Trends in Psychiatry and Psychotherapy最新文献

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New insights into susceptibility to major depression in a Colombian population. 哥伦比亚人群对重度抑郁症易感性的新见解。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-03-15 DOI: 10.47626/2237-6089-2025-1095
Jesús Montoya, Laura I Rojas-Serrano, Daniel A Ruiz-Torres, Nicolas Caicedo, Isabella Van Londoño, Caroll Tamayo, Juan C Rojas-Lopez, Marcela Galvez, Nora Contreras, Rafael Tierradentro, Laura Castro, Natalia Fonseca, Dora J Fonseca-Mendoza
{"title":"New insights into susceptibility to major depression in a Colombian population.","authors":"Jesús Montoya, Laura I Rojas-Serrano, Daniel A Ruiz-Torres, Nicolas Caicedo, Isabella Van Londoño, Caroll Tamayo, Juan C Rojas-Lopez, Marcela Galvez, Nora Contreras, Rafael Tierradentro, Laura Castro, Natalia Fonseca, Dora J Fonseca-Mendoza","doi":"10.47626/2237-6089-2025-1095","DOIUrl":"https://doi.org/10.47626/2237-6089-2025-1095","url":null,"abstract":"<p><strong>Objective: </strong>Major Depressive Disorder (MDD) is a multifactorial psychiatric disease influenced by a combination of genetic and environmental factors. Among the genes linked to MDD, the Melanocortin 1 Receptor (MC1R), Catechol-O-Methyltransferase (COMT), Brain-Derived Neurotrophic Factor (BDNF), and the serotonin transporter (5-HTT) are of particular interest due to their critical roles in stress regulation and neural function. Despite their biological significance, the contribution of specific polymorphisms within these genes to MDD risk remains understudied.</p><p><strong>Methods: </strong>This retrospective observational case-control study included 87 Colombian patients diagnosed with MDD according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). The control group comprised Latino/admixed individuals without, sourced from the gnomAD v2.1.1 database. The complete coding region of the MC1R gene and three polymorphisms: 5-HTTLPR Insertion/Deletion 44 bp, BDNF-c.196G>A, and COMT-c.472G>A were genotyped using PCR and Sanger sequencing.</p><p><strong>Results: </strong>The polymorphisms rs885479 and rs4680 were identified as protective factors against MDD, while the polymorphisms rs796296176, rs779504604, rs1805005 were associated with an increased risk of developing MDD (OR:22.87, OR:51.26, OR: 1.97, respectively).</p><p><strong>Conclusion: </strong>Several of the analyzed polymorphisms (rs796296176, rs779504604, rs1805005) increase the risk for MDD. Notably, we provide novel evidence of these polymorphisms in MC1R as a risk to MDD.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of autism in African countries: a systematic review and meta-analysis. 非洲国家自闭症患病率:系统回顾和荟萃分析。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-02-04 DOI: 10.47626/2237-6089-2025-1251
Inácio Luís Ferreira, João Viriato Mazalo, Daniel Prates-Baldez, Flávio Kapczinski, Lucas C Quarantini
{"title":"Prevalence of autism in African countries: a systematic review and meta-analysis.","authors":"Inácio Luís Ferreira, João Viriato Mazalo, Daniel Prates-Baldez, Flávio Kapczinski, Lucas C Quarantini","doi":"10.47626/2237-6089-2025-1251","DOIUrl":"https://doi.org/10.47626/2237-6089-2025-1251","url":null,"abstract":"<p><strong>Background: </strong>Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by difficulties in communication, deficits in social interaction, and repetitive behavioral patterns. Global prevalence estimates range from 1% to 2%, with variations attributed to cultural, social, and methodological factors. In Africa, research remains limited and highly heterogeneous, largely due to scarce diagnostic resources, persistent stigma, and the absence of consistent public policies.</p><p><strong>Methods: </strong>A systematic search was conducted across PubMed, Embase, Scopus, and PsycInfo for articles published up to May 2025. Cross-sectional studies conducted in school-based or community populations were included. The analysis followed PRISMA guidelines, and the protocol was registered with PROSPERO (CRD420251138668). A random-effects model using the Freeman-Tukey transformation for variance stabilization was employed for statistical synthesis.</p><p><strong>Results: </strong>Seven studies from Egypt, Kenya, Uganda, and Nigeria, comprising 71,341 participants, were included. Across included studies, reported ASD prevalence ranged from 0.54% to 23.8%. When pooled and stratified by methodological criteria, clinically confirmed ASD prevalence was 1% (95% CI, 0.0-1.0%), whereas high-risk screening prevalence was 4% (95% CI, 0.0-16.0%), with very high between-study heterogeneity (I² = 99.8%).