Chelsea Miller, Michael J. Shorofsky, Michael Hainstock
{"title":"Transcatheter occlusion of the neoaorta to augment mechanical circulatory support after stage 1 single ventricle palliation","authors":"Chelsea Miller, Michael J. Shorofsky, Michael Hainstock","doi":"10.1016/j.ppedcard.2025.101830","DOIUrl":"10.1016/j.ppedcard.2025.101830","url":null,"abstract":"<div><div>Aortic insufficiency can be a complication of continuous mechanical circulatory support that leads to inefficient circulation and decreased coronary perfusion. In adults, this has been addressed through both surgical and transcatheter approaches. However, this has rarely been reported in children with congenital heart disease. We present the case of a neonate who developed severe neoaortic insufficiency after stage one single ventricle palliation while on central veno-arterial extracorporeal membrane oxygenation (VA-ECMO) that was managed with transcatheter neoaortic occlusion. We used an Amplatzer Vascular Plug II 10 mm device (Abbott Cardiovascular) to successfully improve neoaortic insufficiency and overall hemodynamics. This procedure was technically feasible and may be considered in rare cases to address aortic insufficiency while on mechanical circulatory support.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101830"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hend A. Khalil , Rami A. Sabri , Alaa Abdorahman , Mohamed-Magdy Abuelkheir , Hany M. Abo-Haded
{"title":"Cor triatrium dexter as a rare cause of central cyanosis: A case report","authors":"Hend A. Khalil , Rami A. Sabri , Alaa Abdorahman , Mohamed-Magdy Abuelkheir , Hany M. Abo-Haded","doi":"10.1016/j.ppedcard.2025.101826","DOIUrl":"10.1016/j.ppedcard.2025.101826","url":null,"abstract":"<div><div>Cor triatrium dexter (CTD) is considered a rare congenital heart disease and accounts for 0.1 % of cardiac malformations. This condition occurred due to failure of regression of the right venous valve at the opening of the sinoatrial orifice in the right atrium, dividing the right atrium into 2 parts and forming a tri-atrial heart.</div><div>Case presentation: A 7-year-old child presented with fatigue and exertional dyspnea. Examination revealed oxygen saturation of 85 % and an ejection systolic murmur over the pulmonary area. Echocardiography showed moderate valvular pulmonary stenosis and a suspected membrane in the right atrium, while transesophageal echocardiography revealed a high secundum atrial septal defect (ASD) with bidirectional flow and a non-obstructive membrane in the right atrium, CTD. The patient underwent successful surgical closure of the ASD and resection of the CTD, resulting in improved oxygen saturation (98 %) and significant clinical improvement.</div><div>Conclusion, Cor triatriatum dexter is a rare congenital cardiac anomaly that can be missed on transthoracic echocardiography despite being a potential cause of central cyanosis.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101826"},"PeriodicalIF":0.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143725881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pejman Rohani , Elahe Motamedi , Arian Kariman , Koroush Vahidshahi , Maryam Fathi Khorasani , Mohammad Hassan Sohouli
{"title":"Investigating cardiopulmonary complications in cirrhotic pediatrics with contrast echocardiography","authors":"Pejman Rohani , Elahe Motamedi , Arian Kariman , Koroush Vahidshahi , Maryam Fathi Khorasani , Mohammad Hassan Sohouli","doi":"10.1016/j.ppedcard.2025.101828","DOIUrl":"10.1016/j.ppedcard.2025.101828","url":null,"abstract":"<div><h3>Background</h3><div>Liver cirrhosis is a rare but serious form of liver dysfunction that can lead to severe complications including cardiopulmonary involvement in children.</div></div><div><h3>Objectives</h3><div>In this study, our aim is to investigate the cardiopulmonary complications in children with cirrhosis by using contrast echocardiography.