Rehabilitation Research and Practice最新文献

{"title":"Physical Health and Socioeconomic Status in Ambulatory Adults With Bilateral Spastic Cerebral Palsy.","authors":"Maaike M Eken, Nelleke G Langerak, Jacques du Toit, Melanie Saywood, Robert P Lamberts","doi":"10.1155/2024/8368191","DOIUrl":"10.1155/2024/8368191","url":null,"abstract":"<p><p>Socioeconomic status (SES) tends to influence an individual's access to health care. It is commonly assumed that a poorer SES is associated with a weaker physical health status, especially in disadvantaged populations such as people with cerebral palsy (CP). However, to our knowledge, no study has looked at this assumption. Therefore, the aim of this study was to describe and compare the physical health status of ambulant adults with bilateral CP with different SES backgrounds. In addition, the physical health status of the ambulatory adults with CP was compared to well-matched, typically developing adults. Twenty-eight ambulatory adults with CP (gross motor functional classification system Level I/II/III: <i>n</i> = 11/12/5; SES low/middle/high: <i>n</i> = 10/9/9), and 28 matched typically developing adults were recruited for this study. No differences were observed between adults with CP from different SES backgrounds. Differences in physical health status between typically developing adults and ambulatory adults with CP in all SES backgrounds were found in passive range of motion (<i>p</i> < 0.05), muscle strength (<i>p</i> < 0.001), selectivity (<i>p</i> < 0.001), and muscle tone (<i>p</i> < 0.001) and balance (<i>p</i> < 0.05). The main finding of this study is that physical health status did not differ between ambulatory adults with CP from different SES backgrounds. This finding shows that SES does not always directly impact physical health status in ambulatory adults with CP and highlights the importance of an individual approach. Future research should determine the impact of SES on nonambulatory adults with CP.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"8368191"},"PeriodicalIF":1.5,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Physiological Responses to the 6-Minute Walk Test, Timed Up and Go Test, and Treadmill Cardiopulmonary Exercise Test.","authors":"Eduardo S Alves, R Nicole Bellet, Pramod Sharma, Bryce N Balmain, Craig Aitken, Thomas Doering, Leilani Orola, Anita Green, Tatiana Paim, Fergus O'Connor, Norman R Morris","doi":"10.1155/2024/1317817","DOIUrl":"https://doi.org/10.1155/2024/1317817","url":null,"abstract":"<p><p><b>Purpose:</b> To compare physiological responses during a treadmill cardiopulmonary exercise test (CPX), 6-minute walk test (6MWT), and timed up and go test (TUGT) in individuals referred for unexplained breathlessness and symptom limited treadmill exercise testing. <b>Methods:</b> Heart rate (HR), oxygen consumption (V̇O₂), carbon dioxide production (V̇CO₂), respiratory exchange ratio (RER), minute ventilation (V̇_E), systolic blood pressure (SBP), and rating of perceived exertion (RPE) were recorded throughout each test. <b>Results:</b> Each test demonstrated a significant increase (<i>p</i> < 0.01) in the cardiopulmonary (V̇O₂, V̇CO₂ and V̇_E, RPE, SBP, and HR) and perceptual (RPE) responses from rest to end exercise. The increase in cardiopulmonary and perceptual responses was greatest for the CPX with significantly smaller responses demonstrated during the 6MWT (<i>p</i> < 0.01) and even smaller responses for the TUGT (<i>p</i> < 0.01 vs CPX and 6MWT). <b>Conclusion:</b> Not surprisingly, the treadmill CPX results is the greatest physiological response in our group. Despite being of short duration, the TUGT results in an increased physiological response.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"1317817"},"PeriodicalIF":1.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Reality Technology for Physical and Cognitive Function Rehabilitation in People With Multiple Sclerosis.","authors":"MahgolZahra Kamari, Vitor Siqueira, Jemimah Bakare, Emerson Sebastião","doi":"10.1155/2024/2020263","DOIUrl":"10.1155/2024/2020263","url":null,"abstract":"<p><p>Virtual reality (VR) has significantly expanded the possibilities of medical treatment, particularly in the realm of rehabilitation. VR utilizes advanced technologies to create simulated environments that users perceive as analogous to the real world. Researchers have demonstrated that VR can effectively train motor, sensory, and cognitive functions. This manuscript offers a concise review of recent evidence concerning the effects of VR training on key clinical symptoms in people with multiple sclerosis (pwMS), with the aim of highlighting VR's potential as a complementary rehabilitative tool for improving ubiquitous symptoms of multiple sclerosis (MS)-a neurodegenerative, often disabling, disease. In addition to presenting a brief overview of recent literature on VR for pwMS, this narrative review seeks to provide health professionals with a foundational understanding of VR as a rehabilitative tool in MS. Furthermore, it may aid in identifying gaps in the literature and stimulate the development of new hypotheses and theories regarding the use of VR in patients with a neurodegenerative disease.