AIDS Research and Treatment最新文献_第8页

Socioeconomic Status and Vulnerability to HIV Infection in Uganda: Evidence from Multilevel Modelling of AIDS Indicator Survey Data. 乌干达的社会经济状况和艾滋病毒感染的脆弱性：来自艾滋病指标调查数据的多层次建模的证据。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-06-07 DOI: 10.1155/2018/7812146

Patrick Igulot, Monica A Magadi

{"title":"Socioeconomic Status and Vulnerability to HIV Infection in Uganda: Evidence from Multilevel Modelling of AIDS Indicator Survey Data.","authors":"Patrick Igulot, Monica A Magadi","doi":"10.1155/2018/7812146","DOIUrl":"10.1155/2018/7812146","url":null,"abstract":"Background: There is controversy on the association between socioeconomic status (SES) and HIV infection. Some evidence claims higher SES is negatively associated with HIV infection while others report the reverse.Objectives: To examine the association between SES and HIV infection in Uganda and to examine whether the SES-HIV relationship varies by gender, rural-urban place of residence, and time (2004-2005 and 2011) in Uganda.Methods: Multilevel analysis was applied to 39,766 individual cases obtained in 887 clusters of Uganda HIV/AIDS Indicators Survey conducted in 2004-2005 and 2011.Results: Household wealth is associated with increased vulnerability in the general population and in rural areas. Compared with no educational attainment, secondary or higher education is associated with reduced vulnerability to the risk of HIV infection by 37% in the general population. However, this effect was stronger in urban than rural areas. Besides individual-level factors, unobserved community factors too play an important role and account for 9% of unexplained variance after individual-level factors are considered.Conclusion: Household wealth increases vulnerability but education reduces it. The social environment influences vulnerability to HIV infection independent of individual-level factors. HIV/AIDS awareness targeting sexual practices of wealthy individuals and those with primary-level educational attainment together with improving educational attainment and addressing contextual factors influencing vulnerability to HIV infection are necessary strategies to reduce HIV infections in Uganda.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"7812146"},"PeriodicalIF":1.7,"publicationDate":"2018-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7812146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36293204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Trauma and Growth: Impact of AIDS Activism. 创伤与成长:艾滋病行动主义的影响。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-05-24 eCollection Date: 2018-01-01 DOI: 10.1155/2018/9696725

Judith G Rabkin, Martin C McElhiney, Mark Harrington, Tim Horn

{"title":"Trauma and Growth: Impact of AIDS Activism.","authors":"Judith G Rabkin, Martin C McElhiney, Mark Harrington, Tim Horn","doi":"10.1155/2018/9696725","DOIUrl":"https://doi.org/10.1155/2018/9696725","url":null,"abstract":"Introduction: Our goal was to assess the long-term impact of AIDS activism of ACT UP/New York on the current adjustment of those who were members during its peak years (1987-1992), including assessment of trauma sequelae as well as posttraumatic growth.Methods: A 90-minute semistructured interview and 6 validated self-report scales were administered. We relied on purposive and snowball sampling to recruit potential participants. Areas covered include demographics, ACT UP participation, and psychiatric problems. Self-report scales provided approximate diagnoses of PTSD and depression, as well as coping, optimism, and related concepts.Results: Participants included 102 men (40% HIV-positive) and 23 women. Seventeen percent reported current symptoms suggesting PTSD, slightly above the range in general population studies. Symptoms consistent with depression were reported by 8% overall, with higher rates for HIV+ men. Enhanced sense of self, belief in change, and empowerment were reported by 93% of respondents, independent of concurrent PTSD or depression.Conclusions: Twenty-eight years later, ACT UP study participants recall their activist days during the AIDS epidemic as the peak experience of their lives. While some continue to have symptoms of stress and depression, most found that their activism has enriched their subsequent lives.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"9696725"},"PeriodicalIF":1.7,"publicationDate":"2018-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/9696725","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36300346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Messaging Circumstances and Economic Pressures as Influences on Linkage to Medical Male Circumcision following Community-Based HIV Testing for Men in Rural Southwest Uganda: A Qualitative Study. 信息环境和经济压力对乌干达西南部农村男性社区艾滋病毒检测后医学男性包皮环切的影响:一项定性研究。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-05-03 eCollection Date: 2018-01-01 DOI: 10.1155/2018/8387436

