World Journal of Acupuncture-Moxibustion最新文献

{"title":"Effects of moxibustion at different temperature on wound healing and apoptosis in rats with pressure ulcer based on PI3K/AKT/mTOR signal pathway","authors":"Hong PAN (潘虹) , Ying-Bo XI (葸英博) , Jin DING (丁劲) , Qin YIN (尹秦) , Hui-Qin XUE (薛慧琴) , Hai-Yu YUE (岳海玉)","doi":"10.1016/j.wjam.2025.02.003","DOIUrl":"10.1016/j.wjam.2025.02.003","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the effects of moxibustion on wound healing and evaluate whether the efficacy of moxibustion at different temperatures varies. Additionally, to explore the mechanism by which moxibustion regulates the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian rapamycin target protein (mTOR) signaling pathway on wound healing and cell apoptosis.</div></div><div><h3>Methods</h3><div>A total of 90 SPF-grade SD rats were randomly divided into six groups (15 rats per group): control group, model group, recombinant bovine basic fibroblast growth factor gel (rb-bFGF) group, moxibustion group A [temperature (42 ± 1) °C], moxibustion group B [temperature (45 ± 1) °C], and moxibustion group C [ temperature (48 ± 1) °C]. Except the control group, the interventions were conducted in the other groups with pressure ulcer induced by ischemia/reperfusion injury. In the control group, povidone-iodine was administered at the knee joint. In the model group, after povidone-iodine applied at the pressure ulcer, petroleum jelly gauze was bandaged. In the rb-bFGF group, after povidone-iodine applied at the pressure ulcer, rb-bFGF was smeared and petroleum jelly gauze was bandaged. In the moxibustion group A, the suspending moxibustion with moxa stick was delivered 3 cm to 5 cm above the ulcer. The paperless temperature recorder probe was placed on the wound surface where moxibustion was delivered, and the real-time temperature was monitored and adjusted, kept at (42 ± 1) °C. The moxibustion temperature was kept at (45 ± 1) °C in the moxibustion group B, and (48 ± 1) °C in the moxibustion group C. The intervention lasted 14 days in each group. The wound healing rates were compared on the 3, 5, 7 and 14 days after the first intervention among the 6 groups. After 14-day intervention respectively, the histopathological changes were observed with HE staining, apoptosis was detected with TUNEL method and flow cytometry; VEGF-A protein expression determined with immunohistochemistry; the contents of Interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and transforming growth factor-β (TGF-β) in serum with ELISA, and PI3K/AKT/mTOR related protein and mRNA expression was with Western blotting and qRT-PCR in wound tissues of each group.</div></div><div><h3>Results</h3><div>Regarding the intervention effects, (1) compared with the control group, the model group showed significant inflammatory infiltration in wound tissues, higher levels of cell apoptosis, and elevated serum levels of IL-6, TNF-α and TGF-β (<em>P</em> < 0.05); (2) compared with the model group, the rb-bFGF group and 3 moxibustion groups showed higher wound healing rates (<em>P</em> < 0.05), reduced inflammatory infiltration in the wound tissues, lower levels of cell apoptosis, and decreased serum levels of IL-6, TNF-α and TGF-β (<em>P</em> < 0.05). Among the moxibustion groups, group C showed significantly better results than group A (<em>P</em> < ","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 125-134"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shugan Tiaoshen needling method for postherpetic neuralgia: A randomized controlled trial","authors":"Yi-ling YANG (杨一玲) ,&nbsp;Wei-xuan ZHAO (赵伟璇) ,&nbsp;Jia-le LI (李嘉乐) ,&nbsp;Wei-qiang CHEN (陈伟强)","doi":"10.1016/j.wjam.2025.01.004","DOIUrl":"10.1016/j.wjam.2025.01.004","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the efficacy of <em>Shugan Tiaoshen</em> (liver-soothing and mind-regulating) needling method in the treatment of patients with postherpetic neuralgia (PHN).