Tzu Chi Medical Journal最新文献

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Percutaneous endoscopic lumbar discectomy versus open lumbar microdiscectomy for treating lumbar disc herniation: Using the survival analysis. 经皮内镜下腰椎间盘切除术与开放式显微腰椎间盘切除术治疗腰椎间盘突出症:使用生存分析。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-07-01 DOI: 10.4103/tcmj.tcmj_262_22
Chang-Hao Lin, Yi-Hung Huang, Fang-Chieh Lien, Cheng-Yi Wu, Lin-Yu Chao
{"title":"Percutaneous endoscopic lumbar discectomy versus open lumbar microdiscectomy for treating lumbar disc herniation: Using the survival analysis.","authors":"Chang-Hao Lin,&nbsp;Yi-Hung Huang,&nbsp;Fang-Chieh Lien,&nbsp;Cheng-Yi Wu,&nbsp;Lin-Yu Chao","doi":"10.4103/tcmj.tcmj_262_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_262_22","url":null,"abstract":"<p><strong>Objectives: </strong>This study compared the risk of symptomatic recurrent disc herniation and clinical outcomes of percutaneous endoscopic lumbar discectomy (PELD) versus open lumbar microdiscectomy (OLM) for lumbar disc herniation with 2 years of follow-up.</p><p><strong>Materials and methods: </strong>We analyzed 23 patients who underwent PELD and 32 patients who underwent OLM for lumbar disc herniation. The numeric rating scale of back and leg pain, Oswestry Disability Index (ODI), and Roland-Morris Disability Questionnaire (RMDQ) were assessed before and at 12 and 24 months after the surgery. The wound pain and complications were also recorded. Survival analysis was performed to estimate the risk of symptomatic recurrent disc herniation.</p><p><strong>Results: </strong>In the comparison of groups, the reductions in back and leg pain, ODI, and RMDQ were not significantly different at 12 and 24 months. For patients who underwent PELD, the wound pain was significant lower at the day of surgery. The survival rate of patients who were free from symptomatic recurrent disc herniation at 24 months was 0.913 in PELD and 0.875 in OLM, and the log-rank test revealed no significant difference between the two survival curves. The incidence of complication was not significantly different between groups.</p><p><strong>Conclusion: </strong>Both PELD and OLM are effective treatments for lumbar disc herniation because they have similar clinical outcomes. PELD provided patients with less painful wounds. The survival analysis revealed that the risk of symptomatic recurrent disc herniation in 2 years of follow-up was not different between PELD and OLM.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"237-241"},"PeriodicalIF":1.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/04/TCMJ-35-237.PMC10399846.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronavirus disease 2019 and cardiovascular disease. 2019冠状病毒病和心血管疾病。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-07-01 DOI: 10.4103/tcmj.tcmj_219_22
Jenn-Yeu Song, Jian-You Huang, Yi-Chiung Hsu, Men-Tzung Lo, Chen Lin, Ta-Chung Shen, Min-Tser Liao, Kuo-Cheng Lu
{"title":"Coronavirus disease 2019 and cardiovascular disease.","authors":"Jenn-Yeu Song,&nbsp;Jian-You Huang,&nbsp;Yi-Chiung Hsu,&nbsp;Men-Tzung Lo,&nbsp;Chen Lin,&nbsp;Ta-Chung Shen,&nbsp;Min-Tser Liao,&nbsp;Kuo-Cheng Lu","doi":"10.4103/tcmj.tcmj_219_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_219_22","url":null,"abstract":"<p><p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus behind the coronavirus disease 2019 (COVID-19) pandemic, is a type of RNA virus that is nonsegmented. Cardiovascular diseases (CVDs) increase the mortality risk of patients. In this review article, we overview the existing evidence regarding the potential mechanisms of myocardial damage in coronavirus disease 2019 (COVID-19) patients. Having a comprehensive knowledge of the cardiovascular damage caused by SARS-CoV-2 and its underlying mechanisms is essential for providing prompt and efficient treatment, ultimately leading to a reduction in mortality rates. Severe COVID-19 causes acute respiratory distress syndrome and shock in patients. In addition, awareness regarding COVID-19 cardiovascular manifestations has increased, including the adverse impact on prognosis with cardiovascular involvement. Angiotensin-converting enzyme 2 receptor may play a role in acute myocardial injury caused by SARS-CoV-2 infection. COVID-19 patients experiencing heart failure may have their condition exacerbated by various contributing factors and mechanisms. Increased oxygen demand, myocarditis, stress cardiomyopathy, elevated pulmonary pressures, and venous thrombosis are potential health issues. The combination of these factors may lead to COVID-19-related cardiogenic shock, resulting in acute systolic heart failure. Extracorporeal membrane oxygenation (ECMO) and left ventricular assist devices (LVADs) are treatment options when inotropic support fails for effective circulatory support. To ensure effective COVID-19-related cardiovascular disease (CVD) surveillance, it is crucial to closely monitor the future host adaptation, viral evolution, and transmissibility of SARS-CoV-2, given the virus's pandemic potential.