AIMS Public Health最新文献

{"title":"Safeguarding nurses' mental health: The critical role of psychosocial safety climate in mitigating relational stressors and exhaustion.","authors":"Teresa Galanti, Michela Cortini, Giuseppe Filippo Giudice, Salvatore Zappalà, Ferdinando Toscano","doi":"10.3934/publichealth.2024046","DOIUrl":"https://doi.org/10.3934/publichealth.2024046","url":null,"abstract":"<p><p>Burnout among nurses is a pervasive concern in healthcare, with profound implications for patient care and nurse well-being. While research has highlighted the detrimental effects of burnout on many aspects of nursing, including patient safety and quality of care, the underlying mechanisms driving burnout warrant further investigation. In this cross-sectional study, we surveyed 196 nurses from diverse Italian hospitals using an online questionnaire via Qualtrics. Our findings revealed significant negative correlations between psychological safety climate and both relational stressors and emotional exhaustion. Conversely, relational stressors positively correlated with emotional exhaustion, and a significant negative indirect effect of psychological safety climate was found for emotional exhaustion through relational stressors, emphasizing the pivotal role of psychological safety climate in mitigating nurse burnout. Our study underscores the potential effectiveness of interventions targeting psychological safety climate and relational stressors in alleviating emotional exhaustion and burnout among nurses. Theoretical implications underscore the importance of deepening the role of psychological safety climate in mitigating emotional exhaustion, while practical implications emphasize the need for fostering a positive psychological safety climate and implementing targeted interventions to support nurses' well-being.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"905-917"},"PeriodicalIF":3.1,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in COVID-19 mortality: A large US-based cohort study (2020-2022).","authors":"Samer A Kharroubi, Marwa Diab-El-Harake","doi":"10.3934/publichealth.2024045","DOIUrl":"https://doi.org/10.3934/publichealth.2024045","url":null,"abstract":"<p><strong>Background: </strong>In the present study, we aim to assess the trend in mortality in COVID-19 by time and sex in a large cohort using Datavant's Death Index database. The main objectives of this study are to analyze mortality cases over time, which are categorized by sex and age, and to identify potential reasons for the observed differences.</p><p><strong>Methods: </strong>This is a retrospective cohort containing information on deceased individuals in the United States and Canada (n = 4,384,265). We included adult male and female patients with a clinical diagnosis of COVID-19 (January-December 2022) (ICD-10 code: U07.1). Mortality cases for males and females were presented over a three-year period of COVID-19 pandemic. Sex ratios presenting the change of mortality cases over time was also computed as the number of diagnosed males over female patients. Sex-differences in the mortality rates were illustrated by age groups.</p><p><strong>Results: </strong>In 2020, mortality cases increased to reach up to 200,000 cases per day and fluctuated due to social and/or cultural events in the US. In 2021, mortality cases reached the highest peak over the time period despite the US vaccine rollout due to holiday gatherings during November and December 2021, as well as the spread of a more contagious strain of the virus. In 2022, mortality cases decreased due to widespread vaccinations and a rise in natural immunity following the first Omicron surge. Furthermore, the proportion of COVID-19 cases in males and females remained stable during the pandemic; however, the number of diagnosed male patients markedly increased during the first months of 2022. Gender discrepancies suggest the role of various factors such as occupation, underlying comorbidities, and behavioral and immunological factors.</p><p><strong>Conclusion: </strong>Our study highlights higher mortality rates observed among males, suggesting that several factors may contribute to such differences, including social, behavioral, and biological factors. Our findings highlight the importance of implementing sex-specific treatment approaches in COVID-19 patients.