World Journal of Acupuncture-Moxibustion最新文献

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World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Filiform Needle 世界针灸学会联合会(WFAS)针灸技术基准:丝状针
IF 0.6 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-07-01 DOI: 10.1016/j.wjam.2024.05.001
Liang ZHOU (周亮) , Si-qi ZHANG (张斯琦) , Meng FANG (方梦) , Gui-rong DONG (东贵荣) , Hong-sheng DONG (东红升)
{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Filiform Needle","authors":"Liang ZHOU (周亮) ,&nbsp;Si-qi ZHANG (张斯琦) ,&nbsp;Meng FANG (方梦) ,&nbsp;Gui-rong DONG (东贵荣) ,&nbsp;Hong-sheng DONG (东红升)","doi":"10.1016/j.wjam.2024.05.001","DOIUrl":"10.1016/j.wjam.2024.05.001","url":null,"abstract":"<div><p>On December 31, 2023, World Federation of Acupuncture-Moxibustion Societies (WFAS) officially issued <em>Technical Benchmark of Acupuncture and Moxibustion: Filiform Needle.</em> This technical benchmark clarifies terms and definitions, operating procedures and requirements, safety requirements, etc. The promulgation and implementation of this technical benchmark would provide a standard for acupuncture practitioners to apply filiform needle in clinical practice, and may play a positive role in the safe use and promotion of filiform needle.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 231-236"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000370/pdfft?md5=70c999909f003d5dd46334e25663b518&pid=1-s2.0-S1003525724000370-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Cupping 世界针灸学会联合会(WFAS)针灸技术基准:拔罐
IF 0.6 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-07-01 DOI: 10.1016/j.wjam.2024.07.002
Dan LI (李丹) , Yu-Jia LI (李彧嘉) , Yi GUO (郭义) , Xue ZHAO (赵雪) , Xiao-Dong WU (武晓冬) , Xiao-Ning YUAN (袁晓宁) , Ono YASUO (小野泰生) , Jia-Yin ZHANG (张嘉殷) , Yu-Fan ZHOU (周煜凡) , Yi YANG (杨毅) , Tian-Yi ZHAO (赵天易) , Bo CHEN (陈波) , Zi-Qi WANG (王子淇) , Hao-Yang WEN (闻昊阳) , Tian-Cong FU (付天聪) , Ze-Lin CHEN (陈泽林) , Jun JIN (金军)
{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Cupping","authors":"Dan LI (李丹) ,&nbsp;Yu-Jia LI (李彧嘉) ,&nbsp;Yi GUO (郭义) ,&nbsp;Xue ZHAO (赵雪) ,&nbsp;Xiao-Dong WU (武晓冬) ,&nbsp;Xiao-Ning YUAN (袁晓宁) ,&nbsp;Ono YASUO (小野泰生) ,&nbsp;Jia-Yin ZHANG (张嘉殷) ,&nbsp;Yu-Fan ZHOU (周煜凡) ,&nbsp;Yi YANG (杨毅) ,&nbsp;Tian-Yi ZHAO (赵天易) ,&nbsp;Bo CHEN (陈波) ,&nbsp;Zi-Qi WANG (王子淇) ,&nbsp;Hao-Yang WEN (闻昊阳) ,&nbsp;Tian-Cong FU (付天聪) ,&nbsp;Ze-Lin CHEN (陈泽林) ,&nbsp;Jun JIN (金军)","doi":"10.1016/j.wjam.2024.07.002","DOIUrl":"10.1016/j.wjam.2024.07.002","url":null,"abstract":"<div><p><em>World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Cupping</em>, developed under the leadership of Tianjin University of Traditional Chinese Medicine, was approved by WFAS. This technical benchmark was issued on October 9, 2023, and implemented on December 31, 2023. The main contents include the scope, normative references, terms and definitions, procedures and rules, and safety. This article focuses on the above contents, an outlook on the application, popularization, and update plan of this technical benchmark is proposed.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 222-226"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S100352572400045X/pdfft?md5=4cd596cba7d8e5fe6b692dc48abad509&pid=1-s2.0-S100352572400045X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141689317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Practice Guideline on Acupuncture and Moxibustion: Adult Major Depressive Disorder (Mild-Moderate Degree): Determination of clinical questions 确定临床问题
IF 0.6 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-07-01 DOI: 10.1016/j.wjam.2024.07.004
Han TANG (汤翰) , Qi FAN (范琦) , Li-hua GUO (郭丽花) , Yu-qing ZHANG (张誉清) , Yi-xuan FENG (丰逸轩) , Yu-qing XU (徐玉芹) , Hong-jun KUANG (匡泓俊) , Yun-hong YANG (杨云虹) , Yi GOU (缑漪) , Hong ZHAO (赵宏)