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"213-220"},"PeriodicalIF":1.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/8c/TCMJ-35-213.PMC10399840.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10323913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Previous nonhepatectomy abdominal surgery did not increase the difficulty in laparoscopic hepatectomy for hepatocellular carcinoma: A case-control study in 100 consecutive patients. 既往非肝切除腹部手术并未增加肝细胞癌腹腔镜肝切除术的难度:一项连续100例患者的病例对照研究。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-07-01 DOI: 10.4103/tcmj.tcmj_293_22
Yi-Hsuan Lee, Hsiu-Hsien Lin, Tsai-Ling Kuo, Ming-Che Lee, Yen-Cheng Chen
{"title":"Previous nonhepatectomy abdominal surgery did not increase the difficulty in laparoscopic hepatectomy for hepatocellular carcinoma: A case-control study in 100 consecutive patients.","authors":"Yi-Hsuan Lee,&nbsp;Hsiu-Hsien Lin,&nbsp;Tsai-Ling Kuo,&nbsp;Ming-Che Lee,&nbsp;Yen-Cheng Chen","doi":"10.4103/tcmj.tcmj_293_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_293_22","url":null,"abstract":"<p><strong>Objectives: </strong>Laparoscopic hepatectomy (LH) is still technically challenging for patients with previous nonhepatectomy abdominal surgery (AS). Therefore, this study aimed to assess the difficulty of performing LH for patients with hepatocellular carcinoma (HCC) and a history of nonhepatectomy AS during the initial developing period of LH.</p><p><strong>Materials and methods: </strong>The retrospective study enrolled patients who were newly diagnosed with HCC receiving LH from January 2013 to June 2021. Demographic characteristics, perioperative variables, and surgical complications were prospectively collected.</p><p><strong>Results: </strong>One hundred patients were reviewed consecutively, comprising 23 in the AS group and 77 in the non-AS group. No significant differences were observed in median IWATE score (5 vs. 5, <i>P</i> = 0.194), operative time (219 vs. 200 min, <i>P</i> = 0.609), blood loss (100.0 vs. 200.0 mL, <i>P</i> = 0.734), transfusion rate (4.3% vs. 10.4%, <i>P</i> = 0.374), duration of parenchyma transection (90.0 vs. 72.4 min, <i>P</i> = 0.673), and mean nonparenchymal transection time (191.0 vs. 125.0 min, <i>P</i> = 0.228), without increasing the conversion rate (0.0% vs. 3.9%, <i>P</i> = 0.336), postoperative complications (30.3% vs. 33.8%, <i>P</i> = 0.488), and postoperative hospital stay (6 vs. 7 days, <i>P</i> = 0.060) in AS group and non-AS groups.</p><p><strong>Conclusion: </strong>History of previous nonhepatectomy AS can lead to longer nonparenchymal transection time instead of conversion and did not increase the difficulty. Prolonged nonparenchymal transection time did not increase the surgical complications, prolong the postoperative hospital stay, and compromise the survival outcomes.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"247-252"},"PeriodicalIF":1.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e9/09/TCMJ-35-247.PMC10399838.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of oral anticoagulant use before visit for patients with COVID-19 on mortality: A meta-analysis. COVID-19患者就诊前口服抗凝剂对死亡率的影响:一项荟萃分析
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-07-01 DOI: 10.4103/tcmj.tcmj_199_22
Cornelia Ghea, Ardyan Wardhana, Alfredo Nugroho, Fika Humaeda Assilmi