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"2020263"},"PeriodicalIF":1.5,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Categories of the Patient-Specific Functional Scale Activities in Chronic Neck Pain and Their Relationship to the Neck Disability Index.","authors":"Barbara Van Gorp, Joseph Lesnak, Timothy Fleagle, Kyle Hulshizer, Ashley Nielsen-Wise, Lisabeth Kestel, Carol Vance, Kathleen A Sluka","doi":"10.1155/2024/3126892","DOIUrl":"10.1155/2024/3126892","url":null,"abstract":"<p><p><b>Intoduction:</b> Common outcome measures for chronic neck pain are the Patient-Specific Functional Scale (PSFS) and the neck disability index (NDI). The primary aim was to categorize the top-rated, patient-selected functional activity limitations of the PSFS to determine if there were consistent limited functional activities for individuals with chronic neck pain and how these compared to the constructs of activities on the NDI. The secondary aim was to determine the relationship between scores for individuals who completed both the NDI and PSFS. <b>Design:</b> A retrospective review of data extracted from the electronic medical record, EPIC, within two hospital-based outpatient physical therapy clinics within a health care system. <b>Methods:</b> Retrospective analysis was performed on individual's characteristics, self-selected functional activity limitations, and total scores of the PSFS and NDI. Most common categories of self-selected functional activity limitations were developed by practicing physical therapists. These functional activity limitation categories of the PSFS were compared to the activities of the NDI. Mean PSFS total scores were correlated with the NDI total scores with Spearman's test. <b>Results:</b> Participants were individuals with chronic neck pain from January 2013-September 2018 (<i>n</i> = 2283). Movement-based activities accounted for 60.8% of the functional activity limitations of the PSFS with the top functional activity limitations being cervical motion and exercise (32%). The PSFS total score moderately correlated with NDI (<i>r</i> = -0.50, <i>p</i> = <0.01) which may relate to the differences in constructs of the NDI and the top patient-selected PSFS functional activity limitations found in this analysis. <b>Conclusion:</b> The results suggest that individuals with chronic neck pain present with similar categories of self-selected functional activity limitations that differ from activities of the NDI. Additional research is needed to improve outcome measures to capture patient-selected functional activity limitations and an individual's pain experience.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"3126892"},"PeriodicalIF":1.5,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The NewGait Rehabilitative Device Corrects Gait Deviations in Individuals With Foot Drop.","authors":"Ksenia I Ustinova, Joseph E Langenderfer","doi":"10.1155/2024/2751643","DOIUrl":"https://doi.org/10.1155/2024/2751643","url":null,"abstract":"<p><p>The purpose of this quasiexperimental study was to test the effects of wearing the NewGait rehabilitative device on walking abilities in individuals with foot drop. The study involved 16 participants with foot drops caused by stroke (11 participants), multiple sclerosis (one participant), and peripheral neuropathies (four individuals). During a single testing session, participants walked 12 m at their self-selected speed in four experimental conditions: walking without any orthotic device; walking while wearing a regular plastic posterior leaf ankle foot orthosis (AFO); walking with the NewGait device assisting ankle dorsiflexion only; and walking with the NewGait device assisting the hip, knee, and ankle joint motions. Body motions during walking were recorded using a 3D system for motion analysis and analyzed with a set of spatiotemporal and kinematic parameters and a gait decomposition index. The gait decomposition index indicated sagittal interjoint coordination in the three joint pairs (hip-knee, knee-ankle, and hip-ankle) of the paretic (foot drop) leg during walking and was validated in a previous study. Overall, wearing all three orthotic devices improved the gait velocity, ankle dorsiflexion, and foot clearance compared to gait trials in which no assistive devices were used. However, wearing the AFO significantly restricted the plantarflexion range of motion and decreased interjoint coordination as measured by joint decomposition. In contrast, the NewGait device altered the ankle plantarflexion motions but also increased coordinated movement (reduced the decomposition) in most lower-extremity joint pairs and conditions. Therefore, the NewGait rehabilitative device can be considered superior to a regular AFO in correcting gait deviations caused by foot drop.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"2751643"},"PeriodicalIF":1.