{"title":"Clinical Practice Guideline on Acupuncture and Moxibustion: Adult Major Depressive Disorder (Mild-Moderate Degree): Determination of clinical questions","authors":"Han TANG (汤翰) ,&nbsp;Qi FAN (范琦) ,&nbsp;Li-hua GUO (郭丽花) ,&nbsp;Yu-qing ZHANG (张誉清) ,&nbsp;Yi-xuan FENG (丰逸轩) ,&nbsp;Yu-qing XU (徐玉芹) ,&nbsp;Hong-jun KUANG (匡泓俊) ,&nbsp;Yun-hong YANG (杨云虹) ,&nbsp;Yi GOU (缑漪) ,&nbsp;Hong ZHAO (赵宏)","doi":"10.1016/j.wjam.2024.07.004","DOIUrl":"10.1016/j.wjam.2024.07.004","url":null,"abstract":"<div><p>Determining clinical questions is fundamental to the development of clinical practice guidelines (CPGs), which bridges the initial phases and the final recommendations. It is essential for evidence retrieval and the formulation of recommendations. The scientific rigor and precision in determination of clinical questions directly influence the future implementation and applicability of guidelines. In 2020, the World Federation of Acupuncture-Moxibustion Societies initiated the project of clinical practice guideline on acupuncture and moxibustion for adult major depressive disorder (mild-moderate degree) to address clinical and medical decision-making issues in acupuncture treatment for adult mild to moderate major depressive disorder. This CPG provides systematic recommendations based on clinical evidence, patient values, and other factors, aiding decision-makers, clinicians, and patients in selecting appropriate interventions. This paper discusses and analyzes the determination process of clinical questions, and the related issues during the development of this guideline, aiming to provide a reference for determining clinical questions and developing CPGs in the field of acupuncture and exploring more scientific tools and methods for determining clinical questions in future CPGs.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 246-251"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000473/pdfft?md5=dbe15f05915b8f3b07cbaac0090ee4de&pid=1-s2.0-S1003525724000473-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
World Federation of Acupuncture-Moxibustion Societies (WFAS) Clinical Practice Guideline on Acupuncture and Moxibustion: Allergic Rhinitis recommendation summaries 世界针灸学会联合会(WFAS)针灸临床实践指南:过敏性鼻炎建议摘要
IF 0.6 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-07-01 DOI: 10.1016/j.wjam.2024.06.002
Shi-hao DU (杜世豪) , Jing LIU (刘静) , Sheng CHEN (陈晟) , Shan-ze WANG (王舢泽) , Guan-qun WANG (王冠群) , Shuo DU (杜朔) , Xiao-long XIE (解小龙) , Bi-hui PENG (彭碧辉) , Wei GUO (郭玮) , Chao YANG (杨超) , Ji-ping ZHAO (赵吉平)
{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Clinical Practice Guideline on Acupuncture and Moxibustion: Allergic Rhinitis recommendation summaries","authors":"Shi-hao DU (杜世豪) ,&nbsp;Jing LIU (刘静) ,&nbsp;Sheng CHEN (陈晟) ,&nbsp;Shan-ze WANG (王舢泽) ,&nbsp;Guan-qun WANG (王冠群) ,&nbsp;Shuo DU (杜朔) ,&nbsp;Xiao-long XIE (解小龙) ,&nbsp;Bi-hui PENG (彭碧辉) ,&nbsp;Wei GUO (郭玮) ,&nbsp;Chao YANG (杨超) ,&nbsp;Ji-ping ZHAO (赵吉平)","doi":"10.1016/j.wjam.2024.06.002","DOIUrl":"10.1016/j.wjam.2024.06.002","url":null,"abstract":"<div><p><em>Clinical Practice Guideline on Acupuncture and Moxibustion: Allergic Rhinitis</em> was revised and released by the Standards Working Committee of World Federation of Acupuncture-Moxibustion Societies (WFAS) on October 9, 2023. This is the first clinical practice guideline (CPG) on acupuncture and moxibustion for allergic rhinitis approved by an international academic organization, which provides evidence-based recommendations and the practical therapeutic protocols for acupuncture practitioners globally. This CPG was developed by following Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) methodology, and the principles of the <em>World Health Organization Handbook for Guideline Development</em>. The members in the guideline development group (GDG) were from different countries, with different professions, and they played a critical role in the development of clinical questions, recommendations, and therapeutic protocols. Recommendations