{"title":"The effect of oral anticoagulant use before visit for patients with COVID-19 on mortality: A meta-analysis.","authors":"Cornelia Ghea,&nbsp;Ardyan Wardhana,&nbsp;Alfredo Nugroho,&nbsp;Fika Humaeda Assilmi","doi":"10.4103/tcmj.tcmj_199_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_199_22","url":null,"abstract":"<p><strong>Objectives: </strong>Anticoagulants have been used as therapeutic or prophylactic agents in COVID-19 and seem to be more beneficial. However, the advantage of oral anticoagulant (OAC) consumption before visit in lowering mortality in COVID-19 patients remains debatable. This meta-analysis aimed to evaluate the effect of OAC use before visit on mortality using the hazard ratio (HR) to estimate the effect of time-to-event endpoints.</p><p><strong>Materials and methods: </strong>We conducted a literature search in the PubMed and ProQuest databases for any studies comparing groups consuming OAC to no-OAC before visit for mortality in patients with COVID-19. We calculated the overall HRs and their variances across the studies using the random-effects model to obtain pooled estimates.</p><p><strong>Results: </strong>We included 12 studies which had sample sizes ranging from 70 to 459,402 patients. A meta-analysis comparing OAC therapy and non-OAC consumption in COVID-19 patients before visit revealed no decrease in all-cause mortality (HR = 0.92, 95% confidence interval [CI]: 0.83-1.02, <i>P</i> = 0.12; <i>I</i><sup>2</sup> = 68%). However, subgroup analysis of laboratory-confirmed populations revealed that OAC use before visit had a beneficial effect on mortality (HR = 0.84, 95% CI: 0.73-0.98, <i>P</i> = 0.02; <i>I</i><sup>2</sup> = 56%).</p><p><strong>Conclusion: </strong>The use of OAC before visit had no beneficial effect on all-cause mortality in COVID-19 patients.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"226-230"},"PeriodicalIF":1.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/81/TCMJ-35-226.PMC10399847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10308305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An innovation percutaneous needle knife use for trigger finger: A retrospective cohort study. 一种创新的经皮针刺刀用于扳机指:一项回顾性队列研究。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-07-01 DOI: 10.4103/tcmj.tcmj_277_22
Bharath Kumar Velmurugan, Chih-Yang Huang, Dah-Ching Ding, Kun-Chi Wu
{"title":"An innovation percutaneous needle knife use for trigger finger: A retrospective cohort study.","authors":"Bharath Kumar Velmurugan,&nbsp;Chih-Yang Huang,&nbsp;Dah-Ching Ding,&nbsp;Kun-Chi Wu","doi":"10.4103/tcmj.tcmj_277_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_277_22","url":null,"abstract":"<p><strong>Objectives: </strong>This study retrospectively evaluated the effectiveness of percutaneous pulley release by our newly designed needle knife in terms of cure, relapse, and complication rates.</p><p><strong>Materials and methods: </strong>Two hundred and fifty-seven patients were allocated into male and female groups between October 2014 and September 2021. We included patients >15 years of age with a trigger finger (TF) (types II-VI). The primary outcome was the absence of a TF and pain-free movement. In contrast, the secondary outcome included second-time surgery and the number of complications such as infection and admission for antibiotics.</p><p><strong>Results: </strong>One hundred patients were male, and 157 patients were female. Males and females had mean ages of 62.45 ± 11.76 and 61.50 ± 8.57 years, respectively. The operative time was significantly longer in males than in females (7.88 ± 6.02 vs. 6.52 ± 3.74 min in males and females, respectively, <i>P</i> = 0.027). However, the percentages of diabetes mellitus and gout were the same in both groups. For the percutaneous methods with our needle knife, remission of the trigger was achieved in all cases. In addition, seven patients received revision and three patients with complications. After needle surgery, topical and joint pain scores were improved in both groups (from 5.09 ± 1.31 to 0.80 ± 1.56).</p><p><strong>Conclusion: </strong>The percutaneous methods with our needle knife displayed effectiveness. The cure rate was high, and the relapse rate was low. Further large-scale clinical trials comparing percutaneous needle to open surgery for releasing the TF will be needed to confirm our results.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"242-246"},"PeriodicalIF":1.5,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/ba/TCMJ-35-242.PMC10399844.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum: Comparison of surgical outcome between conventional open thyroidectomy and endoscopic thyroidectomy through axillo-breast approach. 更正:传统开放式甲状腺切除术与经腋窝-乳房入路的内窥镜甲状腺切除术的手术效果比较。
IF 1.4
Tzu Chi Medical Journal Pub Date : 2023-06-24 eCollection Date: 2023-07-01 DOI: 10.4103/1016-3190.379461
