European Cardiology Review最新文献

Cardiovascular Drug Interactions with Nirmatrelvir/Ritonavir for COVID-19: Considerations for Daily Practice 用于 COVID-19 的 Nirmatrelvir/Ritonavir 与心血管药物的相互作用：日常实践中的注意事项

IF 3.2

European Cardiology Review Pub Date : 2024-08-09 DOI: 10.15420/ecr.2024.04

Andrea Di Lenarda, Nicola Ferri, Massimiliano Lanzafame, E. Montuori, Luciano Pacelli

{"title":"Cardiovascular Drug Interactions with Nirmatrelvir/Ritonavir for COVID-19: Considerations for Daily Practice","authors":"Andrea Di Lenarda, Nicola Ferri, Massimiliano Lanzafame, E. Montuori, Luciano Pacelli","doi":"10.15420/ecr.2024.04","DOIUrl":"https://doi.org/10.15420/ecr.2024.04","url":null,"abstract":"Cardiovascular disease is associated with progression to severe COVID-19 and patients with the condition are among those in whom early antiviral therapy should be warranted. The combination of nirmatrelvir/ritonavir (Paxlovid®) has been approved for clinical use by the Food and Drug Administration and European Medicines Agency. Because patients with cardiovascular disease are often on polypharmacy, physicians need to be aware of potential drug–drug interactions (DDIs) when treating COVID-19 with nirmatrelvir/ritonavir. Guidance is given for avoiding DDIs, emphasising that preventing and managing potential DDIs with nirmatrelvir/ritonavir requires thorough assessment and knowledge. The present review summarises the clinical pharmacology of nirmatrelvir/ritonavir and provides details on potential DDIs with a focus on daily practice in patients with cardiovascular disease. Particular attention is needed for drugs that are predominantly metabolised by cytochrome P450 3A4, are substrates of P-glycoprotein and have a narrow therapeutic index. Proper management of potential DDIs must balance the benefit of nirmatrelvir/ritonavir to prevent severe disease with the risk of serious adverse events.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Actual Condition of Transthyretin Amyloid Cardiac Amyloidosis: Single Centre Experience 转甲状腺素淀粉样变性心脏淀粉样变性的实际情况：单中心经验

IF 3.2

European Cardiology Review Pub Date : 2024-07-26 DOI: 10.15420/ecr.2024.19.po3

Shunsuke Kiuchi, Shinji Hisatake, Yoshiki Murakami, Takanori Ikeda

引用次数: 0

The Impact on Efficacy and Safety of Patients Receiving Oral Anticoagulant Medication (Warfarin) during the COVID-19 Pandemic 在 COVID-19 大流行期间接受口服抗凝药物（华法林）治疗的患者的疗效和安全性受到的影响

IF 3.2

European Cardiology Review Pub Date : 2024-07-26 DOI: 10.15420/ecr.2024.19.po2

Ubonwan Sapoo, Nuengruthai Phunpha, Patipan Pusopa, Bancha Sookananchai, Chanthaporn Imbumroong, Nilobol Chuemsanthia, Kitiya Muangyot

引用次数: 0

The Effects of Co-injecting Human iPSC-Derived Cardiomyocytes/Pre-epicardial Cells into Cryoinjured Rat Hearts 将人类 iPSC 衍生的心肌细胞/前心肌细胞联合注入冷冻损伤大鼠心脏的影响

IF 3.2

European Cardiology Review Pub Date : 2024-07-26 DOI: 10.15420/ecr.2024.19.po5

Fatin Fazrina Roslan, Yuexin Yu, Nurul Ain Nasim Mohd Yusof, Nor Azlina Khalil, Zhikun Guo, Jer Ping Ooi, Jun Jie Tan

引用次数: 0

Assessment of Direct Oral Anticoagulant Use and Clinical Outcomes among Patients with Renal Impairment at Faculty of Medicine Siriraj Hospital, Mahidol University 评估玛希隆大学医学院 Siriraj 医院肾功能受损患者直接口服抗凝剂的使用情况和临床结果

IF 3.2

European Cardiology Review Pub Date : 2024-07-26 DOI: 10.15420/ecr.2024.19.po1

Apisara Lohachatinante, Nuttanun Kittikunkanyakit, S. Sukkha, S. Chumnumwat, Rattana Chawanasuntharapot, Junporn Kongwatcharapong

