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Assessment of the Validity and Quality of Polycystic Ovarian Syndrome (PCOS) Screening Tools Available for Women Globally: A Systematic Review. 评估全球妇女可用的多囊卵巢综合征 (PCOS) 筛查工具的有效性和质量:系统回顾。
IF 1.7
Clinics and Practice Pub Date : 2024-08-23 DOI: 10.3390/clinpract14050131
Lea Sacca, Diana Lobaina, Elisheva Knopf, Sara Burgoa, Samantha Jimenez, Goodness Okwaraji, Madison Etzel, Vartiter Vardanyan, Madison Tharp, Meera Rao, Vama Jhumkhawala, Joshua Sohmer, Sebastian Densley, Niko Linzer, Pranav Meka, Daniella Diaz, Michelle Knecht, Dawn Kimberly Hopkins, Panagiota Kitsantas, Maria Mejia, Candy Wilson
{"title":"Assessment of the Validity and Quality of Polycystic Ovarian Syndrome (PCOS) Screening Tools Available for Women Globally: A Systematic Review.","authors":"Lea Sacca, Diana Lobaina, Elisheva Knopf, Sara Burgoa, Samantha Jimenez, Goodness Okwaraji, Madison Etzel, Vartiter Vardanyan, Madison Tharp, Meera Rao, Vama Jhumkhawala, Joshua Sohmer, Sebastian Densley, Niko Linzer, Pranav Meka, Daniella Diaz, Michelle Knecht, Dawn Kimberly Hopkins, Panagiota Kitsantas, Maria Mejia, Candy Wilson","doi":"10.3390/clinpract14050131","DOIUrl":"10.3390/clinpract14050131","url":null,"abstract":"<p><p><b>Background:</b> This systematic review has the following aims: (1) to identify measurement tools used globally by healthcare providers to diagnose PCOS in women at elevated risk; (2) to assess the comprehensiveness of these tools regarding mental health and chronic pain; (3) to list strategies for validating, disseminating, and implementing these tools; and (4) to provide future recommendations for experts in healthcare settings. <b>Methods:</b> This review utilized the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) and the Arksey and O'Malley York methodology. Studies were sourced from the PubMed, Embase, and Cochrane Library databases, with inclusion criteria focusing on peer-reviewed articles addressing PCOS diagnosis and associated comorbidities. Data extraction and analysis followed the Joanna Briggs Institute (JBI) recommendations. <b>Results:</b> A total of 63 studies met the inclusion criteria. Findings indicate that current screening tools for PCOS often lack comprehensive integration of mental health and chronic pain assessments. Tools like the PCOSQ and its updated version, PCOSQ-50, inadequately address pain-related symptoms, highlighting a gap in holistic patient evaluation. This review identified significant associations between PCOS and mental health disorders, including anxiety and depression, emphasizing the need for mental health screenings as part of PCOS management. <b>Conclusions:</b> There is a critical need for validated PCOS screening tools that encompass both physical and psychological aspects of the condition. Educating healthcare providers on the cultural and social determinants influencing PCOS can improve diagnosis and patient outcomes. Future research should focus on developing holistic screening tools and culturally relevant educational resources, aiming to enhance the overall quality of life for women with PCOS.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 5","pages":"1625-1649"},"PeriodicalIF":1.7,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individuals with Tinnitus Report More Positive Experiences following Internet-Based Cognitive Behavioral Therapy. 耳鸣患者在接受基于互联网的认知行为疗法后会有更多积极体验。
IF 1.7
Clinics and Practice Pub Date : 2024-08-21 DOI: 10.3390/clinpract14040130
Vinaya Manchaiah, Eldré W Beukes, Gerhard Andersson, Emily Bateman, De Wet Swanepoel, Kristin Uhler, Vinay