Hannah N Gilbert, Monique A Wyatt, Stephen Asiimwe, Bosco Turyamureeba, Elioda Tumwesigye, Heidi Van Rooyen, Ruanne V Barnabas, Connie L Celum, Norma C Ware

{"title":"Messaging Circumstances and Economic Pressures as Influences on Linkage to Medical Male Circumcision following Community-Based HIV Testing for Men in Rural Southwest Uganda: A Qualitative Study.","authors":"Hannah N Gilbert, Monique A Wyatt, Stephen Asiimwe, Bosco Turyamureeba, Elioda Tumwesigye, Heidi Van Rooyen, Ruanne V Barnabas, Connie L Celum, Norma C Ware","doi":"10.1155/2018/8387436","DOIUrl":"10.1155/2018/8387436","url":null,"abstract":"Voluntary medical male circumcision (MMC) reduces risk of HIV infection, but uptake remains suboptimal among certain age groups and locations in sub-Saharan Africa. We analysed qualitative data as part of the Linkages Study, a randomized controlled trial to evaluate community-based HIV testing and follow-up as interventions promoting linkage to HIV treatment and prevention in Uganda and South Africa. Fifty-two HIV-negative uncircumcised men participated in the qualitative study. They participated in semistructured individual interviews exploring (a) home HTC experience; (b) responses to test results; (c) efforts to access circumcision services; (d) outcomes of efforts; (e) experiences of follow-up support; and (f) local HIV education and support. Interviews were audio-recorded, translated, transcribed, and summarized into \"linkage summaries.\" Summaries were analysed inductively to identify the following three thematic experiences shaping men's circumcision choices: (1) intense relief upon receipt of an unanticipated seronegative diagnosis, (2) the role of peer support in overcoming fear, and (3) anticipation of missed economic productivity. Increased attention to the timing of demand creation activities, to who delivers information about the HIV prevention benefits of MMC, and to the importance of missed income during recovery as a barrier to uptake promises to strengthen and sharpen future MMC demand creation strategies.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"8387436"},"PeriodicalIF":1.7,"publicationDate":"2018-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/8387436","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36182574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Reproduction and Fertility Beliefs, Perceptions, and Attitudes in People Living with HIV. 艾滋病毒感染者的生殖和生育信仰、观念和态度。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-04-01 eCollection Date: 2018-01-01 DOI: 10.1155/2018/5349793

Vaidehi Mujumdar, Doris Berman, Katherine R Schafer

{"title":"Reproduction and Fertility Beliefs, Perceptions, and Attitudes in People Living with HIV.","authors":"Vaidehi Mujumdar, Doris Berman, Katherine R Schafer","doi":"10.1155/2018/5349793","DOIUrl":"https://doi.org/10.1155/2018/5349793","url":null,"abstract":"People living with HIV (PLWH) have distinct needs when it comes to reproductive health, specifically regarding fertility, family planning, and pregnancy, and these needs are often complicated by HIV status. While there is ample research that focuses on reproductive health in PLWH through a quantitative lens, there is a lack of research using qualitative methods, namely, the narrative interview model. We searched PubMed and relevant abstracts to identify 72 articles published from 1997 to 2016 that described a qualitative framework for exploring the behaviors and perceptions regarding family planning, abortion, pregnancy, parenthood, fertility, and forced sterility in PLWH. The inclusion criteria initially showed 147 articles, which were further screened to exclude those that did not address fertility and family planning specifically. Our final sample of articles included articles related to qualitative research on reproductive attitudes, beliefs, and behaviors of PLWH. Several of these articles were mixed-methods analyses, but our focus was on the qualitative portion only. Further qualitative works in this area will not only contribute to gaps quantitative research in the field cannot capture by design, but also inform clinical practice, policy, and interventions through systematic, in-depth evaluation.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"5349793"},"PeriodicalIF":1.7,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5349793","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36136225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

The Impact of Perceived Stigma, Quality of Life, and Spiritual Beliefs on Suicidal Ideations among HIV-Positive Patients. 感知耻辱、生活质量和精神信仰对hiv阳性患者自杀意念的影响。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-03-26 eCollection Date: 2018-01-01 DOI: 10.1155/2018/6120127

