NUCLEAR MEDICINE REVIEW最新文献

{"title":"Incidental detection of COVID-19 associated pneumonia by thyroid scintigraphy.","authors":"Mehrosadat Alavi,&nbsp;Fariba Jafari","doi":"10.5603/NMR.2021.0026","DOIUrl":"https://doi.org/10.5603/NMR.2021.0026","url":null,"abstract":"<p><p>This report presents a case of a 49-year-old woman with complaint of sore throat and front neck pain, who referred to a hospital for thyroid scan due to suppressed TSH level (0.005 mU/L). Diffuse and bilateral lungs uptake in the scan was noticed incidentally. The patient had positive history of COVID-19 symptoms. Multifocal and bilateral ground-glass opacities (GGOs) in both lungs were compatible with typical features of lung involvement in COVID-19-associated pneumonia.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer and PET Imaging.","authors":"Ismet Sarikaya","doi":"10.5603/NMR.2021.0004","DOIUrl":"10.5603/NMR.2021.0004","url":null,"abstract":"<p><p>Breast cancer is the most common malignancy in women and among the most common indications of oncologic positron emission tomography (PET) studies. In this review article, updated anatomical, pathological, and clinical information about breast cancer were provided for Nuclear Medicine physicians to better understand breast cancer and interpret PET images and a review of the literature on the use of PET imaging in breast cancer was summarized.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of [18F]FDG myocardial uptake in oncology patients as a predictor of myocardial ischaemia on stress myocardial perfusion imaging.","authors":"Ahmed Fathala,&nbsp;Abdulaziz Alsugair,&nbsp;Moheieldin Abouzied,&nbsp;Ahmed Almuhaideb","doi":"10.5603/NMR.2021.0015","DOIUrl":"https://doi.org/10.5603/NMR.2021.0015","url":null,"abstract":"<p><strong>Background: </strong>There is variable cardiac uptake observed on oncological ¹⁸F-fludeoxyglucose ([¹⁸F]FDG) positron emission/computed tomography (PET/CT). The main purpose of this study is to evaluate patterns of overnight fasting myocardial [¹⁸F]FDG uptake in oncological PET/CT and analyse the relationship between myocardial [¹⁸F]FDG uptake and myocardial ischaemia on stress single-photon emission CT (SPECT) myocardial perfusion imaging (MPI).</p><p><strong>Material and methods: </strong>A total of 362 subjects underwent both oncological PET/CT and stress SPECT MPI within 3 months of each other. Subjects with focal-mass-like [¹⁸F]FDG myocardial uptake raising the suspicion of cardiac metastasis and subjects with coronary artery disease (CAD) were excluded. The myocardial [18F]FDG uptake was classified into four patterns.</p><p><strong>Results: </strong>Abnormal SPECT MPI was noted in 91 (25%) patients; 220 (61%) patients had completely absent [18F]FDG uptake, 80 (22%) had diffuse [¹⁸F]FDG uptake, 39 (11%) had focal on diffuse [¹⁸F]FDG uptake, and 23 (6%) had focal or regional myocardial [¹⁸F]FDG uptake, the regional [¹⁸F]FDG myocardial uptake was the most predictive of myocardial ischaemia on SPECT MPI, and there were positive associations between age, sex, hypertension, tobacco smoking, hypercholesterolemia, and left ventricular ejection, a fair agreement was noted between the focal or regional FDG uptake and presence of ischaemia on SPECT, K = 0.394 (95% CI 0.164 to 0.189).</p><p><strong>Conclusions: </strong>Based on the presented findings, the physiological myocardial [¹⁸F]FDG uptake in fasting oncology patients is variable. The regional myocardial [¹⁸F]FDG uptake pattern is the most frequent pattern associated with myocardial ischaemia on stress SPECT MPI, however, the agreement between regional FDG uptake and presence of ischaemia on SPECT is fair.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39303506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of COVID-19 associated pneumonia by [99mTc]UBI scintigraphy.","authors":"Fariba Jafari,&nbsp;Mehrosadat Alavi","doi":"10.5603/NMR.2021.0025","DOIUrl":"https://doi.org/10.5603/NMR.2021.0025","url":null,"abstract":"<p><p>A 31-year-old woman who had multiple orthopedic surgeries on the left lower limb and recently suffered from pain and redness in the lateral left lower thigh was referred to the hospital to rule out osteomyelitis by [99mTc]UBI scintigraphy. Except soft tissue inflammation in the mentioned region, the scan showed significant and diffuse both lungs uptake incidentally. The patient had experienced symptoms of COVID-19 disease recently. Chest HRCT scan also revealed multiple segmental ground-glass opacities (GGOs) which were typical features for lung involvement of COVID-19 associated pneumonia.