{"title":"Individuals with Tinnitus Report More Positive Experiences following Internet-Based Cognitive Behavioral Therapy.","authors":"Vinaya Manchaiah, Eldré W Beukes, Gerhard Andersson, Emily Bateman, De Wet Swanepoel, Kristin Uhler, Vinay","doi":"10.3390/clinpract14040130","DOIUrl":"10.3390/clinpract14040130","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine whether individuals with chronic tinnitus report more positive experiences following internet-based cognitive behavioral therapy (CBT).</p><p><strong>Methods: </strong>A mixed-methods design was used, nested in clinical trials evaluating internet interventions for tinnitus. Participants (<i>n</i> = 164) completed online questionnaires (both structured and open-ended) providing demographic information as well as health variables (e.g., tinnitus distress, anxiety, depression, insomnia). An open-ended question listing positive effects or outcomes related to having tinnitus was also included. Responses to the open-ended questions were analyzed using qualitative content analysis.</p><p><strong>Results: </strong>Of the 164 eligible participants, 32.3% (<i>n</i> = 53) provided at least 1 positive experience both at pre- and post-intervention, with 9.1% (<i>n</i> = 19) providing positive experiences only at pre-intervention, 49 (29.9%) providing positive experiences only at post-intervention, and 28.7% (<i>n</i> = 47) of the participants did not provide any positive experiences on either measurement occasion. Significantly more positive experiences were reported following the intervention in the overall sample (<i>p</i> < 0.0001, paired sample <i>t</i>-test). In addition, participants who reported positive experiences in both pre- and post-intervention also reported more positive experiences following intervention (<i>p</i> = 0.008, paired sample <i>t</i>-test).</p><p><strong>Conclusions: </strong>Internet-based CBT can help individuals with tinnitus to think more positively by changing unhelpful thought patterns. Open-ended questions can supplement structured questionnaires to measure treatment outcomes.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1615-1624"},"PeriodicalIF":1.7,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Increase in Aspartate Aminotransferase Can Predict Worsening Disease Severity in Japanese Patients with COVID-19. 天冬氨酸氨基转移酶升高可预测日本 COVID-19 患者病情恶化的严重程度
IF 1.7
Clinics and Practice Pub Date : 2024-08-20 DOI: 10.3390/clinpract14040129
Kengo Matsumoto, Tsutomu Nishida, Dai Nakamatsu, Masashi Yamamoto, Koji Fukui, Osamu Morimura, Kinya Abe, Yukiyoshi Okauchi, Hiromi Iwahashi, Masami Inada
{"title":"An Increase in Aspartate Aminotransferase Can Predict Worsening Disease Severity in Japanese Patients with COVID-19.","authors":"Kengo Matsumoto, Tsutomu Nishida, Dai Nakamatsu, Masashi Yamamoto, Koji Fukui, Osamu Morimura, Kinya Abe, Yukiyoshi Okauchi, Hiromi Iwahashi, Masami Inada","doi":"10.3390/clinpract14040129","DOIUrl":"10.3390/clinpract14040129","url":null,"abstract":"<p><strong>Background: </strong>The prognostic significance of liver dysfunction in COVID-19 patients remains unclear. In this study, we investigated the association between liver function test results and severe disease progression in COVID-19 patients.</p><p><strong>Methods: </strong>This retrospective study included consecutive Japanese COVID-19 patients admitted between February 2020 and July 2021. Predictive variables for severe disease progression were identified by multivariate logistic regression analysis. Severe disease-free survival was estimated with the Kaplan-Meier method and Cox regression analysis. Aspartate aminotransferase (AST) was divided into three grades: grade 1, AST < 30 U/L; grade 2, 30 U/L ≤ AST < 60 U/L; and grade 3, AST > 60 U/L.</p><p><strong>Results: </strong>Among 604 symptomatic patients, 141 (23.3%) developed severe disease at a median of 2 days postadmission. The median hospital stay was 10 days, and 43 patients (7.1%) died during hospitalization. Multivariate regression analysis revealed that hypertension, decreased lymphocyte count, and elevated LDH, CRP, and AST levels (grade 2 and grade 3 relative to grade 1) were the significant predictive variables. Severe disease-free survival time was significantly different between the different AST grades (hazard ratio (HR): grade 2 vs. grade 1, 4.07 (95% confidential interval (CI): 2.06-8.03); grade 3 vs. grade 1, 7.66 (95% CI: 3.89-15.1)).</p><p><strong>Conclusions: </strong>The AST level at admission was an independent risk factor for severe disease in hospitalized Japanese patients with COVID-19.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1601-1614"},"PeriodicalIF":1.7,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anterior Hyperfunction Syndrome: Literature Review and Conceptual Model. 前叶功能亢进综合征:文献综述与概念模型。
