International Journal of Veterinary Science and Medicine最新文献

{"title":"Seroprevalence of Newcastle disease virus in backyard chickens and herd-level risk factors of Newcastle disease in poultry farms in Oman","authors":"Ali Alsahami ,&nbsp;Aini Ideris ,&nbsp;Abdulrahman Omar ,&nbsp;Siti Zubaidah Ramanoon ,&nbsp;Mohammed Babatunde Sadiq","doi":"10.1016/j.ijvsm.2018.06.004","DOIUrl":"10.1016/j.ijvsm.2018.06.004","url":null,"abstract":"<div><p>Newcastle disease (ND) is an endemic disease in Oman’s poultry industry and impacts negatively on food security. However, little is known regarding the potential risks of the disease in backyard poultry. The objectives of this study were to determine the seroprevalence of Newcastle disease virus (NDV) in backyard chickens and the herd-level risk factors in Oman. In total, 1383 serum samples were collected from chickens in 139 flocks from nine governorates. Information on associated risk factors was assessed using a semi-structured questionnaire. The samples were tested using commercial indirect ELISA kits.A logistic regression model was applied to assess the associated risk factors. The bird and flock-level NDV seroprevalence was 33.8% (95% Confidence Interval (CI): 12.8–38.6%) and 57.1% (95% CI: 35.7–71.4%), respectively. The highest seroprevalence of antibody to NDV at bird and flock levels was recorded in North Ash Sharqiyah (38.6%) and Al Buraimi (71.4%), respectively. Also, the lowest seroprevalence at bird and flock levels was recorded in Musandam (12.8%) and South Al Batinah (35.7%), respectively. A significant difference in NDV seroprevalence at flock and bird levels was only recorded in Ad Dakhliyah. Factors associated with higher seroprevalence to NDV included absence of a veterinarian in the farm (OR = 5.3; 95% CI: 2.1, 11.7), usage of dead ND vaccine (OR = 2.3; 95% CI: 1.2–4.2), employment of non-permanent staff (OR = 3.9; 95% CI: 1.5, 10.6) and free entry of visitors (OR = 6.2; 95% CI: 2.0, 20.3). In conclusion, the results of this study revealed a high exposure of backyard chickens to NDV and the identified risk factors could be vital in the prevention and control of the disease in Oman.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 186-191"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.06.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotyping of Streptococcus uberis isolates in healing process of bovine clinical mastitis","authors":"Christina Werner ,&nbsp;Claudia Sauerwald ,&nbsp;Albert Sundrum ,&nbsp;Amr El-Sayed ,&nbsp;Michael Zschöck","doi":"10.1016/j.ijvsm.2018.09.005","DOIUrl":"10.1016/j.ijvsm.2018.09.005","url":null,"abstract":"<div><p>In the present work, macrorestriction analysis was applied to characterize 44 <em>S. uberis</em> field strains isolated from lactating cows suffering from mastitis in three dairy herds in Hesse State, Germany. Analysis of the obtained data by Pulse-Field Gel Electrophoresis (PFGE) showed that most of the isolates originating from different herds and cows were not related to each other. However, identical macrorestriction patterns were noted in 12 of 13 mastitic quarters in healing process, in three quarters even over the whole sampling period indicating persistent infection. In the present work, PFGE could detect variable levels of similarity ranging from 76 to 100%. The macrorestriction analyses revealed the presence of 10 <em>S. uberis</em> PFGE pattern with more than four bands difference. PFGE profiles with minor differences (only one to three bands) were considered to be subtypes. The use of sensitive genotyping methods like macrorestriction analyses by PFGE enables the differentiation among new and persistent infections. Nevertheless minor changes in macrorestriction profiles could occur which are clearly distinguishable from totally unrelated strains.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 274-278"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.09.