Journal of Audiology and Otology最新文献

{"title":"Combination Therapy of Choline Alfoscerate With Ginkgo biloba Monotherapy in Age-Related Hearing Loss: Effects and Outcomes.","authors":"Dae Hyun Kim, Young Joon Seo","doi":"10.7874/jao.2023.00192","DOIUrl":"10.7874/jao.2023.00192","url":null,"abstract":"<p><strong>Background and objectives: </strong>Ginkgo biloba and choline alfoscerate are used as adjuvant treatment for presbycusis, but studies on how the monotherapy differs from the combination therapy are lacking. Therefore, this study aimed to compare the audiologic outcomes between Ginkgo biloba monotherapy and Ginkgo biloba and choline alfoscerate combination therapy. Subjects and.</p><p><strong>Methods: </strong>The study groups are divided into three: negative control, monotherapy, and combination therapy groups. All groups' pure tone audiometry was measured by dividing the study period into Initial, 3-6, 6-9, 9-12, 12-15 months, and checked whether differences between groups were present.</p><p><strong>Results: </strong>The combination therapy showed less gradient gap than the monotherapy, indicating less hearing loss rate than the monotherapy. Based on the Kaplan-Meier curve, the combination therapy showed better results in terms of survival time of hearing.</p><p><strong>Conclusions: </strong>As a pharmacological treatment for presbycusis, combination therapy shows better results than monotherapy.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"59-66"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological Treatment of Acute Unilateral Vestibulopathy: A Review.","authors":"Francisco Alves de Sousa, Clara Serdoura Alves, Ana Nóbrega Pinto, Luís Meireles, Ângela Reis Rego","doi":"10.7874/jao.2023.00066","DOIUrl":"10.7874/jao.2023.00066","url":null,"abstract":"<p><p>There have been few investigations on the epidemiology, etiology, and medical management of acute unilateral vestibulopathy (AUV). Short-term pharmaceutical resolutions include vestibular symptomatic suppressants, anti-emetics, and some cause-based therapies. Anticholinergics, phenothiazines, antihistamines, antidopaminergics, benzodiazepines, and calcium channel antagonists are examples of vestibular suppressants. Some of these medications may show their effects through multiple mechanisms. In contrast, N-acetyl-L-leucine, Ginkgo biloba, and betahistine improve central vestibular compensation. Currently, AUV pathophysiology is poorly understood. Diverse hypotheses have previously been identified which have brought about some causal treatments presently used. According to some publications, acute administration of anti-inflammatory medications may have a deleterious impact on both post-lesional functional recovery and endogenous adaptive plasticity processes. Thus, some authors do not recommend the use of corticosteroids in AUV. Antivirals are even more contentious in the context of AUV treatment. Although vascular theories have been presented, no verified investigations employing anti-clotting or vasodilator medications have been conducted. There are no standardized treatment protocols for AUV to date, and the pharmacological treatment of AUV is still questionable. This review addresses the most current developments and controversies in AUV medical treatment.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"18-28"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Correlation Between the Visually Induced Motion Sickness Susceptibility Questionnaire and the Turkish Motion Sickness Susceptibility Questionnaire.","authors":"Emel Ugur","doi":"10.7874/jao.2023.00122","DOIUrl":"10.7874/jao.2023.00122","url":null,"abstract":"<p><strong>Background and objectives: </strong>Visually induced motion sickness (VIMS) is a phenomenon similar to motion sickness frequently observed in users of visual technologies. The Visually Induced Motion Sickness Susceptibility Questionnaire (VIMSSQ), developed by Golding et al. (2006), is considered the most effective scale for assessing VIMS susceptibility levels. The main purpose of this study was to standardize the selection of participants for research conducted with virtual reality, especially motion sickness (MS) research. To achieve this, first, the Turkish version of the VIMSSQ was created to establish its validity and reliability, and subsequently, its correlation with the Turkish Motion Sickness Susceptibility Questionnaire Short form (HDDA), the expanded version of the Motion Sickness Susceptibility Questionnaire Short form (MSSQ), was examined. Subjects and.</p><p><strong>Methods: </strong>Linguistic equivalence assessment was obtained from ten experts by passing the VIMSSQ through the translation process. The VIMSSQ and the Turkish MSSQ forms were then administered to 49 subjects. This study statistically analyzed the validity and reliability of the VIMSSQ and its relationship with the MSSQ.</p><p><strong>Results: </strong>Results showed that the Turkish version of the original questionnaire is highly reliable (Cronbach alpha=0.843). There is a moderate statistically significant positive correlation between the total MSSQ scores and the subfactors of the VIMSSQ.</p><p><strong>Conclusions: </strong>In this study, VIMSSQ was successfully adapted to Turkish, normative data demonstrated its validity, and all sub-factors were highly reliable. The Turkish version of the VIMSSQ can serve as a valuable tool for estimating individual susceptibility to VIMS.