IF 1.7
Clinics and Practice Pub Date : 2024-08-18 DOI: 10.3390/clinpract14040128
Benjamin Aranda-Herrera, Tania Rubi Agudo-de la Cruz, Carlos Alberto Jurado, Rene Garcia-Contreras
{"title":"Anterior Hyperfunction Syndrome: Literature Review and Conceptual Model.","authors":"Benjamin Aranda-Herrera, Tania Rubi Agudo-de la Cruz, Carlos Alberto Jurado, Rene Garcia-Contreras","doi":"10.3390/clinpract14040128","DOIUrl":"10.3390/clinpract14040128","url":null,"abstract":"<p><p>Combined Kelly syndrome, also known as anterior hyperfunction syndrome, is a complex pathological condition of the stomatognathic system, originally established by five characteristics but primarily triggered by edentulism, specifically, the absence of the upper and posterior mandibular teeth. This condition is characterized by a series of clinical features, such as bone loss, tuberosity growth, enamel wear, periodontal damage, muscle fatigue, pain, and temporomandibular joint issues. However, these features are not unique and rather reflect an oral hyperfunction state. There is a lack of consensus on the best way to assess and diagnose this condition, which is proposed to be understood as an \"oral hyperfunction state\" rather than a syndrome. This study aims to conduct a literature review to analyze the available information on anterior hyperfunction syndrome in dentistry, with the goal of proposing a conceptual model of the etiological risk factors that contribute to early diagnosis and the prevention of complications. This approach has important clinical implications, as it would allow for the early identification and management of risk factors, thus improving the quality of life of patients and preventing malpractice that could compromise their oral health.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1584-1600"},"PeriodicalIF":1.7,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Primary Graft Dysfunction (PGD) Risk Factors in Lung Transplantation (LuTx) Patients. 肺移植 (LuTx) 患者原发性移植物功能障碍 (PGD) 风险因素分析。
IF 1.7
Clinics and Practice Pub Date : 2024-08-15 DOI: 10.3390/clinpract14040127
Michał Jan Kubisa, Małgorzata Edyta Wojtyś, Piotr Lisowski, Dawid Kordykiewicz, Maria Piotrowska, Janusz Wójcik, Jarosław Pieróg, Krzysztof Safranow, Tomasz Grodzki, Bartosz Kubisa
{"title":"Analysis of Primary Graft Dysfunction (PGD) Risk Factors in Lung Transplantation (LuTx) Patients.","authors":"Michał Jan Kubisa, Małgorzata Edyta Wojtyś, Piotr Lisowski, Dawid Kordykiewicz, Maria Piotrowska, Janusz Wójcik, Jarosław Pieróg, Krzysztof Safranow, Tomasz Grodzki, Bartosz Kubisa","doi":"10.3390/clinpract14040127","DOIUrl":"10.3390/clinpract14040127","url":null,"abstract":"<p><strong>Background: </strong>Primary graft dysfunction (PGD) is a form of acute lung injury (ALI) that occurs within 72 h after lung transplantation (LuTx) and is the most common early complication of the procedure. PGD is diagnosed and graded based on the ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen and chest X-ray results. PGD grade 3 increases recipient mortality and the chance of chronic lung allograft dysfunction (CLAD).</p><p><strong>Method: </strong>The aim of this retrospective study was to identify new PGD risk factors. The inclusion criteria were met by 59 patients, who all received transplants at the same center between 2010 and 2018. Donor data were taken from records provided by the Polish National Registry of Transplantation and analyzed in three variants: PGD 1-3 vs. PGD 0, PGD 3 vs. PGD 0 and PGD 3 vs. PGD 0-2.</p><p><strong>Results: </strong>A multiple-factor logistic regression model was used to identify decreasing recipient age; higher donor BMI and higher donor central venous pressure (CVP) for the PGD (of the 1-3 grade) risk factor.</p><p><strong>Conclusions: </strong>Longer cold ischemia time (CIT) and higher donor CVP proved to be independent risk factors of PGD 3.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1571-1583"},"PeriodicalIF":1.7,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Negative Factors Influencing Multiple-Trauma Patients. 影响多重创伤患者的不利因素。