</p><p><strong>Conclusion: </strong>Despite substantial methodological heterogeneity, ASD prevalence estimates in Africa appear comparable to those reported in high-income countries. The marked disparity between high-risk screening prevalence and confirmed diagnoses highlights the urgent need to expand diagnostic confirmation services and strengthen training for primary healthcare professionals to bridge the gap between risk identification and definitive diagnosis across the continent.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Co-occurring mental health disorders in a Brazilian sample of adults with autism spectrum disorder: A focus on gender disparities. 在巴西患有自闭症谱系障碍的成人样本中共同发生的精神健康障碍:对性别差异的关注。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-21 DOI: 10.47626/2237-6089-2025-1229
João Victor Betti Paiva, Helena de Souza Beserra Silva, Rosane Lowenthal, Tatiana Pontrelli Mecca
{"title":"Co-occurring mental health disorders in a Brazilian sample of adults with autism spectrum disorder: A focus on gender disparities.","authors":"João Victor Betti Paiva, Helena de Souza Beserra Silva, Rosane Lowenthal, Tatiana Pontrelli Mecca","doi":"10.47626/2237-6089-2025-1229","DOIUrl":"https://doi.org/10.47626/2237-6089-2025-1229","url":null,"abstract":"<p><strong>Introduction: </strong>Adults with Autism Spectrum Disorder (ASD) often present with core symptoms and co-occurring conditions that require multidisciplinary support. The objective of this study is to describe the sociodemographic and clinical profile of a sample of Brazilian adults with ASD, with a focus on the prevalence of co-occurring mental health disorders and the investigation of gender-related disparities.</p><p><strong>Methods: </strong>A total of 117 adults with a previous diagnosis of ASD (60.7% female; mean age = 31.84, SD = 10.03; age range: 18-61 years) were recruited by convenience sampling. Participants completed a sociodemographic and clinical history questionnaire. We analyzed associations between co-occurring mental health disorders and biological sex.</p><p><strong>Results: </strong>Most participants had completed at least high school (95.7%). Co-occurring neurodevelopmental disorders were present in 35.9% of the sample. ADHD was the most common (30.8%). Co-occurring mental health disorders were reported by 75.2% of participants, with anxiety disorders being the most frequent (71.8%). A statistically significant gender disparity was observed, showing that women had a significantly higher prevalence of at least one mental health disorder (85.9% vs. 58.7%), anxiety (83.1% vs. 54.3%), and depression (62% vs. 37%) compared to men.</p><p><strong>Conclusion: </strong>While not generalizable due to the convenience sampling method, these results contribute to a growing body of evidence on the high rates of co-occurring mental health disorders in adults with ASD, especially in women. This study supports the call for an expanded research agenda in Brazil to better understand the clinical reality and guide future support strategies for this population.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a single-session facial emotion recognition training using the MTS paradigm in cognitively unimpaired older adults. 使用MTS范式的单次面部情绪识别训练在认知功能未受损的老年人中的效果。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-06 DOI: 10.47626/2237-6089-2025-1082
Marcos Hortes N Chagas, Bianca Leticia C C Ferreira, Laura Lobrigatti Pelaes, Ana Julia L Bomfim
{"title":"Effects of a single-session facial emotion recognition training using the MTS paradigm in cognitively unimpaired older adults.","authors":"Marcos Hortes N Chagas, Bianca Leticia C C Ferreira, Laura Lobrigatti Pelaes, Ana Julia L Bomfim","doi":"10.47626/2237-6089-2025-1082","DOIUrl":"https://doi.org/10.47626/2237-6089-2025-1082","url":null,"abstract":"<p><strong>Introduction: </strong>Facial emotion recognition (FER) is the ability to interpret the feelings and emotions of others. Given the decline in FER ability observed in older adults, intervention studies to assess the effects of training this skill are essential. Therefore, this study aims to evaluate the effects of FER training in cognitively unimpaired older adults.