Under-representation of Women as Proceduralists and Patients in TAVR and TMVr Procedures: Data, Implications and Proposed Solutions.

IF 3.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
European Cardiology Review Pub Date : 2022-12-19 eCollection Date: 2022-02-01 DOI:10.15420/ecr.2022.33
Sonya Burgess, F Aaysha Cader, Elizabeth Shaw, Shrilla Banerjee, Julia Stehli, Roopa Krishnamorthy, Lynn Khor, Homa Forotan, Alexandra Bastiany, Sarita Rao, Jaya Chandrasekhar, Sarah Zaman, Mirvat Alasnag, Alaide Chieffo, Megan Coylewright
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引用次数: 0

Abstract

Women are under-represented among transcatheter aortic valve replacement (TAVR) and transcatheter mitral valve repair (TMVr) operators. This review assesses the representation of women as patients and as proceduralists and trial authors in major structural interventions. Women are under-represented as proceduralists in structural interventions: only 2% of TAVR operators and 1% of TMVr operators are women. Only 1.5% of authors in landmark clinical TAVR and TMVr trials are interventional cardiologists who are women (4/260). Significant under-representation and under-enrolment of women in landmark TAVR trials is evident: the calculated participation-to-prevalence ratio (PPR) is 0.73, and in TMVr trials, the PPR is 0.69. Under-representation of women is also evident in registry data (PPR = 0.84 for TAVR registries and for TMVr registries). In structural interventional cardiology, women are under-represented as proceduralists, trial participants and patients. This under-representation has the potential to affect the recruitment of women to randomised trials, subsequent guideline recommendations, selection for treatment, patient outcomes and sex-specific data analysis.

Abstract Image

在 TAVR 和 TMVr 手术中,女性手术者和患者的比例偏低:数据、影响和建议的解决方案。
在经导管主动脉瓣置换术(TAVR)和经导管二尖瓣修复术(TMVr)的操作者中,女性的比例偏低。本综述评估了在主要结构性介入治疗中女性作为患者、程序师和试验作者的代表性。在结构性介入治疗中,女性手术医师的比例偏低:TAVR 手术医师中仅有 2%,TMVr 手术医师中仅有 1%。在具有里程碑意义的 TAVR 和 TMVr 临床试验中,只有 1.5% 的作者是女性介入心脏病专家(4/260)。在具有里程碑意义的 TAVR 试验中,女性的代表性和参与率明显不足:计算得出的参与率与患病率之比(PPR)为 0.73,而在 TMVr 试验中,PPR 为 0.69。在登记数据中,女性代表不足的情况也很明显(TAVR 登记和 TMVr 登记的 PPR = 0.84)。在结构性介入心脏病学领域,女性作为手术医师、试验参与者和患者的比例偏低。这种代表性不足可能会影响随机试验对女性的招募、随后的指南推荐、治疗选择、患者预后和性别特异性数据分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
European Cardiology Review
European Cardiology Review CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
5.40
自引率
0.00%
发文量
23
审稿时长
12 weeks
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