Tzu Chi Medical Journal最新文献

{"title":"Corrigendum: Comparison of surgical outcome between conventional open thyroidectomy and endoscopic thyroidectomy through axillo-breast approach.","authors":"","doi":"10.4103/1016-3190.379461","DOIUrl":"10.4103/1016-3190.379461","url":null,"abstract":"<p><p>[This corrects the article on p. 286 in vol. 32.].</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 3","pages":"277"},"PeriodicalIF":1.4,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/0d/TCMJ-35-277.PMC10399848.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential benefits of spinal cord stimulation treatment on quality of life for paralyzed patients with spinal cord injury.","authors":"Xiang-Ling Huang,&nbsp;Yu-Chen Chen,&nbsp;Chang-Chih Kuo,&nbsp;Sheng-Tzung Tsai","doi":"10.4103/tcmj.tcmj_102_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_102_22","url":null,"abstract":"<p><p>Spinal cord injury (SCI) is a severe central nervous system injury that can cause sensory or motor dysfunction. Although mortality rates for people with spinal cord injuries have dropped dramatically with advances in medicine, chronic long-term sequelae after SCI persist. The most bothersome problems reported by patients include pain, spasticity, urinary dysfunction, and loss of motor function. Thus, quality of life (QoL) is an essential issue in chronic SCI. Spinal cord stimulation (SCS) applies an adjustable, nondamaging electrical pulse that can reduce uncomfortable comorbidities and improve mobility, thus enhancing the QoL of patients with SCI. This review summarizes pivotal breakthroughs from SCS for individual clinical impairment from SCI. We conclude that careful evaluation of SCS can help improve neuropathic pain, spasms, motor symptoms, and voiding dysfunction in patients with SCI, thus improving QoL.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"131-136"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/0d/TCMJ-35-131.PMC10227680.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of hierarchical database access control for E-medicine systems.","authors":"Tian-Fu Lee,&nbsp;Jyun-Guo Wang,&nbsp;Yen-Chang Chen","doi":"10.4103/tcmj.tcmj_124_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_124_22","url":null,"abstract":"<p><p>Key management schemes for hierarchical access control enable users who have hierarchical relationships with each other to manage their secret keys efficiently. In these schemes, the users are divided into several groups, and all groups have their own central authorities. Each central authority is responsible for setting parameters and generating user's secret keys in a hierarchical structure such that all users efficiently derive their secret keys and solve dynamic access control problems. Several key management schemes with Health Insurance Portability Accountability Act regulations were recently proposed for hierarchical access control in e-medicine systems. However, these schemes either are insecure or require a large amount of storage and heavy computations. Therefore, this study reviews and discusses hierarchical access control schemes with privacy/security regulations for medical record databases.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"143-147"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b3/a0/TCMJ-35-143.PMC10227688.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of anthropometric and sociodemographic variables on physical activity levels of people living with human immunodeficiency virus/acquired immunodeficiency syndrome on highly active antiretroviral therapy.","authors":"Jane Nwanneka Anikpe,&nbsp;Aroh Joseph Chukwu,&nbsp;Ekom Ndifreke Edem,&nbsp;Adel A E Elahmar,&nbsp;Sohini Sinha,&nbsp;David Arome","doi":"10.4103/tcmj.tcmj_180_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_180_22","url":null,"abstract":"<p><strong>Objectives: </strong>Physical inactivity plays a major role in promoting disease outcome, but physical activity enhances effective prevention and treatment of chronic diseases; hence, this study was to determine the effect of anthropometric and demographic factors on the physical activity level of people living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) on antiretroviral therapy.</p><p><strong>Materials and methods: </strong>This study adopted a cross-sectional method of descriptive research design. A sample size of 170 participants was recruited for this research comprising 113 females and 57 males, who after obtaining their informed consent were issued questionnaires which they meticulously filled under a proper guidance. The participants were almost proportionally distributed across the three levels of physical activity, though about half of them had a normal weight of body mass index (BMI) based on the information obtained.