</p><p><strong>Method: </strong>A randomized, crossover clinical trial was conducted. Twenty-two individuals aged 60 years or older, without indications of depression or cognitive decline, were selected. Participants completed one session of FER training and one control training session through a Matching-to-Sample (MTS) procedure on a portable touchscreen computer, with a seven-day interval between sessions. The primary outcomes were total accuracy and accuracy by emotion in two FER tasks, using dynamic and static stimuli.</p><p><strong>Results: </strong>In the dynamic stimuli task, repeated-measures ANOVA revealed significant differences in overall emotion accuracy (F2,40 = 4.592; p = 0.016; η²p = 0.187). Bonferroni post hoc analysis indicated improvement following FER training compared to baseline (p = 0.004). Additionally, ANOVA showed improved recognition of happiness (F2,40 = 7.732; p = 0.001; η²p = 0.279) following FER training compared to control training. Regarding the static stimuli task, ANOVA revealed significant differences in scores only for disgust (F2,40 = 5.748; p = 0.006; η²p = 0.223), with improvement following FER training compared to baseline (p = 0.005).</p><p><strong>Conclusion: </strong>FER training increased overall performance accuracy, particularly for happiness and disgust. Future studies involving multiple training sessions, larger sample sizes, and clinical populations are essential for the generalization of these findings.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nonsuicidal self-injury behavior and internet use profile in undergraduate students: a cross-sectional study. 大学生非自杀自伤行为与网络使用概况:一项横断面研究。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-05 DOI: 10.47626/2237-6089-2025-1122
Bárbara Evelline da Silva Bandeira, Amilton Dos Santos, Eloisa Helena Valler Rubello Celeri
{"title":"Nonsuicidal self-injury behavior and internet use profile in undergraduate students: a cross-sectional study.","authors":"Bárbara Evelline da Silva Bandeira, Amilton Dos Santos, Eloisa Helena Valler Rubello Celeri","doi":"10.47626/2237-6089-2025-1122","DOIUrl":"https://doi.org/10.47626/2237-6089-2025-1122","url":null,"abstract":"<p><strong>Objective: </strong>The objective of the present study was to describe and analyze the characteristics of internet use in undergraduate students that engaged in nonsuicidal self-injury (NSSI) compared with individuals not engaging in this behavior.</p><p><strong>Methods: </strong>An observational cross-sectional study was conducted. The questionnaire used to investigate NSSI was devised based on the DSM5 diagnostic criteria. Internet use was investigated using 2 questionnaires: a questionnaire developed by the researchers; and the Portuguese version of the Internet Addiction Test (IAT). Exploratory analysis of data was performed based on summary measures. Mann-Whitney and chi-square tests were employed, and multiple logistic regression models constructed with stepwise variable selection criteria. A 5% level of significance was adopted.</p><p><strong>Results: </strong>Data on 6,906 university students were analyzed, 1,188 (17%) of whom reported at least one NSSI episode in their lifetime. The group engaging in self-injurious behavior showed a stronger association with more intense internet use than they would like and felt they related more with individuals online than in person. The group engaging in self-injurious behavior reported using the internet more often to meet new people for friendships and for erotic relationships and preferred the excitement of the internet to intimacy with a partner.</p><p><strong>Conclusion: </strong>The feeling of loneliness linked to self-injurious behavior might contribute to self-injurers seeking relationships online. Also, the anonymous nature of online interactions may constitute an attractive environment for expressing psychological anguish and other emotional problems. As a study limitation, this is a cross-sectional design in which associations are identified, but risk factors cannot be established.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145906816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PID-5-SRF online administration: psychometric indicators and measurement invariance between different formats of data collection. PID-5-SRF 在线管理:不同数据收集格式之间的心理测量指标和测量不变性。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-01 Epub Date: 2024-05-28 DOI: 10.47626/2237-6089-2023-0711
Ana Maria Barchi-Ferreira, Flavia L Osório