引用次数: 0

The Impact of Renin–Angiotensin System Inhibitor Use on Clinical Outcomes by GRACE Score in ST-elevation MI Patients Undergoing Successful Percutaneous Coronary Intervention with Drug-eluting Stents 在成功接受药物洗脱支架经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死患者中，根据 GRACE 评分使用肾素-血管紧张素系统抑制剂对临床结果的影响

IF 3.2

European Cardiology Review Pub Date : 2024-07-26 DOI: 10.15420/ecr.2024.19.po4

Byoung Geo Choi, S. Rha, Se Yeon Choi, J. Cha, S. Hyun, W. Ahn, Soohyung Park, Cheol Ung Choi, Myung Ho Jeong

引用次数: 0

Clinical Management of Non-alcoholic Steatohepatitis and the Role of the Cardiologist 非酒精性脂肪性肝炎的临床治疗与心脏病专家的作用

IF 3

European Cardiology Review Pub Date : 2023-12-22 DOI: 10.15420/ecr.2023.22

Carlos Millán-Rodríguez, Carlos Palacios Castelló Palacios Castelló, M. Caballero-Valderrama, Gonzalo Barón Esquivias

{"title":"Clinical Management of Non-alcoholic Steatohepatitis and the Role of the Cardiologist","authors":"Carlos Millán-Rodríguez, Carlos Palacios Castelló Palacios Castelló, M. Caballero-Valderrama, Gonzalo Barón Esquivias","doi":"10.15420/ecr.2023.22","DOIUrl":"https://doi.org/10.15420/ecr.2023.22","url":null,"abstract":"Non-alcoholic fatty liver disease (NAFLD) is a spectrum of fat-associated liver conditions that increase risk of cardiovascular disease and mortality. The diagnosis and clinical management of NAFLD remain a challenge for cardiologists. Our group performed a systematic review in PubMed of the relationship between NAFLD and cardiovascular disease, identifying 35 relevant articles. NAFLD is likely to be the liver’s expression of metabolic syndrome and increases the risk of several cardiovascular diseases, including coronary artery disease, stroke, heart failure and electrical disorders, and chronic kidney disease. Echocardiography is a useful tool to check early subclinical abnormalities in heart structure and function linked to NAFLD progression, such as cardiac diastolic impairment or epicardial fat thickness. Currently, NAFLD is predominantly managed by lifestyle changes with the aim of weight loss, based on the Mediterranean diet and intense exercise training. Despite the lack of approved drugs for NAFLD, new potential treatments, mainly glucagon-like peptide-1 agonists or sodium–glucose cotransporter 2 inhibitors, could change cardiologists’ approach to this pathology.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138944741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-based Management of Left Main Coronary Artery Disease 左冠状动脉主干疾病的循证管理

IF 3

European Cardiology Review Pub Date : 2023-12-19 DOI: 10.15420/ecr.2023.36

G. Torres-Ruiz, Nuria Mallofré-Vila, P. Rojas-Flores, Pablo Carrión-Montaner, E. Bosch-Peligero, Daniel Valcárcel-Paz, Ada Cardiel-Perez, J. Guindo-Soldevila, Antonio Martínez-Rubio

{"title":"Evidence-based Management of Left Main Coronary Artery Disease","authors":"G. Torres-Ruiz, Nuria Mallofré-Vila, P. Rojas-Flores, Pablo Carrión-Montaner, E. Bosch-Peligero, Daniel Valcárcel-Paz, Ada Cardiel-Perez, J. Guindo-Soldevila, Antonio Martínez-Rubio","doi":"10.15420/ecr.2023.36","DOIUrl":"https://doi.org/10.15420/ecr.2023.36","url":null,"abstract":"Left main coronary artery disease (LMCAD) is associated with high morbidity and mortality due to the large myocardial mass at risk. Although medical treatment may be an option in selected low-risk patients, revascularisation is recommended to improve survival in the majority of patients presenting with a significant left main stenosis. In the past decade, multiple randomised clinical trials and meta-analyses have compared coronary artery bypass grafting surgery (CABG) versus percutaneous coronary intervention (PCI), finding controversial results. The strategy for LMCAD revascularisation is still challenging. Coronary anatomy complexity, clinical features and patient preferences are key elements to be considered by the heart team. The current guidelines define CABG as standard therapy, but the continuous improvements in PCI techniques, the use of intracoronary imaging and functional assessment make PCI a feasible alternative in selected patients, particularly in those with comorbidities and contraindications to CABG. This review analyses the most important studies comparing CABG versus PCI in patients with LMCAD.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138961117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2 根据患者情况选择非维生素 K 拮抗剂口服抗凝药预防心房颤动患者中风：越南专家的观点。第二部分