are the core of a CPG and the direct answers to clinical questions, due to which this article focuses on the recommendations of this CPG. The recommendations were developed by using the modified Delphi method and the GRADE grid rules, based on the updated systematic reviews of clinical evidence. A total of 15 recommendations for 15 clinical questions were developed in this CPG, including one strong recommendation for intervention based on high-quality evidence, three conditional recommendations for either the intervention or the comparison based on very low quality of evidence, and 11 conditional recommendations for the intervention based on very low quality of evidence.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 179-188"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000400/pdfft?md5=1542d0cf363d1a4973fc623062daf986&pid=1-s2.0-S1003525724000400-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Electroacupuncture 世界针灸学会联合会(WFAS)针灸技术基准:电针
IF 0.6 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-07-01 DOI: 10.1016/j.wjam.2024.03.006
Pei-qi LI (李沛琦) , Si-jie DANG (党思杰) , Fan-lian LI (李凡莲) , Fei-hong CAI (蔡飞鸿) , Yu-chen ZHANG (张宇宸) , Yi-fan WU (吴一凡) , Jia-ni SHI (施嘉旎) , Jia-wei LI (李佳蔚) , Xin FU (傅昕) , Meng-hu GUO (郭梦虎) , Bin XIAO (肖彬) , Hua-yuan YANG (杨华元)
{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Electroacupuncture","authors":"Pei-qi LI (李沛琦) ,&nbsp;Si-jie DANG (党思杰) ,&nbsp;Fan-lian LI (李凡莲) ,&nbsp;Fei-hong CAI (蔡飞鸿) ,&nbsp;Yu-chen ZHANG (张宇宸) ,&nbsp;Yi-fan WU (吴一凡) ,&nbsp;Jia-ni SHI (施嘉旎) ,&nbsp;Jia-wei LI (李佳蔚) ,&nbsp;Xin FU (傅昕) ,&nbsp;Meng-hu GUO (郭梦虎) ,&nbsp;Bin XIAO (肖彬) ,&nbsp;Hua-yuan YANG (杨华元)","doi":"10.1016/j.wjam.2024.03.006","DOIUrl":"10.1016/j.wjam.2024.03.006","url":null,"abstract":"<div><p>World Federation of Acupuncture-Moxibustion Societies (WFAS) <em>Technical Benchmark of Acupuncture and Moxibustion: Electroacupuncture</em>, developed under the leadership of Shanghai University of Traditional Chinese Medicine, was approved by WFAS. This technical benchmark was issued on October 9, 2023, and implemented on December 31, 2023. The main contents include the scope, normative references, terms and definitions, acupuncture and moxibustion procedures and rules, and safety. This article focuses on the above contents. An outlook on the application, popularization, and update plan of this technical benchmark is proposed.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 227-230"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000163/pdfft?md5=b1c35b996585e78c596ee9ab984ebf54&pid=1-s2.0-S1003525724000163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The regulatory effects of electroacupuncture on type 2 innate lymphoid cell (ILC2) function and browning of white adipose tissue in obese rats 电针对肥胖大鼠 2 型先天性淋巴细胞(ILC2)功能和白色脂肪组织褐变的调节作用
IF 0.7 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-04-01 DOI: 10.1016/j.wjam.2024.03.004
Jian-kun CHEN (陈剑坤) , Yuan WU (吴苑) , Wen-zhen LI (李文珍) , Meng-fen HUANG (黄梦芬) , Bin HUANG (黄彬) , Chang-cai XIE (谢长才) , Ji-qiang LI (李际强) , Yue LU (卢月) , Yu CHEN (陈裕)
{"title":"The regulatory effects of electroacupuncture on type 2 innate lymphoid cell (ILC2) function and browning of white adipose tissue in obese rats","authors":"Jian-kun CHEN (陈剑坤) ,&nbsp;Yuan WU (吴苑) ,&nbsp;Wen-zhen LI (李文珍) ,&nbsp;Meng-fen HUANG (黄梦芬) ,&nbsp;Bin HUANG (黄彬) ,&nbsp;Chang-cai XIE (谢长才) ,&nbsp;Ji-qiang LI (李际强) ,&nbsp;Yue LU (卢月) ,&nbsp;Yu CHEN (陈裕)","doi":"10.1016/j.wjam.2024.03.004","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.004","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To observe the effects of electroacupuncture (EA) on type 2 innate lymphoid cell (ILC2) function in white adipose tissue (WAT) of high-fat diet (HFD)-induced obese rats to reveal the mechanism underlying weight loss.