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"886-904"},"PeriodicalIF":3.1,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health and fitness trends in the post-COVID-19 era in the United Arab Emirates: A cross-sectional study.","authors":"Alexios Batrakoulis, Željko Banićević, Ivana Banićević, Ashokan Arumugam, Ivan Marović, Nemanja Krstić, Saša Obradović","doi":"10.3934/publichealth.2024044","DOIUrl":"https://doi.org/10.3934/publichealth.2024044","url":null,"abstract":"<p><p>The health and fitness (H&F) sector is rapidly evolving and appears to be a vibrant space for industry stakeholders with a great potential globally. This observational study aimed to identify the most popular trends related to H&F services in the United Arab Emirates (UAE) for the first time, focused on the industry status after the coronavirus (COVID-19) pandemic, and aimed to detect potential differences with the recent results observed in other countries or regions. Additionally, a chi-square analysis was applied to determine the significant differences between trends and demographics, such as sex, age, experience, and work status. A national online survey was conducted, and applied the methodology of similar international surveys that have been carried out by the American College of Sports Medicine since 2006. In particular, simple random sampling was utilized through an online questionnaire sent to 2771 professionals involved in the UAE's H&F sector. In total, 322 responses were collected with a response rate of 11.6%. The 10 most popular H&F trends in the UAE during the post-COVID-19 era were exercise for weight loss, personal training, traditional strength training, employing certified exercise professionals, boxing, kickboxing, mixed martial arts, youth athletic development, high-intensity interval training, massage, bodyweight training, and wearable technologies. Exercise for weight loss (<i>p</i> = 0.001) and lifestyle medicine (<i>p</i> = 0.032) were more popular among females compared to males, while traditional strength training (<i>p</i> = 0.035) was reported more frequently by males. Going to health clubs and spas (<i>p</i> = 0.001) and practicing yoga (<i>p</i> = 0.011) were more popular trends among middle-aged (36-64 years) respondents compared to young ones (18-34 years). Athletic development (<i>p</i> = 0.042) was more frequently reported by non-practitioners (students) compared to practitioners (part- and full-time employees). The present results are partially in line with those reported in other recent national, regional, and global surveys, which investigated the top H&F trends after the COVID-19 pandemic. Importantly, the main outcomes of this study indicate that the industry stakeholders should focus on in-person H&F services since trends related to technology and digital services are not currently popular nationwide. Moreover, the majority of the top trends were more traditional and rooted activities, which showed that the current status of the H&F sector has established particular training services, programs, and products in the UAE.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"861-885"},"PeriodicalIF":3.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization and perceptions of language assistance services by medical trainees: a pathway to language certification.","authors":"Tucker Avra, Daniel Cordova, Breena Taira, Jesus R Torres","doi":"10.3934/publichealth.2024043","DOIUrl":"https://doi.org/10.3934/publichealth.2024043","url":null,"abstract":"<p><strong>Background: </strong>Access to language assistance is a patient's right under federal law. Despite this, underuse of language services persists.</p><p><strong>Objective: </strong>The aim of this study was to explore the interest in obtaining bilingual certification and to describe perspectives on language services by resident physicians.</p><p><strong>Methods: </strong>Between May and August 2021, we conducted a cross-sectional survey of residents at a public, urban hospital serving mostly patients with limited English proficiency (LEP). We assessed resident perspectives on language services, exposure to language-related trainings, non-English language (NEL) skills, and interest in bilingual certification.</p><p><strong>Results: </strong>A total of 214 residents of 289 completed the survey (a 74% response rate). Of the 95 residents who used their NEL for patient care, 65 (68%) would be interested in bilingual certification. Sixty-nine (33%), 65 (31%), and 95 (45%) residents disagreed or strongly disagreed with being satisfied with the language services available, convenience, and sufficient equipment, respectively. Furthermore, 28 (13%) disagreed or strongly disagreed that they could achieve bi-directional communication with LEP patients.</p><p><strong>Conclusions: </strong>Over a quarter of the residents expressed interest in bilingual certification and were likely to pass the certification exam. Many reported using their own NEL skills without certification and held negative views on services and trainings.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"850-860"},"PeriodicalIF":3.1,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological characteristics of post-traumatic stress symptoms and its influence on length of hospital stay in inpatients with traumatic fractures in Zunyi, China.","authors":"Guojia Qi, Xiu Dai, Xue Wang, Ping Yuan, Xiahong Li, Miao Qi, Xiuli Hu, Xiuquan Shi","doi":"10.3934/publichealth.2024042","DOIUrl":"https://doi.org/10.3934/publichealth.2024042","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the clinical epidemiological characteristics and occurrence of post-traumatic stress symptoms (PTSS) in patients with traumatic fractures, we sought to analyze the factors that influence the prognosis of a length of hospital stay (LOS) and provide valuable insights to prevent PTSS in fracture patients and improve their prognosis.