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Findings in [99mTc]MAA SPECT/CT in the diagnosis and follow-up of pulmonary embolism after infection by SARS-CoV-2 (COVID-19).","authors":"Marylin Acuña Hernandez,&nbsp;Tatiana Morales Avellaneda,&nbsp;Jorge Andres Narvaez Gomez,&nbsp;Liset Sanchez Orduz","doi":"10.5603/NMR.2021.0029","DOIUrl":"https://doi.org/10.5603/NMR.2021.0029","url":null,"abstract":"<p><p>SARS-CoV-2 (COVID-19) infection is a current public health problem that has been shown to cause multiple complications, including pulmonary thromboembolism. The first presented case is a 59-year-old woman with a history of COPD, paroxysmal atrial fibrillation and COVID-19 infection in September 2020, consultation in December 2020 for atypical chest pain with suspected PE, AngioCT of pulmonary vessels was performed negative for emboli, subsequently [99mTc]Tc MAA SPECT/CT was indicated with a report of multiple triangular defects concerning acute pulmonary thromboembolism. A second case is a 70-year-old man with a history of dyslipidaemia, presented COVID-19 infection in September 2020 with a complication of PE with involvement of the left pulmonary artery, followed by [99mTc]Tc MAA SPECT/CT report multiple triangular and not triangles defects concerning pulmonary thromboembolism with signs of reperfusion.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Findings in bone scintigraphy with [99mTc] Tc-MDP of a mandibular ameloblastic carcinoma.","authors":"Liliana Patricia Torres, Marylin Acuña Hernandez, Tatiana Morales Avellaneda, Andrés Ilich González Ramírez","doi":"10.5603/NMR.2021.0005","DOIUrl":"10.5603/NMR.2021.0005","url":null,"abstract":"","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of [18F]FDG PET-CT in the follow-up of surgically treated oral tongue squamous cell carcinoma: single centre cohort analysis on 87 patients.","authors":"Marco Ravanelli,&nbsp;Alberto Grammatica,&nbsp;Guido Squassina,&nbsp;Francesco Bertagna,&nbsp;Domenico Albano,&nbsp;Davide Lancini,&nbsp;Paolo Bosio,&nbsp;Angelo Zigliani,&nbsp;Giorgio Maria Agazzi,&nbsp;Roberto Maroldi,&nbsp;Piero Nicolai,&nbsp;Raffaele Giubbini,&nbsp;Cesare Piazza,&nbsp;Davide Farina","doi":"10.5603/NMR.2021.0016","DOIUrl":"https://doi.org/10.5603/NMR.2021.0016","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the diagnostic performance of [¹⁸F]fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG-PET/CT) scan in detecting local recurrences in patients with surgically treated oral tongue squamous cell cancer (OTSCC).</p><p><strong>Material and methods: </strong>Eighty-seven patients who had undergone surgery for OTSCC were monitored clinically and [¹⁸F]FDGPET/CT and magnetic resonance (MR). PET uptakes were classified as functional (Type A), suspicious (Type B), or highly suggestive of local recurrence (Type C). A multidisciplinary team (MDT) evaluated case-by-case the surveillance strategy based on PET uptake.</p><p><strong>Results: </strong>Fifty-nine patients presented FDG-PET uptake during follow-up: this report was significantly more frequent in patients who received flap reconstruction than in those without (73% vs 50%; p = 0.05). In 13 patients with Type A (n = 1), Type B (n = 9), and Type C (n = 3) uptakes an additional MR was considered preferable and discovered recurrence in 12.PET-CT had 9 true positives, 17 false positives, 71 true negatives, and no false-negative, resulting in sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of 100%, 80.7%, 34.6%, and 100%.</p><p><strong>Conclusions: </strong>The present results demonstrated a change in diagnostic strategy, as decided by the MDT, in about one-fifth of patients. The results should prompt in designing a rational surveillance schedule in surgically treated OTSCC.