</div></div><div><h3>Methods</h3><div>A total of 66 patients with PHN were randomly divided into acupuncture group and control group, 33 cases in each one, by the random number table method. The acupuncture group received <em>Shugan Tiaoshen</em> needling method plus gabapentin, whereas the control group received the oral administration of gabapentin and sham acupuncture. Numerical Rating Scale (NRS), State-Trait Anxiety Inventory (STAI) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the pain condition, anxiety symptom and sleep quality. The effective rate and adverse events were also evaluated and recorded during the treatment.</div></div><div><h3>Results</h3><div>After eight weeks of treatment, the NRS scores of the two groups were significantly lower than those before treatment (<em>P</em> &lt; 0.05) at all time points, with statistically significant difference between the groups (<em>P</em> &lt; 0.05). The scores of STAI and PSQI of the acupuncture group were significantly lower than the scores before treatment (<em>P</em> &lt; 0.05). The scores of STAI for anxiety symptom and PSQI of the acupuncture group were significantly lower than the control group (<em>P</em> &lt; 0.05), and the effective rate of the acupuncture group was significantly higher than that of the control group (<em>P</em> &lt; 0.05). The incidence of adverse reactions in the acupuncture group was significantly lower than that in the control group (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div><em>Shugan Tiaoshen</em> needling method showed satisfactory efficacy in treating PHN, and could alleviate the pain, relieve the anxiety symptoms, promote sleep, and reduce the adverse reactions of gabapentin in patients with PHN.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 119-124"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of electroacupuncture on rats with primary dysmenorrhea based on microRNA expression spectrum and PI3K/Akt/mTOR signaling pathway","authors":"Si-an PAN (潘思安) ,&nbsp;Shao-hua WANG (汪少华) ,&nbsp;Han-yu YUAN (袁菡钰) ,&nbsp;Juan LI (李娟) ,&nbsp;Xiao XUE (薛晓) ,&nbsp;Zeng-hui YUE (岳增辉) ,&nbsp;Yu LIU (刘余)","doi":"10.1016/j.wjam.2025.03.002","DOIUrl":"10.1016/j.wjam.2025.03.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To investigate the effect of electroacupuncture (EA) on microRNA (miRNA) expression spectrum and PI3K/Akt/mTOR signaling pathway in uterine tissue of rats with primary dysmenorrhea (PDM), and to explore the potential mechanism of EA in the treatment of PDM.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Thirty female SD rats, weighted (200 ± 20) g were randomly divided into control group, model group and EA group, 10 rats in each group. By using subcutaneous injection of estradiol diphenhydrate combined with intraperitoneal injection of oxytocin, PDM models were established. Rats in the EA group received EA at “Sanyinjiao”(SP6) and “Guanyuan”(CV4) at dense waves and a frequency of 50 Hz, once a day, 20 min each time, for 10 consecutive days. After the 10-day intervention, samples were collected and transmission electron microscopy was used to observe the ultrastructural changes of the cells in uterine tissue in each group. With RNA-seq method, the changes of miRNA expression spectrum in rat uterine tissue were detected. Bioinformatics analysis such as GO functional annotation and KEGG pathway was performed according to differentially expressed miRNAs. Differentially expressed miRNAs were verified by qRT-PCR. Endometrial stromal cells were selected as the target cells and transfected; and they were divided into control group, NC mimics group, mimic miR-144–3p group, NC inhibitor group and inhibitor miR-144–3p group. The apoptosis was determined by using flow cytometrydetect apoptosis, the miRNA and protein expression of PI3K/Akt/mTOR signaling pathway were detected by qRT-PCR and Western blot in each group separately.