Journal of Oral and Maxillofacial Surgery Medicine and Pathology最新文献_第3页

Odontogenic keratocyst exhibiting dysplastic changes: Report of a new case in a 14-year-old and literature review

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-08-03 DOI: 10.1016/j.ajoms.2024.08.004

Jasbir D. Upadhyaya , Benjamin J. Schlott

{"title":"Odontogenic keratocyst exhibiting dysplastic changes: Report of a new case in a 14-year-old and literature review","authors":"Jasbir D. Upadhyaya , Benjamin J. Schlott","doi":"10.1016/j.ajoms.2024.08.004","DOIUrl":"10.1016/j.ajoms.2024.08.004","url":null,"abstract":"<div><div>Odontogenic keratocyst (OKC) is known for its aggressive behavior and a high tendency for recurrence. Malignant transformation in OKC has been widely reported, but comprehensive studies investigating the clinicopathological features and management strategies of dysplastic OKCs are limited. Herein, we report a new case of an OKC exhibiting premalignant changes in a 14-year-old patient and review published cases of dysplastic OKCs. The lesion presented as an incidental radiolucency in the anterior mandible. Histopathological evaluation revealed an intense inflammatory infiltrate in the connective tissue and severe epithelial dysplasia with focal areas exhibiting carcinoma <em>in situ</em>. The dysplastic epithelial lining expressed diffuse reactivity to p53 and displayed a Ki-67 proliferation index of more than 20 %. The lesion was excised by enucleation and thorough curettage. Uneventful healing was noted at the 6-month follow-up appointment. A review of the literature revealed that the average age of diagnosis of dysplastic OKC was 32 years. It showed a preference for the mandible; the most common sites were the anterior and left sides. Most lesions were treated with enucleation; recurrence was reported in one patient. Epithelial dysplasia arising in OKCs is not a frequent finding. A vigilant evaluation of the excised lesions, mainly those displaying significant inflammation, with p53 immunohistochemical analysis may help avoid a misdiagnosis. As OKCs can recur decades after initial treatment, patients with dysplastic lesions should be more closely followed up.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 380-384"},"PeriodicalIF":0.4,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143151374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Lefort-1 advancement by internal and external distraction osteogenesis in non-syndromic cleft lip and palate: A systematic review and meta-analysis 非综合征唇腭裂患者通过内外牵引成骨法进行 Lefort-1 推进的比较：系统回顾和荟萃分析

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-08-03 DOI: 10.1016/j.ajoms.2024.08.002

Sameer Pandey , Ashi Chug , Srinivas Gosla Reddy , Saurabh S. Simre

{"title":"Comparison of Lefort-1 advancement by internal and external distraction osteogenesis in non-syndromic cleft lip and palate: A systematic review and meta-analysis","authors":"Sameer Pandey , Ashi Chug , Srinivas Gosla Reddy , Saurabh S. Simre","doi":"10.1016/j.ajoms.2024.08.002","DOIUrl":"10.1016/j.ajoms.2024.08.002","url":null,"abstract":"<div><h3>Purpose</h3><div>In 25 % of Cleft lip and palate (CLP) patients, midface hypoplasia (MH) is non-responsive to orthodontics. Post-surgical scarring in cleft patients causes large relapse with conventional osteotomies. Distraction osteogenesis (DO) has become the choice of treatment for midface hypoplasia in CLP patient. The systematic review aims to generate evidence to guide the selection of distraction devices for non-syndromic CLP associated maxillary hypoplasia.</div></div><div><h3>Materials and methods</h3><div>A PRISMA-guided systematic review was planned. Studies with LeFort 1 distraction osteogenesis in non-syndromic CLP patients were included. Four literature databases (PubMed, Embase, Cochrane and Ovid) were searched. Identified studies were shortlisted based on PICOS criteria for data extraction. SNA, SNB and ANB angle measurements were extracted pre-distraction and within 1 year and after 1-year post-distraction. Forest plots were generated to understand the maxillary advancement and relapse associated with external and internal distractor. Risk of bias was evaluated for non-randomized studies and a traffic light plot as well as summary plot was generated for inference.</div></div><div><h3>Results</h3><div>A total of 2395 articles were identified after a database search. 131 articles were included for full-text review and 31 articles were selected for data synthesis. A total of 361 patients underwent distraction osteogenesis, out of which 265 patients underwent external DO, and 96 underwent internal DO. Pooled data analysis revealed a larger increase in SNA angle for external distractors than internal distractors.</div></div><div><h3>Conclusion</h3><div>External DO provide a greater degree of midface advancement than internal DO. The degree of relapse is more with external distraction.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 23-30"},"PeriodicalIF":0.4,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory myofibroblastic tumor suspected of being a malignant tumor arising in the anterior mandible

