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Anticoagulant Therapy for Patients with Coronavirus Disease 2019: Urgent Need for Enhanced Awareness. 2019冠状病毒病患者的抗凝治疗:迫切需要提高认识
IF 3
European Cardiology Review Pub Date : 2020-08-07 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.24
Maki Komiyama, Koji Hasegawa
{"title":"Anticoagulant Therapy for Patients with Coronavirus Disease 2019: Urgent Need for Enhanced Awareness.","authors":"Maki Komiyama,&nbsp;Koji Hasegawa","doi":"10.15420/ecr.2020.24","DOIUrl":"https://doi.org/10.15420/ecr.2020.24","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. SARS-CoV-2 binds to the angiotensin-converting enzyme 2 receptor, which is abundantly expressed in vascular endothelial cells and damages these cells. Besides pneumonia-induced respiratory failure, thrombotic cardiovascular complications are increasingly emerging as a major COVID-19 symptom. Multiple retrospective studies have strongly suggested that anticoagulant therapy improves the prognosis of people with COVID-19. However, validation of the safety and effectiveness of anticoagulant therapy for COVID-19 and greater awareness of this clinical therapeutic option are urgently needed.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e58"},"PeriodicalIF":3.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ea/4c/ecr-15-e58.PMC7479536.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38391649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Coronavirus Disease 2019 and Catheterisation Laboratory Considerations: "Looking for Essentials". 2019冠状病毒病和导管实验室注意事项:“寻找必需品”。
IF 3
European Cardiology Review Pub Date : 2020-07-29 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.29
Syed Haseeb Raza Naqvi, Madiha Fatima, Fady Gerges, Sara Moscatelli, Tugba Kemaloglu Oz, Irina Kotlar, Nigar Babazade, Arash Hashemi, Abdallah Mostafa Almaghraby
{"title":"Coronavirus Disease 2019 and Catheterisation Laboratory Considerations: \"Looking for Essentials\".","authors":"Syed Haseeb Raza Naqvi,&nbsp;Madiha Fatima,&nbsp;Fady Gerges,&nbsp;Sara Moscatelli,&nbsp;Tugba Kemaloglu Oz,&nbsp;Irina Kotlar,&nbsp;Nigar Babazade,&nbsp;Arash Hashemi,&nbsp;Abdallah Mostafa Almaghraby","doi":"10.15420/ecr.2020.29","DOIUrl":"https://doi.org/10.15420/ecr.2020.29","url":null,"abstract":"<p><p>The current coronavirus disease 2019 (COVID-19) outbreak is a significant health crisis that impacts every healthcare system worldwide, and has led to a dramatic change in dealing with different diseases during the pandemic. Interventional cardiologists are frontline workers who deal with many cardiovascular emergencies, either in patients with proven COVID-19 or in suspected cases. Many heart associations worldwide are currently setting appropriate recommendations for the management of emergency cardiac interventions. In this expert opinion, the authors highlight the essential requirements in the cardiac catheterisation laboratory during the COVID-19 pandemic.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e57"},"PeriodicalIF":3.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/50/ecr-15-e57.PMC7463326.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38360948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Response to the Comment 'Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit Coronavirus Disease 2019. 对 "吸烟和血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂戒烟以限制 2019 年冠状病毒疾病 "评论的答复。
IF 3
European Cardiology Review Pub Date : 2020-07-15 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.25
Maki Komiyama, Koji Hasegawa
{"title":"Response to the Comment 'Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit Coronavirus Disease 2019.","authors":"Maki Komiyama, Koji Hasegawa","doi":"10.15420/ecr.2020.25","DOIUrl":"10.15420/ecr.2020.25","url":null,"abstract":"","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e55"},"PeriodicalIF":3.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/7c/ecr-15-e55.PMC7387890.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38218732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Atherosclerotic Cardiovascular Disease Risk with Advanced Lipid Testing: State of the Science. 用高级血脂检测评估动脉粥样硬化性心血管疾病风险：科学现状。
IF 3
European Cardiology Review Pub Date : 2020-07-15 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2019.18
Charles Amir German, Michael David Shapiro
{"title":"Assessing Atherosclerotic Cardiovascular Disease Risk with Advanced Lipid Testing: State of the Science.","authors":"Charles Amir German, Michael David Shapiro","doi":"10.15420/ecr.2019.18","DOIUrl":"10.15420/ecr.2019.18","url":null,"abstract":"<p><p>Cardiovascular disease is the number one cause of death and disability worldwide. While substantial gains have been made in reducing cardiovascular mortality, future projections suggest that we have reached a nadir and may be at an inflection point, given the rising tide of obesity and diabetes. Evaluation and management of plasma lipids is central to the prevention of atherosclerotic cardiovascular disease. Although the standard lipid panel represents a well-established platform to assess risk, this test alone can be insufficient and/or misleading. Advances in our understanding of atherosclerosis have led to the development of lipid-based biomarkers that help to discriminate the risk of cardiovascular disease when it is unclear. While these biomarkers provide novel information, their implementation into clinical medicine remains difficult given discrepancies in the literature, lack of assay standardisation, poor accessibility and high cost. However, additional measures of atherogenic lipoproteins or their surrogates may offer insight beyond the standard lipid panel, providing a more precise assessment of risk and more accurate assessment of lipid-lowering therapy.