Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献_第3页

Unusual immature epignathus teratoma: Case report with survival 不寻常的未成熟附着物畸胎瘤：存活1例报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-03-01 Epub Date: 2025-09-25 DOI: 10.1016/j.ajoms.2025.09.014

Julia Esther Kattan-Rodriguez , Juan José Guifarro , Hugo Romero Alvarenga , Francisco Adolfo Díaz , Fabiola Salgado-Chavarria , Maria Fernanda Cardona , Ingrid Jissela Barahona , Adriana Diaz-Rodríguez , Vilma Alejandra Umanzor Bonilla

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Case of adult unilateral cleft lip and alveolus treated with occlusal reconstruction at alveolar bone graft site following removal of giant surgical ciliated cyst 巨大纤毛囊肿切除后牙槽骨植骨重建治疗成人单侧唇裂牙槽畸形1例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-03-01 Epub Date: 2025-09-03 DOI: 10.1016/j.ajoms.2025.09.004

Kazuhiro Imoto , Shinnosuke Nogami , Nyungkwang Kwon , Hiromitsu Morishima , Keiko Matsui , Hiroyuki Kumamoto , Kensuke Yamauchi

{"title":"Case of adult unilateral cleft lip and alveolus treated with occlusal reconstruction at alveolar bone graft site following removal of giant surgical ciliated cyst","authors":"Kazuhiro Imoto , Shinnosuke Nogami , Nyungkwang Kwon , Hiromitsu Morishima , Keiko Matsui , Hiroyuki Kumamoto , Kensuke Yamauchi","doi":"10.1016/j.ajoms.2025.09.004","DOIUrl":"10.1016/j.ajoms.2025.09.004","url":null,"abstract":"<div><div>A surgical ciliated cyst (SC cyst) is a non-odontogenic lesion that can develop in the maxilla when respiratory (ciliated) epithelium from the maxillary sinus or nasal cavity becomes entrapped in bone during surgery. Although SC cysts most often develop following procedures that breach the maxillary sinus mucosa, they may also occur, though rarely, at an alveolar bone graft site in patients with an alveolar cleft. Reported here is a case of a large SC cyst that formed at an alveolar bone graft site and was then successfully managed with enucleation, particulate cancellous bone and marrow (PCBM) grafting under a custom titanium mesh, and implant placement in the same area, resulting in excellent occlusion. A 31-year-old male was presented with gingival swelling in the anterior maxilla. The patient had undergone PCBM grafting at the age of nine years for a right-side cleft lip and alveolus. CT scanning revealed a sizable cystic lesion (45 × 32 × 28 mm) in the anterior maxilla. A cystectomy including nucleation and PCBM grafting with a titanium mesh was performed, followed by implant placement approximately two years later. No evidence of cyst recurrence or implant failure has been noted more than ten years following the operation.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 2","pages":"Pages 255-261"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Desmoplastic ameloblastoma arising in the maxilla where it was difficult to determine the extent of resection: Significance of MRI diagnosis – A case report and updated literature review 上颌骨发生难以确定切除范围的成釉细胞瘤：MRI诊断的意义- 1例报告及最新文献综述

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-08-10 DOI: 10.1016/j.ajoms.2025.08.003

Satoshi Shimohama , Manabu Yamada , Yuta Yasui , Masafumi Nishikawa , Kenichiro Suga , Seiji Asoda