</div></div><div><h3>Method</h3><div>In this observational cross-sectional study, all pediatrics diagnosed with cirrhosis were enrolled from 2020 to 2024. Demographic data, weight, height, BMI, z-score, consanguinity, patient's history, cause of cirrhosis, family history of cirrhosis, laboratory data, abdominal sonography, liver biopsies, and saline contrast echocardiography for arteriovenous malformation (AVM) were evaluated and recorded.</div></div><div><h3>Result</h3><div>A total of twenty-two children were observed, with 59 % of them being boys. The average age of all the children was 8.43 ± 4.6 years. During the study, it was found that 27.3 % of the patients had mild left ventricular diastolic dysfunction, 13.6 % had mild AVM, and 4.5 % had moderate AVM in the contrast echocardiography. No relationship was found between cardiopulmonary complications with age, sex, and laboratory data. However, there was a significant relationship between moderate AVM diagnosed in contrast echocardiography and nodular formation, as well as a significant relationship between left ventricular enlargement (LVE) and nodular formation. One patient had nodular formation in the liver biopsy concurrent with LVE and moderate AVM. Mild AVM was seen in a patient with severe vascular change and giant cell transformation. Additionally, there was a relationship between contrast echocardiography and BUN, creatinine, and vitamin D levels (all <em>P</em>-values <0.05).</div></div><div><h3>Conclusion</h3><div>The results of contrast echocardiography are correlated with some complications of cirrhosis and can be used as a method to evaluate cardiopulmonary complications in children with cirrhosis.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101828"},"PeriodicalIF":0.6,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antoine Fakhry AbdelMassih , Zahraa Allami , Moyasar H. AlTatari , Rahaf Z. AbuGhosh , Alma AlFakhori , Omar J. AlMistarihi , Laila AlKhouli
{"title":"Fontan assist devices; A systematic review of twenty years of experimental and in vivo trials","authors":"Antoine Fakhry AbdelMassih , Zahraa Allami , Moyasar H. AlTatari , Rahaf Z. AbuGhosh , Alma AlFakhori , Omar J. AlMistarihi , Laila AlKhouli","doi":"10.1016/j.ppedcard.2025.101827","DOIUrl":"10.1016/j.ppedcard.2025.101827","url":null,"abstract":"<div><h3>Background</h3><div>The Fontan completion represents the final phase of univentricular repair, which drains the inferior vena cava against gravity into a higher-pressure pulmonary arterial circulation. The passive and anti-gravity characteristics of this circulation make encountering a failing Fontan not uncommon. Twenty years ago, experiments exploring the potential of vascular pumps to bolster the passive Fontan have started, and trials are still ongoing.</div></div><div><h3>Aim of review</h3><div>Through this review, our aim is to summarize the outcomes of these trials.</div></div><div><h3>Key scientific concepts and findings of review</h3><div>A total of ten trials have been included, encompassing 23 different settings. Three distinct designs were identified, of which two are classified as pump designs: the connecting chamber and the intravascular pump designs. Only one trial investigated the potential use of a compression device. The most frequently encountered design in vivo was the intravascular pump, accounting for 67 % of the cases. There were no reports of significant hemolysis or thrombosis. However, an increasing flow rate exceeding 5 L/min was associated with negative outcomes in the connecting chamber design due to rising upstream pressure in the SVC. In contrast, intravascular pumps did not exhibit this limitation.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101827"},"PeriodicalIF":0.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sahar El Shedoudy , Reem Rashed , Asmaa El Fiky , Eman El Doklah