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e56"},"PeriodicalIF":3.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/47/ecr-15-e56.PMC7387892.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38218733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit Coronavirus Disease 2019. 戒烟和血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂限制2019冠状病毒病
IF 3
European Cardiology Review Pub Date : 2020-07-14 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.20
Marco Rossato, Angelo Di Vincenzo
{"title":"Smoking and Angiotensin-converting Enzyme Inhibitor/Angiotensin Receptor Blocker Cessation to Limit Coronavirus Disease 2019.","authors":"Marco Rossato,&nbsp;Angelo Di Vincenzo","doi":"10.15420/ecr.2020.20","DOIUrl":"https://doi.org/10.15420/ecr.2020.20","url":null,"abstract":"We read with interest the paper by Komiyama and Hasegawa on the need for smoking cessation as a public health measure to limit the coronavirus disease 2019 (COVID-19) pandemic. It seems obvious to reiterate that smoking cessation is advisable to reduce many other severe conditions, such as chronic lung and cardiovascular diseases and some types of cancer, which are leading causes of morbidity and mortality. Cigarette smoking kills more than 8 million people each year worldwide, with more than 7 million of those deaths being the result of direct tobacco use and around 1 million occurring in non-smokers exposed to second-hand smoke.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e54"},"PeriodicalIF":3.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/a7/ecr-15-e54.PMC7387891.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38218731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Using Pharmacogenetic Testing to Tailor Warfarin Therapy: The Singapore Experience and What the Future Holds. 使用药物遗传学测试来定制华法林治疗:新加坡的经验和未来。
IF 3
European Cardiology Review Pub Date : 2020-06-29 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2019.12
Grace Shu-Wen Chang, Doreen Su-Yin Tan
{"title":"Using Pharmacogenetic Testing to Tailor Warfarin Therapy: The Singapore Experience and What the Future Holds.","authors":"Grace Shu-Wen Chang,&nbsp;Doreen Su-Yin Tan","doi":"10.15420/ecr.2019.12","DOIUrl":"https://doi.org/10.15420/ecr.2019.12","url":null,"abstract":"<p><p>Genetic polymorphisms significantly affect individual responses to warfarin, contributing to unpredictability and challenges in managing anticoagulation. Although numerous studies have demonstrated that pharmacogenetic testing improves anticoagulation-related outcomes in the Caucasian population, its effect in the Asian population has not been well studied. This article discusses controversies surrounding tailoring warfarin therapy using pharmacogenetic testing and its role in clinical practice, with a focus on the Asian context. Using the Singapore experience as an example, the authors propose how pharmacogenetic testing can be a means to reduce dose titrations in select patient populations, and how it may be positioned as an enabler to reduce healthcare resources needed for anticoagulation management.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e53"},"PeriodicalIF":3.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/77/ecr-15-e53.PMC7362335.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38169286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Myocardial and Microvascular Injury Due to Coronavirus Disease 2019. 2019冠状病毒病致心肌和微血管损伤
IF 3
European Cardiology Review Pub Date : 2020-06-23 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.22
Rocco A Montone, Giulia Iannaccone, Maria Chiara Meucci, Filippo Gurgoglione, Giampaolo Niccoli
{"title":"Myocardial and Microvascular Injury Due to Coronavirus Disease 2019.","authors":"Rocco A Montone,&nbsp;Giulia Iannaccone,&nbsp;Maria Chiara Meucci,&nbsp;Filippo Gurgoglione,&nbsp;Giampaolo Niccoli","doi":"10.15420/ecr.2020.22","DOIUrl":"https://doi.org/10.15420/ecr.2020.22","url":null,"abstract":"<p><p>Over the past few months, health systems worldwide have been put to the test with the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though the leading clinical manifestations of the SARS-CoV-2 infection involve the respiratory tract, there is a non-negligible risk of systemic involvement leading to the onset of multi-organ failure with fatal consequences. Since the onset of COVID-19, patients with underlying cardiovascular disease have been at increased risk of poor clinical outcomes with higher death rates. Moreover, the occurrence of new-onset cardiac complications is not uncommon among patients hospitalised for COVID-19. Of importance, a significant portion of COVID-19 patients present with myocardial injury. Herein, the authors discuss the mechanisms leading to myocardial and microvascular injury in SARS-CoV-2 infection and their clinical implications.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e52"},"PeriodicalIF":3.0,"publicationDate":"2020-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/43/ecr-15-e52.PMC7325215.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38112065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 33
