Current Clinical Microbiology Reports最新文献_第9页

Deciphering Fungal Extracellular Vesicles: From Cell Biology to Pathogenesis 解读真菌细胞外囊泡:从细胞生物学到发病机制

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-07-27 DOI: 10.1007/s40588-019-00128-1

Vanessa K. A. Silva, M. Rodrigues, R. May

引用次数: 9

A Rabbit Model for Sheep-Associated Malignant Catarrhal Fever Research: from Virus Infection to Pathogenesis Studies and Vaccine Development 绵羊恶性卡他热兔模型的研究——从病毒感染到发病机制研究及疫苗研制

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-07-17 DOI: 10.1007/s40588-019-00126-3

C. Cunha, D. O'Toole, N. Taus, S. Shringi, D. Knowles, Hong Li

引用次数: 2

Role of Amino Acid Metabolism in the Virulence of Human Pathogenic Fungi 氨基酸代谢在人类病原真菌毒力中的作用

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-07-17 DOI: 10.1007/s40588-019-00124-5

E. Garbe, S. Vylkova

引用次数: 26

Pathogenic Interplay Between Chlamydia trachomatis and Neisseria gonorrhoeae that Influences Management and Control Efforts—More Questions than Answers? 沙眼衣原体和淋病奈瑟菌之间的致病相互作用影响管理和控制的努力-更多的问题比答案?

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-07-12 DOI: 10.1007/s40588-019-00125-4

C. Leonard, R. Schoborg, N. Low, M. Unemo, N. Borel

引用次数: 16

Current Aspects of Diagnosis and Therapeutics of Histoplasmosis and Future Trends: Moving onto a New Immune (Diagnosis and Therapeutic) Era? 组织浆菌病的诊断和治疗的现状和未来趋势:进入一个新的免疫(诊断和治疗)时代?

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-07-03 DOI: 10.1007/s40588-019-00118-3

Fernando Almeida-Silva, D. S. Gonçalves, Marcos de Abreu Almeida, A. Guimarães

引用次数: 6

The complexity of interactions between female sex hormones and Chlamydia trachomatis infections. 女性性激素与沙眼衣原体感染之间相互作用的复杂性。

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-06-01 Epub Date: 2019-05-11 DOI: 10.1007/s40588-019-00116-5

Amy Berry, Jennifer V Hall

{"title":"The complexity of interactions between female sex hormones and Chlamydia trachomatis infections.","authors":"Amy Berry, Jennifer V Hall","doi":"10.1007/s40588-019-00116-5","DOIUrl":"10.1007/s40588-019-00116-5","url":null,"abstract":"Purpose of review: This review focuses specifically on the mechanisms by which female sex hormones, estrogen and progesterone, affect Chlamydia trachomatis infections in vivo and in vitro.Recent findings: Recent data support previous work indicating that estrogen enhances chlamydial development via multiple mechanisms. Progesterone negatively impacts Chlamydia infections also through multiple mechanisms, particularly by altering the immune response. Conflicting data exist regarding the effect of synthetic hormones, such as those found in hormonal contraceptives, on chlamydial infections.Summary: Numerous studies over the years have indicated that female sex hormones affect C. trachomatis infection. However, we still do not have a clear understanding of how these hormones alter Chlamydia disease transmission and progression. The studies reviewed here indicate that there are many variables that determine the outcome of Chlamydia/hormone interactions, including: 1) the specific hormone, 2) hormone concentration, 3) cell type or area of the genital tract, 4) hormone responsiveness of cell lines, and 5) animal models.","PeriodicalId":45506,"journal":{"name":"Current Clinical Microbiology Reports","volume":"6 2","pages":"67-75"},"PeriodicalIF":5.2,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40588-019-00116-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37502299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Toxoplasma: Immunity and Pathogenesis. 弓形虫:免疫和发病机制。

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-03-01 Epub Date: 2019-02-04 DOI: 10.1007/s40588-019-0114-5

Imtiaz A Khan, Charlotte Ouellette, Keer Chen, Magali Moretto

引用次数: 21

Respiratory epithelial cells as master communicators during viral infections. 病毒感染过程中呼吸道上皮细胞作为主要通讯器

IF 4.6

Current Clinical Microbiology Reports Pub Date : 2019-03-01 Epub Date: 2019-02-13 DOI: 10.1007/s40588-019-0111-8

Tanya A Miura

{"title":"Respiratory epithelial cells as master communicators during viral infections.","authors":"Tanya A Miura","doi":"10.1007/s40588-019-0111-8","DOIUrl":"10.1007/s40588-019-0111-8","url":null,"abstract":"Purpose of review: Communication by epithelial cells during respiratory viral infections is critical in orchestrating effective anti-viral responses but also can lead to excessive inflammation. This review will evaluate studies that investigate how respiratory epithelial cells influence the behavior of immune cells and how epithelial cell/immune cell interactions contribute to antiviral responses and immunopathology outcomes.Recent findings: Previous studies have characterized cytokine responses of virus-infected epithelial cells. More recent studies have carefully demonstrated the effects of these cytokines on cellular behaviors within the infected lung. Infected epithelial cells release exosomes that specifically regulate responses of monocytes and neighboring epithelial cells without promoting spread of virus. In contrast, rhinovirus-infected cells induce monocytes to upregulate expression of the viral receptor, promoting spread of the virus to alternate cell types. The precise alteration of PDL expression on infected epithelial cells has been shown to switch between inhibition and activation of antiviral responses.Summary: These studies have more precisely defined the interactions between epithelial and immune cells during viral infections. This level of understanding is critical for the development of novel therapeutic strategies that promote effective antiviral responses or epithelial repair, or inhibit damaging inflammatory responses during severe respiratory viral infections.","PeriodicalId":45506,"journal":{"name":"Current Clinical Microbiology Reports","volume":"6 1","pages":"10-17"},"PeriodicalIF":4.6,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42423445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reovirus: Friend and Foe. 呼肠孤病毒:朋友和敌人。

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-01-01 Epub Date: 2019-07-04 DOI: 10.1007/s40588-019-00121-8

Michael R Eledge, Marcelle Dina Zita, Karl W Boehme

引用次数: 3

Pathogenesis of Human Gammaherpesviruses: Recent Advances. 人类γ疱疹病毒的发病机制：最新进展。

IF 5.2

Current Clinical Microbiology Reports Pub Date : 2019-01-01 Epub Date: 2019-08-01 DOI: 10.1007/s40588-019-00127-2

Darin J Weed, Blossom Damania

引用次数: 0