Advances in Gerontology最新文献_第4页

The Renewed ‘Advances in Gerontology’ 2025: Results, Prospects, Changing Strategy 更新的“老年学进展”2025：结果，前景，变化的战略

IF 0.5

Advances in Gerontology Pub Date : 2025-08-25 DOI: 10.1134/S2079057025600429

A. N. Khokhlov

{"title":"The Renewed ‘Advances in Gerontology’ 2025: Results, Prospects, Changing Strategy","authors":"A. N. Khokhlov","doi":"10.1134/S2079057025600429","DOIUrl":"10.1134/S2079057025600429","url":null,"abstract":"Editor-in-Chief of ‘Advances in Gerontology,’ who took over the journal in 2023, analyzes the path the journal has taken over the past 1.5 years and reflects on the prospects for its further development. It is emphasized that the initial idea, according to which the edition was to focus exclusively on articles on fundamental (molecular, biochemical, cellular, etc.) mechanisms of aging and longevity, apparently turned out to be untenable. It had to admit the importance of publishing articles in the journal that touch upon other areas of gerontological research, in particular—psychology, sociology, demography, and medicine. It is now becoming quite clear that such work is no less important for understanding the essence of aging, as well as for prolonging healthy life, than so-called fundamental research. And perhaps even more important. In this regard, the corresponding specialists were introduced to the Editorial Board. Gerontological works devoted to the problem of falls in the elderly are specially considered, their undoubted importance for the whole society is emphasized. It is noted that over the past time, the journal’s scientometric indicators have increased significantly, and the geography of the authors of the published articles has greatly expanded—including due to the increase in the number of research areas covered. It is emphasized that recently published works on the psychology and sociology of aging have become among the most viewed and downloaded articles of the edition. The author of this Editorial hopes that the growing interest in the journal will attract new researchers involved in both theoretical and experimental, as well as clinical or social gerontology.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 2","pages":"43 - 45"},"PeriodicalIF":0.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 0.5

Advances in Gerontology Pub Date : 2025-08-25 DOI: 10.1134/S2079057025600326

E. P. Antonova, V. A. Ilyukha, A. E. Yakimova, I. V. Baishnikova, T. N. Ilyina

{"title":"Age-Related Changes in the Tissue Antioxidant Defense of the Northern Birch Mouse (Sicista betulina, Rodentia) at the Northern Periphery of Its Range","authors":"E. P. Antonova, V. A. Ilyukha, A. E. Yakimova, I. V. Baishnikova, T. N. Ilyina","doi":"10.1134/S2079057025600326","DOIUrl":"10.1134/S2079057025600326","url":null,"abstract":"The study is aimed at determining tissue antioxidant levels in juvenile and adult northern birch mice (Sicista betulina Pallas, 1779) at the northern periphery of its range (Republic of Karelia). Our results indicate a mixed pattern of age-related changes in the antioxidant defense system: aging is accompanied by a decrease in catalase activity in the kidneys as well as an increase in heart catalase activity and kidney, cardiac, and skeletal muscle superoxide dismutase activity. The levels of low-molecular antioxidants, i.e., reduced glutathione (GSH) (kidneys and heart) and α-tocopherol (heart and skeletal muscle), are lower in juvenile northern birch mice compared to adults animals, which is probably associated not only with the active growth and high mobility of juvenile mice during the dispersal period, but also with the stress of physiological systems due to living in northern conditions and preparing for hibernation. Higher levels of GSH and α-tocopherol are found in the hearts of adult northern birch mice compared to other small mammal species of the order Rodentia living in the Republic of Karelia, which indicates the important role of low-molecular weight antioxidants in protecting tissues against oxidative damage in this species.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 2","pages":"56 - 63"},"PeriodicalIF":0.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study 老年人体重指数与抑郁症状之间的相互作用：来自大规模人群队列研究的证据

