N Mallofré, G Torres, C Roca, P Rojas, M Sutil, N Casanovas, M Lloreda, F Castaldo, E Bosch, A Martínez-Rubio
{"title":"Oral Presentation Award Winner: LDL-C Reduction in Diabetic Patients after Percutaneous Coronary Intervention: Is There any Difference with Non-diabetic?","authors":"N Mallofré, G Torres, C Roca, P Rojas, M Sutil, N Casanovas, M Lloreda, F Castaldo, E Bosch, A Martínez-Rubio","doi":"10.15420/ecr.2023.18.PO2","DOIUrl":"https://doi.org/10.15420/ecr.2023.18.PO2","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e19"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/2f/ecr-18-e19.PMC10316379.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9793291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to Improve Clinical Outcomes and Reduce Cardiovascular Risk in Older People with Cardiovascular Disease: Bridging Evidence Gaps.","authors":"Mauricio Wajngarten","doi":"10.15420/ecr.2022.59","DOIUrl":"https://doi.org/10.15420/ecr.2022.59","url":null,"abstract":"<p><p>The geriatric population is greatly impacted by cardiovascular disease. Thus, it becomes essential to 'geriatricise' the cardiologist through the dissemination of geriatric cardiology. In the early days of geriatric cardiology, it was discussed whether it was simply cardiology 'well done'. Today, 40 years later, it seems clear that this is indeed the case. Patients with cardiovascular disease usually have several chronic conditions. Clinical practice guidelines often address a single condition and do not provide sufficient guidance for patients with multimorbidity. There are several evidence gaps regarding these patients. Physicians and members ofthe care team need a multidimensional understanding ofthe patient to better promote the optimisation of care. It is important to understand that ageing is inevitable, heterogeneous and increases vulnerability. Caregivers must know how to assess elderly patients in a multidomain practical way and how to recognise the factors that may have implications on treatment.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e17"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/2d/ecr-18-e17.PMC10316345.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9802285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alessandro Cavalcanti Lianza, Maria de Fátima Rodrigues Diniz, Karen Saori Shiraishi Sawamura, Carolina da Rocha Brito Menezes, Isabela de Sousa Lobo Silva, Gabriela Nunes Leal
{"title":"Kawasaki Disease: A Never-ending Story?","authors":"Alessandro Cavalcanti Lianza, Maria de Fátima Rodrigues Diniz, Karen Saori Shiraishi Sawamura, Carolina da Rocha Brito Menezes, Isabela de Sousa Lobo Silva, Gabriela Nunes Leal","doi":"10.15420/ecr.2023.15","DOIUrl":"https://doi.org/10.15420/ecr.2023.15","url":null,"abstract":"<p><p>The most severe complication of Kawasaki disease, an inflammatory disorder of young children, is the formation of coronary artery aneurysms. It is known that patients with coronary artery aneurysms, particularly those with medium and large lesions, have a higher risk of future major cardiovascular events. In contrast, there is a lack of data on the cardiovascular status in long-term follow-up for Kawasaki disease patients without coronary involvement or with self-limited coronary artery aneurysms, resulting in most patients being discharged after 5 years. Even though some paediatricians may believe these patients should not be followed at all, studies indicating a dysfunctional endothelium show the need for further investigation. Consequently, a review of the most significant aspects of Kawasaki disease, and the necessity of correctly identifying, treating and monitoring these patients, particularly those with a higher risk of complications, was conducted.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e47"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/99/ecr-18-e47.PMC10398426.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9954880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time to Integrate Sex in Management of Aortic Valve Stenosis.","authors":"Eva Gerdts, Helga Midtbø","doi":"10.15420/ecr.2022.52","DOIUrl":"https://doi.org/10.15420/ecr.2022.52","url":null,"abstract":"www.ECRjournal.com An increasing body of evidence demonstrates how sex influences the development of degenerative aortic valve stenosis (AS) at the aortic root, the valvular and the left ventricular (LV) levels. While the sex-specific impact of ageing and comorbidities promote differences in remodelling of the aortic root and the LV in AS,1,2 sex differences in tissue biology have been demonstrated in the aortic valve.3 These documented sex differences impact diagnosis, grading, treatment choice and outcome in AS. Still, sex-related differences are not well incorporated into current guidelines for the management of AS.4,5 In this special focus of European Cardiology Review, current evidence for sex differences in AS diagnosis and management is reviewed (Figure 1).6–8","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"18 ","pages":"e05"},"PeriodicalIF":3.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/18/ecr-18-e05.PMC10345976.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10184063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonya Burgess, F Aaysha Cader, Elizabeth Shaw, Shrilla Banerjee, Julia Stehli, Roopa Krishnamorthy, Lynn Khor, Homa Forotan, Alexandra Bastiany, Sarita Rao, Jaya Chandrasekhar, Sarah Zaman, Mirvat Alasnag, Alaide Chieffo, Megan Coylewright
