Clinics and Practice最新文献

{"title":"Quality in Contemporary Surgical Nursing.","authors":"Georgios Vasilopoulos","doi":"10.3390/clinpract14040096","DOIUrl":"10.3390/clinpract14040096","url":null,"abstract":"<p><p>Quality in healthcare is a multidimensional issue involving various features that depend on service performance and personal assessment (Stavropoulou et al [...].</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1214-1215"},"PeriodicalIF":1.7,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preserving Patient Stories: Bioethical and Legal Implications Related to the Shift from Traditional to Digital Anamnesis.","authors":"Filippo Gibelli, Paolo Bailo, Giuliano Pesel, Giovanna Ricci","doi":"10.3390/clinpract14040095","DOIUrl":"10.3390/clinpract14040095","url":null,"abstract":"<p><p>It is since the beginning of the so-called 'digital revolution' in the 1950s that technological tools have been developed to simplify and optimise traditional, time-consuming, and laborious anamnestic collection for many physicians. In recent years, more and more sophisticated 'automated' anamnestic collection systems have been developed, to the extent that they can actually enter daily clinical practice. This article not only provides a historical overview of the evolution of such tools, but also explores the ethical and medico-legal implications of the transition from traditional to digital anamnesis, including the protection of data confidentiality, the preservation of the communicative effectiveness of the doctor-patient dialogue and the safety of care in patients with poor digital and health literacy.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1196-1213"},"PeriodicalIF":1.7,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individualized Cognitive Functional Therapy Compared with Conservative Treatment for Patients with Chronic Neck Pain-Study Protocol for a Single Blind Pragmatic Randomized Controlled Trial.","authors":"George Ploutarchou, Vasileios Korakakis, Evi Lazoura, Christos Savva, Kyriakos Pavlou, Iacovos Christofi, Katerina Sotiriou, Chara Savvidou, Andreas Panteli, Christos Karagiannis, Ioannis Mamais","doi":"10.3390/clinpract14040098","DOIUrl":"10.3390/clinpract14040098","url":null,"abstract":"<p><p>Chronic neck pain (CNP) is one of the most common musculoskeletal conditions, is considered the second leading cause of pain, and is among the leading causes of disability. Cognitive Functional Therapy (CFT) is a novel behavioral therapy for individualizing the management of spinal pain targeting the multidimensional aspect of musculoskeletal pain. This study outlines the protocol for an assessor-blind randomized controlled trial (RCT) designed to compare an individualized Cognitive Functional Therapy (CFT) intervention with usual care in terms of pain and disability. Aiming for a pragmatic intervention, the CFT group will receive 16 sessions based on patient's condition characteristics, and clinical presentation and progression. The control group will receive 16 sessions of standardized usual care (electrotherapy, massage, posture exercise, and educations). Both groups will have the same intervention duration. Patients will be randomly allocated into groups and will be assessed at baseline, at the 8th session, at the 16th session, and 3 months after randomization. Primary outcomes will be pain, disability, cervical range of motion, and neck muscle isometric strength. To our knowledge, this study will be the first RCT to compare the clinical effectiveness of CFT compared to UC for adults with CNP. The study results will provide information about the use of CFT in clinical practice.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 4","pages":"1225-1233"},"PeriodicalIF":1.7,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11270437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computer-Guided Evaluation of the Use of Two Different Devices in the Reduction of Inferior Tooth Crowding.","authors":"Sara Di Nicolantonio, Maria Ausilia D'Angelo, Davide Pietropaoli, Annalisa Monaco, Eleonora Ortu","doi":"10.3390/clinpract14030094","DOIUrl":"10.3390/clinpract14030094","url":null,"abstract":"<p><strong>Objective: </strong>Lower tooth crowding is considered one of the most common malocclusions in growing patients and due to the potential complications associated with it, it is recommended to intercept this condition as soon as possible. The purpose of this paper is to examine and compare the effectiveness of two different orthodontic devices (elastodontic device and clear aligners) in the treatment of anterior tooth crowding in the jaws of young patients.