{"title":"Long-term outcomes following patent foramen ovale device closure: A single-center experience","authors":"Sahar El Shedoudy , Reem Rashed , Asmaa El Fiky , Eman El Doklah","doi":"10.1016/j.ppedcard.2025.101824","DOIUrl":"10.1016/j.ppedcard.2025.101824","url":null,"abstract":"<div><h3>Background</h3><div>Patent foramen ovale (PFO) transcatheter closure is recommended for carefully selected patients with cryptogenic stroke and transient ischemic attack (TIA). It has also been associated with significant improvement in the severity of refractory migraine headaches.</div></div><div><h3>Objective</h3><div>To report long-term outcome after PFO closure for patients with stroke, TIA, and refractory migraine.</div></div><div><h3>Methods</h3><div>This retrospective study represents a single-center experience including patients undergoing PFO transcatheter closure for stroke, TIA, or refractory migraine. Patients were followed at 1 and 6 months, one year, and then annually for at least 5 years after closure. After that, patients either attended annually or were followed by telephone interviews. Holter monitoring was done 1–3 months after closure, then selectively according to patient symptoms.</div></div><div><h3>Results</h3><div>We enrolled 480 patients undergoing PFO transcatheter closure between March 2001 and July 2020. 432 patients completed follow-up through August 2024. The follow-up duration ranged from (4–23) years. PFO closure was successful in all patients without complications. New onset atrial fibrillation (AF) occurred in 6 patients (1.39 %), typically later during follow-up (14.0 ± 4.1 years), all with cardiovascular risk factors. Cerebrovascular events recurred 0.31 events/100 person/years. Using the Log-rank test, event recurrence was more observed in patients >40 years in the presence of other cardiovascular risk factors and AF. Regarding Migraine, (82.4 %) of patients experienced complete resolution of symptoms, and (17.6 %) reported mild symptoms (Migraine Disability Assessment Questionnaire (MIDAS) grade I). The mean MIDAS score significantly improved; the mean before closure was 28.3 ± 7.23 and 0.83 ± 1.82 after closure (<em>P</em> = 0.001). The migraine persistence rate was 1.9 events per 100 person-years.</div></div><div><h3>Conclusions</h3><div>Percutaneous PFO closure is a safe and effective long-term intervention for preventing recurrent cerebrovascular events and significantly improves migraine symptoms.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101824"},"PeriodicalIF":0.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Roelle , Maeve M. Sargeant , Nathan Miller , Anthony G. Pompa , William B. Orr , Samuel F. Sears , Jennifer N. Avari Silva
{"title":"Mindfulness based stress reduction program in teenage patients with a cardiac implanted electronic device","authors":"Lisa Roelle , Maeve M. Sargeant , Nathan Miller , Anthony G. Pompa , William B. Orr , Samuel F. Sears , Jennifer N. Avari Silva","doi":"10.1016/j.ppedcard.2025.101821","DOIUrl":"10.1016/j.ppedcard.2025.101821","url":null,"abstract":"<div><h3>Background</h3><div>Increased psychosocial stress and decreased quality of life (QOL) are commonly seen in adolescents with cardiac implanted electronic devices (CIEDs). Mindfulness based stress reduction (MBSR) interventions have been shown to decrease psychosocial stress and improve QOL in cardiovascular patients.</div></div><div><h3>Objective</h3><div>This pilot study assessed the feasibility and effectiveness of an MBSR-teen (MBSR-T) program in adolescents with CIEDs.</div></div><div><h3>Methods</h3><div>Patients aged 14–21 with CIEDs for >1 month enrolled and completed an 8-week MBSR-T course. The program was implemented in two formats: an in-person program for the first cohort of participants and a virtual program for the second cohort. Participants completed pre and post-program surveys: Peds Quality of Life Short Form (PedsQL 4.0 SF), Florida Patient Acceptance Survey (FPAS), and a post-program qualitative survey.</div></div><div><h3>Results</h3><div>Twelve patients (10 with pacemakers, 2 with ICDs, 8 in-person, 4 virtual) completed the course, with a mean age of 16 ± 2 years. Following the intervention, patients reported significantly greater acceptance of their cardiac implantable devices (t(11) = −2.67, <em>p</em> = 0.022). Although not statistically significant, patients reported clinically relevant decreased depression (mean change [MΔ] = −0.75), increased emotional functioning (MΔ = 1.17), and increased social functioning (MΔ = 0.50). Post-program qualitative survey results showed that all participants (100 %) found the program useful and appropriate in both duration and setting, with 9 participants (75 %) recommending it to other teenagers with CIEDs.