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"36-43"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Distributions of Hearing Threshold Levels by Ages: A Comparison of the ISO 7029 and Newly Available Country-Specific Data.","authors":"In-Ki Jin, Donghyeok Lee, Youngchan Jeong, Young Jun Seo, Tae Hoon Kong, Michelle J Suh, Wan-Ho Cho, Hyo-Jeong Lee, Seong Jun Choi, Dongchul Cha, Kyung-Ho Park, Soo Hee Oh","doi":"10.7874/jao.2023.00626","DOIUrl":"10.7874/jao.2023.00626","url":null,"abstract":"<p><p>Hearing thresholds provide essential information and references about the human auditory system. This study aimed to identify changing trends in distributions of hearing threshold levels across ages by comparing the International Organization for Standardization (ISO) 7029 and newly available data after publishing ISO 7029. To compare ISO 7029 and newly available hearing threshold data after publishing ISO 7029, four country-specific datasets that presented average hearing threshold levels under conditions similar to ISO 7029 were utilized. For frequencies between 125 Hz and 8,000 Hz, the deviations of hearing threshold values by ages from the hearing threshold of the youngest age group for each data point were utilized. For frequencies from 9,000 Hz to 12,500 Hz, the median threshold information was utilized. Hearing threshold data reported after publishing ISO 7029 from the four countries were mostly similar to the ISO 7029 data but tended to deviate in some age groups and sexes. As national hearing threshold trends change, the following ISO 7029 revision suggests the need to integrate hearing threshold data from different countries.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"28 1","pages":"1-9"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139522083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary Review of Idiopathic Sudden Sensorineural Hearing Loss: Management and Prognosis.","authors":"Hyeon A Lee, Jae Ho Chung","doi":"10.7874/jao.2024.00024","DOIUrl":"10.7874/jao.2024.00024","url":null,"abstract":"<p><p>Sudden sensorineural hearing loss (SSNHL) is a rapid decline in auditory function that needs urgent medical management. Although etiologic factors, including viral infections, autoimmune diseases, and vascular issues, contribute to the understanding of SSNHL, the condition remains unclear in most cases. Systemic steroids are often used as the first-line treatment because they reduce inner ear inflammation; however, there remains numerous discussions about the effectiveness of alternative treatments. To predict hearing recovery is crucial in patients' counseling with factors, including delayed treatment, vertigo, and other health conditions, which indicate poor prognosis. Herein, we review contemporary research on the treatment approaches and outcome predictions of SSNHL to establish important guidelines for physicians in evaluating and treating patients with SSNHL.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"28 1","pages":"10-17"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139522129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First Cases of Sudden Sensorineural Hearing Loss Post Coronavirus Disease in Children.","authors":"Konstantina Chrysouli, Ioannis Pavlos Savva, Sotirios Karamagkiolas","doi":"10.7874/jao.2023.00227","DOIUrl":"10.7874/jao.2023.00227","url":null,"abstract":"<p><p>To investigate the incidence, characteristics, diagnosis, treatment, and prognosis of coronavirus disease (COVID-19)-related sudden sensorineural hearing loss (SSNHL) in children, three cases of SSNHL after COVID-19 infection in children were analyzed. ENT clinical examination of all cases was normal. Only the third child had a first degree left-beating optokinetic nystagmus, compatible with right peripheral vestibulopathy. The audiogram indicated unilateral severe SSNHL in all frequencies. Computed tomography and magnetic resonance imaging of the brain and temporal bones also showed absence of pathology of the related structures. Oral methylprednisolone was administered to the first two cases, whereas intravenous methylprednisolone in a tapering form was administered to the third case. Additionally, the children underwent intratympanic dexamethasone injections and hyperbaric oxygen therapy with hearing improvement in lower and middle frequencies. The prognosis of COVID-19-related SSNHL in children is closely related to the onset of treatment. The combination of glucocorticoids, intratympanic dexamethasone injections, and hyperbaric oxygen therapy could be effective for COVID- 19-related SSNHL in children. Further large-scale, multicenter studies should be conducted to investigate the pathophysiology, diagnosis, treatment, and prognosis of COVID- 19-related SSNHL.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"67-71"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Sudden Bilateral Neurosensory Hearing Loss as a Presentation of Lyme Neuroborreliosis: A Case Study.","authors":"Sara Rochd, Othmane Benhoummad, Salma Salhi, Youssef Lakhdar, Youssef Rochdi, Abdelaziz Raji, Hamza Oualhadj, Youssef El Kamouni, Said Zouhair","doi":"10.7874/jao.2023.00129","DOIUrl":"10.7874/jao.2023.00129","url":null,"abstract":"<p><p>Lyme neuroborreliosis (LNB) is a rare but potentially serious manifestation of Lyme disease, caused by the spirochete Borrelia burgdorferi. Although LNB can affect various neurological systems, neurosensory hearing loss as the sole presentation is uncommon. We report a case of a 23-year-old woman who presented with a 2-month history of temporal headache, tinnitus, and instability, which was followed by sudden bilateral hearing loss without any other associated symptoms. Pure-tone audiometry revealed profound bilateral hearing loss. Serological testing for various pathogens was negative, except for B. burgdorferi IgM, which was confirmed using Western blot analysis. The patient received doxycycline treatment; unfortunately, no recovery of hearing was observed. This case report highlights the importance of considering LNB as a potential cause of neurosensory hearing loss, particularly in areas where Lyme disease is endemic, as well as the need for timely diagnosis and treatment to prevent potential complications.