Nooshin Zarei, Hassan Joulaei

{"title":"The Impact of Perceived Stigma, Quality of Life, and Spiritual Beliefs on Suicidal Ideations among HIV-Positive Patients.","authors":"Nooshin Zarei, Hassan Joulaei","doi":"10.1155/2018/6120127","DOIUrl":"https://doi.org/10.1155/2018/6120127","url":null,"abstract":"Background: Suicidal ideation is considered a major health problem associated with HIV/AIDS. Suicide rates among people living with HIV/AIDS (PLHA) are more than three times higher in the general population and that is a significant difference. This study aimed at investigating the related factors of suicidal ideations among HIV-positive patients in Southwest Iran.Study design: A cross-sectional study.Methods: 351 adult volunteer HIV-infected patients that referred to the Voluntary Counseling and Testing (VCT) center in the south of Iran were evaluated based on convenience sampling. Data was collected utilizing a structured questionnaire from March to August 2015.Results: Over the six months prior to the study, 15.4% of the entire sample had been diagnosed with suicidal ideation. There was a significant correlation between the quality of life, spiritual beliefs, perceived stigma, and age with suicidal ideation. Suicidal ideation is significantly different in terms of gender and marital status. Perceived stigma and spiritual beliefs showed the highest effect on suicidal ideations, respectively.Conclusions: Having religious beliefs due to accelerating psychological adaptation can motivate HIV patients to survive and have also been considered effective in preventing women from suicide. Perceived stigma and quality of life are other factors that should be taken into consideration as key elements in suicide preventive programs.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"6120127"},"PeriodicalIF":1.7,"publicationDate":"2018-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6120127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36658774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Childhood Adversities and Physical and Mental Health Outcomes in Adults Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study. 成年艾滋病毒感染者的童年逆境和身心健康结局:来自安大略省艾滋病毒治疗网络队列研究的发现

IF 1.7

AIDS Research and Treatment Pub Date : 2018-03-01 eCollection Date: 2018-01-01 DOI: 10.1155/2018/2187232

Tsegaye Bekele, Evan J Collins, Robert G Maunder, Sandra Gardner, Sergio Rueda, Jason Globerman, Thao Lan Le, Jon Hunter, Anita Benoit, Sean B Rourke, The Ohtn Cohort Study Team

{"title":"Childhood Adversities and Physical and Mental Health Outcomes in Adults Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study.","authors":"Tsegaye Bekele, Evan J Collins, Robert G Maunder, Sandra Gardner, Sergio Rueda, Jason Globerman, Thao Lan Le, Jon Hunter, Anita Benoit, Sean B Rourke, The Ohtn Cohort Study Team","doi":"10.1155/2018/2187232","DOIUrl":"https://doi.org/10.1155/2018/2187232","url":null,"abstract":"We sought to estimate the prevalence of childhood adversity and examine its relationship with health outcomes among people living with HIV. Study participants included 1409 adults living with HIV and receiving care in Toronto, Canada. Data on childhood adversity, health behaviors, HIV outcome measures, depression, and health-related quality of life (HRQOL) were collected through face-to-face interviews and medical records. Statistical analyses included multivariable linear and logistic regression modeling. The prevalence of any childhood adversity was 71% (individual types ranged from 11% to 44%) and higher prevalence was associated with younger age, Indigenous or African/Caribbean/Black ethnicity, lower socioeconomic status, and higher rates of cigarette smoking and nonmedicinal drug use. Greater number of childhood adversities was associated with greater odds of depression and decreasing mental HRQOL. HIV care providers need to screen for childhood adversities and address childhood trauma within the context of HIV care.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"2187232"},"PeriodicalIF":1.7,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/2187232","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36036327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Prevalence and Associated Factors of Depression among PLHIV in Ethiopia: Systematic Review and Meta-Analysis, 2017. 埃塞俄比亚 PLHIV 中抑郁症的患病率和相关因素：系统回顾与元分析》，2017年。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-02-28 eCollection Date: 2018-01-01 DOI: 10.1155/2018/5462959