Coronavirus Disease 2019 Myocarditis: Insights into Pathophysiology and Management. 2019冠状病毒病心肌炎:病理生理学和管理的见解。
IF 3
European Cardiology Review Pub Date : 2020-06-17 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.16
Mahmoud Abdelnabi, Nouran Eshak, Yehia Saleh, Abdallah Almaghraby
{"title":"Coronavirus Disease 2019 Myocarditis: Insights into Pathophysiology and Management.","authors":"Mahmoud Abdelnabi,&nbsp;Nouran Eshak,&nbsp;Yehia Saleh,&nbsp;Abdallah Almaghraby","doi":"10.15420/ecr.2020.16","DOIUrl":"https://doi.org/10.15420/ecr.2020.16","url":null,"abstract":"<p><p>The world is dealing with a global pandemic of severe acute respiratory coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19), which is the illness caused by SARS-CoV-2, is overwhelming healthcare systems around the world. Although the main clinical manifestations of COVID-19 are respiratory symptoms, several reports have noted myocarditis, cardiomyopathy, arrhythmias and cardiac arrests as COVID-19 complications. Here, the authors highlight the current understanding of the pathophysiology of myocarditis related to COVID-19 and its management.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e51"},"PeriodicalIF":3.0,"publicationDate":"2020-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/37/ecr-15-e51.PMC7325211.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38112064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Contemporary Cardiac MRI in Chronic Coronary Artery Disease. 慢性冠状动脉疾病中的当代心脏磁共振成像。
IF 3.2
European Cardiology Review Pub Date : 2020-06-15 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2019.17
Michalis Kolentinis, Melanie Le, Eike Nagel, Valentina O Puntmann
{"title":"Contemporary Cardiac MRI in Chronic Coronary Artery Disease.","authors":"Michalis Kolentinis, Melanie Le, Eike Nagel, Valentina O Puntmann","doi":"10.15420/ecr.2019.17","DOIUrl":"10.15420/ecr.2019.17","url":null,"abstract":"<p><p>Chronic coronary artery disease remains an unconquered clinical problem, affecting an increasing number of people worldwide. Despite the improved understanding of the disease development, the implementation of the many advances in diagnosis and therapy is lacking. Many clinicians continue to rely on patient's symptoms and diagnostic methods, which do not enable optimal clinical decisions. For example, echocardiography and invasive coronary catheterisation remain the mainstay investigations for stable angina patients in many places, despite the evidence on their limitations and availability of better diagnostic options. Cardiac MRI is a powerful diagnostic method, supporting robust measurements of crucial markers of cardiac structure and function, myocardial perfusion and scar, as well as providing detailed insight into myocardial tissue. Accurate and informative diagnostic readouts can help with guiding therapy, monitoring disease progress and tailoring the response to treatment. In this article, the authors outline the evidence supporting the state-of-art applications based on cardiovascular magnetic resonance, allowing the clinician optimal use of this insightful diagnostic method in everyday clinical practice.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e50"},"PeriodicalIF":3.2,"publicationDate":"2020-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/01/ecr-15-e50.PMC7312615.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38107990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early? 2019冠状病毒病患者扩张性心肌病的风险:如何早期识别和表征?
IF 3
European Cardiology Review Pub Date : 2020-05-27 eCollection Date: 2020-02-01 DOI: 10.15420/ecr.2020.17
Maki Komiyama, Koji Hasegawa, Akira Matsumori
{"title":"Dilated Cardiomyopathy Risk in Patients with Coronavirus Disease 2019: How to Identify and Characterise it Early?","authors":"Maki Komiyama,&nbsp;Koji Hasegawa,&nbsp;Akira Matsumori","doi":"10.15420/ecr.2020.17","DOIUrl":"https://doi.org/10.15420/ecr.2020.17","url":null,"abstract":"<p><p>Multiple lines of evidence have shown that elevated blood troponin is strongly associated with poor prognosis in patients with the novel coronavirus disease 2019 (COVID-19). Possible mechanisms of myocardial injury in COVID-19 include ischaemia due to circulatory and respiratory failure, epicardial or intramyocardial small coronary artery thrombotic obstruction due to increased coagulability, and myocarditis caused by systemic inflammation or direct binding of the virus to its receptor, angiotensin-converting enzyme-2 (ACE2), which is abundantly expressed in the heart. It is postulated that persistent immune activation upon viral infection increases the risk of developing dilated cardiomyopathy in COVID-19 patients.</p>","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":"15 ","pages":"e49"},"PeriodicalIF":3.0,"publicationDate":"2020-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/53/ecr-15-e49.PMC7277785.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38042834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
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