IF 1.7
Clinics and Practice Pub Date : 2024-08-13 DOI: 10.3390/clinpract14040126
Mihaela Anghele, Virginia Marina, Aurelian-Dumitrache Anghele, Cosmina-Alina Moscu, Liliana Dragomir
{"title":"Negative Factors Influencing Multiple-Trauma Patients.","authors":"Mihaela Anghele, Virginia Marina, Aurelian-Dumitrache Anghele, Cosmina-Alina Moscu, Liliana Dragomir","doi":"10.3390/clinpract14040126","DOIUrl":"10.3390/clinpract14040126","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to assess the impact and predicted outcomes of patients with multiple trauma by identifying the prevalence of trauma sustained and associated complications.</p><p><strong>Materials and methods: </strong>This retrospective cohort study focused on individual characteristics of patients with multiple trauma admitted to our County Emergency Hospital. The final table centralized the characteristics of 352 subjects aged between 3 and 93 years who presented with multiple trauma from 2015 to 2021. Inclusion criteria for this study were the presence of multiple trauma, intervention times, mentioned subjects' ages, and types of multiple trauma.</p><p><strong>Results: </strong>Patients with multiple trauma face an increased risk of mortality due to the underlying pathophysiological response. Factors that can influence the outcomes of multiple-trauma patients include the severity of the initial injury, the number of injuries sustained, and the location of injuries.</p><p><strong>Conclusion: </strong>The first 60 min after trauma, known as the \"golden hour,\" is crucial in determining patient outcomes. Injuries to the head, neck, and spine are particularly serious and can result in life-threatening complications.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1562-1570"},"PeriodicalIF":1.7,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and Mortality Life-Attributable Risks for Patients Subjected to Recurrent CT Examinations and Cumulative Effective Dose Exceeding 100 mSv. 反复 CT 检查和累积有效剂量超过 100 mSv 的患者的发病率和死亡率生命归属风险。
IF 1.7
Clinics and Practice Pub Date : 2024-08-10 DOI: 10.3390/clinpract14040125
Entesar Z Dalah, Ahmed B Mohamed, Usama M Al Bastaki, Sabaa A Khan
{"title":"Incidence and Mortality Life-Attributable Risks for Patients Subjected to Recurrent CT Examinations and Cumulative Effective Dose Exceeding 100 mSv.","authors":"Entesar Z Dalah, Ahmed B Mohamed, Usama M Al Bastaki, Sabaa A Khan","doi":"10.3390/clinpract14040125","DOIUrl":"10.3390/clinpract14040125","url":null,"abstract":"<p><p>Computed tomography (CT) multi-detector array has been heavily utilized over the past decade. While transforming an individual's diagnosis, the risk of developing pathogenesis as a result remains a concern. The main aim of this institutional cumulative effective dose (CED) review is to highlight the number of adult individuals with a record of CED ≥ 100 mSv over a time span of 5 years. Further, we aim to roughly estimate both incidence and mortality life-attributable risks (LARs) for the shortlisted individuals. CT studies performed over one year, in one dedicated trauma and emergency facility, were retrospectively retrieved and analyzed. Individuals with historical radiological CED ≥ 100 mSv were short-listed. LARs were defined and established based on organ, age and gender. Out of the 4406 CT studies reviewed, 22 individuals were found with CED ≥ 100 mSv. CED varied amongst the short-listed individuals, with the highest CED registered being 223.0 mSv, for a 57-year-old male, cumulated over an average study interval of 46.3 days. The highest median mortality risk was for females, 214 per 100,000 registered for the age group 51-60 years. While certain clinical indications and diseases require close follow-up using radiological examinations, the benefit-to-risk ratio should be carefully considered, particularly when CT is requested.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1550-1561"},"PeriodicalIF":1.7,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11353021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Retinopathy of Prematurity Risk Using Plasma Levels of Insulin-like Growth Factor 1 (IGF1), Tumor Necrosis Factor-Alpha (TNF-Alpha), and Neonatal Parameters. 利用胰岛素样生长因子 1 (IGF1)、肿瘤坏死因子-α (TNF-Alpha) 和新生儿参数的血浆水平预测早产儿视网膜病变风险。