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39303507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[99mTc]MIBI scintigraphy in a patient with thyroid follicular neoplasm: a case report and review of literature.","authors":"Mohsen Arabi,&nbsp;Hanieh Zamani,&nbsp;Masume Soltanabadi,&nbsp;Leila Kalhor","doi":"10.5603/NMR.2021.0028","DOIUrl":"https://doi.org/10.5603/NMR.2021.0028","url":null,"abstract":"<p><p>[99mTc]MIBI thyroid scintigraphy is a useful tool to differentiate benign from malignant thyroid nodules. This report aims to show the diagnostic performance of [99mTc]MIBI scintigraphy used in an 83-year-old woman who had a thyroidectomy about 7 years ago. She had a mass of thyroid which was very large, non-homogenous and painless. [99mTc]MIBI scintigraphy could be a pre-surgical method to investigate the follicular nodules and predicting the malignant form of thyroid nodules. Also, it will provide tissue information for [99mTc]MIBI images in thyroid lesions.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age, BMI and diabetes as independent predictors of brain hypoperfusion.","authors":"Zita Képes, Ferenc Nagy, Ádám Budai, Sándor Barna, Regina Esze, Sándor Somodi, Miklós Káplár, Ildikó Garai, József Varga","doi":"10.5603/NMR.2021.0002","DOIUrl":"10.5603/NMR.2021.0002","url":null,"abstract":"<p><strong>Background: </strong>Cerebral blood flow abnormalities are supposed to be potential risk factors for developing cognitive dysfunction in the general population. Aging, obesity and type 2 diabetes mellitus are associated with perfusion abnormalities leading to cognitive impairment, neurodegeneration and future development of dementia. In our study, we aimed at identifying independent factors that contribute to the appearance of regional brain perfusion changes besides those that are already known.</p><p><strong>Material and methods: </strong>Forty-three type 2 diabetic and twenty-six obese patients were enrolled. After the intravenous administration of 740 MBq 99mTc-hexamethylpropylene amine oxime (HMPAO), all subjects underwent brain perfusion SPECT imaging applying AnyScan S Flex dual-head gamma camera (Mediso, Hungary). Using Philips Achieva 3T scanner brain resting-state functional MRI was also performed. The SPECT and MRI images were co-registered and transformed to the MNI152 atlas space so that data of the following standard volumes of interest (VOIs) could be obtained: frontal lobe, parietal lobe, temporal lobe, occipital lobe, limbic region, cingulate, insula, basal ganglia, cerebrum, limbic system and brain stem. Using the SPSS 25 statistical software package, general linear regression analysis, Student's t-test, and Mann-Whitney U-test were applied for statistical analyses.</p><p><strong>Results: </strong>Multivariate linear analysis identified that BMI and age are significantly (p < 0.0001) associated with perfusion, and patient group was slightly above threshold (p = 0.0524). We also found that the presence of diabetes was an independent significant predictor of normalized regional brain perfusion only in the insula (p < 0.001). Other independent predictors of normalized regional brain perfusion were: age in the insula (p < 0.001) and in the limbic region (p < 0.01), and BMI in the brain stem (p < 0.01).</p><p><strong>Conclusions: </strong>Age and BMI proved to be general, and diabetes regional predictor of brain hypoperfusion. BMI appeared to be a novel factor affecting brain perfusion. In one specific region, the insula, we detected a difference between the obese and the diabetic group. These findings may be significant in the understanding of the development of cognitive impairment in metabolic diseases.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental finding of a dermoid cyst in a whole-body iodine scan: importance of using [131I]SPECT/CT in the differentiated thyroid carcinoma.","authors":"Hadis Mohammadzadeh Kosari,&nbsp;Seyed Rasoul Zakavi,&nbsp;Somayeh Barashki,&nbsp;Hesamoddin Roustaei Firouzabad,&nbsp;Saeedeh Ataei Nakhaei,&nbsp;Kamran Aryana","doi":"10.5603/NMR.2021.0023","DOIUrl":"https://doi.org/10.5603/NMR.2021.0023","url":null,"abstract":"<p><p>A 33-year-old female with a history of total thyroidectomy for papillary thyroid carcinoma was referred to the nuclear medicine department for ablative radioiodine therapy. Post ablation scan showed an area of intense iodine uptake on the left side of the pelvic region, corresponding to the large well-defined heterogeneous mass in the left ovary in the SPECT/CT images. The radiologic features of this lesion were compatible with a dermoid cyst, previously unrecognized. Eventually, the lesion was laparoscopically removed, and a typical dermoid cyst was confirmed through histopathologic assessment.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}