International Journal of Burns and Trauma最新文献

{"title":"From suspected joint tuberculosis to gouty arthritis: a diagnostic journey.","authors":"Latif Zafar Jilani, Mohammad Istiyak, Arindam Kumar Bhowmik, Akash Sudarsan","doi":"10.62347/PBRZ2450","DOIUrl":"10.62347/PBRZ2450","url":null,"abstract":"<p><p>Gout is a metabolic disorder characterized by hyperuricemia, leading to the deposition of monosodium urate crystals in joints and soft tissues. It commonly affects the first metatarso-phalangeal (MTP) joint, but atypical presentations can pose significant diagnostic challenges. In this report, we describe a rare case of gouty arthritis affecting the proximal interphalangeal (PIP) joint of the second toe, which was initially suspected to be a case of joint tuberculosis. A 38-year-old male presented with a painful swelling over the second toe for two months, with imaging and laboratory findings suggesting an infectious etiology. Despite clinical suspicion of tuberculosis, histopathological examination of the lesion confirmed the presence of amorphous eosinophilic material with chronic inflammatory infiltrate and giant cell reaction, indicative of gout. Subsequent serum uric acid evaluation revealed hyperuricemia, leading to a definitive diagnosis. The patient underwent surgical evacuation of the tophaceous deposits followed by medical management with colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs), and allopurinol. Postoperative follow-up demonstrated complete resolution of symptoms with no recurrence. Aim of the study: This case report aims to highlight the diagnostic challenges of atypical gout presentations, particularly when mimicking infectious conditions such as tuberculosis. It underscores the importance of maintaining a broad differential diagnosis, utilizing histopathology for confirmation, and considering gout even in uncommon anatomical locations.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 4","pages":"171-176"},"PeriodicalIF":1.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconstruction of nose defects using external temporoparietal fascia prefabricated forehead flap - an innovative surgical approach.","authors":"Huili Wang, Ning Liu, Xiaodong Ni, Yufeng Liu","doi":"10.62347/XTYV9971","DOIUrl":"10.62347/XTYV9971","url":null,"abstract":"<p><p>Nasal reconstruction remains one of the most complex challenges in reconstructive plastic surgery due to its intricate three-dimensional architecture and functional demands. While the forehead flap has emerged as the gold standard for nasal reconstruction, conventional techniques inevitably produce conspicuous longitudinal forehead scarring at the pedicle site. We present an innovative approach combining external temporoparietal fascia prefabrication (E-TPFF) with tissue expansion technology to address these limitations. This article aims to enhance the existing method to meet the demand for nasal defect repair while eliminating the operation's drawbacks. Our modified technique offers three significant advantages: (i) complete elimination of visible forehead scarring through an external temporoparietal fascia prefabricated forehead flap (E-TPFF); (ii) providing a flap with reliable vascular supply through temporoparietal fascia prefabrication, and (iii) generation of sufficient flap volume and pedicle length to accommodate even extensive maxillofacial defects. Preliminary results demonstrate that the E-TPFF technique maintains all benefits of traditional forehead flaps while overcoming their most notable aesthetic drawbacks, representing a substantial advancement in facial reconstructive surgery.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 4","pages":"177-182"},"PeriodicalIF":1.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short versus long proximal femoral nail anti-rotation-II (PFNA-II) in the management of unstable intertrochanteric fractures.","authors":"Latif Zafar Jilani, Mohd Saleh, Mohammad Baqar Abbas, Sohail Ahmad, Abdul Qayyum Khan, Asad Khan","doi":"10.62347/LRTZ6852","DOIUrl":"10.62347/LRTZ6852","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;Unstable intertrochanteric (IT) fractures, particularly in elderly patients with low bone mineral density, pose significant treatment challenges. Proximal femoral nail anti-rotation-II (PFNA-II) is widely used, but the optimal implant length (short vs. long) remains debated. The objective of this study was to compare the clinical and functional outcomes of short versus long PFNA-II implants in unstable IT fractures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A prospective comparative study was conducted at a tertiary hospital from November 2018 to November 2020. Adult patients (age ≥18) with recent (≤3 weeks) unstable IT femur fractures were included. Unstable fractures were defined by comminution