</p><p><strong>Methods: </strong>Inpatients with traumatic fractures were recruited from a third-class comprehensive general hospital in southwest China between November 2019 and October 2020. Case data of traumatic fracture patients were collected, and a questionnaire that included general information and basic fracture details was completed. The post-traumatic stress disorder Self-rating Scale was used to assess PTSS among the fracture inpatients.</p><p><strong>Results: </strong>A total of 204 inpatients who experienced traumatic fractures were included in this study. Falls accounted for the largest proportion of traumatic fractures. A Cox's regression analysis revealed that serious injury [Hazard Ratio (HR) = 2.44, 95% Confidence Interval (<i>CI</i>): 1.33-4.46], critical illness during hospitalization (HR = 1.70, 95% <i>CI</i>: 1.13-2.54), and undergoing two surgeries (HR = 1.87, 95% <i>CI</i>: 1.20-2.93) were risk factors for longer LOS. Among the fracture patients, 30.39% exhibited positive PTSD symptoms, and physical activity during the fracture [<i>Odds Ratio</i> (<i>OR</i>) = 0.63, 95% <i>CI</i>: 0.45-0.88] and increased pain (<i>OR</i> = 3.34, 95% <i>CI</i>: 1.82-6.11) were identified as influencing factors.</p><p><strong>Conclusions: </strong>Given the high detection rate of PTSS following traumatic fractures, it is crucial for relevant departments to implement targeted measures to protect high risk individuals. Furthermore, strengthening the care provided to the patients' physical and mental health is urgently needed to reduce the incidence of PTSS.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"835-849"},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The talk debrief experience: Intervention in prehospital personnel care during the Covid-19 pandemic.","authors":"Olga Malas, Xavier Perez-Cuit, Jordi García-Sicard, Andrés Cuartero, Gemma Cuartero","doi":"10.3934/publichealth.2024041","DOIUrl":"https://doi.org/10.3934/publichealth.2024041","url":null,"abstract":"<p><p>This study focused on the TALK Debrief Experience in the prehospital personnel (<i>n</i> = 1521) of a western Spanish healthcare region during the COVID-19 Pandemic. The study aimed to apply the TALK clinical debriefing intervention to out-of-hospital clinical staff during pandemics; identify their emotions, thoughts, coping strategies, and solution proposals; determine their demands for improving well-being and coping ability; and disseminate valuable knowledge for addressing trauma in similar situations. The study employed a qualitative methodology within a participatory action research (PAR) framework, conducting group discussions (<i>n</i> = 375) and employing the TALK clinical debriefing method as the guiding framework for the sessions. The discussion group meetings were facilitated by psychologists (<i>n</i> = 67) who had received training in this intervention technique. Various emotions were identified during the sessions, including fear of contagion, lack of control and security, work-related stress, and ethical dilemmas. Proposed solutions and coping strategies addressed increased security measures, promotion of social distancing, stress and anxiety management, and clarity in procedures and provision of protective equipment. The study also highlighted additional demands such as the need for clear information, psychological support, and changes in work practices like reducing strenuous shifts. In conclusion, despite study limitations, such as the lack of long-term follow-up, it emphasized the importance of comprehensively addressing well-being and working conditions during health crises.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"819-834"},"PeriodicalIF":3.1,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of nutrition behavior and food intake with overweight and obesity among school-aged children and adolescents in Pakistan: a cross-sectional study.","authors":"Moazzam Tanveer, Ejaz Asghar, Umar Tanveer, Nadeem Roy, Asifa Zeba, Sameer Badri Al-Mhanna, Xiaoran Ma, Alexios Batrakoulis","doi":"10.3934/publichealth.2024040","DOIUrl":"https://doi.org/10.3934/publichealth.2024040","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess the association between nutrition behavior, food intake, being overweight, and obesity among school-aged children and adolescents aged 9 to 17 years. Additionally, it sought to examine how these factors influence being overweight and obese within this population.