</p><p><strong>Results: </strong>The study showed that physical activity according to age significantly affected the BMI (<i>P</i> < 0.05). Physical activity level according to gender had no statistically significant effect on BMI of people living with HIV/AIDS on antiretroviral drugs (<i>P</i> > 0.05). However, it was observed that gender had a significant determining effect on BMI, though not related to PAL.</p><p><strong>Conclusions: </strong>The findings possibly imply that the psychological effect and the stigma may be the determining factors for the unwillingness to engage in physical activities. This calls for a renewed sensitization and orientation in this aspect.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"200-204"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/c2/TCMJ-35-200.PMC10227687.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9565965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-inflammatory and memory-enhancing properties of Chinese herbal extracts: The possible application in Alzheimer's disease.","authors":"Peeraporn Varinthra,&nbsp;Pavithra Suresh,&nbsp;Prithiviraj Chokkalingam,&nbsp;Ayooluwa Gabriel Ibiayo,&nbsp;Ingrid Y Liu","doi":"10.4103/tcmj.tcmj_139_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_139_22","url":null,"abstract":"Alzheimer's disease (AD) is a progressive brain disease that causes cognitive impairment in seniors. The beta-amyloid (Aβ) deposition and intracellular neurofibrillary tangles are two pathological hallmarks of AD. The increase of AD hallmarks causes inflammatory response enhancement, reduction of synaptic plasticity, and impaired cognition. The percentage of the aging population is growing along with the number of AD patients; however, effective treatment of AD is still limited. Therefore, developing preventive and therapeutic drugs for AD with fewer adverse side effects is urgently needed. The crude extracts from herbs such as Centella asiatica, Dendrobium catenatum, Litsea cubeba, Nardostachys jatamansi, Convolvulus pluricaulis, Melissa officinalis, Magnolia officinalis, Withania somnifera, and Nigella sativa improved memory performance and reduced inflammation response in various diseases. In addition, herbal blends usually have minimum aversive effects and can be mixed into diet and served as nutritional supplements. Hence, it is promising to develop Chinese herbal extracts to prevent or treat early AD. This review article highlights the currently available treatments of AD and the therapeutic effects of a group of crude extracts from Chinese herbs that can prevent cognitive decline and reduce the excessive inflammatory response. The possible clinical use of these Chinese herbal extracts in AD is also discussed.","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"103-110"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/63/TCMJ-35-103.PMC10227682.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nail-stem construct method for periprosthetic humeral fractures with recalcitrant nonunion after total elbow arthroplasty: A surgical technique.","authors":"Yen-Sheng Chiang,&nbsp;Shih-Hao Chen,&nbsp;Keng-Chang Liu,&nbsp;Chang-Chen Yang,&nbsp;Jui-Teng Chien","doi":"10.4103/tcmj.tcmj_193_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_193_22","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to describe the surgical technique using an innovative nail-stem construct in treatment of periprosthetic humeral fractures with recalcitrant nonunion after total elbow arthroplasty (TEA).</p><p><strong>Materials and methods: </strong>Patients diagnosed with humeral recalcitrant nonunion in periprosthetic fractures and stem loosening after TEA were retrospectively recruited between 2018 and 2019. The demographic data and related clinical outcomes were recorded. We use a cutting length of the nail pushing into the humeral canal and then pull back distally to dock the tip of the humeral stem. The cement was packed into the humeral canal, and the periprosthetic bone defect was impacting with harvested allograft chip.</p><p><strong>Results: </strong>Patient age, gender, lesion site, number of previous surgeries, and the time period from the primary TEA to the nail-stem reconstruction were allocated. Moreover, the range of motion, degree of elbow stability, and level of pain were evaluated for each patient following this procedure. All the four patients achieved an optimal range of motion and secure stability with painless elbow at final follow-up.