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Male Winstar rats (n=15) were randomly divided into control, HFD, and HFD+EA groups, with five rats in each group. An obesity model was established by feeding rats with a HFD. EA (2 Hz, 1 mA) was applied to “Zhongwan (CV12)” bilateral “Tianshu (ST25)” “Zusanli (ST36)” and “Sanyinjiao (SP6)” for 15 min, 7 days a week, for a total of 5 weeks. During EA treatment, the HFD group was fed a HFD, whereas rats in the control group were maintained on a normal diet. There was no intervention in either the control or the HFD groups. Body weight was measured weekly. Full-field adipocyte morphology, adipocyte volume, and the number of abdominal WAT were observed under a microscope after sectioning and hematoxylin and eosin staining. The levels of IL-5 (interleukin-5), IL-13 (interleukin-13), IL-33 (interleukin-33), and ST2 (growth stimulating gene 2 protein) in the WAT were assayed using enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction (RT-PCR). The expression levels of browning markers including PGC1α(peroxisome proliferator-activated receptor gamma coactivator 1-alpha), PPARγ (peroxisome proliferator-activated receptor gamma), PRDM16 (histone-lysine N-methyltransferase), and UCP1(uncoupling protein 1 in WAT were detected by western blot analysis and RT-PCR.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;After a 7-week induction period, rats in both the HFD and HFD+EA groups were 20% heavier than their initial weights before modeling (&lt;em&gt;P&lt;/em&gt;&lt;0.01, &lt;em&gt;P&lt;/em&gt;&lt;0.001). Following a 5-week EA intervention, the body mass and Lee index of obese rats were significantly reduced (&lt;em&gt;P&lt;/em&gt;&lt;0.05). The HE results showed that adipocytes in the HFD group displayed a significant increase in diameter and a decrease in number compared to the control group. However, in the HFD+EA group, white adipocytes exhibited reduced diameter and appeared more regular in shape. In the control group, the proportion of ILC2 was (86.53±2.55)%, whereas in the HFD group, it decreased to (73.62±2.52)%, indicating a significant reduction in ILC2 in the WAT of obese rats. Following EA treatment, the proportion of ILC2 was elevated to (80.54±4.25)%. This analysis revealed a significant decrease in the expression levels of IL-5, IL-13, IL-33, and ST2 in the WAT of obese rats in the HFD group; however, these levels increased after EA intervention. The mRNA levels of PPARγ, PGC1α, PRDM16, and protein levels of UCP1 were decreased in the HFD group (&lt;em&gt;P&lt;/em&gt;&lt;0.01, &lt;em&gt;P&lt;/em&gt;&lt;0.05, and &lt;em&gt;P&lt;/em&gt;&lt;0.001), and the trends were significantly reversed with EA manipulation (&lt;em&gt;P&lt;/em&gt;&lt;0.05). RT-PCR and western blotting results revealed that EA remarkably upregulated the mRNA expression of","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 138-146"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S100352572400014X/pdfft?md5=f63132e5b072fdac46937b944e21cffd&pid=1-s2.0-S100352572400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic effects of electroacupuncture at different sites on rats with neuropathic pain via the spinal Nrf2/HO-1 pathway 不同部位的电针通过脊髓 Nrf2/HO-1 通路对神经性疼痛大鼠的治疗效果
IF 0.7 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-04-01 DOI: 10.1016/j.wjam.2024.03.003
Liu CHEN (陈柳) , Hao-tian PAN (潘昊天) , Ya-nan ZHANG (张衙楠) , Lan DUO (多兰) , Xin DONG (董馨) , Gong-ming WANG (王功命) , Jia ZHOU (周嘉) , Ke WANG (王珂)