of the posteromedial cortex, a compromised lateral wall (including reverse obliquity), or subtrochanteric extension. Patients with pathological fractures (other than osteoporosis), open fractures, polytrauma, pre-existing ipsilateral hip pathology, or non-ambulatory status were excluded. Patients were allocated to short PFNA-II (n=38) or long PFNA-II (n=40) groups based on the surgeon's intraoperative judgment (no randomization). All patients underwent standard reduction on a fracture table and fixation with PFNA-II. Postoperative mobilization and weight-bearing protocols were adjusted according to fracture stability and fixation quality. Outcome measures included fracture union time, complications, and the Harris Hip Score (HHS). Statistical significance was set at P&lt;0.05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both groups had similar demographics, fracture types, and surgical durations (P&gt;0.05). Fracture union was achieved in 94.7% (36/38) of short-nail patients and 90% (36/40) of long-nail patients, with no significant difference in union rates or time to union (mean ~14 weeks, P&gt;0.05). The short PFNA-II group demonstrated a significantly higher final HHS (87.2±7.1 vs. 82.3±7.8, P=0.03), with 89.5% achieving good/excellent outcomes vs. 62.5% in the long-nail group. Postoperative complications differed in pattern: anterior thigh pain was more frequent in short nails (15.8% vs. 2.5%), whereas mechanical complications (varus collapse &gt;5°, helical blade lateral migration) were more common in long nails (15% vs. 5.3% varus collapse; 10% vs. 2.6% blade migration). However, overall complication rates were not significantly different between groups (P=0.17). No deep infections, implant breakage, or cut-out occurred in either group.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;PFNA-II fixation is effective for unstable IT fractures with high union rates and low major complication rates in both implant groups. Short PFNA-II nails yielded superior functional outcomes and fewer mechanical complications compared to long nails in similar unstable fracture patterns. These findings suggest that implant length plays a crucial role in optimizing patient outcomes. In most cases of unstable IT fractures, a short PFNA-II appears advantageous, though patient anatomy (","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 4","pages":"159-170"},"PeriodicalIF":1.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toes lateral free flap is an ideal method to repair the soft tissue defect of the finger: a single-center retrospective efficacy evaluation of 106 patients.","authors":"Kelie Wang, Bingxi Lei","doi":"10.62347/YPKY1788","DOIUrl":"10.62347/YPKY1788","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical efficacy of transverse wrist crease perforator flap, the retrograde island flap of proper digital artery, the nutrient vascular fascial pedicled skin flap and the toes lateral free flap in the repair of finger soft tissue defects.</p><p><strong>Methods: </strong>We reviewed the data of 106 patients with finger soft tissue defects who were admitted to Longgang District Orthopedic Hospital from January 2017 to December 2020. The patients were divided into four groups based on the treatment method: Group A (transverse wrist crease perforator flap repair group, N = 27), Group B (retrograde island flap of proper digital artery repair group, N = 23), Group C (nutrient vascular fascial pedicled skin flap repair group, N = 26) and Group D (toes lateral free flap repair group, N = 30). There was no significant difference in sex ratio, age, cause of injury, time of injury and area of defect between the four groups (<i>P</i> > 0.05). We compared the clinical efficacy (including total active motion, two-point discrimination, and cold intolerance), complications, and patient satisfaction.</p><p><strong>Results: </strong>There was no significant difference in wound recovery time among the four groups (<i>P</i> > 0.05), and the evaluation of skin flap recovery, including color, skin temperature, elasticity, and texture, was superior in Group D compared to Groups A, B, and C (<i>P</i> < 0.05). After one month of follow-up, the total active activity of the affected finger was lower in Group A and Group B than in Group C and Group D (<i>P</i> < 0.05), while there was no significant difference in S2-PD (two-point discrimination) among the groups (<i>P</i> > 0.05). The results of the Cold Intolerance Symptom Severity (CISS) scale after one month of follow-up were highest in Group B, followed by Group A, Group C, and then Group D. After six months and one year follow-up, there was no significant difference in the total active activity among the 4 groups (<i>P</i> > 0.05), and the scores of S2-PD and CISS decreased in each group (<i>P</i> < 0.01). Additionally, Group D exhibited better S2-PD and cold tolerance compared to the other three groups. All patients recovered well after surgery, with one case of vascular crisis in Group A, and no complications such as joint stiffness and postoperative infection were observed in any of the groups. The results indicated that group D had the highest satisfaction level (<i>P</i> < 0.01), with no significant difference among Groups A, B, and C.