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-08-03 DOI: 10.1016/j.ajoms.2024.08.003

Ryosuke Kubota , Masahiro Watanabe , Yusuke Nishiguchi , Haruka Arai , Takako Yamaguchi , Sho Mitsugi , Hirohito Kubo , Toshihiko Takenobu

{"title":"Inflammatory myofibroblastic tumor suspected of being a malignant tumor arising in the anterior mandible","authors":"Ryosuke Kubota , Masahiro Watanabe , Yusuke Nishiguchi , Haruka Arai , Takako Yamaguchi , Sho Mitsugi , Hirohito Kubo , Toshihiko Takenobu","doi":"10.1016/j.ajoms.2024.08.003","DOIUrl":"10.1016/j.ajoms.2024.08.003","url":null,"abstract":"<div><div>Inflammatory myofibroblastic tumors are a neoplastic lesions consisting mainly of myofibroblast proliferation, accompanied by marked infiltrations of inflammatory cells (e.g., lymphocytes and plasma cells); they rarely occur in the jawbone. We describe an inflammatory myofibroblastic tumor that occurred in the anterior mandible and was suspected to be malignant. The patient, a 47-year-old Japanese woman, went to a dentist because of pain in a mandibular anterior tooth. The tooth was extracted due to severe mobility, but after a failure of healing, the patient was referred to our hospital. Compressive bone resorption in the anterior mandible and swelling of both submandibular lymph nodes were observed. Antibiotics were administered, but due to enlargement, a malignant tumor was suspected. FDG-PET and a biopsy were performed. Based on the diagnosis of inflammatory myofibroblastic tumor, tumor resection was performed (general anesthesia). The patient is well at 3 years postsurgery without recurrence or metastasis.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 313-317"},"PeriodicalIF":0.4,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143150264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epstein–Barr virus-positive mucocutaneous ulcer arising in the oral region: A report of three cases and a review

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-08-03 DOI: 10.1016/j.ajoms.2024.07.011

Kenta Tanaka , Takazumi Yasui , Takeshi Karube , Hiroki Nagamine , Moemi Kimura , Rie Kodaka , Seiji Asoda , Hideki Orikasa , Katsuhiro Onizawa

{"title":"Epstein–Barr virus-positive mucocutaneous ulcer arising in the oral region: A report of three cases and a review","authors":"Kenta Tanaka , Takazumi Yasui , Takeshi Karube , Hiroki Nagamine , Moemi Kimura , Rie Kodaka , Seiji Asoda , Hideki Orikasa , Katsuhiro Onizawa","doi":"10.1016/j.ajoms.2024.07.011","DOIUrl":"10.1016/j.ajoms.2024.07.011","url":null,"abstract":"<div><div>Epstein–Barr virus (EBV)-positive mucocutaneous ulcers (EBVMCUs) are localized mucosal or cutaneous ulcers caused by the proliferation of EBV-infected B cells in patients with immunosuppression. To reach an appropriate diagnosis of EBVMCUs, which have a favorable prognosis distinct from EBV-positive diffuse large B-cell lymphoma (EBV-positive DLBCL) with a poor prognosis, clinicopathological features of cases must be understood. Herein, we describe our experience with three cases of EBVMCUs in the oral cavity and review the literature. In case 1, a 56-year-old woman received methotrexate (MTX) and prednisolone for the treatment of psoriatic arthritis．After teeth extraction, ulcers formed, and bone exposure with necrotic-like tissues was observed. In case 2, a 73-year-old woman received MTX for the treatment of rheumatoid arthritis (RA). After tooth extraction, an ulcer was formed with bone exposure. In case 3, a 60-year-old woman received MTX for the treatment of RA. A well-defined ulcer was found on the left ventral surface of the tongue. All patients showed lesion resolution after MTX withdrawal. Since most EBVMCUs show a favorable prognosis distinct from EBV-positive DLBCL with a poor prognosis, an appropriate diagnosis is necessary.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 340-347"},"PeriodicalIF":0.4,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143150327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examination of the duration of vitamin B12 administration for hypoesthesia caused by inferior alveolar nerve injury after horizontally impacted mandibular third molar: A retrospective study 研究下颌第三磨牙水平撞击后下牙槽神经损伤引起的低痛症服用维生素B12的持续时间：回顾性研究