{"title":"Under-representation of Women as Proceduralists and Patients in TAVR and TMVr Procedures: Data, Implications and Proposed Solutions.","authors":"Sonya Burgess, F Aaysha Cader, Elizabeth Shaw, Shrilla Banerjee, Julia Stehli, Roopa Krishnamorthy, Lynn Khor, Homa Forotan, Alexandra Bastiany, Sarita Rao, Jaya Chandrasekhar, Sarah Zaman, Mirvat Alasnag, Alaide Chieffo, Megan Coylewright","doi":"10.15420/ecr.2022.33","DOIUrl":"10.15420/ecr.2022.33","url":null,"abstract":"<p><p>Women are under-represented among transcatheter aortic valve replacement (TAVR) and transcatheter mitral valve repair (TMVr) operators. This review assesses the representation of women as patients and as proceduralists and trial authors in major structural interventions. Women are under-represented as proceduralists in structural interventions: only 2% of TAVR operators and 1% of TMVr operators are women. Only 1.5% of authors in landmark clinical TAVR and TMVr trials are interventional cardiologists who are women (4/260). Significant under-representation and under-enrolment of women in landmark TAVR trials is evident: the calculated participation-to-prevalence ratio (PPR) is 0.73, and in TMVr trials, the PPR is 0.69. Under-representation of women is also evident in registry data (PPR = 0.84 for TAVR registries and for TMVr registries). In structural interventional cardiology, women are under-represented as proceduralists, trial participants and patients. This under-representation has the potential to affect the recruitment of women to randomised trials, subsequent guideline recommendations, selection for treatment, patient outcomes and sex-specific data analysis.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"17 ","pages":"e27"},"PeriodicalIF":3.2,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/eb/1b/ecr-17-e27.PMC9947929.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10799437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of Severe Aortic Valve Stenosis: Impact of Patient Sex and Life Expectancy on Treatment Choice.","authors":"Nina Rashedi, Catherine M Otto","doi":"10.15420/ecr.2022.31","DOIUrl":"10.15420/ecr.2022.31","url":null,"abstract":"<p><p>In adults with severe aortic stenosis, sex and age differences in symptoms and diagnosis may lead to delays in intervention. Choice of intervention partly depends on expected longevity because bioprosthetic valves have limited durability, particularly in younger patients. Current guidelines recommend the following: a mechanical valve in younger adults (aged <50 years) if lifelong anticoagulation is possible and acceptable and a valve-sparing procedure is not possible; surgical mechanical or bioprosthetic aortic valve replacement (SAVR) in adults aged 50-65 years; and transcatheter aortic valve implantation (TAVI) for those aged >80 years based on lower mortality and morbidity compared to SAVR and adequate valve durability. For patients aged 65-80 years, the choice between TAVI and a bioprosthetic SAVR depends on expected longevity, which is greater in women than men, as well as associated cardiac and noncardiac conditions, valvular and vascular anatomy, estimated risk of SAVR versus TAVI and expected complications and patient preferences.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"17 ","pages":"e25"},"PeriodicalIF":3.2,"publicationDate":"2022-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/93/ecr-17-e25.PMC9947935.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10792894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renee P Bullock-Palmer, Katia Bravo-Jaimes, Mamas A Mamas, Cindy L Grines
{"title":"Socioeconomic Factors and their Impact on Access and Use of Coronary and Structural Interventions.","authors":"Renee P Bullock-Palmer, Katia Bravo-Jaimes, Mamas A Mamas, Cindy L Grines","doi":"10.15420/ecr.2022.23","DOIUrl":"10.15420/ecr.2022.23","url":null,"abstract":"<p><p>In the past few decades, the accelerated improvement in technology has allowed the development of new and effective coronary and structural heart disease interventions. There has been inequitable patient access to these advanced therapies and significant disparities have affected patients from low socioeconomic positions. In the US, these disparities mostly affect women, black and hispanic communities who are overrepresented in low socioeconomic. Other adverse social determinants of health influenced by structural racism have also contributed to these disparities. In this article, we review the literature on disparities in access and use of coronary and structural interventions; delineate the possible reasons underlying these disparities; and highlight potential solutions at the government, healthcare system, community and individual levels.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"17 ","pages":"e19"},"PeriodicalIF":3.2,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/eb/d7/ecr-17-e19.PMC9820075.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10533510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"European Society of Cardiology Highlights: Late-breaking Science MINOCA/ANOCA.","authors":"Peter Ong, Andreas Seitz","doi":"10.15420/ecr.2022.22","DOIUrl":"10.15420/ecr.2022.22","url":null,"abstract":"increase without percutaneous coronary intervention. During a mean follow-up of 3.4 ± 3.6 years, 3,321 deaths occurred (18.2%). Compared to patients without MI (16.1%), patients with type 1 MI (25.2%) and type 2 MI (29.1%) had significantly higher mortality rates (p<0.001). Kaplan–Meier analysis confirmed the lowest survival rates occurred in patients with type 2 MI. 2 Moreover, Barrett et al. showed that 1,544 MINOCA patients from Israel had a favourable short-term outcome but their long-term outcome was comparable to that of patients with acute MI due to obstructive coronary artery disease. 3 In addition, in a study including 712 Spanish patients with acute coronary syndrome (ACS), Espinosa Pascual et al. highlighted that pro-inflammatory states such as autoimmune pathologies, connective tissue disease, active cancer and infections should be regarded as risk factors for the occurrence of MINOCA. 4","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"17 ","pages":"e18"},"PeriodicalIF":3.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c3/61/ecr-17-e18.PMC9819995.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10624869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}