{"title":"Therapeutic effects of electroacupuncture at different sites on rats with neuropathic pain via the spinal Nrf2/HO-1 pathway","authors":"Liu CHEN (陈柳) ,&nbsp;Hao-tian PAN (潘昊天) ,&nbsp;Ya-nan ZHANG (张衙楠) ,&nbsp;Lan DUO (多兰) ,&nbsp;Xin DONG (董馨) ,&nbsp;Gong-ming WANG (王功命) ,&nbsp;Jia ZHOU (周嘉) ,&nbsp;Ke WANG (王珂)","doi":"10.1016/j.wjam.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.003","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;This study aimed to assess the effects of electroacupuncture (EA) at the contralateral, ipsilateral, or bilateral “Zusanli (ST36)” and “Yanglingquan(GB34)” on neuropathic pain caused by chronic contractile injury (CCI) and to explore the role of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway in the effects of EA.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Male Sprague-Dawley rats were subjected to the CCI model to induce neuropathic pain. A total of 45 rats were randomly divided into five groups (n = 9): sham, CCI, EA-Co (CCI + EA at contralateral acupoints), EA-Ip (CCI + EA at ipsilateral acupoints), and EA-Bi (CCI + EA at bilateral acupoints). The rats received EA treatment on day 8 after CCI, once every alternate day, for a total of eight times. The time courses of mechanical pain threshold (MWT), hind paw withdrawal latency (HWL), and sciatic functional index (SFI) were determined. The expression levels of 8-hydroxydeoxyguanosine (8-OHdG), glutathione (GSH), superoxide dismutase (SOD) activity, interleukin-6 (IL-6), interleukin-1 beta (IL-1β), and tumor necrosis factor factor-alpha (TNF-α) in the spinal cord were measured. The distribution of Nrf2, its expression of Nrf2 in both the cytosol and nucleus, and the protein levels of its downstream target genes, NQO1 and HO-1, were detected via double immunofluorescence staining and western blotting, respectively.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Following CCI, both MWT and HWL in the CCI group significantly decreased from day 14 after surgery (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). EA treatment exhibited significant antinociceptive effects induced by CCI by increasing the MWT and HWL values, especially bilateral EA (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). The SFI of the CCI group was significantly lower than that of the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). Only bilateral EA improved the SFI scores compared to the CCI group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). 8-OHdG levels in the spinal cord of the CCI group were significantly higher than those in the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05), whereas GSH levels and SOD activity in the spinal cord of the CCI group were significantly lower than those in the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001 and &lt;em&gt;P&lt;/em&gt; &lt; 0.01, respectively). Bilateral EA administration significantly downregulated 8-OHdG levels (&lt;em&gt;P&lt;/em&gt; &lt; 0.01) and upregulated GSH levels and SOD activity in the spinal cord (&lt;em&gt;P&lt;/em&gt; &lt; 0.01). CCI significantly enhanced the production of IL-1β, IL-6, and TNF-α in the spinal cord compared with that in the sham group (all &lt;em&gt;P&lt;/em&gt; &lt; 0.001). Meanwhile, the effects of EA were also accompanied by markedly decreased expression of IL-1β and IL-6 in the spinal cord (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). TNF-α levels were only decreased in the EA-Ip and EA-Bi groups compared with those in the CCI group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). Confocal microscopy revealed that Nrf2 was mainly localized in the neurons of the spinal cord. Notably, EA treatment enhanced nuclear translocation o","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 130-137"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000138/pdfft?md5=2fa15a4ff2867e50a02754551f58a05c&pid=1-s2.0-S1003525724000138-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcutaneous auricular vagus nerve stimulation: Clinical applications and mechanisms 经皮耳廓迷走神经刺激:临床应用和机制
IF 0.7 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-04-01 DOI: 10.1016/j.wjam.2024.03.007
Yu-zhengheng ZHANG (张煜郑姮) , Ning-yi ZOU (邹凝怿) , Pei-jing RONG (荣培晶) , Shao-yuan LI (李少源)