IF 0.5

Advances in Gerontology Pub Date : 2025-06-03 DOI: 10.1134/S2079057024600757

E. Mohamadpour, A. Bijani, F. Kheirkhah, S. R. Hosseini, S. Moudi

{"title":"Interaction between Body Mass Index and Depressive Symptoms in Older Adults: Evidence from a Large-Scale Population-Based Cohort Study","authors":"E. Mohamadpour, A. Bijani, F. Kheirkhah, S. R. Hosseini, S. Moudi","doi":"10.1134/S2079057024600757","DOIUrl":"10.1134/S2079057024600757","url":null,"abstract":"There are mixed results on the correlation between body mass index and depressive symptoms among older adults. This observational research was carried-out as part of a prospective cohort study on older adults (aged 60 years and over) living in an urban region, north of Iran. Age, gender, marital status, the number of comorbid disorders, self-satisfaction with the household’s monthly income, and physical activity were assessed. The presence of depressive symptoms was examined and recorded by trained personnel using Geriatric Depression Scale (GDS). A total of 1000 older adults, including 544 (54.4%) men with a mean age of 69.82 ± 7.35 years were included. Findings showed that 747 (74.7%) of the participants had overweight or obesity; and 635 people (63.5%) had no depressive symptoms. A significant positive correlation was observed between GDS score and body mass index (BMI); although, the correlation was not strong (r = 0.077; p = 0.01). The correlation between GDS score and BMI was not statistically significant with two genders (r = –0.041, p = 0.38 for women, and r = 0.038, p = 0.37 for men). The multivariable linear regression model revealed the significant effect of gender (B = 0.56; p = 0.02) and the number of comorbidities (B = 0.49: p < 0.001) on GDS score. This large-scale population-based study demonstrated the positive correlation of BMI and depressive symptoms in old age. The effect of gender and comorbidities seems to be more significant on depression than that of BMI.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 1","pages":"18 - 25"},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145141817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats 升高骨骼肌GLUT4丰度不会导致限制卡路里诱导的雌性as160基因敲除大鼠骨骼肌胰岛素刺激葡萄糖摄取的升高

IF 0.5

Advances in Gerontology Pub Date : 2025-06-03 DOI: 10.1134/S2079057025600016

H. Wang, S. E. Kwak, A. F. Renaud, J. Hao, L. Kong, B. A. Fortman, X. Pan, D. Duan, G. D. Cartee

{"title":"Elevating Skeletal Muscle GLUT4 Abundance Does Not Result in a Calorie Restriction-Induced Elevation in Insulin-Stimulated Glucose Uptake by Skeletal Muscle from Female AS160-Knockout Rats","authors":"H. Wang, S. E. Kwak, A. F. Renaud, J. Hao, L. Kong, B. A. Fortman, X. Pan, D. Duan, G. D. Cartee","doi":"10.1134/S2079057025600016","DOIUrl":"10.1134/S2079057025600016","url":null,"abstract":"Calorie restriction (CR: ∼20–40% below AL: ad libitum intake) can increase insulin sensitivity in various species. We reported that CR did not induce an increase in insulin-stimulated glucose uptake (ISGU) by skeletal muscle from female Akt substrate of 160 kDa knockout (AS160-KO) rats. It seemed possible that the marked decline in muscle GLUT4 abundance, a characteristic of AS160-KO animals, played a role in our observation. We used an adeno-associated virus (AAV) approach to increase muscle GLUT4 abundance in female AS160-KO rats. We injected an AAV-GLUT4 vector into one epitrochlearis muscle. The contralateral epitrochlearis underwent sham injection and served as the control. Rats were randomly assigned to AL or CR (consuming 65% of AL intake) groups for 8-weeks. ISGU was determined in isolated muscles incubated ± insulin. Akt phosphorylation on regulatory sites (Threonine-308, pAktThr308 and Serine-473, pAktSer473) was determined to evaluate a key insulin signaling protein. The abundance of proteins that regulate ISGU (GLUT4 glucose transporter and hexokinase II) was determined by immunoblotting. We found: (1) AAV-delivery of GLUT4 to muscles successfully increased GLUT4 expression compared to sham-treated contralateral muscles in both diet groups; (2) this elevation in muscle GLUT4 did not result in a CR-induced increase in ISGU; (3) no significant diet-related differences were detected for pAktThr308, pAktSer473 or abundance of GLUT4 and hexokinase II in the muscles with either sham treatment or AAV-GLUT4. These observations revealed that the absence of a CR-induced increase in muscle ISGU of female AS160-KO rats was not attributable to low muscle GLUT4 abundance.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 1","pages":"1 - 9"},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145141999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geriatric Bariatrics and the Prevalence of Hypovitaminosis D in a Non-Large Urban Population: A Retrospective Study 非大城市人群的老年肥胖和维生素D缺乏症患病率：一项回顾性研究

