AIMS Public Health最新文献

{"title":"Association of meeting 24-hour movement guidelines with low back pain among adults.","authors":"Kaja Kastelic, Nejc Šarabon, Michael D Burnard, Dean Lipovac, Željko Pedišić","doi":"10.3934/publichealth.2023062","DOIUrl":"10.3934/publichealth.2023062","url":null,"abstract":"<p><strong>Background: </strong>According to recently published 24-hour movement guidelines, adults should spend: ≥150 minutes/week in moderate-to-vigorous physical activity (MVPA); <8 hours/day in sedentary behaviour (SB); and 7-9 hours/day sleeping.</p><p><strong>Objective: </strong>We explored the association between meeting these recommendations and low back pain (LBP)-the most common musculoskeletal disorder.</p><p><strong>Methods: </strong>We collected self-reported data from 2333 adults about: MVPA, SB and sleep duration; frequency and intensity of LBP; and sociodemographic and lifestyle characteristics.</p><p><strong>Results: </strong>Meeting a combination of SB and sleep recommendations was associated with lower odds of LBP in the past week and past month (adjusted odds ratio [<i>OR</i>]: 0.64 and 0.52, respectively; <i>p</i> < 0.05 for both). Among LBP sufferers, meeting any combination of recommendations that includes sleep was associated with lower odds of frequent (<i>OR</i> range: 0.49-0.61; <i>p</i> < 0.05 for all) and intense (<i>OR</i> range: 0.39-0.66; <i>p</i> < 0.05 for all) LBP in the past week, while meeting a combination of SB and sleep recommendations or all three recommendations was associated with lower odds of intense LBP in the past month and past year (<i>OR</i> range: 0.50-0.68; <i>p</i> < 0.05 for all). The likelihood of experiencing higher frequency and intensity of LBP decreased with the number of recommendations met (<i>p</i> for linear trend < 0.05).</p><p><strong>Conclusion: </strong>Meeting the SB and sleep recommendations in combination is associated with a lower likelihood of LBP, while adhering to the overall 24-hour movement guidelines or any combination of recommendations that includes sleep is associated with lower frequency and intensity of LBP among LBP sufferers.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 4","pages":"964-979"},"PeriodicalIF":3.1,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaccination coverage of primary care providers against seasonal influenza, tetanus, pneumococcal pneumonia and herpes zoster: A cross-sectional study in Greece.","authors":"Panagiota Kalatzi, Antonios K Travlos, Nickos Geladas, Maria Iliadou, Chara Tzavara, Costas Chryssanthopoulos, Alexandros Mihopoulos, Styliani Tziaferi","doi":"10.3934/publichealth.2023061","DOIUrl":"10.3934/publichealth.2023061","url":null,"abstract":"<p><strong>Introduction: </strong>Primary care providers' (PCPs) compliance to self-immunization is important for their protection and the protection of their colleagues and patients and has been associated with the coverage of the general public. In this study, we aim to investigate the vaccination coverage of PCPs.</p><p><strong>Methods: </strong>A questionnaire-based cross-sectional survey was conducted among physicians, nurses and pharmacists employed in public or private primary care settings in Greece. Demographic and occupational characteristics as well as vaccination coverage data for influenza, tetanus, pneumococcal pneumonia and herpes zoster were collected. Statistical significance was set at 0.05.</p><p><strong>Results: </strong>In total, 748 (61.7% response rate) PCPs participated. Vaccination rates were 66.4% (496/747) for influenza (2019/2020 flu season), 62.9% (469/746) for tetanus (10-year Td or Tdap booster dose), 70% (14/20) for pneumococcal pneumonia (≥ 1 dose of PPSV23 or PCV13) and 12.3% (10/81) for herpes zoster. Multiple logistic regression revealed that nurses had significantly lower probability of being vaccinated against influenza [odds ratio (<i>OR</i>) = 0.25; 95% confidence interval (<i>CI</i>) = 0.14-0.45] and pharmacists had significantly lower probability of being vaccinated against both influenza (<i>OR</i> = 0.44; 95% <i>CI</i> = 0.31-0.62) and influenza & tetanus (<i>OR</i> = 0.52; 95% <i>CI</i> = 0.37-0.73) compared to physicians. Older age (>40 years) was an independent risk factor for not receiving a tetanus vaccine (40-49 <i>vs</i>. 19-39; <i>OR</i> = 0.42; 95% <i>CI</i> = 0.28-0.63, over 50 years old <i>vs</i>. 19-39; <i>OR</i> = 0.54; 95% <i>CI</i> = 0.36-0.79).