</p><p><strong>Materials and methods: </strong>Seventy patients aged between 10 and 16 years with anterior inferior tooth crowding were recruited into this study and divided into case and control groups. The former group comprised 35 patients (15 males and 20 females, average age 10.2 years) who were treated with elastodontic devices (EQ CP series, Eptamed), while the control group consisted of 35 patients (15 males and 20 females, average age 10.5 years) who received aligners (Invisalign). All patients underwent periodic visits after 6 months from the start of treatment (T1) and after 1 year (T2) in which the progress of therapy was evaluated by measuring the inferior intercanine distance using a digital caliper. A parametric ANOVA test was conducted for statistical analysis.</p><p><strong>Results: </strong>There is no statistically significant difference between the two groups at either T1 or T2 (<i>p</i> < 0.05), thus making the two treatment modalities comparable.</p><p><strong>Conclusions: </strong>Both elastodontic devices and aligners can be considered as effective tools to successfully conduct inferior expansive treatment for the resolution of tooth crowding; however, the elastodontic devices are considered more comfortable to wear and they are required to be worn for less time during the day.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1185-1195"},"PeriodicalIF":1.7,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia Medication's Impacts on Inflammatory and Neuroendocrine Immune Response in Patients Undergoing Digestive Endoscopy.","authors":"Denisa-Ancuța Popa-Ion, Lidia Boldeanu, Dan-Ionuț Gheonea, Madalina Maria Denicu, Mihail Virgil Boldeanu, Luminița Cristina Chiuțu","doi":"10.3390/clinpract14030093","DOIUrl":"10.3390/clinpract14030093","url":null,"abstract":"<p><p>The aim of this study was to explore the impact of anesthetic drugs currently used to perform lower digestive endoscopy on serum concentrations of inflammation markers and catecholamines. We selected 120 patients and divided them into three lots of 40 patients each: L1, in which no anesthetics were used; L2, in which propofol was used; and L3, in which propofol combined with fentanyl was used. All patients had serum concentrations of adrenaline/epinephrine (EPI), noradrenaline/norepinephrine (NE), tumor necrosis factor alpha (TNF-α), interleukin-4 (IL-4), IL-6, IL-8, and IL-10, taken at three time points: at the beginning of the endoscopic procedure (T₀), 15 min after (T₁), and 2 h after the end of the endoscopic procedure (T₂). The results of the research showed changes in the levels of catecholamines and interleukins (ILs) at T₀, with an increased response in L1 above the mean recorded in L2 and L3 (<i>p</i> < 0.001). At T₁, increased values were recorded in all lots; values were significantly higher in L1. At T₂, the values recorded in L3 were significantly lower than the values in L2 (student T, <i>p</i> < 0.001) and L1, in which the level of these markers continued to increase, reaching double values compared to T₀ (student T, <i>p</i> < 0.001). In L2 at T₁, the dose of propofol correlated much better with NE, EPI, and well-known cytokines. Our results show that propofol combined with fentanyl can significantly inhibit the activation of systemic immune and neuroendocrine response during painless lower digestive endoscopy.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1171-1184"},"PeriodicalIF":1.7,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Orthodontic Needs and Attitudes towards Early Evaluation and Interventions: A Survey-Based Study among Parents of Italian School-Aged Children.","authors":"Federica Di Spirito, Davide Cannatà, Valentina Schettino, Marzio Galdi, Rosaria Bucci, Stefano Martina","doi":"10.3390/clinpract14030092","DOIUrl":"10.3390/clinpract14030092","url":null,"abstract":"<p><p>(1) Background: Parents' awareness of malocclusion and their attitude towards early evaluation and interventions influence children's orthodontic management. This cross-sectional study investigates factors that affect the perceived orthodontic needs and the attitude towards interceptive orthodontics among a sample of one-thousand eight-hundred and six (1806) parents of children aged between 6 and 11 years. (2) Methods: The investigation was carried out thought a 18-items online questionnaire divided as follows: characteristics of respondents; perceived child's orthodontic needs; attitude toward early orthodontic evaluation and interventions. The associations between responses were assessed with a Chi-square test. (3) Results: Two-thirds of the respondents referred to having consulted an orthodontist for their child, and more than half of them initiated the required orthodontic treatment. In 44% of cases, the orthodontic consultation occurred after the age of 7 years. Parents' higher education and history of orthodontic treatment were associated with a greater awareness of orthodontic needs. Parents' perception of the impact of teeth on their child's personality was significantly associated with the decision to start the orthodontic treatment (<i>p</i> < 0.001). (4) Conclusions: Although the parents' level of awareness of their child's orthodontic needs was generally satisfactory, the results of the present study pointed out the need for a better education regarding the importance of an early orthodontic assessment.