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Barriers of Clinical Roles Towards Intensive Care Unit Mobility.","authors":"Hassan Y Aljohani, Shahad Alammar, Shoug Alnawmasi, Riham Alfawzan, Nouf Alotaibi, Noora Mumenah, Arwa Alruwaili, Saleh S Algrani, Tareq F Alotaibi, Mobarak K Alqahtani, Mohammed M Alqahtani, Abdullah M Alanazi, Taha Ismaeil, Sarah Almalki, Jassas Alotaibi","doi":"10.1155/2024/5551184","DOIUrl":"https://doi.org/10.1155/2024/5551184","url":null,"abstract":"<p><p><b>Background:</b> There is overwhelming evidence of improved patient outcomes as a result of early mobilization in the intensive care unit (ICU). However, several barriers of ICU mobility remain understated with reference to clinical roles. The purpose of this study is to investigate the perceived barriers of early mobility of critically ill patients among ICU healthcare providers. <b>Methods:</b> In this cross-sectional study, the Mobilization Attitudes and Beliefs Survey (PMABS-ICU) was administered to ICU healthcare providers using an online survey. The study investigated barriers related to knowledge, attitudes, and behaviors regarding ICU mobility practices. These barriers were compared among different ICU clinical roles. <b>Results:</b> The survey yielded a total number of 214 healthcare providers with 41% female and 59% male. Respiratory therapists reported the highest perceived barriers to ICU mobility (M 39, IQR 36, 43) % compared to physical therapists (who reported the lowest barriers), occupational therapists, nurses, and physicians (<i>p</i> ≤ 0.05). ICU healthcare providers' behavior towards ICU mobility such as perceived benefits and safety is ranked as the primary barrier (M 49, IQR 42, 52) %. Professional experience did not significantly vary among all groups. <b>Conclusion:</b> Our findings highlight that ICU healthcare providers' perceptions, including both potential benefits and safety concerns regarding mobility, are significant barriers to implement mobility practices. ICU mobility barriers should be tackled by providing education and training. A focused effort to include RTs and nurses could advance interdisciplinary ICU mobility practice and reduce associated barriers.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"5551184"},"PeriodicalIF":1.5,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Validity of Motor Assessment Scale on Poststroke Discharge Destination.","authors":"Irene Conradsen, Marius Henriksen, Hana Malá Rytter","doi":"10.1155/2024/2914252","DOIUrl":"10.1155/2024/2914252","url":null,"abstract":"<p><p><b>Background:</b> Stroke frequently leads to hospital admission and subsequent rehabilitation in order to overcome poststroke sequelae, such as motor impairments. Efficient planning of the steps following hospital admission includes early prediction of whether the patient can be discharged home or not. Early assessment of motor performance in patients with stroke-induced motor deficits may be able to function as a predictor of discharge destination but is less explored. <b>Objective:</b> The primary objective was to assess the predictive validity of the Motor Assessment Scale (MAS) on discharge destination both regarding total score and regarding subscores (transfer-mobility items and upper extremity items). <b>Design:</b> The study was designed as a prospective cohort study. <b>Subjects:</b> Thirty-seven consecutively recruited patients with stroke are the subjects of the study. <b>Methods:</b> Logistic regression model was used to calculate the odds of being discharged to own home upon hospital admittance. The predictive ability was examined with a receiving operator characteristic (ROC) curve, and cut-points from the curve were employed in Cox regression. <b>Results:</b> A one-unit higher score on the total MAS significantly increased the odds of being discharged home upon hospital admittance (odds ratio (OR) 1.14, 95% CI 1.04-1.25). The same pattern was observed with the summed items of 1-5 and 6-8. The total MAS showed sensitivity of 91.7% and specificity of 68.0%. Patients having a total MAS score ≥ 24 were 17 times more likely to be discharged home (HR 17.64, 95% CI 2.23-139.57) compared to patients with a lower score. <b>Conclusion:</b> Motor function measured by the MAS can be applied as a predictor of discharge destination upon hospital admission after stroke in Danish setting.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"2914252"},"PeriodicalIF":1.5,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11283334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise-Induced Functional Changes in People with Parkinson's Disease following External Cueing and Task-Based Intervention.","authors":"Christine M Clarkin, Christie L Ward-Ritacco, Leslie Mahler","doi":"10.1155/2024/6188546","DOIUrl":"10.1155/2024/6188546","url":null,"abstract":"<p><strong>Introduction: </strong>The purpose of this study was to evaluate change in motor function, gait speed, dynamic balance, balance confidence, and quality of life (QoL) in nine participants with Parkinson's disease (PwPD) completing Lee Silverman Voice Treatment BIG (LSVT-BIG), an external cueing and task-based intervention. Although supported as an efficacious treatment in PwPD, there is limited research examining clinically meaningful change in outcome measures related to external cueing and task-based interventions.</p><p><strong>Materials and methods: </strong>This was a case series of nine PwPD (age range 64-76 years, 55% male) who completed the LSVT-BIG protocol. Disease duration ranged from 1 to 17 years and was classified as moderate in all participants (Hoehn and Yahr = 2 or 3). Outcome measures included motor function (MDS-UPDRS Part III Motor), gait speed, dynamic balance (MiniBEST), Activities-specific Balance Confidence (ABC), and Summary Index for PD Quality of Life 39 (PDQ-SI). Assessments were completed at baseline (BASE), end of treatment (EOT), and 4 weeks after EOT (EOT+4).