</p><p><strong>Conclusion: </strong>The lateral free flap from the toe is an ideal method for repairing soft tissue defects of the finger, as it effectively restores the finger's shape and skin sensation with minimal complications and a concealed donor site.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 4","pages":"149-158"},"PeriodicalIF":1.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in treating combined posterior hip dislocation and ipsilateral intertrochanteric fracture: a case report.","authors":"Latif Zafar Jilani, Mohammad Istiyak, Syed Mohd Shoaib","doi":"10.62347/LTTR3709","DOIUrl":"10.62347/LTTR3709","url":null,"abstract":"<p><p>The concomitant occurrence of posterior hip dislocation with an ipsilateral intertrochanteric fracture is an exceptionally rare and complex orthopedic injury that poses significant diagnostic and therapeutic challenges. This report presents two cases of this unusual injury pattern, each resulting from high-energy motor vehicle accidents. Patients presented with acute pain and functional impairment of the affected lower limb. Radiographic evaluation confirmed posterior dislocation of the hip associated with an ipsilateral intertrochanteric fracture. Prompt open reduction was necessitated to prevent iatrogenic complications and minimize the risk of avascular necrosis of the femoral head. Definitive fixation of the intertrochanteric fracture was achieved using a Dynamic Hip Screw (DHS) or Dynamic Condylar Screw (DCS), selected based on fracture morphology. Postoperative management focused on staged rehabilitation to optimize recovery. Both patients achieved satisfactory functional outcomes, with Harris Hip Scores of 78 and 82 at one-year follow-up, respectively. The aim of this case report is to present and analyze two rare cases of combined posterior hip dislocation with ipsilateral intertrochanteric fracture, highlighting the diagnostic complexities, surgical challenges and considerations for achieving favorable functional outcomes in the absence of standardized treatment protocols.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 4","pages":"183-189"},"PeriodicalIF":1.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12444418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hip biomechanics, health-related quality of life and walking ability after intramedullary fixation in intertrochanteric fracture: a prospective cohort study.","authors":"Deepak Bandu Ghuge, Sujit Kumar Tripathy, Mantu Jain, Gurudip Das, Shahnawaz Khan, Narayan Prasad Mishra","doi":"10.62347/LHBC5417","DOIUrl":"10.62347/LHBC5417","url":null,"abstract":"<p><strong>Objectives: </strong>Altered hip biomechanics following intertrochanteric fracture fixation can result in impaired mobility, decreased functional outcomes, and a reduced quality of life. Despite achieving optimal reduction and fixation, patients often fail to regain their pre-injury activity levels. This study aims to evaluate how changes in hip biomechanics after intertrochanteric fracture fixation using a proximal femoral nail impact the quality of life.</p><p><strong>Methods: </strong>This prospective cohort study, conducted from July 1, 2020, to June 30, 2022, included individuals aged 18 years and older with isolated intertrochanteric fractures managed using the Proximal Femur Nail Antirotation 2 (PFNA2). Clinical assessments included range of motion, pain levels, abductor strength, the modified Harris Hip Score (HHS), and the Parker and Palmer Mobility Score (PPMS) at 6 weeks, 3 months, and 6 months' post-surgery. Hip biomechanics were evaluated radiographically through parameters such as telescoping, tip-apex distance (TAD), neck-shaft angle, and femoral offset. These findings were correlated with functional scores and health-related quality of life (EQ5D-EuroQol 5 Dimension) score.</p><p><strong>Results: </strong>Out of 47 eligible patients, only 30 could be followed up for six months due to the COVID-19 pandemic, and three patients died in the postoperative period. 