</p><p><strong>Conclusions: </strong>The results revealed suboptimal vaccination rates among health providers who are in the frontline of adult immunization. Individualized and targeted measures to improve their vaccination coverage and indirectly the vaccination coverage of their patients, are therefore required.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 4","pages":"952-963"},"PeriodicalIF":3.3,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress and burnout among Greek critical care nurses during the COVID-19 pandemic.","authors":"Thiresia Sikioti, Afroditi Zartaloudi, Despoina Pappa, Polyxeni Mangoulia, Evangelos C Fradelos, Freideriki Eleni Kourti, Ioannis Koutelekos, Evangelos Dousis, Nikoletta Margari, Areti Stavropoulou, Eleni Evangelou, Chrysoula Dafogianni","doi":"10.3934/publichealth.2023051","DOIUrl":"10.3934/publichealth.2023051","url":null,"abstract":"<p><p>Occupational stress and burnout of health personnel during the COVID-19 pandemic, especially of the nursing population in intensive care units (ICUs), were quite frequent along with negative effects and a direct correlation with the manifestation of many physical, behavioral and psychological symptoms. For the purposes of this research, a quantitative survey was carried out, in which 153 ICU nurses of secondary and tertiary public hospitals in Greece participated. Nurses completed anonymously and voluntarily a special electronic questionnaire about stress, burnout, personal concerns about the pandemic, the consequences of the outbreak and their resilience toward COVID-19 patients' care. Specific validated scales were used in this study. Female nurses felt, to a greater extent than males, work-related burnout, especially patient-related burnout and total burnout. There was a statistically significant negative relationship between the existence of a psychological support group within a hospital and personal burnout. Participants who had experience in caring for SARS-CoV-2 patients had higher mental resilience than those without experience. As the consequences experienced by the health professionals of the reference COVID-19 hospitals were increased, so did mental resilience and stress coping strategies during the pandemic. The COVID-19 outbreak and the conditions configurated in the health system had negative effects on the psycho-emotional state of ICU nurses. The manifestation of anxiety, stress and burnout had a direct correlation with both the work and personal functionality of the nurses and the whole of the healthcare services provided. The early recognition of symptoms and their individualized management are imperative for the protection of the psycho-emotional well-being of nurses.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"1 1","pages":"755-774"},"PeriodicalIF":3.1,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70228587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Is a game really a reason for people to die?\" Sentiment and thematic analysis of Twitter-based discourse on Indonesia soccer stampede.","authors":"Otobo I Ujah, Chukwuemeka E Ogbu, Russell S Kirby","doi":"10.3934/publichealth.2023050","DOIUrl":"10.3934/publichealth.2023050","url":null,"abstract":"<p><p>This study examined discourses related to an Indonesian soccer stadium stampede on 1st October 2022 using comments posted on Twitter. We conducted a lexicon-based sentiment analysis to identify the sentiments and emotions expressed in tweets and performed structural topic modeling to identify latent themes in the discourse. The majority of tweets (87.8%) expressed negative sentiments, while 8.2% and 4.0% of tweets expressed positive and neutral sentiments, respectively. The most common emotion expressed was fear (29.3%), followed by sadness and anger. Of the 19 themes identified, \"Deaths and mortality\" was the most prominent (15.1%), followed by \"family impact\". The negative stampede discourse was related to public concerns such as \"vigil\" and \"calls for bans and suspension,\" while positive discourse focused more on the impact of the stampede. Public health institutions can leverage the volume and rapidity of social media to improve disaster prevention strategies.