{"title":"Desmoplastic ameloblastoma arising in the maxilla where it was difficult to determine the extent of resection: Significance of MRI diagnosis – A case report and updated literature review","authors":"Satoshi Shimohama , Manabu Yamada , Yuta Yasui , Masafumi Nishikawa , Kenichiro Suga , Seiji Asoda","doi":"10.1016/j.ajoms.2025.08.003","DOIUrl":"10.1016/j.ajoms.2025.08.003","url":null,"abstract":"<div><div>Desmoplastic ameloblastoma (DA) is a histological subtype of \"Ameloblastoma, conventional”, accounting for approximately 4–13 % of ameloblastoma cases. DA is associated with a high rate of local recurrence due to tumor infiltration into the adjacent healthy bone trabeculae. Additionally, radiographic findings typically demonstrate a mixed image of unclear boundary radiolucency and radiopacity, often complicating determination of the surgical resection margin. We herein report our experience with DA, where determining the extent of resection is difficult, and provide an updated review of the relevant literature. A 62-year-old male who presented to our department for further evaluation and treatment of a left maxillary anterior lesion. Computed tomography (CT) revealed a mixed image of unclear boundary radiolucency and radiopacity from the left maxillary anterior to the premolar region. The molar region showed a clearly demarcated radiolucency. A three-dimensional image analysis of CT showed no continuity between the two lesions, but magnetic resonance imaging (MRI) showed slightly heterogeneous contrast enhancement in both lesions. Biopsy confirmed the diagnosis of DA, and the patient subsequently underwent partial resection of the maxilla, including both lesions. A histopathological examination revealed DA in both lesions, and tumor microinvasion in the normal bone trabeculae connecting them. The surgical margins were negative. The patient is currently 17 months postoperatively with no signs of recurrence and a favorable clinical course. In the case of DA, which exhibits a greater tendency for invasion than conventional ameloblastomas, utilizing various modalities to determine the extent of resection enables appropriate resection, including a safety margin.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 98-107"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145475744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The fundamentals of tissue engineering in the process of alveolar bone regeneration 组织工程在牙槽骨再生过程中的基础

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-07-04 DOI: 10.1016/j.ajoms.2025.07.003

Shiva Shirazian , Naghmeh Bahrami , Jafar Ai , Mohamad Bayat , Abdolreza Mohamadnia , Amin Khajavi , Fatemeh Ghorbani Shemshadsara

{"title":"The fundamentals of tissue engineering in the process of alveolar bone regeneration","authors":"Shiva Shirazian , Naghmeh Bahrami , Jafar Ai , Mohamad Bayat , Abdolreza Mohamadnia , Amin Khajavi , Fatemeh Ghorbani Shemshadsara","doi":"10.1016/j.ajoms.2025.07.003","DOIUrl":"10.1016/j.ajoms.2025.07.003","url":null,"abstract":"<div><div>Bone has a natural self-healing ability through the interaction of osteoblasts and osteoclasts under physiological conditions. However, when defects exceed the critical size due to congenital anomalies, trauma, inflammation, periodontal diseases, tumor resection, or surgical interventions, alveolar bone regeneration becomes challenging. Autologous bone grafting is the gold standard for alveolar bone defects but has drawbacks such as donor site morbidity and infection risks. Allografts also pose challenges, including immune responses and limited bone formation. Tissue engineering presents an alternative, utilizing bioactive scaffolds, osteogenic cells, and growth factors to create a biomimetic environment that enhances regeneration. This review explores the fundamentals of tissue engineering and its application in bone reconstruction. It first discusses the key components of tissue engineering, including cells, scaffolds, and growth factors in bone tissue engineering. This is followed by an overview of their integration with recent advancements in 3D-printed scaffolds for alveolar bone regeneration.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 1-10"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145475829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of a Sialadenoma papilliferum occurred in 80s female 一例罕见的涎腺乳头状瘤发生于80年代的女性

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-07-08 DOI: 10.1016/j.ajoms.2025.07.002

Moe Tominaga, Hirokazu Yutori, Masanori Masui, Suguru Ishida

引用次数: 0

TCR repertoire analysis reveals predominant local clonal expansion of T cells with minimal circulation in oral lichenoid contact lesions TCR曲目分析显示，口腔地衣样物质接触性病变中，主要是局部克隆扩增的T细胞，循环最小

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-08-23 DOI: 10.1016/j.ajoms.2025.08.005

Naoto Nishii , Fumihiko Tsushima , Jinkyo Sakurai , Yuya Su , Naoya Kinoshita , Yu Oikawa , Yosuke Hirotsu , Toshimitsu Ohsako , Emi Furusawa-Nishii , Masao Omata , Hiroyuki Harada