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36838559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonography guidance for total splenectomy in donkeys","authors":"Kamal-Eldeen Fouad,&nbsp;Sayed Elzomor,&nbsp;Haithem A.M. Farghali,&nbsp;Ibrahim A. Emam","doi":"10.1016/j.ijvsm.2018.10.001","DOIUrl":"10.1016/j.ijvsm.2018.10.001","url":null,"abstract":"<div><p>There are varieties of surgical approaches reported for equine splenectomy and all of them were dealing with the most reachable situation of splenic hilus and easy handling of the spleen. The aim of this work was to establish the normal ultrasound parameters of spleen in donkeys (normal echogenicity, hilus situation, topographic location and correlation with neighboring organs) as a guide to select the best approach for total splenectomy in donkeys. Splenic ultrasound was carried out on six normal donkeys before experimental total splenectomy in the standing position. The splenic topographic location was recorded among 4 rows including 30 squares. These animals were divided into two groups according to the surgical approach of total splenectomy. Total splenectomy after left 16^th and 17^th ribs partial resection in standing position was carried out in group1 and group 2, respectively. Ultrasonographically, the spleen had homogenously echogenic pattern and appeared hyperechoic to the liver. Only one third of the spleen was located in front of the 16^th rib where the hilus and splenic blood vessels were nearly under the 16^th rib. The splenic artery and splenic vein were ultrasonographically visualized between the left 16^th and 17^th ribs 10–15 cm from dorsal midline. This area was the site of the important ligation during total splenectomy. In conclusion, ultrasonography guidance for total splenectomy in donkeys assisted the surgical findings and proved that technique following partial resection of the 17^th rib at the standing position is the most convenient surgical approach for total splenectomy in donkeys.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 233-238"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Populations of Eimeria tenella express resistance to commonly used anticoccidial drugs in southern Nigeria","authors":"Agatha E. Ojimelukwe,&nbsp;Deborah E. Emedhem,&nbsp;Gabriel O. Agu,&nbsp;Florence O. Nduka,&nbsp;Austin E. Abah","doi":"10.1016/j.ijvsm.2018.06.003","DOIUrl":"10.1016/j.ijvsm.2018.06.003","url":null,"abstract":"<div><p>Coccidiosis is one of the most economically important diseases of poultry. This study determined the preponderance of chicken <em>Eimeria</em> in southern Nigeria and assessed the parasite’s resistance to three anticoccidial drugs: Amprolium hydrochloride; Amprolium hydrochloride + Sulfaquinoxaline-Sodium; and Toltrazuril. Multiplex PCR amplification of the SCAR region was used to confirm <em>Eimeria</em> preponderance. Resistance was assessed following the inoculation of 2.32 × 10⁵ infective oocysts into broilers. Data on weight gain, feed intake, feed conversion and fecal oocyst shed were recorded. At 7 days post inoculation 9 birds per treatment were sacrificed and assessed for macroscopic lesions in four intestinal regions. Percent optimum anticoccidial activity (POAA), Anticoccidial index (ACI) and Anticoccidial sensitivity test (AST) were used to access resistance. The preponderance of <em>Eimeria</em> spp. were <em>E. tenella</em> (77%), <em>E. necatrix</em> (55%), <em>E. acervulina</em> (44%) and <em>E. mitis</em> (11%), with multi-species infection occurring in 55% of samples assessed. Fecal oocyst shedding was low (<em>P</em> &lt; 0.05) in the medicated groups. Lesions in the cecal region were present in all infected groups regardless of treatment and accounted for 27.8% of lesion scores by severity and 37.5% of lesion scores by frequency. Overall, lesion scores were less (<em>P</em> &lt; 0.05) in birds of the medicated groups compared with the infected-unmedicated group. The high preponderance of <em>E. tenella</em> in the field, and the occurrence of cecal lesions – caused mainly by <em>E. tenella</em>- despite drug administration, indicate resistance in populations of this species in our isolate. Based-on the POAA, ACI and AST values, the <em>Eimeria</em> isolate showed reduced sensitivity to toltrazuril.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 192-200"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.06.