</p><p><strong>Results: </strong>Minimal detectable change (MDC) or minimal clinical important difference (MCID) was observed in one or more outcome measures in 8 of 9 participants at EOT and EOT+4 across domains of motor function (67%, 78%), gait speed (78%, 67%), balance confidence (44%, 33%), quality of life (44%, 78%), and dynamic balance (22%, 22%). <i>Discussion</i>. In this case series, 8 of 9 participants showed MDC or MCID changes across multiple functional domains. Improvements were observed immediately post (EOT) and 4-week post-treatment (EOT+4) suggesting a temporal component of the LSVT-BIG impact on functional change. Future research should include clinical trials to examine additional external cueing and task-based intervention efficacy with consideration of intensity, frequency, and mode of delivery across disease severity.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2024 ","pages":"6188546"},"PeriodicalIF":1.5,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10817815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrater Reliability of the Spanish (Colombia) Version of the Post-COVID-19 Functional Status Scale","authors":"Vicente Benavides-Córdoba, Juan Carlos Ávila-Valencia, Diana Guerrero-Jaramillo, Luz Alejandra Lorca, Mauricio Palacios, Rodrigo Torres-Castro, Jhonatan Betancourt-Peña","doi":"10.1155/2023/1124661","DOIUrl":"https://doi.org/10.1155/2023/1124661","url":null,"abstract":"Background. COVID-19 has been one of the most critical public health challenges of recent decades. This disease develops severely in one in five patients, and approximately 5% require admission to a critical care unit. Due to the impact of the sequelae, the Post-COVID-19 Functional Status Scale (PCFS) was developed. This study is aimed at determining the interrater reliability of the Spanish (Colombia) version of the PCFS in adult patients with post-COVID-19 infection. Methods. This is an observational study performed with patients diagnosed with COVID-19. Two evaluators repeated the test-retest of the PCFS scale with knowledge and clinical experience in the care of patients with COVID-19 and had previously applied the test. The PCFS assesses functional limitations at discharge and can be used at 4 and 8 weeks to evaluate practical consequences and determine the degree of disability these patients may have. For interrater reliability, Cronbach’s alpha was applied with its respective confidence interval and the Bland-Altman method. A 95% confidence interval (CI) was taken as the basis for the interpretation of the Intraclass Correlation Coefficient (ICC). Results. A total of 112 adult patients participated in the study, aged <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\"> <mn>51.46</mn> <mo>±</mo> <mn>15.94</mn> </math> years. It was evidenced that the survival, constant care, and activities of daily living questions have an ICC of one (1.000) with an ICC (1.000-1.000), demonstrating excellent reliability, while those close to one were instrumental activities, role participation, symptoms, and final score with an ICC 0.918 to 0.984 and an ICC (0.881-0.989). Thus, a homogeneous distribution of the interrater data was evident. Conclusions. Excellent interobserver reliability of the Spanish (Colombia) version of the PCFS in patients with different degrees of functional status was reported.","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":" 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135192901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Exploration of the Effectiveness of Different Intensity Protocols of Modified Constraint-Induced Therapy in Stroke: A Systematic Review.","authors":"Pavlina Psychouli,&nbsp;Ioannis Mamais,&nbsp;Charalambos Anastasiou","doi":"10.1155/2023/6636987","DOIUrl":"https://doi.org/10.1155/2023/6636987","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the effectiveness of different modified Constraint-Inuced Therapy (mCIMT) protocol intensities on upper extremity motor function in adults with hemiplegia.</p><p><strong>Methods: </strong>A search was conducted in PubMed, Scopus, EBSCO, and Cochrane Library for articles published between April 2010 and December 2021. Only randomized controlled trials (RCTs) were included. Studies were excluded if they used a sample of less than five, mCIMT in combination with other therapy, and/or if they were not written in English. Methodologic quality was assessed using the Cochrane collaboration risk of bias tool-2.</p><p><strong>Results: </strong>Thirty-six RCTs with a total of 721 participants were included. Most researchers followed a moderate to low protocol intensity in terms of total treatment time and moderate to high intensity with regard to restriction time. Almost all of the upper limb motor function measures showed statistically significant improvements (<i>p</i> < .05) after mCIMT, irrespective of the protocol's intensity, but there was lack of high-quality studies. Statistically significant improvements did not always translate to clinical importance.</p><p><strong>Conclusions: </strong>Low-intensity CIMT protocols may result in comparable improvements to more intensive ones but caution has to be taken when drawing conclusions due to high risk of bias studies.</p>","PeriodicalId":45585,"journal":{"name":"Rehabilitation Research and Practice","volume":"2023 ","pages":"6636987"},"PeriodicalIF":1.8,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}