{"title":"Transcutaneous auricular vagus nerve stimulation: Clinical applications and mechanisms","authors":"Yu-zhengheng ZHANG (张煜郑姮) ,&nbsp;Ning-yi ZOU (邹凝怿) ,&nbsp;Pei-jing RONG (荣培晶) ,&nbsp;Shao-yuan LI (李少源)","doi":"10.1016/j.wjam.2024.03.007","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.007","url":null,"abstract":"","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 174-175"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000175/pdfft?md5=a5f047e287e6b0feafed1cd8350a8b0c&pid=1-s2.0-S1003525724000175-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of acupuncture for anisometropic amblyopia: A randomized clinical trial and potential mechanism 针灸治疗异向性弱视的效果:随机临床试验和潜在机制
IF 0.7 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-04-01 DOI: 10.1016/j.wjam.2024.04.005
Cui MA (马翠) , Jing JIA (贾静) , Yu-juan YE (叶钰娟) , Yan SUN (孙燕) , Xing-ke YAN (严兴科)
{"title":"Effect of acupuncture for anisometropic amblyopia: A randomized clinical trial and potential mechanism","authors":"Cui MA (马翠) ,&nbsp;Jing JIA (贾静) ,&nbsp;Yu-juan YE (叶钰娟) ,&nbsp;Yan SUN (孙燕) ,&nbsp;Xing-ke YAN (严兴科)","doi":"10.1016/j.wjam.2024.04.005","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.005","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To evaluate the effect of acupuncture on anisometropic amblyopia (AA) and explore its potential mechanism for children with AA.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Seventy-six children with monocular AA were randomized into a conventional treatment group and a combined treatment group of acupuncture and conventional treatment, with 38 patients in each group. In the conventional treatment group, on the base of patching regimen, the red flashing, grating and visual stimulation were delivered. Each approach lasted for 5 min per session and was given once every two days, three times a week, for 4 consecutive weeks. In the acupuncture-combined treatment group, on the base of the regimen of conventional treatment group, acupuncture was applied to Jingming (BL1), Cuanzhu (BL2), Fengchi (GB20) and Guangming (GB37), with needles retained for 20 min per session, once every two days, three times of intervention a week and for 4 consecutive weeks. Before and after treatment, the best corrected vision acuity (BCVA) was observed to evaluate the clinical effect in the two groups. Before treatment started, 15 patients with AA on left side were randomized selected from each group and the resting-state functional magnetic resonance imaging (rs-fMRI) was operated before and after treatment. Simultaneously, eight healthy children with normal visual acuity were recruited to be the normal control group and received one-time rs-fMRI scanning. Based on the activation likelihood estimation (ALE), the visual “what” pathway network was constructed. By analyzing the amplitude of low frequency fluctuation (ALFF) and the regional homogeneity (ReHo), the differences in the regional autonomous function activities in the key brain areas of the “what” pathway were compared among the three groups.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;(1) Clinical effect: After treatment, BCVA was (0.6 [0.5, 0.6]), higher than that (0.4 [0.3, 0.5]) before treatment, presenting the statistical difference (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) in the conventional treatment group. BCVA was (0.6 [0.6, 0.8]), higher than that (0.4 [0.4, 0.5]) before treatment, presenting the statistical difference (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) in the acupuncture-combined treatment group. BCVA in the acupuncture-combined treatment group was higher than that of the conventional treatment group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) after treatment. The total effective rate was 86.1% in the acupuncture-combined treatment group, higher than that (65.8%) of the conventional treatment group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). (2) Mechanism: ① ALFF: In comparison with the healthy control group, the ALFF in the primary