IF 0.5

Advances in Gerontology Pub Date : 2025-06-03 DOI: 10.1134/S2079057025600107

T. R. Koch, D. C. Cronin, A. Iranmanesh

{"title":"Geriatric Bariatrics and the Prevalence of Hypovitaminosis D in a Non-Large Urban Population: A Retrospective Study","authors":"T. R. Koch, D. C. Cronin, A. Iranmanesh","doi":"10.1134/S2079057025600107","DOIUrl":"10.1134/S2079057025600107","url":null,"abstract":"We previously described a high prevalence of hypovitaminosis D in an elderly, large urban obese population. Blood levels of vitamin D in other elderly, obese populations are not well defined. The hypothesis of this study is that elderly individuals develop lower vitamin D levels in a non-large urban, obese population. The aim of this study is to compare the prevalence of hypovitaminosis D in an obese population ≤64 years-old to an obese population ≥65 years-old. Obese individuals (n = 400) were seen in gastrointestinal clinic where determination of vitamin D was suggested. Study exclusions included an absent blood level of 25-hydroxy vitamin D or use of vitamin D supplementation at the time of their clinic visit. There are 170 eligible individuals: 97 are ≤64 years-old (mean 49.9 years) while 73 are ≥65 years old (mean 72.8 years). Mean body mass index (SD) of individuals ≤ age 64 years is 35.3 (3.7) kg/m2 and mean body mass index (SD) of individuals ≥ age 65 years is 34.7 (3.6) kg/m2 (p > 0.05). The overall prevalence of hypovitaminosis D is 64.1%. Chi-square analysis rejected the hypothesis that hypovitaminosis D is dependent upon age (p = 0.12). While there is a high prevalence of hypovitaminosis D in this study population, this study did not identify elderly patients developing a higher prevalence of hypovitaminosis D in this non-large urban obese population, perhaps due to dietary and/or environmental factors.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 1","pages":"37 - 41"},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145141997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Active Aging and the Use of Information and Communication Technologies among Older Adults in Rural Areas of Madrid, Spain: A Qualitative Exploratory Study 西班牙马德里农村地区老年人的积极老龄化和信息通信技术的使用：一项定性探索性研究

IF 0.5

Advances in Gerontology Pub Date : 2025-06-03 DOI: 10.1134/S2079057025600077

P. De Gea Grela, L. P. Gallardo-Peralta, S. García-Aguña, D. Fernández-Roses, R. Yusta-Tirado, E. Sánchez-Moreno

{"title":"Active Aging and the Use of Information and Communication Technologies among Older Adults in Rural Areas of Madrid, Spain: A Qualitative Exploratory Study","authors":"P. De Gea Grela, L. P. Gallardo-Peralta, S. García-Aguña, D. Fernández-Roses, R. Yusta-Tirado, E. Sánchez-Moreno","doi":"10.1134/S2079057025600077","DOIUrl":"10.1134/S2079057025600077","url":null,"abstract":"This study investigates how Information and Communication Technologies (ICTs) influence active ageing among older adults living in rural areas of Madrid, Spain. By addressing a gap in the literature regarding the intersection of digital inclusion and active ageing in rural contexts, this research contributes novel insights into the lived experiences of older individuals. A qualitative approach was adopted, involving semi-structured interviews with fifteen individuals aged 80 and over residing in rural areas. Data were analysed through inductive thematic analysis, emphasizing the relationship between ICT use and the pillars of active ageing (health, participation, lifelong learning and security). The findings reveal a dual impact of ICTs on active ageing. Participants identified ICTs as facilitators of social participation and emotional well-being, particularly through video calls with family members, which helped maintain social connections and reduce loneliness. ICTs also supported health-related behaviours, such as accessing online exercise programs, contributing to physical activity and cognitive engagement. However, concerns about privacy violations and external control challenged the sense of security, while fears of overuse and dependency on digital devices were seen as potential risks to autonomy. These challenges were exacerbated by limited digital literacy and accessibility in rural areas. This study highlights the potential of ICTs to align with the goals of active ageing by fostering health, participation, and security. However, the findings underscore the critical need for tailored interventions to address digital literacy and infrastructure deficits in rural contexts. Promoting equitable access and addressing privacy concerns are essential to harness the benefits of ICTs while mitigating their risks.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 1","pages":"26 - 36"},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145141816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults 土耳其式老年人生存意愿量表的心理测量特性评价