{"title":"Corrigendum: Comparison of surgical outcome between conventional open thyroidectomy and endoscopic thyroidectomy through axillo-breast approach.","authors":"","doi":"10.4103/1016-3190.379461","DOIUrl":"10.4103/1016-3190.379461","url":null,"abstract":"<p><p>[This corrects the article on p. 286 in vol. 32.].</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"277"},"PeriodicalIF":1.4,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/0d/TCMJ-35-277.PMC10399848.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential benefits of spinal cord stimulation treatment on quality of life for paralyzed patients with spinal cord injury. 脊髓刺激治疗对脊髓损伤瘫痪患者生活质量的潜在益处。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-04-01 DOI: 10.4103/tcmj.tcmj_102_22
Xiang-Ling Huang, Yu-Chen Chen, Chang-Chih Kuo, Sheng-Tzung Tsai
{"title":"Potential benefits of spinal cord stimulation treatment on quality of life for paralyzed patients with spinal cord injury.","authors":"Xiang-Ling Huang,&nbsp;Yu-Chen Chen,&nbsp;Chang-Chih Kuo,&nbsp;Sheng-Tzung Tsai","doi":"10.4103/tcmj.tcmj_102_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_102_22","url":null,"abstract":"<p><p>Spinal cord injury (SCI) is a severe central nervous system injury that can cause sensory or motor dysfunction. Although mortality rates for people with spinal cord injuries have dropped dramatically with advances in medicine, chronic long-term sequelae after SCI persist. The most bothersome problems reported by patients include pain, spasticity, urinary dysfunction, and loss of motor function. Thus, quality of life (QoL) is an essential issue in chronic SCI. Spinal cord stimulation (SCS) applies an adjustable, nondamaging electrical pulse that can reduce uncomfortable comorbidities and improve mobility, thus enhancing the QoL of patients with SCI. This review summarizes pivotal breakthroughs from SCS for individual clinical impairment from SCI. We conclude that careful evaluation of SCS can help improve neuropathic pain, spasms, motor symptoms, and voiding dysfunction in patients with SCI, thus improving QoL.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"131-136"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/0d/TCMJ-35-131.PMC10227680.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of hierarchical database access control for E-medicine systems. 电子医疗系统的分层数据库访问控制综述。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-04-01 DOI: 10.4103/tcmj.tcmj_124_22
Tian-Fu Lee, Jyun-Guo Wang, Yen-Chang Chen
{"title":"Review of hierarchical database access control for E-medicine systems.","authors":"Tian-Fu Lee,&nbsp;Jyun-Guo Wang,&nbsp;Yen-Chang Chen","doi":"10.4103/tcmj.tcmj_124_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_124_22","url":null,"abstract":"<p><p>Key management schemes for hierarchical access control enable users who have hierarchical relationships with each other to manage their secret keys efficiently. In these schemes, the users are divided into several groups, and all groups have their own central authorities. Each central authority is responsible for setting parameters and generating user's secret keys in a hierarchical structure such that all users efficiently derive their secret keys and solve dynamic access control problems. Several key management schemes with Health Insurance Portability Accountability Act regulations were recently proposed for hierarchical access control in e-medicine systems. However, these schemes either are insecure or require a large amount of storage and heavy computations. Therefore, this study reviews and discusses hierarchical access control schemes with privacy/security regulations for medical record databases.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"143-147"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/a0/TCMJ-35-143.PMC10227688.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of anthropometric and sociodemographic variables on physical activity levels of people living with human immunodeficiency virus/acquired immunodeficiency syndrome on highly active antiretroviral therapy. 人体测量学和社会人口学变量对人体免疫机能丧失病毒/获得性免疫机能丧失综合症患者接受高活性抗逆转录病毒治疗时身体活动水平的影响
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-04-01 DOI: 10.4103/tcmj.tcmj_180_22
Jane Nwanneka Anikpe, Aroh Joseph Chukwu, Ekom Ndifreke Edem, Adel A E Elahmar, Sohini Sinha, David Arome