visual cortex of the “what” pathway for AA children was reduced significantly (&lt;em&gt;P&lt;/em&gt; &lt; 0.05), and ALFF in the right fusiform gyrus and the right inferior temporal gyrus increased significantly when compared with the healthy children (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with that before treatment, there was no significant difference in the b","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 147-155"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000242/pdfft?md5=e5b7089ad137ede0f64833023992faa4&pid=1-s2.0-S1003525724000242-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of acupuncture and moxibustion as the adjuvant therapy on frozen-thawed embryo transfer: A network meta-analysis 针灸作为辅助疗法对冷冻解冻胚胎移植的影响:网络荟萃分析
IF 0.7 4区 医学
World Journal of Acupuncture-Moxibustion Pub Date : 2024-04-01 DOI: 10.1016/j.wjam.2024.04.003
Min-hui LUO (罗敏辉) , Yan TAN (谭艳) , Yao-chen ZUO (左耀辰) , Wen-ying SHI (石文英) , Xin WANG (王鑫) , Wei ZHANG (章薇)
{"title":"Effect of acupuncture and moxibustion as the adjuvant therapy on frozen-thawed embryo transfer: A network meta-analysis","authors":"Min-hui LUO (罗敏辉) ,&nbsp;Yan TAN (谭艳) ,&nbsp;Yao-chen ZUO (左耀辰) ,&nbsp;Wen-ying SHI (石文英) ,&nbsp;Xin WANG (王鑫) ,&nbsp;Wei ZHANG (章薇)","doi":"10.1016/j.wjam.2024.04.003","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.003","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the clinical effect of acupuncture- moxibustion as the adjuvant therapy on frozen-thawed embryo transfer (FET) using network meta-analysis.</p></div><div><h3>Methods</h3><p>In PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Wanfang database (WanFang), VIP database and Chinese Biomedical Literature Database (SinoMed), the randomized controlled trials (RCTs) of the adjuvant therapy of acupuncture-moxibustion for FET were retrieved, from database inception to April 1, 2021. Cochrane risk of bias assessment tool was used to screen and evaluate the quality of the included studies, and RevMan 5.3, GeMTC0.14.3 and Stata16.0 software were adopted to complete the network meta-analysis.</p></div><div><h3>Results</h3><p>Twenty-nine RCTs comprising 2880 patients were finally included, involving 17 interventions and 4 outcome measures. The results of network meta-analysis showed that the top three therapies under each outcome based on the magnitude of SUCRA values were: ① Clinical pregnancy rate (CPR, %): “transcutaneous electrical acupoint stimulation + herbal medicine” (76.4), “moxibustion + herbal medicine” (74.7), “acupuncture + moxibustion” (73.3); ②Biochemical pregnancy rate (BPR): “moxibustion + herbal medicine” (89.3), “acupuncture + moxibustion” (82.1), “acupuncture + herbal medicine” (78.7); ③Endometrial thickness: “acupoint injection + Western medicine” (87.2), auricular therapy (76.8), “acupuncture + herbal medicine” (73.5); ④Type A endometrial morphology rate: “acupoint injection + Western medicine ”(78.3), “moxibustion + herbal medicine” (58.0) and “acupuncture + moxibustion” (52.6).</p></div><div><h3>Conclusion</h3><p>The combined treatment of acupuncture-moxibustion was superior to single therapy for FET patients. The combined therapy of transcutaneous electrical acupoint stimulation and herbal medicine had the best effect for improving CPR, “moxibustion + herbal medicine” obtained the best average comprehensive effect, and “acupoint injection + Western medicine” was conductive to ameliorate the endometrial thickness and morphology. Due to the limitations of existing studies, more high-quality RCTs are needed in the future to further verify these conclusions.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 103-116"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000229/pdfft?md5=d72f9d2f6f562ea69b92a717b3bac413&pid=1-s2.0-S1003525724000229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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