{"title":"TCR repertoire analysis reveals predominant local clonal expansion of T cells with minimal circulation in oral lichenoid contact lesions","authors":"Naoto Nishii , Fumihiko Tsushima , Jinkyo Sakurai , Yuya Su , Naoya Kinoshita , Yu Oikawa , Yosuke Hirotsu , Toshimitsu Ohsako , Emi Furusawa-Nishii , Masao Omata , Hiroyuki Harada","doi":"10.1016/j.ajoms.2025.08.005","DOIUrl":"10.1016/j.ajoms.2025.08.005","url":null,"abstract":"<div><h3>Objective</h3><div>Oral lichenoid contact lesions (OLCLs) are inflammatory oral mucosal disorders triggered by hypersensitivity to dental metals and resemble oral lichen planus (OLP) clinically and histologically. The T-cell receptor (TCR) repertoire in lesions reflects the type and frequency of the antigen; however, the details of the TCR repertoires of OLCLs have never been reported. The aim of this study was to evaluate the presence of clonally expanded T cells within the lesion tissue and peripheral blood of OLCL, and to determine whether differences exist between these compartments.</div></div><div><h3>Methods</h3><div>We analyzed TCR repertoires in lesion tissues from nine OLCL patients and peripheral blood from five of these patients using high-throughput next-generation sequencing. V–J gene usage, and complementarity-determining region 3 clonotypes were examined to detect antigen-driven clonal expansions.</div></div><div><h3>Results</h3><div>All OLCL lesions exhibited clonally expanded T-cell populations, with dominant clones exceeding 1 % frequency. These large expanded clones were predominantly localized within lesion tissues and were either absent or found at very low frequencies in peripheral blood. In one patient, an identical expanded clone was detected in two separate OLCL lesions contacting metal prostheses but was undetectable in blood.</div></div><div><h3>Conclusion</h3><div>Our study demonstrates that OLCL lesions harbor clonally expanded T cells that remain primarily localized within the tissue and are largely absent from peripheral blood. This distribution pattern supports the hypothesis that resident memory T cells responding to metal-related antigens may contribute to disease pathogenesis.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 146-157"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A case of palatal canalicular adenoma 腭小管腺瘤1例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-07-09 DOI: 10.1016/j.ajoms.2025.07.009

Hitomi Kajikawa , Yoshihiro Morita , Kaori Oya , Ryotaro Kakimoto , Sho Katsura , Emiko Ogasa , Yukiko Kitahira , Yuka Matsumiya-Matsumoto , Akinori Takeshita , Narikazu Uzawa

{"title":"A case of palatal canalicular adenoma","authors":"Hitomi Kajikawa , Yoshihiro Morita , Kaori Oya , Ryotaro Kakimoto , Sho Katsura , Emiko Ogasa , Yukiko Kitahira , Yuka Matsumiya-Matsumoto , Akinori Takeshita , Narikazu Uzawa","doi":"10.1016/j.ajoms.2025.07.009","DOIUrl":"10.1016/j.ajoms.2025.07.009","url":null,"abstract":"<div><div>Canalicular adenoma (CA) is a rare, benign salivary gland tumor accounting for less than 1 % of all salivary gland tumors and 4–6 % of minor salivary gland tumors. We report a case of CA in the palate that was initially suspected to be malignant owing to the appearance of the lesion surface following a laser incision performed at another hospital. A 58-year-old woman presented with swelling of the palatal mucosa in the right maxillary molar area. Computed tomography and magnetic resonance imaging revealed a soft tissue mass; however, because the patient had a history of asthma and non-contrast imaging was selected for these imaging tests, the imaging findings did not differentiate between benign and malignant tumors. A diagnosis of CA was made based on hematoxylin and eosin staining and immunohistochemistry of the biopsy sample. The lesion was surgically removed from the palatal mucosa under general anesthesia. At the 12-month postoperative follow-up, the patient exhibited good healing with no evidence of recurrence.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 183-186"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Influence of inflammatory and nutritional indices on post-parotidectomy salivary fistula or sialocele in benign tumors 炎症和营养指标对良性肿瘤腮腺切除术后涎瘘或涎腺囊肿的影响

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-07-05 DOI: 10.1016/j.ajoms.2025.06.015