IF 1.7
Clinics and Practice Pub Date : 2024-08-01 DOI: 10.3390/clinpract14040122
Daniela Mariana Cioboata, Oana Cristina Costescu, Aniko Maria Manea, Florina Marinela Doandes, Mihaela Zaharie, Zoran Laurentiu Popa, Sergiu Costescu, Florina Stoica, Marioara Boia
{"title":"Predicting Retinopathy of Prematurity Risk Using Plasma Levels of Insulin-like Growth Factor 1 (IGF1), Tumor Necrosis Factor-Alpha (TNF-Alpha), and Neonatal Parameters.","authors":"Daniela Mariana Cioboata, Oana Cristina Costescu, Aniko Maria Manea, Florina Marinela Doandes, Mihaela Zaharie, Zoran Laurentiu Popa, Sergiu Costescu, Florina Stoica, Marioara Boia","doi":"10.3390/clinpract14040122","DOIUrl":"10.3390/clinpract14040122","url":null,"abstract":"<p><strong>Background/objectives: </strong>Retinopathy of Prematurity (ROP) remains a leading cause of vision impairment in premature infants, especially those with Respiratory Distress Syndrome (RDS) necessitating respiratory support. This study aimed to identify correlations between plasma levels of Insulin-like Growth Factor 1 (IGF1) and Tumor Necrosis Factor-alpha (TNF-alpha), and the risk of developing ROP. Additionally, it explored the association of ROP severity grades with plasma levels of glucose, lactate dehydrogenase (LDH), creatin phosphokinase (CPK), and other biomarkers, aiming to uncover predictive markers for ROP risk and severity in this population.</p><p><strong>Methods: </strong>This prospective study included premature neonates admitted with RDS requiring respiratory support, conducted over 18 months at the Neonatal Intensive Care Unit of the Louis Turcanu Emergency Clinical Hospital for Children, Timisoara. Plasma levels of IGF1 and TNF-alpha were measured on days 1 and 14 post-birth, alongside the initial assessment of glucose, LDH, and CPK levels.</p><p><strong>Results: </strong>Significant correlations were observed between lower gestational age and elevated LDH levels on day 7-10 (rho = -0.341, <i>p</i> = 0.0123) and between TNF-alpha levels at 2 weeks and ROP severity (rho = 0.512, <i>p</i> = 0.0004). Elevated IGF1 levels were protective against ROP, with Beta coefficients of 0.37 (<i>p</i> = 0.0032) for the first collection and 0.32 (<i>p</i> = 0.0028) for the second, suggesting their potential as biomarkers for ROP risk assessment. Higher levels of TNF-alpha at 2 weeks were associated with an increased risk of ROP (Beta = -0.45, <i>p</i> = 0.0014), whereas higher IGF1 levels offered protective effects against ROP, with Beta coefficients of 0.37 (<i>p</i> = 0.0032) for the first collection and 0.32 (<i>p</i> = 0.0028) for the second. Elevated LDH levels on day 7-10 post-birth were linked to an increased risk of ROP (Beta = 0.29, <i>p</i> = 0.0214).</p><p><strong>Conclusions: </strong>These findings highlight the potential of IGF1 and TNF-alpha as predictive biomarkers for ROP, offering avenues for early intervention and improved management strategies in this high-risk group.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1515-1528"},"PeriodicalIF":1.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11353236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging Generative Artificial Intelligence Models in Patient Education on Inferior Vena Cava Filters. 在下腔静脉滤器患者教育中利用人工智能生成模型。
IF 1.7
Clinics and Practice Pub Date : 2024-07-30 DOI: 10.3390/clinpract14040121
Som P Singh, Aleena Jamal, Farah Qureshi, Rohma Zaidi, Fawad Qureshi