{"title":"PID-5-SRF online administration: psychometric indicators and measurement invariance between different formats of data collection.","authors":"Ana Maria Barchi-Ferreira, Flavia L Osório","doi":"10.47626/2237-6089-2023-0711","DOIUrl":"10.47626/2237-6089-2023-0711","url":null,"abstract":"<p><strong>Objective: </strong>The Personality Inventory for DSM-5 (PID-5) is a tool used to assess maladaptive personality traits according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) alternative model. The objective is to seek evidence of the validity and reliability of the PID-5 - Self Reported Form (PID-5-SRF) administered online and assess its measurement invariance compared to the paper-and-pencil administration.</p><p><strong>Method: </strong>A sample of 274 individuals from the general population (73.4% of women; 34.76 years old ± 11.6) completed the instrument online after the study was disseminated on social media and among the authors' contacts.</p><p><strong>Results: </strong>Internal consistency (facets α ≥ 0.70; domains α ≥ 0.89) and test-retest reliability (15 to 30 days: facets intraclass correlation coefficient [ICC] ≥ 0.63; domains ICC ≥ 0.82) were satisfactory, but a floor effect was found in almost all the items. A large number of facets (n = 9) showed better fit to a bifactorial structure, and the exploratory factor analysis (EFA) suggested that a six-factor model better fits the data. Measurement invariance between the online and paper-and-pencil administrations was not attested at a configural level.</p><p><strong>Conclusion: </strong>The results revealed satisfactory psychometric indicators when the instrument was applied online, confirming its feasibility in collecting data. However, the instrument's structure is not invariant, and caution must be adopted when comparing and interpreting data collected through different formats.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20230711"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Portuguese-language content about autism spectrum disorder on YouTube: a cross-sectional study. YouTube 上有关自闭症谱系障碍的葡萄牙语内容:一项横断面研究。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-01 Epub Date: 2024-09-05 DOI: 10.47626/2237-6089-2024-0884
Isabella Paixão, Fagner Sutel de Moura, Leonardo Pestillo de Oliveira, Lucas França Garcia
{"title":"Portuguese-language content about autism spectrum disorder on YouTube: a cross-sectional study.","authors":"Isabella Paixão, Fagner Sutel de Moura, Leonardo Pestillo de Oliveira, Lucas França Garcia","doi":"10.47626/2237-6089-2024-0884","DOIUrl":"10.47626/2237-6089-2024-0884","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the quality and reliability of information about autism spectrum disorder (ASD) available in Portuguese on YouTube, based on the growing demand for accessible information about ASD and the relevance of digital platforms as sources of health information.</p><p><strong>Methods: </strong>Using a cross-sectional observational study design, videos published in the last 5 years with more than 50,000 views were selected. The analysis consisted of two stages: characterization of the profile of the selected videos and assessment of information quality with the DISCERN Questionnaire.</p><p><strong>Results: </strong>A total of 48 videos, predominantly produced by healthcare providers and educators, were analyzed. The content of videos made by professionals was of higher quality and reliability compared to videos posted by laypersons and news reports. These findings highlight expertise in the field as a critical determinant of content quality, stressing the importance of relying on expert sources when disseminating information about ASD. The ICD-10 and DSM-V were rarely mentioned, especially in videos by non-professionals, which is indicative of challenges in conveying diagnostic information.</p><p><strong>Conclusions: </strong>The findings of this study demonstrate the significant potential of YouTube as an educational tool to raise ASD awareness, but also highlight the need for a collaborative approach between content creators, healthcare providers, educators, and policymakers to ensure that the information made available is reliable, accurate, and of high quality. Therefore, we recommend the development of specific guidelines for content creators and the implementation of verification mechanisms for YouTube channels run by subject matter experts.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20240884"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Celebrating scientific curiosity: 75th anniversary of the unexpected way lithium revolutionized psychopharmacology. 庆祝科学好奇心:锂以出人意料的方式彻底改变精神药理学 75 周年。