Qiwei Zeng , Ming Sheng , Si Ouyang , Bin Liu

{"title":"Influence of inflammatory and nutritional indices on post-parotidectomy salivary fistula or sialocele in benign tumors","authors":"Qiwei Zeng , Ming Sheng , Si Ouyang , Bin Liu","doi":"10.1016/j.ajoms.2025.06.015","DOIUrl":"10.1016/j.ajoms.2025.06.015","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to determine whether inflammatory and nutritional indices are associated with the formation of salivary fistula or sialocele following parotid benign tumor resection.</div></div><div><h3>Methods</h3><div>Retrospective analysis of 373 parotid tumor resection patients evaluated preoperative inflammatory or nutritional indices for predicting postoperative salivary fistula or sialocele. Binary logistic regression identified independent risk factors to construct a nomogram.</div></div><div><h3>Results</h3><div>Salivary fistula or sialocele occurred in 115 patients, yielding an incidence rate of 30.8 %. Binary logistic regression analysis demonstrated that postoperative duration of drainage, HALP score (Hemoglobin-Albumin-Lymphocyte-Platelet score) ≥ 49.2, and PNI (Prognostic Nutritional Index) ≥ 52.68 served as protective factors against salivary fistula or sialocele formation. Conversely, smoking was identified as a risk factor for salivary fistula or sialocele development, with all P-values < 0.05. Conclusions: HALP score, PNI, smoking, and duration of drainage are independent predictors of the occurrence of salivary fistula or sialocele after parotid benign tumor resection. The nomogram incorporating the indicators mentioned above can serve as a reference for clinicians to assess the occurrence of salivary fistula or sialocele following parotid benign tumor resection.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 36-42"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145475734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of parallel holes in bone regenerative material for vertical bone augmentation 骨再生材料中平行孔对垂直骨增强的影响

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-08-07 DOI: 10.1016/j.ajoms.2025.07.016

Toshiki Yanagisawa , Keiko Matsui , Yushi Ezoe , Atsumu Kouketsu , Kei-ichiro Miura , Tomohiro Yamada , Shinji Kamakura

{"title":"Influence of parallel holes in bone regenerative material for vertical bone augmentation","authors":"Toshiki Yanagisawa , Keiko Matsui , Yushi Ezoe , Atsumu Kouketsu , Kei-ichiro Miura , Tomohiro Yamada , Shinji Kamakura","doi":"10.1016/j.ajoms.2025.07.016","DOIUrl":"10.1016/j.ajoms.2025.07.016","url":null,"abstract":"<div><h3>Objective</h3><div>Recently, liquid nitrogen-treated octacalcium phosphate and collagen composite (OCPcol) has demonstrated reproducible bone augmentation. Previous studies suggested that orderly arranged unidirectional macropores could enhance bone formation within the implant. This study aimed to investigate whether different types of unidirectional macropores in liquid nitrogen-treated OCPcol influence bone augmentation.</div></div><div><h3>Methods</h3><div>Liquid nitrogen-treated OCPcol disks were prepared with parallel holes in the axial direction and divided into four groups: Open (through holes), Top (blind holes from top), Bottom (blind holes from bottom), and Untreated (no holes). These disks were implanted in rodent calvarial subperiosteal pockets. Bone formation and implant structure were evaluated after 12 weeks using radiomorphometric and histological analyses.</div></div><div><h3>Results</h3><div>Radiomorphometric analysis revealed that the Open group exhibited a greater degree of deformation compared to the other groups, but all groups maintained their height and shape overall. Histomorphometric analysis showed that appositional bone formation was primarily enhanced from the surface of the existing bone towards the inside of the implants. Among the groups, the Open group demonstrated the lowest appositional bone formation.</div></div><div><h3>Conclusions</h3><div>The addition of unidirectional macropores to OCPcol had a limited effect on appositional bone formation compared with the impact of liquid nitrogen treatment. These findings suggest that while macropores may play a role in bone regeneration, their effect is secondary to the structural and biological advantages conferred by liquid nitrogen-treated OCPcol.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"38 1","pages":"Pages 52-58"},"PeriodicalIF":0.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145475736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenomatoid hyperplasia of the minor salivary glands: Dr. Hamilton B.G. Robinson’s forgotten first report 小唾液腺腺瘤样增生：Hamilton B.G. Robinson医生被遗忘的第一份报告

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2026-01-01 Epub Date: 2025-07-30 DOI: 10.1016/j.ajoms.2025.07.014

Fumio Ide , Michiko Nishimura , Shinnichi Sakamoto, Kentaro Kikuchi

引用次数: 0