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-08-02 DOI: 10.1016/j.ajoms.2024.07.010

Takumi Shimura, Ken-ichiro Sakata, Hiroyuki Hato, Haruhisa Watanabe, Takuya Asaka, Jun Sato, Yoshimasa Kitagawa

{"title":"Examination of the duration of vitamin B12 administration for hypoesthesia caused by inferior alveolar nerve injury after horizontally impacted mandibular third molar: A retrospective study","authors":"Takumi Shimura, Ken-ichiro Sakata, Hiroyuki Hato, Haruhisa Watanabe, Takuya Asaka, Jun Sato, Yoshimasa Kitagawa","doi":"10.1016/j.ajoms.2024.07.010","DOIUrl":"10.1016/j.ajoms.2024.07.010","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess the time to cure of hypoesthesia caused by inferior alveolar nerve (IAN) injury after horizontally impacted mandibular third molar (M3) extraction under continuous administration of mecobalamin, a vitamin B12 preparation, and factors that influence the time to cure.</div></div><div><h3>Methods</h3><div>This was a single-center retrospective study including 33 patients who experienced hypoesthesia after horizontally impacted M3 extraction and were treated with continuous oral administration of mecobalamin alone. The patients were divided into cured (n = 28) and uncured groups (n = 5). Demographic and clinical data were collected and analyzed.</div></div><div><h3>Results</h3><div>Of the 33 patients, 5 (15 %) reported uncured hypoesthesia. The median time to cure of hypoesthesia with mecobalamin administration was 33 (range, 6–202) days, and no cure beyond 7 months was reported. Age (≥30 years), Pell and Gregory classification (Position), and presence of Rood and Shehab signs (\"interruption of white line of canal\" and \"diversion of canal\") were significantly associated with prolonged time to cure.</div></div><div><h3>Conclusions</h3><div>It may be necessary to evaluate the efficacy of mecobalamin for IAN injury after horizontally impacted M3 extraction approximately 30 days after the initiation of administration and consider treatment modification or additional treatment within approximately 7 months.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 195-200"},"PeriodicalIF":0.4,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mucoepidermoid carcinoma arising in salivary hyperplasia of the hard palate in a pediatric patient 一名儿童患者硬腭唾液腺增生引发的黏液表皮样癌

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-25 DOI: 10.1016/j.ajoms.2024.07.006

Eri Yumoto , Ryo Kajihara , Yuki Sakai , Shin-ichi Yamada , Takeshi Koike , Hiroshi Kurita

{"title":"Mucoepidermoid carcinoma arising in salivary hyperplasia of the hard palate in a pediatric patient","authors":"Eri Yumoto , Ryo Kajihara , Yuki Sakai , Shin-ichi Yamada , Takeshi Koike , Hiroshi Kurita","doi":"10.1016/j.ajoms.2024.07.006","DOIUrl":"10.1016/j.ajoms.2024.07.006","url":null,"abstract":"<div><div>Primary malignant salivary gland tumors are rare among pediatric patients. There are few reports about mucoepidermoid carcinoma (MEC) in the minor salivary gland in pediatric patients. Herein, we report a case of MEC that arose in salivary hyperplasia on the hard palate in a 10-year-old girl. A 10-year-old girl presented with swelling on the left side of the hard palate. She was referred to our department in October 202X. The patient had experienced swelling of the left hard palate for 2 years, which had been slowly increasing in size. Upon examination, a single, dome-shaped, well-defined mass measuring 18 × 12 mm was observed. Mucosa was normal and there was no tenderness on the left hard palate. The mass showed low signal intensity on T2-weighted magnetic resonance imaging. A biopsy was performed. Although the result indicated salivary hyperplasia, due to suspicion of tumor, total resection was performed. We resected the mass along with the periosteum and removed one layer of the palatal bone under general anesthesia. Histopathologic examination of the surgical specimen revealed low-grade mucoepidermoid carcinoma. We performed careful follow-up. There was no evidence of recurrence as of 2 years post-surgery.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 308-312"},"PeriodicalIF":0.4,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141839739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healing of tooth extraction wound socket, do we have current understanding? 拔牙创口的愈合，我们目前了解多少？