</div></div><div><h3>Conclusion</h3><div>In-person and virtual MBSR-T programs were feasible and demonstrated decreased device-related distress and improved device acceptance in children with CIEDs.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101821"},"PeriodicalIF":0.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Redefining success in pediatric clinical trials","authors":"Humera Ahmed, Joseph W. Rossano","doi":"10.1016/j.ppedcard.2025.101820","DOIUrl":"10.1016/j.ppedcard.2025.101820","url":null,"abstract":"<div><h3>Background</h3><div>Historically, there have been limited clinical trials in pediatric patients with cardiomyopathy or heart failure. Although the number of these studies has increased in recent years, many have failed to meet their primary endpoints. However, these “negative” trials have been invaluable to the field of pediatric cardiology.</div></div><div><h3>Aim of review</h3><div>This review aims to highlight the importance of negative clinical trials in pediatric cardiology. It focuses on how these trials, despite not meeting their primary objectives, have provided critical insights into safety, drug metabolism, biomarkers, and have contributed to refining trial design for future studies.</div></div><div><h3>Key scientific concepts of review</h3><div>Negative trials have played a key role in advancing pediatric heart failure treatment by revealing essential data on drug metabolism, particularly across different age groups, and by identifying novel biomarkers for monitoring treatment efficacy. These trials have also led to improvements in trial design, ensuring better patient selection and more accurate evaluation of therapeutic interventions. Despite not meeting their primary endpoints, these studies have provided a foundation for future innovations and have helped shape treatment strategies in pediatric cardiology.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101820"},"PeriodicalIF":0.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Ayyaz, Abdul Sattar Shaikh, Salahudin Kakar, Hussain Bux Korejo, Ram Chand, Aliya Kemal Ahsan, Rumana Sangi, Sanam Khan, Veena Kumari
{"title":"Multi center experience with Cocoon Duct Occluder for closure of different types of patent ductus arteriosus (PDA)","authors":"Muhammad Ayyaz, Abdul Sattar Shaikh, Salahudin Kakar, Hussain Bux Korejo, Ram Chand, Aliya Kemal Ahsan, Rumana Sangi, Sanam Khan, Veena Kumari","doi":"10.1016/j.ppedcard.2025.101818","DOIUrl":"10.1016/j.ppedcard.2025.101818","url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter closure of patent ductus arteriosus (PDA) is a widely practiced procedure using various duct occluder devices.</div></div><div><h3>Objective</h3><div>To assess the safety and efficacy of the Cocoon Duct Occluder for PDA closure.</div></div><div><h3>Methods</h3><div>This single-arm cohort study, conducted in the Pediatric Cardiology Departments of NICVD Karachi, TMK, and Sukkur, included both prospective and retrospective recruitment. Using non-probability consecutive sampling, a minimum sample size of 35 was calculated to achieve a 90 % success rate with a 95 % confidence level. A total of 195 patients met the inclusion criteria over 2.5 years. Comprehensive preprocedural assessments were performed, including medical history, clinical examination, electrocardiography, chest X-ray, full blood count, and detailed echocardiographic measurements of PDA dimensions and left ventricular function. Procedures were performed by experienced pediatric cardiologists.</div></div><div><h3>Results</h3><div>PDA closure was successfully achieved in 186 of 195 patients (95.3 %). The most common PDA type was Type A (86.6 %), followed by Type B (4.6 %), Type C (2.6 %), Type D (3 %), and Type E (3 %) per Krichenko's classification. Minor complications included peripheral vascular injury (6.6 %), arterial thrombosis (4 patients), venous thrombosis (7 patients), and arrhythmias (5 patients: 4 with supra-ventricular tachycardia [SVT] and 1 with ventricular tachycardia [VT], of which 2 SVT cases required adenosine therapy). One major complication, i.e. infective endocarditis, and no other major complications, such as device embolization or vascular injury, were observed.