25 of 33 patients were over 60 years old. Twenty-nine patients had unstable fractures. All patients had hypovitaminosis D, and 92% of patients had osteoporosis. Fracture union occurred in all cases, with a mean union time of 2.9 ± 0.8 months. Radiographic evaluation showed minimal changes in tip-apex distance and other hip biomechanical parameters (femoral offset, neck shaft angle, telescopy). Functional scores, including modified Harris Hip score and health-related quality of life (HRQOL) measures, improved significantly after surgery. However, at six months, these scores were lower than pre-injury levels. Walking ability varied considerably between age groups (< 60 years' vs > 60 years) at 6 weeks, but abductor strength did not differ significantly in subsequent follow-ups.</p><p><strong>Conclusion: </strong>Poor bone quality, characterized by osteomalacia and osteoporosis, is significantly associated with intertrochanteric fractures in Indian populations. The PFNA 2 nailing system effectively maintains reduction and prevents varus collapse. Functional outcomes and HRQOL improve over time with intramedullary fixation, yet patients seldom return to pre-injury levels, potentially influenced by recall bias.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 3","pages":"92-101"},"PeriodicalIF":1.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in inter observer variation of Schatzker and AO/OTA classification of tibial plateau fractures on addition of CT scan.","authors":"Harpreet Singh Narang, Amit Srivastava, Aditya Nath Aggarwal, Manish Chadha, Anupama Tandon, Sandeep B Rathod","doi":"10.62347/YNVJ5137","DOIUrl":"10.62347/YNVJ5137","url":null,"abstract":"<p><strong>Objective: </strong>Schatzker and AO/OTA classification are commonly used to classify tibial plateau fractures, but they are defined using plain radiographs and may not capture fully the complexity of these fractures. CT scan offers better visualization of occult fractures, joint depression and overall fracture morphology, but its impact on these classifications in term of interobserver variation is unclear. There is paucity of literature on this aspect, hence this study.</p><p><strong>Methods: </strong>A total of 38 cases of tibial plateau fractures were classified by five different observers (four senior residents and one consultant) on the basis of Schatzker and AO/OTA classification. Initially, the observers classified the cases using plain radiographs and then reclassified the cases after supplementing the radiographs with CT scan images. The interobserver reliability was calculated using kappa coefficient.</p><p><strong>Results: </strong>The interobserver agreement for Schatzker classification was found to be moderate on plain radiographs (mean κ_X-ray = 0.593) and substantial after addition of CT scan images (mean κ_{(X-ray + CT scan)} = 0.630). The interobserver agreement for AO/OTA classification was found to be fair on plain radiographs as well as after addition of CT scan images (mean κ_X-ray = 0.313 and mean κ_{(X-ray + CT scan)} = 0.320).</p><p><strong>Conclusion: </strong>After providing advanced imaging both the classification systems showed improvement in the interobserver reliability. However, the change was found to be non-significant. This highlights the weakness of the plain radiograph based classification systems and indicates adoption of classifications based on advanced imaging.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 3","pages":"125-132"},"PeriodicalIF":1.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the success rate of the semi-sitting position compared with the supine position in the emergency intubation of traumatic patients.","authors":"Mohammad Nasr-Esfahani, Amir Reza Hooshmand","doi":"10.62347/ECFH4339","DOIUrl":"10.62347/ECFH4339","url":null,"abstract":"<p><strong>Objectives: </strong>Tracheal intubation (TI) is an essential skill for various healthcare providers, including emergency medicine specialists and anesthesiologists. The ramped position has been hypothesized to facilitate TI. In this study, we assessed the success rate of the semi-sitting position compared with the supine position in emergency intubation.</p><p><strong>Methods: </strong>In this double-blind clinical trial, 162 traumatic patients admitted to the emergency department at Al-Zahra Hospital were randomly assigned to three groups. Patients in Group I underwent TI in the supine position. Patients in Group II underwent TI in a semi-sitting position at a 25-degree angle, while Group III underwent TI in a semi-sitting position at a 35-degree angle. The Cormack-Lehane (C-L) grade and the number of intubation attempts were compared among the groups.</p><p><strong>Results: </strong>Our findings showed a significant reduction in the number of intubation attempts in Groups II and III compared to Group I (P < 0.001). However, the semi-sitting positions (Groups II and III) were associated with a higher incidence of Grade III and IV C-L views, indicating poorer glottic visualization (P < 0.01).