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-20 DOI: 10.1016/j.ajoms.2024.07.009

Aqsa Kamal , Maryam Kamal , Alina Hasnat , Abeera Mohsin , A.R. Samsudin

{"title":"Healing of tooth extraction wound socket, do we have current understanding?","authors":"Aqsa Kamal , Maryam Kamal , Alina Hasnat , Abeera Mohsin , A.R. Samsudin","doi":"10.1016/j.ajoms.2024.07.009","DOIUrl":"10.1016/j.ajoms.2024.07.009","url":null,"abstract":"<div><h3>Objective</h3><div>This review paper aims to provide an up to date understanding on tooth socket healing signifying the impact of osteoimmunology, cellular and molecular events, role of nerves, growth factors, signaling pathways, oxygen, endocrine and obesity in healing and regeneration.</div></div><div><h3><strong>Methods</strong></h3><div>A thorough literature search was conducted using up to date software and electronic databases including Python 3.9.7 and latent Dirichlet allocation (LDA).</div></div><div><h3><strong>Results</strong></h3><div>70 relevant articles were included. Tooth socket healing is different from other types of bone healing.</div></div><div><h3><strong>Conclusion</strong></h3><div>Role of osteoimmunology, macrophages, mesenchymal stem cells, growth factors, hormones and nerves in tooth socket healing have been ignored for long. These factors can result in impaired wound healing or disruption the healing process. Understanding the mechanisms involved in tooth socket healing can contribute to the development of targeted strategies for promoting optimal healing outcomes.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 8-22"},"PeriodicalIF":0.4,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of ubiquinone to improve the healing of soft and hard jaw tissues – A systematic review 使用泛醌改善颌骨软组织和硬组织的愈合--系统综述

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-19 DOI: 10.1016/j.ajoms.2024.07.008

Alini Cardoso Soares , Camila Barcellos Calderipe , Rafael dos Santos Giorgis , Luisa Quevedo Grave , Antonio Cesar Manentti Fogaça , Marcos Antonio Torriani , Ana Carolina Uchoa Vasconcelos , Lauren Frenzel Schuch

{"title":"The use of ubiquinone to improve the healing of soft and hard jaw tissues – A systematic review","authors":"Alini Cardoso Soares , Camila Barcellos Calderipe , Rafael dos Santos Giorgis , Luisa Quevedo Grave , Antonio Cesar Manentti Fogaça , Marcos Antonio Torriani , Ana Carolina Uchoa Vasconcelos , Lauren Frenzel Schuch","doi":"10.1016/j.ajoms.2024.07.008","DOIUrl":"10.1016/j.ajoms.2024.07.008","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of the present study was to survey the scientific literature for conclusive evidence about the capacity of ubiquinone to improve the healing process of soft and hard jaw tissue.</div></div><div><h3>Methods</h3><div>A systematic review was conducted according to the PRISMA 2020 statement. An electronic search was undertaken in six databases and in the gray literature<strong>.</strong></div></div><div><h3>Results</h3><div>Eight studies were identified, four of them <em>in vitro,</em> three <em>in vivo,</em> and one clinical. All articles demonstrated that ubiquinone accelerates the repair of soft tissue, whereas one study found little effect on the remodeling of bone tissue. Despite the possibility that ubiquinone application may be beneficial, the limited knowledge about the action of this coenzyme on oral tissue repair requires further preclinical studies before the development of human clinical trials.</div></div><div><h3>Conclusion</h3><div>This systematic review provides valuable information about potential new medications that could help the healing of oral tissues, especially for oral and maxillofacial surgeons.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 1","pages":"Pages 157-166"},"PeriodicalIF":0.4,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) following stomatitis 一例口腔炎后的药物过敏综合征（DIHS）/嗜酸性粒细胞增多和全身症状的药物反应（DRESS）病例