Tadele Amare, Wondale Getinet, Shegaye Shumet, Biksegn Asrat

{"title":"Prevalence and Associated Factors of Depression among PLHIV in Ethiopia: Systematic Review and Meta-Analysis, 2017.","authors":"Tadele Amare, Wondale Getinet, Shegaye Shumet, Biksegn Asrat","doi":"10.1155/2018/5462959","DOIUrl":"10.1155/2018/5462959","url":null,"abstract":"Background: Depression is a substantial contributor to the global burden of disease and affects people in all communities across the globe. Depression is the most common psychiatric problem associated with HIV/AIDS and half of all PLWHIV with depression go underdiagnosed and untreated. Psychiatric complications of HIVAIDS delay mental health services in less affluent countries. However, there is lack of study with regard to the pooled estimation prevalence of depression in PLWHIV in Ethiopia.Objectives: The aim of this systematic review and meta-analysis is to summarize the most current available evidence from 2010 to March 2017 among adult PLWHIV in Ethiopia.Methods: The team explored multiple databases searching methods including MEDLINE/PubMed, PsycINFO, Google Advance Scholar, and Google Scholar to find studies published with the data on the prevalence of depression among PLWHIV. We searched 150 research articles; of these 143 articles were excluded. Subsequently, thirteen articles were used for synthesis prevalence and four studies were included in the synthesis effect of sex on depression among PLWHIV.Results: The total of pooled estimated prevalence of depression in PLWHIV was 36.65. Estimated prevalence of depression in three studies by using CES-D was 31.19% and in six studies by using PHQ-9 was 37.91%. The remaining four studies used a single tool: Kessler-6 Scale (15.5%), HADS (41.2%), HDSQ (43.9%), and BDI (55.8%). Factors such as age, marital status, living alone, poor medication adherence, poor social support, clinical stages II and III of HIV, stigma, income, and occupation were significantly associated with depression.Conclusions and recommendation: The pooled estimate prevalence of depression among PLWHIV was higher than that in the general population. It is better to offer special attention to these populations.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"5462959"},"PeriodicalIF":1.7,"publicationDate":"2018-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36031458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Palatability of Lopinavir and Ritonavir Delivered by an Innovative Freeze-Dried Fast-Dissolving Tablet Formulation. 以创新型冷冻干燥速溶片剂给药的洛匹那韦和利托那韦的适口性

IF 1.7

AIDS Research and Treatment Pub Date : 2018-01-17 eCollection Date: 2018-01-01 DOI: 10.1155/2018/5908167

David W Pittman, Alexandra M Brantly, Alexandra L Drobonick, Hannah T King, Daniel C Mesta, Caroline G Richards, Manjari Lal, Manshun Lai

{"title":"The Palatability of Lopinavir and Ritonavir Delivered by an Innovative Freeze-Dried Fast-Dissolving Tablet Formulation.","authors":"David W Pittman, Alexandra M Brantly, Alexandra L Drobonick, Hannah T King, Daniel C Mesta, Caroline G Richards, Manjari Lal, Manshun Lai","doi":"10.1155/2018/5908167","DOIUrl":"10.1155/2018/5908167","url":null,"abstract":"Negative hedonic sensory qualities of HIV antiretroviral drugs often reduce patient adherence particularly in pediatric populations requiring oral consumption. This study examines the palatability of an innovative delivery mechanism utilizing a freeze-drying-in-blister approach to create fast-dissolving tablets (FDTs) containing a fixed-dose combination of lopinavir and ritonavir (LPV/r). Consumption patterns of solutions during brief-access and long-term testing and baby foodstuff consumption were analyzed to evaluate the orosensory detection and avoidance of placebo FDTs containing no LPV/r (FDT-) and FDTs containing LPV/r (FDT+). Rats showed no change in consumption patterns for the placebo FDT- compared with control solutions. Rats can detect but do not avoid FDT+ at body-weight-adjusted dosages in both brief-access (30-s) and long-term (23 h) consumption tests. There is an aversive response to concentrated doses of FDT+ during brief-access tests that cannot be masked by 25% sucrose. However, the strongest FDT+ concentration was not rejected when mixed with 50 g of applesauce, banana sauce, or rice cereal baby foodstuffs. The averseness of the FDT+ was associated with the presence of LPV/r and not the FDT- formulation itself. The novel FDT formulation appears to be a palatable delivery mechanism for oral antiretroviral pharmaceuticals especially when mixed with baby foodstuffs.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"5908167"},"PeriodicalIF":1.7,"publicationDate":"2018-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35957233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study. HIV感染的鼻腔一氧化氮水平:一项横断面研究。

IF 1.7

AIDS Research and Treatment Pub Date : 2018-01-09 eCollection Date: 2018-01-01 DOI: 10.1155/2018/7645125

Cecilia T Costiniuk, Vikram Mehraj, Jean-Pierre Routy, Christina de Castro, Natale Wasef, Mohammad-Ali Jenabian, Syim Salahuddin, Bertrand Lebouché, Joseph Cox, Jason Szabo, Marina Klein, Larry Lands, Adam J Shapiro