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinoic acid improves maturation rate and upregulates the expression of antioxidant-related genes in in vitro matured buffalo (Bubalus bubalis) oocytes","authors":"Ahmed Gad ,&nbsp;Said Abu Hamed ,&nbsp;Mohamed Khalifa ,&nbsp;Ahmed Amin ,&nbsp;Ashraf El-Sayed ,&nbsp;Swiefy A. Swiefy ,&nbsp;Salah El-Assal","doi":"10.1016/j.ijvsm.2018.09.003","DOIUrl":"10.1016/j.ijvsm.2018.09.003","url":null,"abstract":"<div><p>Retinoic acid, vitamin A metabolite, plays a role in oocyte development and maturation in different ways including gene expression alteration and/or prohibiting oxidative stress. The objective of this study was to examine the effect of 9-cis-retinoic acid (9-cisRA) on the quality and maturation rate of buffalo oocytes. Cumulus-oocyte complexes (COCs, n = 460) were collected from ovaries of slaughtered buffalos. Varying concentrations of 9-cisRA (0, 5, 50, and 200 nM) were added to the maturation medium, and the following parameters were analyzed: (i) maturation and cleavage rates, (ii) mitochondrial activity and reactive oxygen species (ROS) levels, (iii) expression level of antioxidant-related genes (<em>PRDX1, SOD1, CAT, HOMX1,</em> and <em>GPX4</em>) using RT-qPCR. Maturation rate was significantly improved in 5 nM 9-cisRA oocyte group (95.8%, <em>P</em> &lt; .05) compared to control and other treatment groups (86.7% in control group). The same oocyte group exhibited significantly higher mitochondrial membrane potential activity and lower ROS accumulation level compared to other treatment groups. Antioxidant-related genes were up-regulated in oocytes matured with 5 or 50 nM 9-cisRA compared to control and 200 nM 9-cisRA groups. In contrast, 200 nM of 9-cisRA showed a clear down-regulation for antioxidant-related genes except for <em>PRDX1</em>. In conclusion, supplementation of 9-cisRA with a lower concentration (5 nM) to the buffalo oocytes maturation media promotes maturation rate through a protection mechanism that maintains adequate levels of antioxidant-related transcripts and improves mitochondrial activity. However, 9-cisRA has no significant effect on the cleavage rate of the treated oocytes.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 279-285"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36838560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave assisted green synthesis of Hydroxyapatite nanorods using Moringa oleifera flower extract and its antimicrobial applications","authors":"V. Kalaiselvi ,&nbsp;R. Mathammal ,&nbsp;S. Vijayakumar ,&nbsp;B. Vaseeharan","doi":"10.1016/j.ijvsm.2018.08.003","DOIUrl":"10.1016/j.ijvsm.2018.08.003","url":null,"abstract":"<div><p>Hydroxyapatite is an important biomaterial and main mineral component found in bones for potential clinical applications. <em>Moringa oleifera,</em> a common plant in which all parts are edible and rich in iron content. This study reported the chemically synthesized Hydroxyapatite and green synthesis of Hydroxyapatite nanorods using the aqueous flower extract of <em>Moringa oleifera</em> by microwave assisted method. The synthesized <em>Moringa oleifera</em> flower extract Hydroxyapatite nanorods were characterized by UV–Vis spectroscopy (UV–vis), Fourier Transform Infra Red spectroscopy (FTIR), X-Ray Diffraction analysis (XRD), Transmission Electron Microscopy (TEM), Photo Luminescence spectroscopy (PL), Thermo Gravimetric analysis (TGA) and Energy Dispersive X-ray analysis (EDX). In addition, the antimicrobial activity of these nanorods was assessed. <em>Moringa oleifera</em> flower extract Hydroxyapatite nanorods were crystalline in nature, rod like structure with a mean particle size of 41 nm. The antibacterial activity of <em>Moringa oleifera</em> flower extract capped Hydroxyapatite nanorods was greater against Gram positive bacteria than Gram negative bacteria. Furthermore, <em>Moringa oleifera</em> extract capped Hydroxyapatite nanorods showed a very good antifungal activity against three common pathogenic fungi including; <em>Candida albicans</em>, <em>Aspergillus fumigatus</em> and <em>Aspergillus niger</em>.