{"title":"Effect of anthropometric and sociodemographic variables on physical activity levels of people living with human immunodeficiency virus/acquired immunodeficiency syndrome on highly active antiretroviral therapy.","authors":"Jane Nwanneka Anikpe,&nbsp;Aroh Joseph Chukwu,&nbsp;Ekom Ndifreke Edem,&nbsp;Adel A E Elahmar,&nbsp;Sohini Sinha,&nbsp;David Arome","doi":"10.4103/tcmj.tcmj_180_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_180_22","url":null,"abstract":"<p><strong>Objectives: </strong>Physical inactivity plays a major role in promoting disease outcome, but physical activity enhances effective prevention and treatment of chronic diseases; hence, this study was to determine the effect of anthropometric and demographic factors on the physical activity level of people living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) on antiretroviral therapy.</p><p><strong>Materials and methods: </strong>This study adopted a cross-sectional method of descriptive research design. A sample size of 170 participants was recruited for this research comprising 113 females and 57 males, who after obtaining their informed consent were issued questionnaires which they meticulously filled under a proper guidance. The participants were almost proportionally distributed across the three levels of physical activity, though about half of them had a normal weight of body mass index (BMI) based on the information obtained.</p><p><strong>Results: </strong>The study showed that physical activity according to age significantly affected the BMI (<i>P</i> < 0.05). Physical activity level according to gender had no statistically significant effect on BMI of people living with HIV/AIDS on antiretroviral drugs (<i>P</i> > 0.05). However, it was observed that gender had a significant determining effect on BMI, though not related to PAL.</p><p><strong>Conclusions: </strong>The findings possibly imply that the psychological effect and the stigma may be the determining factors for the unwillingness to engage in physical activities. This calls for a renewed sensitization and orientation in this aspect.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"200-204"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/c2/TCMJ-35-200.PMC10227687.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9565965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-inflammatory and memory-enhancing properties of Chinese herbal extracts: The possible application in Alzheimer's disease. 中药提取物的抗炎和增强记忆特性:在阿尔茨海默病中的可能应用。
IF 1.5
Tzu Chi Medical Journal Pub Date : 2023-04-01 DOI: 10.4103/tcmj.tcmj_139_22
Peeraporn Varinthra, Pavithra Suresh, Prithiviraj Chokkalingam, Ayooluwa Gabriel Ibiayo, Ingrid Y Liu
{"title":"Anti-inflammatory and memory-enhancing properties of Chinese herbal extracts: The possible application in Alzheimer's disease.","authors":"Peeraporn Varinthra,&nbsp;Pavithra Suresh,&nbsp;Prithiviraj Chokkalingam,&nbsp;Ayooluwa Gabriel Ibiayo,&nbsp;Ingrid Y Liu","doi":"10.4103/tcmj.tcmj_139_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_139_22","url":null,"abstract":"Alzheimer's disease (AD) is a progressive brain disease that causes cognitive impairment in seniors. The beta-amyloid (Aβ) deposition and intracellular neurofibrillary tangles are two pathological hallmarks of AD. The increase of AD hallmarks causes inflammatory response enhancement, reduction of synaptic plasticity, and impaired cognition. The percentage of the aging population is growing along with the number of AD patients; however, effective treatment of AD is still limited. Therefore, developing preventive and therapeutic drugs for AD with fewer adverse side effects is urgently needed. The crude extracts from herbs such as Centella asiatica, Dendrobium catenatum, Litsea cubeba, Nardostachys jatamansi, Convolvulus pluricaulis, Melissa officinalis, Magnolia officinalis, Withania somnifera, and Nigella sativa improved memory performance and reduced inflammation response in various diseases. In addition, herbal blends usually have minimum aversive effects and can be mixed into diet and served as nutritional supplements. Hence, it is promising to develop Chinese herbal extracts to prevent or treat early AD. This review article highlights the currently available treatments of AD and the therapeutic effects of a group of crude extracts from Chinese herbs that can prevent cognitive decline and reduce the excessive inflammatory response. The possible clinical use of these Chinese herbal extracts in AD is also discussed.","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"103-110"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/63/TCMJ-35-103.PMC10227682.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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