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"1 1","pages":"739-754"},"PeriodicalIF":3.1,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10764967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70228522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible relationship between the gut leaky syndrome and musculoskeletal injuries: the important role of gut microbiota as indirect modulator.","authors":"Jesús Álvarez-Herms, Adriana González, Francisco Corbi, Iñaki Odriozola, Adrian Odriozola","doi":"10.3934/publichealth.2023049","DOIUrl":"10.3934/publichealth.2023049","url":null,"abstract":"<p><p>This article aims to examine the evidence on the relationship between gut microbiota (GM), leaky gut syndrome and musculoskeletal injuries. Musculoskeletal injuries can significantly impair athletic performance, overall health, and quality of life. Emerging evidence suggests that the state of the gut microbiota and the functional intestinal permeability may contribute to injury recovery. Since 2007, a growing field of research has supported the idea that GM exerts an essential role maintaining intestinal homeostasis and organic and systemic health. Leaky gut syndrome is an acquired condition where the intestinal permeability is impaired, and different bacteria and/or toxins enter in the bloodstream, thereby promoting systemic endotoxemia and chronic low-grade inflammation. This systemic condition could indirectly contribute to increased local musculoskeletal inflammation and chronificate injuries and pain, thereby reducing recovery-time and limiting sport performance. Different strategies, including a healthy diet and the intake of pre/probiotics, may contribute to improving and/or restoring gut health, thereby modulating both systemically as local inflammation and pain. Here, we sought to identify critical factors and potential strategies that could positively improve gut microbiota and intestinal health, and reduce the risk of musculoskeletal injuries and its recovery-time and pain. In conclusion, recent evidences indicate that improving gut health has indirect consequences on the musculoskeletal tissue homeostasis and recovery through the direct modulation of systemic inflammation, the immune response and the nociceptive pain.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"710-738"},"PeriodicalIF":3.1,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body image, emotional intelligence and quality of life in peritoneal dialysis patients.","authors":"Eleni Marki, Ioannis Moisoglou, Stamata Aggelidou, Maria Malliarou, Konstantinos Tsaras, Ioanna V Papathanasiou","doi":"10.3934/publichealth.2023048","DOIUrl":"10.3934/publichealth.2023048","url":null,"abstract":"<p><strong>Background: </strong>End-stage-renal-disease is one of the most common chronic diseases, and peritoneal dialysis constitutes one of the replacement therapies. The aim of this study was to investigate the views of patients on peritoneal dialysis regarding their body image, to assess their quality of life and level of emotional intelligence.</p><p><strong>Methods: </strong>A cross-sectional study was performed with structured questionnaires. The sample of the study was the patients undergoing peritoneal dialysis and monitored by the nephrology clinics of 7 public hospitals in Greece.</p><p><strong>Results: </strong>A total of 102 completed questionnaires were collected and analyzed (68% response rate). The participants showed moderate degree of body-image dysphoria (mean = 1.29, <i>SD</i> = 0.94), moderate levels of emotional intelligence and experienced moderate quality of life. According to the statistical analysis, women reported worse body image (<i>p</i> = 0.013) and university graduates showed higher levels of emotionality (<i>p</i> = 0.016). The correlations between the quality of life questionnaire subscales and demographic characteristics revealed statistically significant relationships between marital status and the Physical Functionality subscale, where unmarried people had a better quality of life in this subscale (<i>p</i> = 0.042) and between postgraduate/doctoral degree holders and the subscale Patient Satisfaction (<i>p</i> = 0.035). Also, statistically significant relationships were found between occupation and the Social Interaction subscale, where those engaged in household activities and were unemployed (<i>p</i> = 0.022) showed better quality of life. Participants living in semi-urban areas had better quality of life on the subscale Burden of Kidney Disease (<i>p</i> = 0.034).</p><p><strong>Conclusion: </strong>ESRD patients on peritoneal dialysis suffer significant limitations related to disease and treatment modality. According to our findings, these affect both their body image as well as their quality of life. Improvement in emotional intelligence is the factor which plays an important mediating role in improving both body image and quality of life in patients on peritoneal dialysis.