</p><p><strong>Conclusion: </strong>Our proposed nail-stem construct with double allogenous bone plate is a feasible alternative for revisional TEA in patients with implant loosening, periprosthetic humeral fractures, and recalcitrant nonunion.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"171-175"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/36/TCMJ-35-171.PMC10227686.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem-cell therapy in stress urinary incontinence: A review.","authors":"Pei-Chen Li,&nbsp;Dah-Ching Ding","doi":"10.4103/tcmj.tcmj_145_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_145_22","url":null,"abstract":"<p><p>The incidence of urinary incontinence (UI) is approximately 10%-40% in women, affecting one to two hundred million women worldwide. Stress UI (SUI) is characterized by involuntary urination due to increased abdominal stress and urine leakage without bladder contraction. Surgical treatments include midurethral slings, bulking agents, and Burch colposuspension to restore urethral continence. Nevertheless, an optimal treatment for all types of incontinence has not yet been established. Stem-cell therapy has emerged as a novel treatment for many diseases. Stem cells can self-renew and can differentiate into other cell types. Adult stem cells are suitable for clinical applications because they can be easily obtained noninvasively or minimal invasively. Stem-cell therapy for SUI has been studied preclinically and clinically. Muscle-derived progenitors have been used to treat SUI by promoting the regeneration of rhabdomyosphincters. The human trial used transurethral injection of autologous muscle-derived stem cells to improve sphincter contractility and function. Other sources of stem cells have also been studied in SUI treatment, such as umbilical cord blood, amniotic fluid, bone marrow, urine, and adipose tissue. The success rate of stem-cell therapy for SUI ranges from 13% to 100%. This review aimed to summarize the current status of stem-cell treatments for SUI, with respect to clinical trials, cell types, transplantation routes, and dosage volume and frequency.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"111-119"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/9e/TCMJ-35-111.PMC10227685.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9565967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia and impairment in global cognitive, delayed memory, and olfactory function, among community-dwelling adults, in Jakarta, Indonesia: Active aging study.","authors":"Yvonne Suzy Handajani,&nbsp;Elisabeth Schröder Butterfill,&nbsp;Antoninus Hengky,&nbsp;Sagita Pratiwi Sugiyono,&nbsp;Vincent Lamadong,&nbsp;Yuda Turana","doi":"10.4103/tcmj.tcmj_175_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_175_22","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the association of sarcopenia among community-dwelling older adults with chronic conditions, lipid profiles, and cognitive ability measured by multiple assessment tools.</p><p><strong>Materials and methods: </strong>This cross-sectional study involved 398 older adults aged 60 years and older who resided in Jakarta, Indonesia. The study participants were visited and interviewed by trained interviewers in the subdistrict office. Participants were clinically examined using a standardized protocol, which included the participants' medical history, general physical examination, cognitive assessment, and blood test for lipid profile. Sarcopenia was measured using three components that were muscle strength (measured by handgrip strength), physical performance (measured by 6-m walk speed), and appendicular skeletal mass (measured using bioelectrical impedance analysis). Association was tested using multivariate logistic regression and reported as an odds ratio.</p><p><strong>Results: </strong>Sarcopenia was significantly associated with older age (adjusted odd ratio [AOR]: 2.91, 95% confidence interval [CI]: 1.22-3.95) and smoking (AOR: 6.53, 95% CI: 2.89-14.73). Global cognitive impairment, word list recall impairment, and olfactory dysfunction have 191% (95% CI: 1.28-6.66), 141% (95% CI: 1.12-5.2), and 100% (95% CI: 1.11-3.61) increase of odds of having sarcopenia, respectively.</p><p><strong>Conclusion: </strong>Global cognitive impairment, word list recall impairment, and olfactory dysfunction could be the predictors of sarcopenia. Strategies and implementations directed more toward the improvement of cognitive impairment might improve or prevent sarcopenia. However, the exact causality between both variables still needs to be explored further.