IF 3

European Cardiology Review Pub Date : 2023-12-15 DOI: 10.15420/ecr.2023.25

Minh That Ton, T. H. Q. Ho, Viet Lan Nguyen, Hung Manh Pham, S. Hoang, Nhan Thanh Vo, Thai Quoc Nguyen, Linh Tran Pham, Ton Duy Mai, Thang Huy Nguyen

{"title":"Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 2","authors":"Minh That Ton, T. H. Q. Ho, Viet Lan Nguyen, Hung Manh Pham, S. Hoang, Nhan Thanh Vo, Thai Quoc Nguyen, Linh Tran Pham, Ton Duy Mai, Thang Huy Nguyen","doi":"10.15420/ecr.2023.25","DOIUrl":"https://doi.org/10.15420/ecr.2023.25","url":null,"abstract":"Part 1 of this review provided an overview of AF in Vietnam, with a particular focus on primary and secondary stroke prevention. Part 2 explores the management of AF in special, high-risk and clinically common patient populations including those with renal impairment, diabetes, the elderly, and those with coronary artery disease. Furthermore, Part 2 addresses the challenges posed by patients with AF who have a bioprosthetic valve, a group situated in a grey area of consideration. Managing AF in these patient groups presents unique clinical challenges that require careful consideration. Physicians are tasked with addressing specific clinical questions to identify the optimal anticoagulation strategy for each individual. To inform these decisions, subgroup analyses from pivotal studies are presented alongside real-world data derived from clinical practice. By synthesising available information and considering the nuanced clinical context, the aim is to provide informed perspectives that align with current medical knowledge and contribute to the enhancement of patient care in these challenging scenarios.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 1 根据患者情况选择非维生素 K 拮抗剂口服抗凝药预防心房颤动患者中风：越南专家的观点。第一部分

IF 3

European Cardiology Review Pub Date : 2023-12-15 DOI: 10.15420/ecr.2023.24

T. H. Q. Ho, Minh That Ton, Viet Lan Nguyen, Hung Manh Pham, S. Hoang, Nhan Thanh Vo, Thai Quoc Nguyen, Linh Tran Pham, Ton Duy Mai, Thang Huy Nguyen

{"title":"Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 1","authors":"T. H. Q. Ho, Minh That Ton, Viet Lan Nguyen, Hung Manh Pham, S. Hoang, Nhan Thanh Vo, Thai Quoc Nguyen, Linh Tran Pham, Ton Duy Mai, Thang Huy Nguyen","doi":"10.15420/ecr.2023.24","DOIUrl":"https://doi.org/10.15420/ecr.2023.24","url":null,"abstract":"In Asia, especially Vietnam, AF is a common arrhythmia and is linked to a higher risk of stroke and systemic embolism. Anticoagulation therapy for stroke prevention in AF patients can result in bleeding complications. To effectively manage AF, adopting appropriate anticoagulation and addressing modifiable risk factors are crucial. Vietnamese clinicians are particularly interested in non-vitamin K antagonist oral anticoagulants (NOACs), a recent development in AF treatment. However, the lack of head-to-head trials comparing NOACs makes selecting a specific NOAC challenging. This review aims to provide a comprehensive overview of the available clinical evidence on NOACs for stroke prevention in AF to assist clinicians in making informed decisions and improving treatment outcomes in patients with AF. The first part of this review will present the current landscape of AF in Vietnam, focusing on AF prevalence and highlighting gaps in clinical practice. Furthermore, this part extensively discusses the anticoagulation strategy for both primary and secondary stroke prevention in AF.","PeriodicalId":45957,"journal":{"name":"European Cardiology Review","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0