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1159-1170"},"PeriodicalIF":1.7,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking and Hypertriglyceridemia Predict ST-Segment Elevation Myocardial Infarction in Kosovo Patients with Acute Myocardial Infarction.","authors":"Afrim Poniku, Arlind Batalli, Dua Shita, Zarife Rexhaj, Arlind Ferati, Rita Leka, Artan Bajraktari, Genc Abdyli, Edmond Haliti, Pranvera Ibrahimi, Rona Karahoda, Shpend Elezi, Faik Shatri, Ibadete Bytyçi, Michael Henein, Gani Bajraktari","doi":"10.3390/clinpract14030091","DOIUrl":"10.3390/clinpract14030091","url":null,"abstract":"<p><strong>Background: </strong>Myocardial infarction (MI), presented as ST-segment elevation MI (STEMI) and non-ST-segment elevation MI (NSTEMI), is influenced by atherosclerosis risk factors.</p><p><strong>Aim: </strong>The aim of this study was to assess the patterns of presentation of patients with acute MI in Kosovo.</p><p><strong>Methods: </strong>This was a cross-sectional study conducted at the University Clinical Center of Kosovo, which included all patients hospitalized with acute MI over a period of 7 years.</p><p><strong>Results: </strong>Among the 7353 patients admitted with acute MI (age 63 ± 12 years, 29% female), 59.4% had STEMI and 40.6% had NSTEMI. The patients with NSTEMI patients less (48.3% vs. 54%, <i>p</i> < 0.001), but more of them had diabetes (37.8% vs. 33.6%, <i>p</i> < 0.001), hypertension (69.6% vs. 63%, <i>p</i> < 0.001), frequently had a family history of coronary artery disease (CAD) (40% vs. 38%, <i>p</i> = 0.009), and had more females compared to the patients with STEMI (32% vs. 27%, <i>p</i> < 0.001). The patients with NSTEMI underwent less primary percutaneous interventions compared with the patients with STEMI (43.6% vs. 55.2%, <i>p</i> < 0.001). Smoking [1.277 (1.117-1.459), <i>p</i> ˂ 0.001] and high triglycerides [0.791 (0.714-0.878), <i>p</i> = 0.02] were independent predictors of STEMI.</p><p><strong>Conclusions: </strong>In Kosovo, patients with STEMI are more common than those with NSTEMI, and they were mostly males and more likely to have diabetes, hypertension, and a family history of CAD compared to those with NSTEMI. Smoking and high triglycerides proved to be the strongest predictors of acute STEMI in Kosovo, thus highlighting the urgent need for optimum atherosclerosis risk control and education strategies.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1149-1158"},"PeriodicalIF":1.7,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Modern Diagnostic Procedure-The Introduction of Point-of-Care Ultrasound in Romanian Emergency Physicians' Daily Routine.","authors":"George-Catalin Bouros, Tudor Ovidiu Popa, Paul Lucian Nedelea, Emilian Manolescu, Anca Haisan, Iulia Roca, Petruta Morosanu, Alexandra Hauta, Gabriela Grigorasi, Mihaela Corlade-Andrei, Diana Cimpoesu","doi":"10.3390/clinpract14030090","DOIUrl":"10.3390/clinpract14030090","url":null,"abstract":"<p><strong>Background: </strong>Emergency medicine in Romania has developed fast since inception. The need for faster diagnostic capabilities due to the high workload pre- and in-hospital made point-of-care ultrasound (POCUS) a logical next step. The advantages of POCUS are well known, but implementation presents challenges. Our goal was to study how a straightforward method of implementation would work locally.</p><p><strong>Methods: </strong>Two prospective observational studies were conducted at 6 months (prehospital) and 4 months (in-hospital). The protocol used was extended focused assessment sonography in trauma (eFAST), and the shock index (SI) was used to stratify patients. Voluntary sampling was conducted by emergency physicians. The primary outcomes were patient numbers, type of case use, results, and accuracy.</p><p><strong>Results: </strong>The prehospital study registered 34 patients: 41% traumas, 35% cardiac arrest, 18% shock, and 6% acute respiratory distress. The in-hospital study patients were 78: 36% traumas, 6% cardiac arrests, 41% shock, and 17% acute respiratory distress. A total of 88.5% of the cases were confirmed with definitive imagistic findings.</p><p><strong>Conclusion: </strong>The studies mark an increase in POCUS usage and use in complicated cases. Providing supervision and feedback into clinical practice resulted in a further increase in POCUS usage, the second study having an 88.5% accuracy when compared to the final diagnostic proving the increased efficiency of a longitudinal training approach.