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;1. Transmission electron microscope. (1) Control group: no obvious morphological changes in the uterine tissue. (2) Model group: fibroblasts in uterine tissue were irregular, the edema was presented in cellular cytoplasm, the nuclei were irregular and mitochondria swollen seriously; the rough endoplasmic reticulum was expanded moderately. (3) EA group: fibroblasts were spindle-shaped and pyknotic, the cytoplasm increased in electron density, the nuclei were slightly irregular and pyknotic, mitochondria were oval in shape, with little swelling and vacuolation; the rough endoplasmic reticulum was expanded slightly and retained, with a small amount of degranulation. 2. Compared with the control group, there were 26 differentially expressed miRNAs in the uterine tissue of rats with PDM. After EA intervention, the expression of miR-144–3p was significantly up-regulated. GO functional analysis of differentially expressed miRNAs in PDM rats after EA showed that the biological functions involved calcium transmembrane transporter activity, mitogen-activated protein kinase binding, epithelial cell migration, tissue migration, etc. 3. KEGG pathway analysis showed that PI3K/Akt signaling pathway, MAPK signaling pathway and calcium signaling pathway were enriched. Mimic miR-144-3p increased t","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 135-144"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficacy of electroacupuncture on pain and tolerance for unsedated colonoscopy: A study protocol for a prospective, randomized, sham-controlled trial","authors":"Yang ZHANG (张杨) ,&nbsp;Zhi-dan WANG (王志丹) ,&nbsp;Jie ZHANG (张杰) ,&nbsp;Shuang REN (任爽) ,&nbsp;Yue LIU (刘悦) ,&nbsp;Yun-xi LI (李赟溪) ,&nbsp;Xiao-yu MA (马晓宇) ,&nbsp;Xu WANG (汪旭) ,&nbsp;Hao SUN (孙皓) ,&nbsp;Ruo-shi LIU (刘若实)","doi":"10.1016/j.wjam.2025.03.003","DOIUrl":"10.1016/j.wjam.2025.03.003","url":null,"abstract":"<div><h3>Background</h3><div>Unsedated colonoscopy is an important method used for diagnosing colorectal cancer, but it can cause discomfort such as pain and bloating, as well as anxiety. At present, the relief is mainly achieved through methods such as changing positions and manual pressing, but the efficacy is limited. Hence alternative therapies for sedation and analgesia in unsedated colonoscopy warrant further study. Electroacupuncture (EA) can simplify the procedure of anesthesia and analgesia, while the efficacy of EA on unsedated colonoscopy remains unclear. Therefore, a well-designed randomized controlled trial is needed to demonstrate the potential efficacy of acupuncture in unsedated colonoscopy, particularly for pain relief.</div></div><div><h3>Methods</h3><div>In this prospective randomized sham-controlled trial, 105 eligible participants will be recruited and randomly assigned to either EA group (<em>n</em> = 35), sham EA group (<em>n</em> = 35), or control group (<em>n</em> = 35) in a 1:1:1 ratio. The EA group will receive acupuncture intervention on bilateral Hegu (LI4), Neiguan (PC6), Zusanli (ST36), and Shenmen (HT7), with LI4 and PC6 on both sides connected to the EA device. The sham EA group will received non transdermal needling on points of no meridian, and deliberately connect the needle to the incorrect output socket of EA device to block the stimulation. The needling will conducted from 30 min before the unsedated colonoscopy to the end of the colonoscopy, the whole retention time would be approximately 40 min. The participants in the control group will not receive any acupuncture intervention. All participants of the three groups will not receive any other treatment. Primary outcomes: Numerical Rating Scale (NRS) reported by participants and Face Pain Scale Revised (FPS-R) evaluated by observers of four areas of the participants during the unsedated colonoscopy. Secondary outcomes: tolerance reported by endoscopists, tolerance reported by participants, satisfaction reported by endoscopists, satisfaction reported by participants, adverse events during the unsedated colonoscopy, postoperative discomfort, unsedated colonoscopy smoothness (cecal insertion time, unwinding time, success rate of one-time intubation). Both intention-to-treat (ITT) and per-protocol (PP) analyses will be performed to assess the efficacy of EA.