{"title":"Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study.","authors":"Cecilia T Costiniuk, Vikram Mehraj, Jean-Pierre Routy, Christina de Castro, Natale Wasef, Mohammad-Ali Jenabian, Syim Salahuddin, Bertrand Lebouché, Joseph Cox, Jason Szabo, Marina Klein, Larry Lands, Adam J Shapiro","doi":"10.1155/2018/7645125","DOIUrl":"https://doi.org/10.1155/2018/7645125","url":null,"abstract":"Introduction: Low levels of nasal NO have been associated with increased propensity to rhinosinusitis and respiratory tract infections. Our objective was to describe nasal NO levels in HIV-infected individuals versus healthy controls and determine possible risk factors for reduced nasal NO levels.Materials and methods: HIV-infected individuals and healthy controls were recruited. Participants underwent nasal NO testing by standardized methods using a CLD88 chemiluminescence analyzer and completed the Sinonasal Outcome Test-20 (SNOT-20) on symptoms of rhinosinusitis.Results: Participants included 41 HIV-infected individuals with suppressed VL on antiretroviral therapy (ART group), 5 HIV-infected individuals with detectable VL off ART (viremic group), and 12 healthy controls (HC group). Mean nasal NO level was 253 (±77) nL/min in the ART group, 213 (±48) nL/min in the viremic group, and 289 (±68) nL/min in the HC group (p = 0.133; ANOVA). There was no correlation between nasal NO level and VL in viremic individuals (r = -0.200; p = 0.747). Differences were observed in mean total points on the SNOT-20 which were 19 (±16)/100, 18 (±26)/100, and 4 (±4)/100 in the ART, viremic, and HC groups, respectively (p = 0.013; ANOVA).Conclusion: Healthy individuals, HIV patients on ART, and viremic individuals off ART display similar nasal NO levels. However, rhinosinusitis symptoms remain prominent despite ART-treatment.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2018 ","pages":"7645125"},"PeriodicalIF":1.7,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7645125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35926599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Early Diagnosis of HIV among Infants Born to HIV-Positive Mothers on Option-B Plus in Kampala, Uganda. 乌干达坎帕拉艾滋病毒阳性母亲所生婴儿的艾滋病毒早期诊断。

IF 1.7

AIDS Research and Treatment Pub Date : 2017-01-01 Epub Date: 2017-10-19 DOI: 10.1155/2017/4654763

Jonathan Izudi, Sylvia Auma, John Bosco Alege

{"title":"Early Diagnosis of HIV among Infants Born to HIV-Positive Mothers on Option-B Plus in Kampala, Uganda.","authors":"Jonathan Izudi, Sylvia Auma, John Bosco Alege","doi":"10.1155/2017/4654763","DOIUrl":"https://doi.org/10.1155/2017/4654763","url":null,"abstract":"Introduction: Globally, there is delay in accessing early HIV diagnosis (EID) among HIV exposed infants (HEIs). With paucity of data on EID use at Kisenyi Health Center, this study assessed factors associated with EID use among HEIs (HIV exposed infants).Method: This was a cross-sectional study of 246 HIV-positive mother-baby pairs. Data was collected by structured questionnaire, double-entered in EpiData, and analyzed with STATA using multinomial logistic regression at 5% significance level.Results: 132 (53.7%) HEIs were not tested, 60 (24.4%) tested outside EID guideline, and 54 (21.9%) tested per the guideline. Testing per guideline was associated with maternal age above 30 years (AOR = 2.75; 95% CI: 1.20-6.34; P = 0.017); testing outside the guideline was associated with maternal HIV serostatus disclosure (AOR = 2.70; 95% CI: 1.10-6.63; P = 0.003) and four or more antenatal care (ANC) visits (AOR = 3.25; 95% CI: 1.23-8.59; P = 0.017). However, maternal knowledge of HIV transmission was associated with testing outside the guideline (AOR = 2.90; 95% CI: 1.10-7.65; P = 0.032) and per the guideline (AOR = 3.70; 95% CI: 1.39-9.88; P = 0.009).Conclusion: Timely EID testing was low. Improving maternal knowledge of EID during ANC visits and positive living empowerment is critical.","PeriodicalId":46303,"journal":{"name":"AIDS Research and Treatment","volume":"2017 ","pages":"4654763"},"PeriodicalIF":1.7,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/4654763","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35307882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13