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"193-199"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/57/87/TCMJ-35-193.PMC10227675.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive performance of qSOFA in confirmed COVID-19 patients presenting to the emergency department.","authors":"Farhad Heydari,&nbsp;Saeed Abbasi,&nbsp;Kiana Shirani,&nbsp;Majid Zamani,&nbsp;Babak Masoumi,&nbsp;Saeed Majidinejad,&nbsp;Mohammad Nasr-Esfahani,&nbsp;Mahsa Sadeghi-Aliabadi,&nbsp;Mohammadreza Arbab","doi":"10.4103/tcmj.tcmj_132_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_132_22","url":null,"abstract":"<p><strong>Objectives: </strong>It is critical to quickly and easily identify coronavirus disease 2019 (COVID-19) patients who become severely or even critically ill. Thus, this study was conducted to determine the accuracy of the quick Sequential Organ Failure Assessment (qSOFA) score in predicting the severity and mortality of COVID-19 patients.</p><p><strong>Materials and methods: </strong>This was a prospective observational study of COVID-19 patients admitted to the emergency department (ED) between June 22, 2021, and November 21, 2021. The clinical characteristics of the participants were collected by the emergency physicians. The correlation of the qSOFA, Systemic Inflammatory Response Syndrome criteria (SIRS), Pneumonia Severity Index (PSI), and confusion, urea, respiratory rate, blood pressure, 65 years of age and older (CURB-65) scores for 14-day mortality were evaluated. The area under a receiver operating characteristic (AUROC) curve analysis was calculated to compare the effectiveness of qSOFA, SIRS, PSI, and CURB-65 to predict severe disease.</p><p><strong>Results: </strong>Eight hundred and ninety-four subjects were included. Of them, 721 patients (80.6%) survived after 14 days of admission. The mean age was 58.92 ± 17.80 years, and 551 subjects (61.6%) were male. Nonsurvived patients were significantly older (51.09 ± 23.60 vs. 38.10 ± 18.24, <i>P</i> = 0.004) and had more comorbidities (diabetes mellitus, respiratory, cardiovascular, and cerebrovascular disease) in comparison with survived patients. For COVID-19 mortality prediction, the AUROCs of qSOFA, CURB-65, PSI, and SIRS score were 0.799 (95% confidence interval [CI 0.771-0.825]), 0.829 (95% CI [0.803-0.853]), 0.830 (95% CI [0.804-0.854]), and 0.759 (95% CI [0.730-0.787]), respectively. All scores were good predictors of COVID-19 mortality.</p><p><strong>Conclusion: </strong>The qSOFA was more successful than SIRS in predicting mortality for COVID-19 patients and was similar to CURB-65 and PSI. Therefore, the qSOFA score can be considered a simple and rapid screening tool for identifying high-risk patients.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"182-187"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dd/77/TCMJ-35-182.PMC10227679.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network pharmacology implicates traditional Chinese medicine in regulating systemic homeostasis to benefit Alzheimer's disease.","authors":"Sheng-Tzung Tsai,&nbsp;Hsin-Yi Huang","doi":"10.4103/tcmj.tcmj_125_22","DOIUrl":"https://doi.org/10.4103/tcmj.tcmj_125_22","url":null,"abstract":"<p><p>Traditional Chinese medicine (TCM) has the characteristics of multi-component, multi-target, and biological systems coordination, which meet the criteria of the network pharmacological application. Therefore, using network pharmacology to discover the relationship between TCM, diseases, and cellular responses is easily achievable. Aging-induced imbalanced homeostasis is a risk factor for Alzheimer's disease (AD), a neuronal disease regulated by multiple genes. Meta-analysis of TCM in metabolic regulation to improve symptoms of AD helps understand the pharmacological effects. The drug targets of TCM can be investigated using a holistic network pharmacology approach to find potential modulators involved in AD-related metabolic pathways. Based on the theoretical prediction of TCM for AD, experimental validation is needed to develop pure compounds for specific treatments.</p>","PeriodicalId":45873,"journal":{"name":"Tzu Chi Medical Journal","volume":"35 2","pages":"120-130"},"PeriodicalIF":1.5,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9c/74/TCMJ-35-120.PMC10227678.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9565968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}