</p><p><strong>Methods: </strong>A population-based cross-sectional study was conducted with a representative multistage cluster sample of 4200 Pakistani school-aged children and adolescents aged 9 to 17 years from 62 schools across seven random districts in Punjab province, Pakistan. Underweight (BMI < 5th percentile), overweight (85th ≤ BMI < 95th percentile), and obese (95th percentile ≤ BMI) were defined using the US Center for Disease Control (CDC) 2000 criteria, and a Chi-square test utilized for comparison. The Pearson correlation coefficient (r) assessed any correlations, while a linear regression analysis explored the predictive power of Nutrition Behavior/Food Intake factors (independent variables) on body-weight (dependent variable). A logistic regression analysis estimated the simultaneous influence of multiple factors on the dichotomous outcomes, and the 95% confidence intervals (CI) were calculated. The statistical significance level was set at <i>p</i> < 0.05.</p><p><strong>Results: </strong>The study was comprised of 4108 Pakistani school children aged 9 to 17 years (mean age = 13.92 years, 59.3% boys) from 62 schools. Among them, the prevalence of being overweight and obese individuals was 19.4% and 10.7%, respectively. Factors such as skipping breakfast (OR 2.45, 95% CI 1.53-3.93, <i>p</i> < 0.001), consuming vegetables less than once a week (OR 4.12, 95% CI 3.06-5.55, <i>p</i> < 0.001), consuming soft drinks three or more times a week (OR 4.74, 95% CI 3.73-6.04, <i>p</i> < 0.001), and consuming fast food three or more times a week (OR 10.56, 95% CI 8.16-13.67, <i>p</i> < 0.001) were associated with a higher risk of obesity.</p><p><strong>Conclusion: </strong>Being overweight and obese pose significant concerns among school-aged children and adolescents in Pakistan, showing a troubling upward trend. Poor nutrition behaviors, including frequenting fast-food restaurants and low consumption of fruits and vegetables, contribute to these issues. It is imperative to comprehend these risk factors to formulate impactful policies and dietary interventions that target childhood obesity in Pakistan. Identifying vulnerable populations and implementing tailored intervention strategies are essential for public health efforts. While further interventions may be needed to reduce the body mass index (BMI) and manage being overweight and obese, the findings of this study provide valuable insights into addressing these critical health challenges.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"803-818"},"PeriodicalIF":3.1,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explanatory factors of polydrug use in mid-late teens and the relevance of information sources: Correlational and configurational assessment in Tarragona (Spain).","authors":"Jorge de Andrés-Sánchez, Francesc Valls-Fonayet, Anna Sánchez-Aragón, Inma Pastor-Gosálbez, Angel Belzunegui-Eraso","doi":"10.3934/publichealth.2024039","DOIUrl":"https://doi.org/10.3934/publichealth.2024039","url":null,"abstract":"<p><strong>Background: </strong>Substance use among adolescents is a public health problem, and the simultaneous use of multiple substances aggravates this problem. Although the facilitators of specific substance use in adolescents have been widely investigated, polydrug use is a less common topic. Likewise, the role that the origin of the information available to adolescents regarding substance use plays in relation to polydrug use is practically unexplored.</p><p><strong>Objectives: </strong>This work analyzed the relevance of the origin of the information sources available to adolescents regarding substance use, among which we distinguished those that were monitored (or supervised) by public agencies from those that were unmonitored (or unsupervised) in the consumption of more than one substance. As control variables, we considered three individual factors and four environmental factors. The relevance of these sources was analysed from a dual perspective: on the one hand, their statistical relevance was measured, and on the other hand, how they combined with the control variables was analysed to identify risk and risk-free profiles in substance poly-drug use.</p><p><strong>Methods: </strong>This paper utilized a sample of <i>N</i> = 573 adolescents aged ≥17 years. This sample was collected from a survey administered in the spring of 2023. We examined the impact of unmonitored information sources (peers, siblings, and the Internet) and supervised sources (school, parents, and media) on the combined consumption of alcohol, tobacco, and cannabis. Additionally, we took three individual factors (gender, early onset of alcohol, and tobacco use) and four environmental factors (parental control, alcohol, tobacco, and cannabis use among peers) into account as control variables. Initially, we conducted a regression analysis to adjust for the impact of these factors on polydrug use. Subsequently, we employed a fuzzy set qualitative analysis (fsQCA) to investigate how predictor factors combined with the formation of adolescent profiles associated with polydrug consumption and nonconsumption.