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Clinical Reviews in Bone and Mineral Metabolism最新文献

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Bone Metabolism in SARS-CoV-2 Disease: Possible Osteoimmunology and Gender Implications. SARS-CoV-2 疾病中的骨代谢：可能的骨免疫学和性别影响
IF 0.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2020-01-01 Epub Date: 2020-09-01 DOI: 10.1007/s12018-020-09274-3
Gianmaria Salvio, Claudio Gianfelice, Francesca Firmani, Stefano Lunetti, Giancarlo Balercia, Gilberta Giacchetti
{"title":"Bone Metabolism in SARS-CoV-2 Disease: Possible Osteoimmunology and Gender Implications.","authors":"Gianmaria Salvio, Claudio Gianfelice, Francesca Firmani, Stefano Lunetti, Giancarlo Balercia, Gilberta Giacchetti","doi":"10.1007/s12018-020-09274-3","DOIUrl":"10.1007/s12018-020-09274-3","url":null,"abstract":"<p><p>Even though inflammatory conditions are known to exert adverse effects on bone metabolism, there are no published data regarding SARS-CoV-2 infection and subsequent fracture risk. We present a brief review of the molecular mechanisms linking inflammatory diseases to increased fracture risk/osteoporosis and of the therapeutic strategies that can prevent bone resorption in patients with inflammatory disease, focusing on the RANK-RANKL system. We also make some considerations on gender differences in infection response and on their implications for survival and for the consequences of COVID-19. Several inflammatory cytokines, especially IL-1, IL-6, and TNF-α, stimulate osteoclast activity, favoring bone resorption through the RANK-RANKL system. Data from the previous SARS-CoV outbreak suggest that the present disease also has the potential to act directly on bone resorption units, although confirmation is clearly needed. Even though the available data are limited, the RANK-RANKL system may provide the best therapeutic target to prevent bone resorption after COVID-19 disease. Vitamin D supplementation in case of deficiency could definitely be beneficial for bone metabolism, as well as for the immune system. Supplementation of vitamin D in case of deficiency could be further advantageous. In COVID-19 patients, it would be useful to measure the bone metabolism markers and vitamin D. Targeting the RANK-RANKL system should be a priority, and denosumab could represent a safe and effective choice. In the near future, every effort should be made to investigate the fracture risk after SARS-CoV-2 infection.</p>","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38360919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Health and BMD Research in Pediatric and Adolescent Individuals with ASD: Current Data, Evaluation, and Next Steps 儿童和青少年ASD患者的骨健康和骨密度研究：当前数据、评估和下一步行动
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-11-26 DOI: 10.1007/s12018-019-09268-w
K. Barnhill, Morgan Devlin, L. Hewitson
{"title":"Bone Health and BMD Research in Pediatric and Adolescent Individuals with ASD: Current Data, Evaluation, and Next Steps","authors":"K. Barnhill, Morgan Devlin, L. Hewitson","doi":"10.1007/s12018-019-09268-w","DOIUrl":"https://doi.org/10.1007/s12018-019-09268-w","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09268-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49572069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Bone Metabolism in Inflammatory Bowel Disease and Celiac Disease 炎症性肠病和乳糜泻的骨代谢
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-11-25 DOI: 10.1007/s12018-019-09269-9
C. Valero, Mª José Docampo García
{"title":"Bone Metabolism in Inflammatory Bowel Disease and Celiac Disease","authors":"C. Valero, Mª José Docampo García","doi":"10.1007/s12018-019-09269-9","DOIUrl":"https://doi.org/10.1007/s12018-019-09269-9","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09269-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46883713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Current and Emerging Pharmacotherapy for Gaucher Disease 戈谢病的当前和新兴药物治疗
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-11-20 DOI: 10.1007/s12018-019-09267-x
P. Giraldo
{"title":"Current and Emerging Pharmacotherapy for Gaucher Disease","authors":"P. Giraldo","doi":"10.1007/s12018-019-09267-x","DOIUrl":"https://doi.org/10.1007/s12018-019-09267-x","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09267-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45366003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
X-linked Hypophosphatemic Rickets: the Challenges of Treatment x连锁低磷佝偻病:治疗的挑战
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-10-29 DOI: 10.1007/s12018-019-09266-y
Jessica Sammut, Miriam Giordano Imbroll, Mark Gruppetta
{"title":"X-linked Hypophosphatemic Rickets: the Challenges of Treatment","authors":"Jessica Sammut, Miriam Giordano Imbroll, Mark Gruppetta","doi":"10.1007/s12018-019-09266-y","DOIUrl":"https://doi.org/10.1007/s12018-019-09266-y","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09266-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42003927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skeletal Changes Associated with Osteoarthritis 骨关节炎相关的骨骼变化
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-07-19 DOI: 10.1007/s12018-019-09264-0
N. Mathavan, O. Kennedy
{"title":"Skeletal Changes Associated with Osteoarthritis","authors":"N. Mathavan, O. Kennedy","doi":"10.1007/s12018-019-09264-0","DOIUrl":"https://doi.org/10.1007/s12018-019-09264-0","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09264-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46711908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socio-economic Determinants of Bone Health from Past to Present 从过去到现在骨骼健康的社会经济决定因素
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-07-02 DOI: 10.1007/s12018-019-09263-1
J. Miszkiewicz, Karen M Cooke
{"title":"Socio-economic Determinants of Bone Health from Past to Present","authors":"J. Miszkiewicz, Karen M Cooke","doi":"10.1007/s12018-019-09263-1","DOIUrl":"https://doi.org/10.1007/s12018-019-09263-1","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09263-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41854809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Comparison of Efficacy of Pharmacologic Treatments in Pregnancy- and Lactation-Associated Osteoporosis 妊娠与哺乳期骨质疏松症药物治疗的疗效比较
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-06-15 DOI: 10.1007/s12018-019-09262-2
N. Hong, Y. Rhee
{"title":"Comparison of Efficacy of Pharmacologic Treatments in Pregnancy- and Lactation-Associated Osteoporosis","authors":"N. Hong, Y. Rhee","doi":"10.1007/s12018-019-09262-2","DOIUrl":"https://doi.org/10.1007/s12018-019-09262-2","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09262-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42494136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Osteoporosis in Veterans with Spinal Cord Injury: an Overview of Pathophysiology, Diagnosis, and Treatments 退伍军人脊髓损伤后骨质疏松症的病理生理学、诊断和治疗综述
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-06-01 DOI: 10.1007/s12018-019-09265-z
M. Trbovich, Denny Mack, J. Bruder
{"title":"Osteoporosis in Veterans with Spinal Cord Injury: an Overview of Pathophysiology, Diagnosis, and Treatments","authors":"M. Trbovich, Denny Mack, J. Bruder","doi":"10.1007/s12018-019-09265-z","DOIUrl":"https://doi.org/10.1007/s12018-019-09265-z","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09265-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41486040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Bone Health in the Transgender Population 跨性别人群的骨骼健康
IF 1.8
Clinical Reviews in Bone and Mineral Metabolism Pub Date : 2019-06-01 DOI: 10.1007/s12018-019-09261-3
M. Rothman, Sean J. Iwamoto
{"title":"Bone Health in the Transgender Population","authors":"M. Rothman, Sean J. Iwamoto","doi":"10.1007/s12018-019-09261-3","DOIUrl":"https://doi.org/10.1007/s12018-019-09261-3","url":null,"abstract":"","PeriodicalId":45316,"journal":{"name":"Clinical Reviews in Bone and Mineral Metabolism","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12018-019-09261-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45249378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
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