IF 3
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-01 Epub Date: 2024-09-25 DOI: 10.47626/2237-6089-2024-0894
Marcela Carbajal-Tamez, Elizabeth Monday, João Quevedo
{"title":"Celebrating scientific curiosity: 75th anniversary of the unexpected way lithium revolutionized psychopharmacology.","authors":"Marcela Carbajal-Tamez, Elizabeth Monday, João Quevedo","doi":"10.47626/2237-6089-2024-0894","DOIUrl":"10.47626/2237-6089-2024-0894","url":null,"abstract":"","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20240894"},"PeriodicalIF":3.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between nucleus accumbens volume and substance use disorder: a narrative review. 伏隔核体积与物质使用障碍的关系:一个叙述性的回顾。
IF 3
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-01 Epub Date: 2025-05-11 DOI: 10.47626/2237-6089-2025-1046
Érico de Carvalho Leitão Pimentel, Gabriel Moreli Ribeiro, Larissa de Goes, Elaine Minatel, Anderson Ravy Stolf, Fabiano Reis
{"title":"Association between nucleus accumbens volume and substance use disorder: a narrative review.","authors":"Érico de Carvalho Leitão Pimentel, Gabriel Moreli Ribeiro, Larissa de Goes, Elaine Minatel, Anderson Ravy Stolf, Fabiano Reis","doi":"10.47626/2237-6089-2025-1046","DOIUrl":"10.47626/2237-6089-2025-1046","url":null,"abstract":"<p><strong>Introduction: </strong>The nucleus accumbens (NAc) is central to the brain's reward circuitry, mediating motivation and emotional processes. Emerging evidence suggests that structural and functional changes in the NAc, including volume alterations, may contribute to the neuropathology of substance use disorder (SUD). This review evaluates current findings on the association between NAc volumetric changes depicted by magnetic resonance imaging (MRI) and SUD.</p><p><strong>Methods: </strong>A literature search was conducted in PubMed, EMBASE, BVS, Web of Science, Scopus, Cochrane Library, and PsycInfo. Terms used in searches included Nucleus Accumbens, Mental Disorder, Substance Use Disorder, Drug Addiction, and Magnetic Resonance Imaging (MRI). The main findings from the selected studies were synthesized in a table.</p><p><strong>Results: </strong>The initial database searches yielded 3686 articles. After screening, duplicate articles, non-English/Spanish/Portuguese articles, animal studies, and studies that did not address SUD were excluded. Additional exclusion criteria included studies involving only familial risk of substance use or abstinence, as well as studies without NAc analysis or structural MRI analysis. 52 cross-sectional studies regarding associations between NAc volumes and SUDs were selected.</p><p><strong>Conclusion: </strong>The reviewed studies suggest that NAc volumetric alterations may play a pivotal role as an associated factor in addiction, with strong associations mainly to cigarette smoking and alcohol use. Other substances show inconsistent findings. Discrepancies in results may reflect differences in study designs, the type of volumetric analysis employed, and control over confounding variables. Future studies that use multimodal approaches and control for confounding variables are required to strengthen these associations.</p>","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20251046"},"PeriodicalIF":3.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actions and joint efforts of a public school of medicine to promote health and well-being during a climate disaster: a journey toward community resilience. 一所公立医学院在气候灾难期间促进健康和福祉的行动与共同努力:社区抗灾之旅》。
IF 2.2
Trends in Psychiatry and Psychotherapy Pub Date : 2026-01-01 Epub Date: 2024-09-25 DOI: 10.47626/2237-6089-2024-0936
Andreia Biolo, Simone Hauck, Roberto Nunes Umpiere, Santiago Madeira Diefenthaeler, Marina Luiza Hartmann, Rafael Hermes Desimon, Gabriela Hackmann, Gisele Gus Manfro, Lúcia Kliemann
{"title":"Actions and joint efforts of a public school of medicine to promote health and well-being during a climate disaster: a journey toward community resilience.","authors":"Andreia Biolo, Simone Hauck, Roberto Nunes Umpiere, Santiago Madeira Diefenthaeler, Marina Luiza Hartmann, Rafael Hermes Desimon, Gabriela Hackmann, Gisele Gus Manfro, Lúcia Kliemann","doi":"10.47626/2237-6089-2024-0936","DOIUrl":"10.47626/2237-6089-2024-0936","url":null,"abstract":"","PeriodicalId":46305,"journal":{"name":"Trends in Psychiatry and Psychotherapy","volume":" ","pages":"e20240936"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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