{"title":"Leveraging Generative Artificial Intelligence Models in Patient Education on Inferior Vena Cava Filters.","authors":"Som P Singh, Aleena Jamal, Farah Qureshi, Rohma Zaidi, Fawad Qureshi","doi":"10.3390/clinpract14040121","DOIUrl":"10.3390/clinpract14040121","url":null,"abstract":"<p><p><b>Background</b>: Inferior Vena Cava (IVC) filters have become an advantageous treatment modality for patients with venous thromboembolism. As the use of these filters continues to grow, it is imperative for providers to appropriately educate patients in a comprehensive yet understandable manner. Likewise, generative artificial intelligence models are a growing tool in patient education, but there is little understanding of the readability of these tools on IVC filters. <b>Methods</b>: This study aimed to determine the Flesch Reading Ease (FRE), Flesch-Kincaid, and Gunning Fog readability of IVC Filter patient educational materials generated by these artificial intelligence models. <b>Results</b>: The ChatGPT cohort had the highest mean Gunning Fog score at 17.76 ± 1.62 and the lowest at 11.58 ± 1.55 among the Copilot cohort. The difference between groups for Flesch Reading Ease scores (<i>p</i> = 8.70408 × 10<sup>-8</sup>) was found to be statistically significant albeit with priori power found to be low at 0.392. <b>Conclusions</b>: The results of this study indicate that the answers generated by the Microsoft Copilot cohort offers a greater degree of readability compared to ChatGPT cohort regarding IVC filters. Nevertheless, the mean Flesch-Kincaid readability for both cohorts does not meet the recommended U.S. grade reading levels.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1507-1514"},"PeriodicalIF":1.7,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety Footwear Impact on Workers' Gait and Foot Problems: A Comparative Study. 安全鞋对工人步态和足部问题的影响:比较研究
IF 1.7
Clinics and Practice Pub Date : 2024-07-29 DOI: 10.3390/clinpract14040120
Alberto Arceri, Antonio Mazzotti, Sofia Gaia Liosi, Simone Ottavio Zielli, Elena Artioli, Laura Langone, Francesco Traina, Lorenzo Brognara, Cesare Faldini
{"title":"Safety Footwear Impact on Workers' Gait and Foot Problems: A Comparative Study.","authors":"Alberto Arceri, Antonio Mazzotti, Sofia Gaia Liosi, Simone Ottavio Zielli, Elena Artioli, Laura Langone, Francesco Traina, Lorenzo Brognara, Cesare Faldini","doi":"10.3390/clinpract14040120","DOIUrl":"10.3390/clinpract14040120","url":null,"abstract":"<p><strong>Background: </strong>In this study, we hypothesized that safety footwear (SF) impacts gait patterns, potentially contributing to the podiatric symptoms reported by workers. The purpose of this work was to compare the gait analyses of workers wearing SF and sneakers using inertial sensors while also examining the occurrence of foot problems.</p><p><strong>Methods: </strong>A consecutive cohort of workers from different occupational sectors who wore SF during their work shifts were prospectively assessed through a gait analysis. The gait analysis was conducted under two conditions: first, while wearing SF, and second, while wearing sneakers. In both conditions, inertial sensors were used (Wiva<sup>®</sup> MOB). Participants also underwent a podiatric physical examination to evaluate foot problems.</p><p><strong>Results: </strong>This study shows that SF resulted in a worsening gait pattern compared to sneakers in both genders. The impact was particularly pronounced in female participants, resulting in a significant decline in walking speed and cadence. Discomfort was reported by 83.3% of participants, with a higher prevalence in females (46.6% vs. 36.6%). The SF group exhibited an elevated prevalence of foot problems, with no significant gender variations. It seems that foot problems are more likely to occur when a foot deformity, such as flat or cavus foot or hallux valgus, is present.</p><p><strong>Conclusions: </strong>This study suggests that SF may contribute to the reported podiatric symptoms among workers. Certain footwear characteristics, including weight, mis-fit, and inadequate design, may be factors associated with footwear discomfort and adverse gait patterns, potentially leading to increased foot problems among workers.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1496-1506"},"PeriodicalIF":1.7,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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