</p><p><strong>Results: </strong>Unmonitored information sources were associated with a greater incidence of poly consumption, with ORs of 1.703 and p values of 0.004. However, the protective effects of regulated information sources remained ambiguous. Among the variables positively linked with of polydrug use, are female sex (<i>OR</i> = 1.329, <i>p</i> = 0.0076), early alcohol consumption (<i>OR</i> = 4.680, <i>p</i> < 0.0001), and early tobacco consumption (<i>OR</i> = 3.242, <i>p</i> < 0.001) were the most important. Peer drinking (<i>OR</i> = 1.556, <i>p</i> = 0.0187) and peer cannabis use (<i>OR</i> = 1.351, <i>p</i> = 0.0226) were also significantly correlated. The use of the fsQCA made it possible to identify the profiles of adolescents associated to polysubstance use and non-use. The conditions of the configurations that explained use were characterized by an ","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"773-802"},"PeriodicalIF":3.1,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle habit change related to presenteeism change among Japanese employees.","authors":"Momoko Tsuchida, Takafumi Monma, Sakiko Ozawa, Ayako Kikuchi, Fumi Takeda","doi":"10.3934/publichealth.2024037","DOIUrl":"https://doi.org/10.3934/publichealth.2024037","url":null,"abstract":"<p><p>This study aimed to examine the relationship between changes in lifestyle habits and presenteeism change according to sex. This retrospective cohort study was conducted using data from health checkups, the World Health Organization Health and Work Performance Questionnaire (WHO-HPQ) short form, and health insurance claims for 9366 Japanese corporate employees in 2015 and 2016. Changes in 11 lifestyle habits of sleeping, eating, exercise, drinking, and smoking were classified into four patterns by combining lifestyle habits (good/poor): (a) no worsening, (b) worsening, (c) no improvement, and (d) improvement. A multiple regression analysis was conducted for each sex, with changes in the WHO-HPQ score as the objective variable, lifestyle habits change (worsening or improvement) as the explanatory variables, and age, job position, department, diseases, lifestyle habits, and WHO-HPQ score at baseline as adjustment variables. The results showed worsening of good lifestyle habits, such as sleeping, regular exercise, and frequency of drinking in men, while sleeping in women was associated with negative changes in the WHO-HPQ score. On the other hand, the improvement of poor lifestyle habit of sleeping was associated with positive changes in the WHO-HPQ score. These findings suggest that maintaining good lifestyle habits of sleeping for both sexes, and exercising and drinking for men, may be beneficial in maintaining work performance, while improving the poor lifestyle habit of sleeping for women may be beneficial in improving work performance.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"729-746"},"PeriodicalIF":3.1,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nature's weapons: Bioactive compounds as anti-cancer agents.","authors":"Amogh Auti, Madhura Tathode, Maria Michela Marino, Antonio Vitiello, Andrea Ballini, Francesco Miele, Valeria Mazzone, Alessia Ambrosino, Mariarosaria Boccellino","doi":"10.3934/publichealth.2024038","DOIUrl":"https://doi.org/10.3934/publichealth.2024038","url":null,"abstract":"<p><p>Cancer represents a major global health burden, prompting continuous research for effective therapeutic strategies. Natural compounds derived from plants have emerged as potential strategies for preventing cancer and treatment because of their inherent pharmacological properties. This comprehensive review aimed to evaluate the therapeutic potential of five key natural compounds: apigenin, quercetin, piperine, curcumin, and resveratrol in cancer prevention and therapy. By examining their molecular mechanisms and preclinical evidence, this review seeks to elucidate their role as potential adjuvants or stand-alone therapies in cancer management. The exploration of natural compounds as cancer therapeutics offers several advantages, including low toxicity, wide availability, and compatibility with conventional chemotherapeutic agents. We highlighted the current understanding of their anticancer mechanisms and clinical applications for advancing personalized cancer care to improve patient outcomes. We discussed the empirical findings from in vitro, in vivo, and clinical studies reporting biological activity and therapeutic efficacy in antioxidant, immunomodulatory, anti-carcinogenic, and chemo-sensitizing modes. Innovative delivery systems and personalized treatment approaches may further enhance their bioavailability and therapeutic utility in a synergistic approach with chemo- and radiotherapeutic disease management. This review underscores the importance of natural compounds in cancer prevention and treatment, promoting a multidisciplinary approach to the development of innovative therapeutic strategies.</p>","PeriodicalId":45684,"journal":{"name":"AIMS Public Health","volume":"11 3","pages":"747-772"},"PeriodicalIF":3.1,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}