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"72-75"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis Exploring the Effects of Music Training in Cochlear Implant Users by Age.","authors":"Nor Farawaheeda Ab Shukor,&nbsp;Young Joon Seo,&nbsp;Woojae Han","doi":"10.7874/jao.2023.00087","DOIUrl":"10.7874/jao.2023.00087","url":null,"abstract":"<p><strong>Background and objectives: </strong>The present study aimed to explore meaningful change in the musical performance of cochlear implant (CI) users according to age after receiving music training compared to the other CI users who did not receive any music training and normal hearing (NH) listeners. Materials and.</p><p><strong>Methods: </strong>Article search was conducted from five journal databases. In accordance with PICOS criteria, 29 articles and 15 articles were included for the CI and NH groups, respectively. A total of 44 articles consisting of 407 CI users and 486 NH participants were then analyzed. Using the data gathered from pre- and post-training, meta-analysis was applied by the random-effects model, and then piecewise meta-regression was employed.</p><p><strong>Results: </strong>CI users with music training showed better performance than those without the training across all ages. The curve change in musical performance when training showed that the CI users was similar to the general pattern of NH performance, indicating that the CI users gained benefits from music training and developed perceptual ability, even though it was not as high as the level of NH counterparts.</p><p><strong>Conclusions: </strong>This finding supports the benefits of active engagement with music for both CI users and NH listeners, while noting the important role of music as one of the primary aural rehabilitation approaches.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"193-204"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2c/e0/jao-2023-00087.PMC10603281.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Cases of Multiple Ossicular Chain Disruption After Penetrating Injury and Tympanic Membrane Healing.","authors":"Sola Han,&nbsp;Cha Dong Yeo,&nbsp;Eun Jung Lee","doi":"10.7874/jao.2022.00556","DOIUrl":"10.7874/jao.2022.00556","url":null,"abstract":"<p><p>Ossicular chain disruption is a typical consequence of temporal bone trauma. However, it can also occur as a result of direct trauma to the ossicular chain due to penetrating injuries. Hearing loss, dizziness, and facial nerve damage could also occur after penetrating middle ear injuries. Multiple ossicular chain disruption is a rare traumatic ossicular complication caused by direct penetrating lesions in the external auditory canal. We present two cases of multiple ossicular disruptions (dislocation of the incudostapedial and malleoincudal joints) after ear-pick injuries, both of which resulted in conductive hearing loss. The condition improved after delayed surgical intervention (ossiculoplasty).</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":" ","pages":"246-250"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/ce/jao-2022-00556.PMC10603280.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implantation in the Elderly: Speech Performance, Associated Factor, Complication, and Surgical Safety.","authors":"Minji Oh,&nbsp;Eun Jung Oh,&nbsp;Boseung Jung,&nbsp;Myung Hoon Yoo,&nbsp;Shin Young Yoo,&nbsp;Da Jung Jung,&nbsp;Kyu-Yup Lee","doi":"10.7874/jao.2023.00136","DOIUrl":"10.7874/jao.2023.00136","url":null,"abstract":"<p><strong>Background and objectives: </strong>The guidelines for cochlear implantation (CIs) are expanding, and the number of CI procedures performed on the elderly is increasing. The purpose of this study was to analyze the results and safety of cochlear implantation in the elderly, as well as to evaluate the predictive factors on CI outcomes.</p><p><strong>Subjects and methods: </strong>The study included 56 patients aged ≥40 years, who received CIs between 2009 and 2020. They were divided into two groups: 27 younger adults (40-64 years) and 29 elderly (>64 years). The study compared their pre- and postoperative speech perception and category of auditory performance (CAP) scores, surgical complications, and hospitalization periods. It also evaluated associated factors in the elderly group by examining categorical and continuous variables and postoperative CAP score.</p><p><strong>Results: </strong>There was a significant improvement in speech recognition tests (both word and sentence) and CAP scores in both groups compared to the pre-implantation scores (p<0.001). Postoperative results were slightly lower in the elderly group than in younger adults for sentence recognition and CAP scores, except for word recognition. No significant associated factors were found on postoperative CAP scores, except for etiology. Postoperative CAP significantly improved in the sudden hearing loss group compared to the groups with other etiologies (p=0.045). The elderly group had more comorbidities than that in the younger adult group (p=0.026), but there were no significant differences in postoperative complications and hospitalization periods.</p><p><strong>Conclusions: </strong>While speech recognition and CAP scores were relatively lower in the elderly group compared to the younger adults, the elderly group showed significant improvements in audiological results after CI. Moreover, CI was safe and well tolerated in elderly patients.</p>","PeriodicalId":44886,"journal":{"name":"Journal of Audiology and Otology","volume":"27 4","pages":"205-211"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/c7/jao-2023-00136.PMC10603278.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}