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"698-709"},"PeriodicalIF":3.1,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring barriers to accessing healthcare services for older indigenous people in the Chittagong Hill Tract, Bangladesh.","authors":"Md Sohrab Hossen, Md Salman Sohel, Gazi Abu Horaira, Md Aminul Haque Laskor, Asia Binta Amanat Sumi, Srima Chowdhury, Sima Aktar, Md Khaled Sifullah, Md Fouad Hossain Sarker","doi":"10.3934/publichealth.2023047","DOIUrl":"10.3934/publichealth.2023047","url":null,"abstract":"<p><p>We aim to investigate the obstacles faced by elderly indigenous individuals in the Chittagong Hill Tracts, Bangladesh when accessing healthcare services. A qualitative research approach was utilized, and data collection was carried out in three distinct regions of the aforementioned area. A total of 30 in-depth, semi-structured interviews and participant observations were conducted to achieve the research objectives. Thematic analysis utilizing both a deductive and inductive approach was employed to analyze the data. The Granheim method and Nvivo-12 software were utilized to process, analyze and code the data. The study's findings indicate that a lack of knowledge about healthcare needs, geographical barriers, poor financial conditions, higher cost of medical services, scarcity of hospitals nearby and communication barriers all contribute to inadequate access to healthcare services. By recognizing the factors that impede access to healthcare services in this region, this study offers valuable insight for policymakers and healthcare providers on how to enhance healthcare services for the indigenous population, especially the elderly. Furthermore, the government can adopt a more efficient approach to include these elderly individuals in various social safety net programs.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"678-697"},"PeriodicalIF":3.1,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health and substance use disorder comorbidities among Medicaid beneficiaries: Associations with opioid use disorder and prescription opioid misuse.","authors":"James A Swartz, Dana Franceschini, Kamryn Scamperle","doi":"10.3934/publichealth.2023046","DOIUrl":"10.3934/publichealth.2023046","url":null,"abstract":"<p><strong>Background: </strong>Medicaid presently insures about one-fourth of the US population and disproportionately insures about 38 % of non-elderly adults with an opioid use disorder (OUD). Owing to Medicaid's prominent role insuring persons with an OUD and that Medicaid coverage includes pharmaceutical benefits, there has been considerable interest in studying potential prescription opioid misuse among Medicaid beneficiaries and identifying subpopulations at higher risk for misuse and possible progression to an OUD.</p><p><strong>Methods: </strong>The study goals were to explore the associations among prescription opioid misuse, OUD, and co-occurring mental health and other substance use disorders (SUD). We analyzed Illinois Medicaid 2018 claims data for 1102479 adult beneficiaries 18 to 64 years of age. Using algorithms based on previous studies, we first determined either the presence or absence of nine SUDS (including OUD), nine mental health disorders and likely prescription opioid misuse. Then, we subdivided the beneficiary sample into five groups: those who were prescribed opioids and evidenced either no, possible, or probable misuse; those evidencing an OUD; and those evidencing no opioid use or misuse.</p><p><strong>Results: </strong>Bivariate analyses, upset plots, and multinomial logistic regressions were used to compare the five subgroups on the prevalence of co-occurring SUDS and mental health disorders. Those with an OUD or with probable prescription opioid misuse had the highest prevalence of most co-occurring conditions with beneficiaries with an OUD the most likely to evidence co-occurring SUDS, particularly tobacco use disorder, whereas those with probable misuse had elevated prevalence rates of co-occurring mental health disorders comparable to those with an OUD.</p><p><strong>Conclusion: </strong>The medical complexity of persons with an OUD or misusing prescription opioids are considered in light of recent attempts to expand buprenorphine provision as a medication for OUD among Medicaid beneficiaries. Additionally, we consider the possibility of gender, co-occurring mental health disorders, and tobacco use disorder as important risk factors for progressing to prescription opioid misuse and an OUD.