</div></div><div><h3>Conclusion</h3><div>The Cocoon Duct Occluder is a safe and effective device for PDA closure across all anatomical types. The procedure's success is enhanced through meticulous device sizing, proper technique, and operator experience, minimizing the risk of major complications.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101818"},"PeriodicalIF":0.6,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anudya Kartika Ratri , I. Gde Rurus Suryawan , Meity Ardiana , Andrianto , Stavros G. Drakos
{"title":"Corrigendum to “Prognostic biomarkers and clinical parameters in adults with atrial septal defect-related pulmonary arterial hypertension treated with sildenafil and beraprost combination therapy” [Prog. Pediadtr. Cardiol. 2024 vol 73 article number PPC_PPC-D-23-00087]","authors":"Anudya Kartika Ratri , I. Gde Rurus Suryawan , Meity Ardiana , Andrianto , Stavros G. Drakos","doi":"10.1016/j.ppedcard.2025.101817","DOIUrl":"10.1016/j.ppedcard.2025.101817","url":null,"abstract":"","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101817"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selma M.A. Ahmed , Eintsar Ali , Sara F.E. Mohammed , Samah A.M. Taha , Wafa M.A. Yousif , Farida A.A. Nimir , Hassan O.A. Mohammed , Abdelmoneim Adam , Mohmmed A. Mohmmed Ahmed , Sulafa K.M. Ali
{"title":"Patterns and outcomes of 975 patients with congenital heart disease from the Sudan Congenital Heart Disease Registry- (Sudan CHEER)","authors":"Selma M.A. Ahmed , Eintsar Ali , Sara F.E. Mohammed , Samah A.M. Taha , Wafa M.A. Yousif , Farida A.A. Nimir , Hassan O.A. Mohammed , Abdelmoneim Adam , Mohmmed A. Mohmmed Ahmed , Sulafa K.M. Ali","doi":"10.1016/j.ppedcard.2025.101814","DOIUrl":"10.1016/j.ppedcard.2025.101814","url":null,"abstract":"<div><h3>Background</h3><div>Congenital heart disease (CHD) constitutes an important cause of mortality and morbidity in children. In limited resource settings, data regarding patterns and outcomes of CHD are deficient.</div></div><div><h3>Objectives</h3><div>To describe the clinical and echocardiographic (echo) features as well as outcomes of patients with CHD seen at Sudan Heart Center.</div></div><div><h3>Methods</h3><div>This is a study reporting results of the <u>Sudan C</u>ongenital <u>He</u>art Dis<u>e</u>ase <u>R</u>egistry (<u>Sudan CHEER</u>) from January 2021–September 2022. Clinical, echo, and interventional management data were collected from hospital records as well as through telephone calls.</div></div><div><h3>Results</h3><div>975 patients with CHD were included (males 53 %). The most common age group was 1–12 months (40 %), and only 7 % were neonates. Acyanotic CHD constituted 71 % of patients. Eisenmenger's syndrome was present in 37 patients (3.8 %). Surgery was indicated in 472 patients (48 %) and performed in 167 (35 % of those in need). The Risk Adjustment Scale for CHD surgery was 2 for 70 % of cases. Interventional cardiac catheterization was indicated in 226 patients and done in 70 % of these. Only 56 % of patients were accessible for follow up period, mean of 12 months. Of unoperated patients, 25 died (6 %), mostly (43 %) having left to right shunts. The surgical operative mortality was 12 %; 80 % of those who underwent surgery did not have residual lesions. Interventional catheterization mortality was 0.6 %, and all survivors were well on follow up. Of those who had palliative interventional procedures, 70 % are still awaiting corrective surgery.</div></div><div><h3>Conclusion</h3><div>There are huge gaps in early diagnosis and access to interventions that need to be addressed to improve outcomes of patients with CHD in Sudan and similarly low-income countries.</div></div>","PeriodicalId":46028,"journal":{"name":"PROGRESS IN PEDIATRIC CARDIOLOGY","volume":"77 ","pages":"Article 101814"},"PeriodicalIF":0.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143465012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}