</p><p><strong>Conclusions: </strong>The semi-sitting (ramped) position improves the success rate of TI by reducing the number of intubation attempts. However, it significantly worsens glottic visualization, which may pose challenges during airway management. Further studies are needed to optimize patient positioning in emergency intubation.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 3","pages":"143-148"},"PeriodicalIF":1.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative risk of osteoporotic fractures with direct oral anticoagulants versus vitamin K antagonists in atrial fibrillation patients: a systematic review.","authors":"Azad Mojahedi, Abhijeet Singh, Amirhossein Sadeghian, On Chen","doi":"10.62347/JUAO3451","DOIUrl":"10.62347/JUAO3451","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is increasingly prevalent in the elderly population and is associated with an elevated risk of osteoporotic fractures. This systematic review aimed to compare the risk of osteoporotic fractures between direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs), particularly warfarin, in patients with AF and to conduct head-to-head comparisons among different DOACs. We systematically searched literature published between January 2020 and October 2024 across multiple scientific databases. The included studies focused on adult patients with AF taking anticoagulants with fracture outcomes. We extracted and synthesized data on the fracture risk across different anticoagulant types. Our analysis revealed that DOACs, particularly rivaroxaban and apixaban, were associated with a lower fracture risk in AF patients than VKAs. Among the DOACs, apixaban appeared to have the most favorable profile for reducing hip fracture risk. Multiple studies have confirmed that DOACs are associated with decreased vertebral fracture risk compared to warfarin, with risk reductions ranging from 18-32% depending on the specific DOAC. DOACs appear to offer a safer alternative to VKAs in terms of fracture risk in patients with atrial fibrillation. This protective effect may be attributed to their lack of interference with vitamin K-dependent bone metabolism. Although evidence suggests that apixaban and rivaroxaban may have superior bone-protective profiles among DOACs, further research is needed to establish definitive comparisons between individual DOACs and elucidate their protective mechanisms.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 3","pages":"83-91"},"PeriodicalIF":1.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the efficacy of precise platelet-rich plasma injection in grade II meniscus tears.","authors":"Ramin Shayan, Seyyed-Reza Sharifzadeh, Amirhossein Sadeghian, Ehsan Fallah","doi":"10.62347/JZYC7897","DOIUrl":"10.62347/JZYC7897","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the efficacy of precise platelet-rich plasma (PRP) injection, guided by arthroscopy, in patients with grade II meniscus tears.</p><p><strong>Methods: </strong>The study protocol was reviewed and approved by the Institutional Review Board (IRB) of AJA University of Medical Sciences (Code: IR.AJAUMS.REC.1399.258). This study has also been approved by Iranian Registry of Clinical Trials (IRCT) with the code of: IRCT20200217046523N18. In this study, 90 patients with grade II meniscus tears, randomly assigning them to either a PRP injection group (n=45) or a conservative treatment control group (n=45) were enrolled. All patients included in the study had anterior cruciate ligament (ACL) tears and underwent arthroscopic ACL reconstruction. PRP was prepared using a standardized protocol, and injection was performed under arthroscopic guidance using a specialized cannulated loop navigator. Outcomes were assessed using magnetic resonance imaging (MRI) evaluation at baseline, 6, and 12 months post-intervention, and clinical evaluations at the same time points.</p><p><strong>Results: </strong>While the PRP group showed a trend towards improved meniscus tear healing compared to the control group at 6 months (P=0.0552), this difference was not statistically significant at either 6 or 12 months. Similarly, clinical scores showed slight improvements in the PRP group over time, but these differences were not statistically significant compared to baseline or the control group.</p><p><strong>Conclusion: </strong>This study did not demonstrate statistically significant superior outcomes with precise arthroscopically-guided PRP injection as a standalone treatment for grade II meniscus tears compared to conservative management at 6 and 12-month follow-up. Further research with larger sample sizes and longer follow-up periods is needed to definitively assess the role of PRP in the management of grade II meniscus tears.</p>","PeriodicalId":45488,"journal":{"name":"International Journal of Burns and Trauma","volume":"15 3","pages":"133-142"},"PeriodicalIF":1.4,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}