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-17 DOI: 10.1016/j.ajoms.2024.07.007

Masafumi Nakamoto , Akiyuki Hirosue , Kazuhito Tanaka , Hikaru Nakashima , Junki Inoue , Nozomu Takahashi , Daiki Fukuma , Yuichiro Matsuoka , Takuya Tanaka , Yoshihiro Yoshitake , Hideki Nakayama

{"title":"A case of drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) following stomatitis","authors":"Masafumi Nakamoto , Akiyuki Hirosue , Kazuhito Tanaka , Hikaru Nakashima , Junki Inoue , Nozomu Takahashi , Daiki Fukuma , Yuichiro Matsuoka , Takuya Tanaka , Yoshihiro Yoshitake , Hideki Nakayama","doi":"10.1016/j.ajoms.2024.07.007","DOIUrl":"10.1016/j.ajoms.2024.07.007","url":null,"abstract":"<div><div>Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS) is a severe form of drug-related rash with distinct features. This condition is characterized by late onset from specific causative drugs, and symptoms worsen despite discontinuation of the causative agent, followed by organ dysfunction. Notably, DIHS/DRESS results from the reactivation of human herpesvirus 6 (HHV-6). Herein, we report a case of DIHS/DRESS in which rash, fever and liver dysfunction were observed during hospitalization for stomatitis, and HHV-6 reactivation was confirmed. A 67-year-old man who had been taking carbamazepine for the sequelae of cerebral hemorrhage was referred to our hospital because of pain in the oral mucosa. Initially, he was diagnosed with a herpes virus infection and treated with acyclovir. Afterward, despite improvement in stomatitis, papules appeared on the trunk of the body and worsened. The symptoms were accompanied by fever and liver dysfunction. Eventually, the patient developed decreased systolic blood pressure, tachypnea, and atrial fibrillation. After pulse steroid therapy was initiated, the patient’s clinical condition improved. Real-time polymerase chain reaction was performed suspecting with DIHS/DRESS, and HHV-6 DNA was detected. Based on this process, we diagnosed the patient with DIHS/DRESS induced by carbamazepine.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 333-339"},"PeriodicalIF":0.4,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraosseous xanthoma of the fronto-malar suture: Case report and literature review 骨内前臼齿缝黄瘤：病例报告和文献综述。

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Journal of Oral and Maxillofacial Surgery Medicine and Pathology Pub Date : 2024-07-14 DOI: 10.1016/j.ajoms.2024.07.001

Gilli Massimiliano , Sacchi Federica , Prosperini Annapaola , Giovacchini Francesco , Mitro Valeria , Committeri Umberto , Tullio Antonio

{"title":"Intraosseous xanthoma of the fronto-malar suture: Case report and literature review","authors":"Gilli Massimiliano , Sacchi Federica , Prosperini Annapaola , Giovacchini Francesco , Mitro Valeria , Committeri Umberto , Tullio Antonio","doi":"10.1016/j.ajoms.2024.07.001","DOIUrl":"10.1016/j.ajoms.2024.07.001","url":null,"abstract":"<div><div>Intraosseous xanthomas<span><span><sup>1</sup></span></span> (IOX) are rare benign lesions characterized by the deposition of lipid-laden histiocytes within bone tissue. We present a case of IOX involving the fronto-malar suture in a 71-year-old male patient, which is an unusual location for this lesion. The patient presented with a painless swelling over his left fronto-malar region, which had been progressively enlarging over several months. Clinical examination and imaging studies revealed a well-defined radiolucent lesion involving the fronto-malar suture. Surgical excision was performed, and histopathological examination confirmed the diagnosis of IOX. The patient had an uncomplicated postoperative course with no evidence of recurrence at the follow-up. The literature review highlighted 47 cases of IOX. The distribution of these lesions in the facial bones is prevalent in the mandible (77 %). Other localizations are rare. This case highlights the importance of considering intraosseous xanthoma in the differential diagnosis of radiolucent lesions involving craniofacial bones.</div></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"37 2","pages":"Pages 371-375"},"PeriodicalIF":0.4,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0