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 286-295"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36838561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementary outcomes of betaine on economic and productive performance, some biochemical parameters, and lipoprotein lipase gene expression in finishing male broilers","authors":"Mohamed S. Yusuf ,&nbsp;Adel A. El Nabtiti ,&nbsp;Marwa A. Hassan ,&nbsp;Mostafa A. Mandour","doi":"10.1016/j.ijvsm.2018.11.004","DOIUrl":"10.1016/j.ijvsm.2018.11.004","url":null,"abstract":"<div><p>Egypt’s population is growing with the biggest hurdle facing the Government is to secure animal protein. Broilers provide quality protein of reasonable price. This study was conducted to investigate the outcomes of dietary organic betaine (betafin S4) on productive, epigenetic make up of lipoprotein lipase gene (LPL) promoter, some blood biochemical, and economic parameters in male broilers at finishing period. Eighty one commercial Arbor Acre Plus males, 21 days old, were randomly allocated to three groups, with three replicates each in battery cages under thermo-neutral environment till 42 days. The examined groups received yellow corn-soy basal diet, supplemented with 0 (G1), 1.5 (G2) and 3.0 g (G3) betaine/kg diet, respectively. The mRNA expression levels of LPL gene were analyzed by real-time quantitative PCR. Methylation pattern on LPL gene promoter was determined by bisulfite sequencing. Doses of betaine statistically (<em>P</em> ≤ .05) improved tested performance parameters; while carcass yield % and abdominal fat deposition did not achieve significant changes. The expression of LPL mRNA showed an inverse relationship with betaine dose, which illustrated as a trend toward increase in G2 and decrease in G3. Regarding serum biochemistry, both treated groups when compared to control group revealed a significant improvement (<em>P</em> ≤ .01) in albumin level, simultaneously, a significant increase (<em>P</em> ≤ .05) was recorded in uric acid and triglyceride levels, additionally, strong positive (<em>P</em> ≤ .01) correlation between betaine dose and previously mentioned parameters was reported. Betaine is recommended in finishing male broilers as production costs were reduced by 3.97%–4.37% per kg, respectively. In conclusion, incorporation of 0.15–0.30% organic betaine to male broilers diets during finishing period improves the growth performances.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 213-218"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.11.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro anthelmintic activity of grape pomace extract against gastrointestinal nematodes of naturally infected sheep","authors":"Suelen Carolina Silva Soares ,&nbsp;Gilmar Cotrin de Lima ,&nbsp;Antonio Carlos Laurentiz ,&nbsp;Aline Féboli ,&nbsp;Luciano Alves dos Anjos ,&nbsp;Matheus Souza de Paula Carlis ,&nbsp;Rosimeire da Silva Filardi ,&nbsp;Rosangela da Silva de Laurentiz","doi":"10.1016/j.ijvsm.2018.11.005","DOIUrl":"10.1016/j.ijvsm.2018.11.005","url":null,"abstract":"<div><p>Grape pomace obtained as a byproduct of industrial processing of grapes retains nutrients and substances with anthelmintic potential such as saponins, tannins, and flavonoids. Therefore, this study evaluated the <em>in vitro</em> ovicidal and larvicidal activity of hydroalcoholic grape pomace extract against gastrointestinal nematodes of sheep. The anthelmintic evaluation was performed by <em>in vitro</em> assays with eggs and larvae of nematodes obtained from naturally infected donor sheep. The grape pomace extract showed high <em>in vitro</em> ovicidal and larvicidal activity with LD₅₀ values of 0.30 mg/mL for egg hatching inhibition, 1.01 mg/mL for larval development inhibition and 100% efficacy in larval migration inhibition assays at all concentrations evaluated. The effect of tannins was evaluated by the addition of 50 mg/mL polyvinyl polypyrrolidone to grape pomace extract at the concentration of 12.5 mg/mL. The <em>in vitro</em> ovicidal activity of grape pomace was reduced by only 15% after polyvinyl polypyrrolidone addition, indicating that other phytochemicals also contribute to the ovicidal activity displayed by the extract. Our results demonstrate that grape pomace exhibits <em>in vitro</em> anthelmintic activity, suggesting that, beyond its nutritional potential, this pomace can also be an ally for gastrointestinal nematode control in sheep.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 243-247"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.11.