IF 0.5

Advances in Gerontology Pub Date : 2025-06-03 DOI: 10.1134/S2079057024600666

B. Kütük

{"title":"Evaluation of the Psychometric Properties of the Turkish Form of the Will-to-Live Scale in Older Adults","authors":"B. Kütük","doi":"10.1134/S2079057024600666","DOIUrl":"10.1134/S2079057024600666","url":null,"abstract":"The Will-to-Live (WTL) scale measures desire for life and life commitment across populations. However, psychometric evidence for a Turkish older adult WTL screening model is lacking. In this study, the WTL was first translated into Turkish using established procedures, followed by the collection of psychometric information on the Turkish form (WTL-T). Included in the study were community-dwelling older adults (aged 65–85 years) who could be considered representative of the older adult Turkish population, who were asked to complete the WTL scale, the Satisfaction with Life Scale, the Philadelphia Geriatric Center Morale Scale, the Geriatric Depression Scale, the Brief Resilient Coping Scale, as well as a single-item WTL and self-rated health. The exploratory and confirmatory factor analyses demonstrated an acceptable model fit of the WTL-T, yielding a single-factor model that explained 66.45% of the variance. Furthermore, the WTL-T was found to have high internal consistency (Cronbach α = 0.865) and convergent validity was demonstrated by the strong positive correlations identified through the single-item WTL question (r = 0.810, p < 0.001). The moderate to high correlations of the scale with theoretically related measures supported its concurrent validity (r = –0.299 to 0.742, all p’s < 0.01). The evidence presented in the present study identifies the WTL-T as a concise, appropriate and psychometrically sound instrument for the assessment of WTL in older adults living in Turkey.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"15 1","pages":"10 - 17"},"PeriodicalIF":0.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longevity Nation—Enhancing Research, Development and Education for Healthy Longevity 长寿之国--加强健康长寿的研究、开发和教育

IF 0.6

Advances in Gerontology Pub Date : 2025-03-19 DOI: 10.1134/S2079057025600089

I. Stambler, S. Lederman, S. J. Olshansky, H. Y. Cohen, B. Schumacher, S. Greenfield, V. Krizhanovsky, M. Grunewald, N. Barzilai, E. S. Gonos, Y. Yanay, N. Yivgi-Ohana, G. Atzmon, D. Z. Bar, U. Alon, S. Shen-Orr, E. Bischof, T. Strauss, N. Vita-More, V. Calabrese, A. B. Kozhokaru, M. Kyriazis, D. Kaminskiy, F. Miller, A. Trukhanov, V. Fraifeld, J. L. Cordeiro, R. Faragher

{"title":"Longevity Nation—Enhancing Research, Development and Education for Healthy Longevity","authors":"I. Stambler, S. Lederman, S. J. Olshansky, H. Y. Cohen, B. Schumacher, S. Greenfield, V. Krizhanovsky, M. Grunewald, N. Barzilai, E. S. Gonos, Y. Yanay, N. Yivgi-Ohana, G. Atzmon, D. Z. Bar, U. Alon, S. Shen-Orr, E. Bischof, T. Strauss, N. Vita-More, V. Calabrese, A. B. Kozhokaru, M. Kyriazis, D. Kaminskiy, F. Miller, A. Trukhanov, V. Fraifeld, J. L. Cordeiro, R. Faragher","doi":"10.1134/S2079057025600089","DOIUrl":"10.1134/S2079057025600089","url":null,"abstract":"On October 28–31, 2024, there took place the international conference, “Longevity Nation 2024— Enhancing Research, Development and Education for Healthy Longevity” in Bar-Ilan University, Ramat Gan, Israel (http://www.longevitynation.org/). This conference explored the challenges that rise from population aging, from interdisciplinary perspectives that reflect new science and technology, and many social, cultural, political, economic and philosophical concerns that aging raises. By bringing together leading Israeli and international voices in the longevity space—researchers, developers, investors, educators, decision makers and public figures—the Longevity Nation conference aimed to contribute to increasing the synergy of science, technology and aging society, and help advance ethical scientific and technological solutions for healthy longevity for the benefit of the entire society. As the conference emphasized, in this period of conflict in Israel and the Middle East, it is especially important to build up international collaboration as a basis for future positive development.","PeriodicalId":44756,"journal":{"name":"Advances in Gerontology","volume":"14 4","pages":"151 - 160"},"PeriodicalIF":0.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aging, Cancer, Metformin, Light Regime, Advances in Gerontology, Books, Verses, Music, Fine Art, etc. etc. Remembering Prof. Vladimir N. Anisimov 衰老、癌症、二甲双胍、光照制度、老年学进展、书籍、诗歌、音乐、美术等。纪念弗拉基米尔·n·阿尼西莫夫教授

IF 0.6

Advances in Gerontology Pub Date : 2025-03-19 DOI: 10.1134/S2079057025600119

A. N. Khokhlov, N. G. Kolosova, G. V. Morgunova

引用次数: 0

Antioxidants: Good, Bad, or Ineffective in Terms of Aging and Lifespan? It Depends 抗氧化剂：对衰老和寿命有益、有害还是无效？这取决于

IF 0.6

Advances in Gerontology Pub Date : 2025-03-19 DOI: 10.1134/S2079057025600090

A. N. Khokhlov

引用次数: 0