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"658-677"},"PeriodicalIF":3.1,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a web-based education for community mental health case managers on physical healthcare for clients with severe mental illness.","authors":"Jungsu Lee, Yun-Jung Choi","doi":"10.3934/publichealth.2023045","DOIUrl":"10.3934/publichealth.2023045","url":null,"abstract":"<p><p>This study aimed to develop and verify the effects of a web-based physical healthcare education program for community mental health case managers during the time of COVID-19. Six modules of mental health case management physical health education program were developed and provided using the EdWith education platform, which enables real-time streaming, lecture participant management and whether participants have watched the video and watch time. A total of 51 community mental health case managers participated in the study. Collected data were analyzed using SPSS 26.0 software. Participants of the physical healthcare education program testified increased performance in, as well as enhanced attitudes toward physical healthcare. Their confidence in physical healthcare increased significantly from that of the individuals in the control group. The web-based educational program for mental health case managers in physical healthcare may be beneficial to improving the physical health of clients with chronic mental illness.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"647-657"},"PeriodicalIF":3.1,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial infections as potential risk factors for lung cancer: Investigating the role of human papillomavirus and chlamydia pneumoniae.","authors":"Emmanuel Kwateng Drokow, Clement Yaw Effah, Clement Agboyibor, Jemima Twumwaah Budu, Francisca Arboh, Priscilla Akyaa Kyei-Baffour, Yao Xiao, Fan Zhang, Irene Xy Wu","doi":"10.3934/publichealth.2023044","DOIUrl":"10.3934/publichealth.2023044","url":null,"abstract":"<p><strong>Background: </strong>Lung cancer is the leading cause of cancer morbidity and mortality worldwide. Apart from tobacco smoke and dietary factors, microbial infections have been reported as the third leading cause of cancers globally. Deciphering the association between microbiome and lung cancer will provide potential biomarkers and novel insight in lung cancer progression. In this current study, we performed a meta-analysis to decipher the possible association between <i>C. pneumoniae</i> and human papillomavirus (HPV) and the risk of lung cancer.</p><p><strong>Methods: </strong>Literature search was conducted in most English and Chinese databases. Data were analyzed using CMA v.3.0 and RevMan v.5.3 software (Cochrane-Mantel-Haenszel method) by random-effects (DerSimonian and Laird) model.</p><p><strong>Results: </strong>The overall pooled estimates for HPV studies revealed that HPV infections in patients with lung cancer were significantly higher than those in the control group (<i>OR</i> = 2.33, 95% <i>CI</i> = 1.57-3.37, <i>p</i> < 0.001). Base on subgroup analysis, HPV infection rate was significantly higher in Asians (<i>OR</i> = 6.38, 95% <i>CI</i> = 2.33-17.46, <i>p</i> < 0.001), in tissues (<i>OR</i> = 5.04, 95% <i>CI</i> = 2.27-11.19, <i>p</i> < 0.001) and blood samples (<i>OR</i> = 1.40, 95% <i>CI</i> = 1.02-1.93, <i>p</i> = 0.04) of lung cancer patients but non-significantly lower in males (<i>OR</i> = 0.84, 95% <i>CI</i> = 0.57-1.22, <i>p</i> =0.35) and among lung cancer patients at clinical stage I-II (<i>OR</i> = 0.95, 95% <i>CI</i> = 0.61-1.49, <i>p</i> = 0.82). The overall pooled estimates from <i>C. pneumoniae</i> studies revealed that <i>C. pneumoniae</i> infection is a risk factor among lung cancer patients who are IgA seropositive (<i>OR</i> = 1.88, 95% <i>CI</i> = 1.30-2.70, <i>p</i> < 0.001) and IgG seropositive (<i>OR</i> = 1.50, 95% <i>CI</i> = 1.10-2.04, <i>p</i> = 0.010). All seronegative IgA (<i>OR</i> = 0.69, 95% <i>CI</i> = 0.42-1.16, <i>p</i> = 0.16) and IgG (<i>OR</i> = 0.66, 95% <i>CI</i> = 0.42-105, <i>p</i> = 0.08) titers are not associative risk factors to lung cancer.</p><p><strong>Conclusions: </strong>Immunoglobulin (IgA) and IgG seropositive titers of <i>C. pneumoniae</i> and lungs infected with HPV types 16 and 18 are potential risk factors associated with lung cancer.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"10 3","pages":"627-646"},"PeriodicalIF":3.1,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}