience and pharmacology instead of the old disease-based classification. The NbN is based on the mechanism of action and pharmacological target and aims to assist in rational prescription, to reduce stigma, and to increase treatment adherence. Currently, the NbN is endorsed by many psychiatric associations, has been adopted by several relevant journals, and is included in major psychiatry textbooks. Therefore, it is important that the NbN is known to psychiatrists.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20230771"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}