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1137-1148"},"PeriodicalIF":1.7,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Screening for Long QT Syndrome and Cardiac Anomalies in Infants: A Comprehensive Study.","authors":"Luana Nosetti, Marco Zaffanello, Carolina Lombardi, Alessandra Gerosa, Giorgio Piacentini, Michele Abramo, Massimo Agosti","doi":"10.3390/clinpract14030082","DOIUrl":"10.3390/clinpract14030082","url":null,"abstract":"<p><p>(1) Background: Sudden Infant Death Syndrome (SIDS) represents sudden and unexplained deaths during the sleep of infants under one year of age, despite thorough investigation. Screening for a prolonged QTc interval, a marker for Long QT Syndrome (LQTS), should be conducted on all newborns to reduce the incidence of SIDS. Neonatal electrocardiograms (ECGs) could identify congenital heart defects (CHDs) early, especially those not detected at birth. Infants with prolonged QTc intervals typically undergo genetic analysis for Long QT Syndrome. (2) Methods: The study involved infants aged 20-40 days, born with no apparent clinical signs of heart disease, with initial ECG screening. Infants with prenatal diagnoses or signs/symptoms of CHDs identified immediately after birth, as well as infants who had previously had an ECG or echocardiogram for other medical reasons, were excluded from the study. We used statistical software (SPSS version 22.0) to analyze the data. (3) Results: Of the 42,200 infants involved, 2245 were enrolled, with 39.9% being males. Following this initial screening, 164 children (37.8% males) with prolonged QTc intervals underwent further evaluation. Out of these 164 children, 27 children were confirmed to have LQTS. However, only 18 children were finally investigated for genetic mutations, and mutations were identified in 11 tests. The most common mutations were <i>LQT1</i> (54.5%), <i>LQT2</i> (36.4%), and <i>LQT3</i> (1 patient). Treatment options included propranolol (39.8%), nadolol (22.2%), inderal (11.1%), metoprolol (11.1%), and no treatment (16.7%). The most common abnormalities were focal right bundle branch block (54.5%), left axis deviation (9.2%), and nonspecific ventricular repolarization abnormalities (7.1%). Multiple anomalies were found in 0.47% of children with focal right bundle branch block. Structural abnormalities were associated with specific features in 267 patients (11.9%), primarily isolated patent foramen ovale (PFO) at 61.4%. (4) Conclusions: This screening approach has demonstrated effectiveness in the early identification of LQTS and other cardiac rhythm anomalies, with additional identification of mutations and/or prolonged QTc intervals in family members. Identifying other ECG abnormalities and congenital heart malformations further enhances the benefits of the screening.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1038-1053"},"PeriodicalIF":1.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11203353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Isotretinoin on Insulin Resistance and Serum Adiponectin Levels in Acne Vulgaris Patients: A Systematic Review and Meta-Analysis.","authors":"Eleni Paschalidou, Georgios Katsaras, Thomas Papoulakis, Evangelia Kalloniati, Dimitrios Kavvadas, Sofia Karachrysafi, Dorothea Kapoukranidou, Georgios Tagarakis, Theodora Papamitsou","doi":"10.3390/clinpract14030081","DOIUrl":"10.3390/clinpract14030081","url":null,"abstract":"<p><strong>Background: </strong>Isotretinoin is the drug of choice for severe acne. We sought to examine the potential link between isotretinoin and insulin resistance.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis in accordance with the PRISMA statement. A comprehensive search of the PubMed/MEDLINE, SCOPUS, and Cochrane databases was performed until 12 January 2022 utilizing the PICO (Patient, Intervention, Comparison, Outcome) tool. Fifteen English-language studies focusing on isotretinoin-treated acne patients were included. Serum levels of insulin, glucose, and adiponectin were evaluated before and after treatment, and insulin sensitivity was assessed using the HOMA-IR. A meta-analysis was conducted using RevMan 5.4.1 software, and a quality assessment was undertaken using the ROBINS-I tool.</p><p><strong>Results: </strong>The meta-analysis unveiled a statistically significant rise in the post-treatment levels of adiponectin, an anti-inflammatory agent, which inhibits liver glucose production while enhancing insulin sensitivity (SMD = 0.86; 95% confidence interval (95% CI) = 0.48-1.25, <i>p</i>-value < 0.0001; I² = 58%). Our subgroup analysis based on study type yielded consistent findings. However, no statistically significant outcomes were observed for insulin, glucose levels, and the HOMA-IR.</p><p><strong>Conclusions: </strong>There is not a clear association between isotretinoin and insulin resistance, but it appears to enhance the serum levels of adiponectin, which participates in glucose metabolism.</p>","PeriodicalId":45306,"journal":{"name":"Clinics and Practice","volume":"14 3","pages":"1021-1037"},"PeriodicalIF":1.7,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11202953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}