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-infection of highly pathogenic avian influenza and duck hepatitis viruses in Egyptian backyard and commercial ducks","authors":"Shimaa M.G. Mansour ,&nbsp;Haytham Ali ,&nbsp;Reham M. ElBakrey ,&nbsp;Iman E. El-Araby ,&nbsp;David E.B. Knudsen ,&nbsp;Amal A.M. Eid","doi":"10.1016/j.ijvsm.2018.07.004","DOIUrl":"10.1016/j.ijvsm.2018.07.004","url":null,"abstract":"<div><p>Highly pathogenic avian influenza (HPAI) H5N1 virus poses a major challenge to the poultry industry and human health in Egypt. Twenty one households and eight duck farms in Sharkia Province, Egypt were investigated for the presence of avian influenza virus (AIV) and/or duck hepatitis virus 1 (DHV-1). Mortality rates among the investigated farms and yards were, 18.9% (69/365) of native ducks, 60.9% (25/41) of Pekin ducks, 60.2% (6306/10473) of Muscovy ducks and 44.9% (1353/3015) of Mallard ducks. The RT-PCR revealed the circulation of HPAI-H5N1 virus (81/104) among the examined birds with a high percentage in Muscovy (83.7%) and Pekin (83.4%) ducks. Interestingly, co-infection of HPAI and DHV-1 viruses in three ducklings with age of 4–19 days was detected. Severe neurological signs with high mortality were observed in ducklings as early as 4 days of age. Influenza virus antigen was detected in the neurons and glial cells of the brain, hepatocytes, and the intestinal submucosal plexus. Although, genetic characterization of H5N1 isolates revealed HPAIV of clade 2.2.1.2, such increased mortalities and neurological signs regardless of the duck age might imply the natural selection of HPAI in ducks. Crucial monitoring of the disease situation in ducks is essential for the implementation of an effective prevention and control program.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 301-306"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.07.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36795610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipomatosis of the parotid salivary gland: 2 case reports and review of the literature on fat-containing salivary gland lesions","authors":"Ana Rita Serras ,&nbsp;Roberta Rasotto ,&nbsp;Federico Piccinno ,&nbsp;Guido Pisani ,&nbsp;Daniela Murgia","doi":"10.1016/j.ijvsm.2018.06.001","DOIUrl":"10.1016/j.ijvsm.2018.06.001","url":null,"abstract":"<div><p>Two cases of lipomatosis of the parotid salivary gland in two dogs are reported. Both dogs were presented with a slow growing unilateral non-painful mass in the parotid region. The mass measured 12 and 15 cm on the longest axis for case 1 and 2 respectively. Initial incisional biopsies were suggestive of infiltrative lipoma or salivary gland adenocarcinoma. Case 2 underwent head radiographs that showed a soft tissue opacity on the area of the right parotid gland followed by a computed tomography that showed a multi-lobulated infiltrative mass occupying the right parotid gland. Both cases underwent total parotidectomy with an excisional biopsy intent. Surgery on case 1 included total ear canal ablation (TECA). Histology revealed lipomatosis of the parotid gland with a similar admixture of adipocytes and well-differentiated salivary acini on both cases. No recurrence was reported by 4 years for case 1 and by 3 years for case 2. Case 1 developed long-term right-sided facial paralysis and palpebral reflex deficit due to damage of the facial and trigeminal nerve during surgery. The cases are described and the veterinary literature is reviewed in view of the most updated information available in human medicine on fat-containing salivary gland lesions. Considering this literature review, authors recommended these two cases to be classified as lipomatosis of the salivary gland. In conclusion, fat-containing salivary gland lesions should be considered in the list of differential diagnoses in dogs with an enlarged salivary gland and seem to be associated with an excellent prognosis after surgical excision.</p></div>","PeriodicalId":45744,"journal":{"name":"International Journal of Veterinary Science and Medicine","volume":"6 2","pages":"Pages 253-257"},"PeriodicalIF":2.2,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijvsm.2018.06.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36838555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}