</div></div><div><h3>Discussion</h3><div>The trial will explore the efficacy of relieving pain, improving tolerability, and reducing undesirable adverse events of EA for unsedated colonoscopy. The results of this trial will provide sound evidence for promoting the clinical application of EA for unsedated colonoscopy.</div></div><div><h3>Trial registration</h3><div>ClinicalTrials.gov Identifier: ChiCTR2300069903, retrospectively registered on March 16, 2023.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 152-159"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and treatment strategy of acupuncture-moxibustion for advanced-age infertility in vitro fertilization and embryo transfer based on the temporal rhythm theory of traditional Chinese medicine","authors":"Shu Bee CHEN (曾炜美) ,&nbsp;Jing LIU (刘静) ,&nbsp;Xue-si HOU (侯学思) ,&nbsp;Li-kun YANG (杨丽鹍) ,&nbsp;Yi-ni SUN (孙旖旎) ,&nbsp;Shu-qi MI (米淑琦) ,&nbsp;Ji-ping ZHAO (赵吉平)","doi":"10.1016/j.wjam.2025.03.001","DOIUrl":"10.1016/j.wjam.2025.03.001","url":null,"abstract":"<div><div>The ability of natural conception decreases with age, leading many advanced-age women with fertility desire begin to attempt in vitro fertilization and embryo transfer (IVF-ET) technique nowadays. Traditional Chinese medicine (TCM) believes that human body undergoes periodic changes corresponding to the natural rhythms. Women exhibit distinct physiological lunar rhythms of the thoroughfare vessel and the conception vessel, as well as pathological rhythms during the menstrual cycle and IVF-ET cycle. Based on the theory of TCM temporal rhythm, this paper discusses the pathogenesis characteristics of infertility in advanced-age women at different stages. It believes that acupuncture intervention should comply with the following ideas: determining main acupoints based on disease differentiation, with a preference for the acupoints on the thoroughfare vessel, the conception vessel, spleen meridian and kidney meridian, as well as the back-<em>shu</em> points of the liver, spleen and kidney; determining the supplementary acupoints based on syndrome differentiation and symptoms; determining the supplementary acupoints based on time differentiation of lunar rhythm of the thoroughfare vessel and the conception vessel, and integrating both reinforcing and reducing techniques. During the process of intervention, the physical and mental states were balanced simultaneously.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 113-118"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomenclature and location of acupuncture points for laboratory animals Part 3: Mouse","authors":"China Association of Acupuncture and Moxibustion (中国针灸学会)","doi":"10.1016/j.wjam.2024.12.007","DOIUrl":"10.1016/j.wjam.2024.12.007","url":null,"abstract":"","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 160-162"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress on the mechanism of acupuncture-moxibustion in promoting the rehabilitation of sequelae of ischemic stroke","authors":"Chang-long ZHANG (张长龙) ,&nbsp;Yang LI (李阳) ,&nbsp;Fei XU (徐飞) ,&nbsp;Li-li SHANG (尚莉莉)","doi":"10.1016/j.wjam.2025.03.004","DOIUrl":"10.1016/j.wjam.2025.03.004","url":null,"abstract":"<div><div>Acupuncture-moxibustion can promote recovery from the sequelae of ischemic stroke. However, its mechanism of action has not yet been fully elucidated. This paper introduces the mechanism of acupuncture-moxibustion in alleviating rehabilitation of ischemic stroke sequelae. The regulatory mechanism of acupuncture-moxibustion was analyzed for limb movement disorders, cognitive impairment, depression, epilepsy, dysphagia, and insomnia after stroke from four aspects (promoting neuronal growth and cell proliferation, regulating cerebral blood flow, modulating neurochemicals, and suppressing cell apoptosis). This study provides theoretical support for the wide application of acupuncture-moxibustion in rehabilitation after ischemic stroke.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 96-102"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global trend in the research and development of acupuncture on low back pain during 1997 to 2023: A bibliometric analysis","authors":"Fang-hua ZHAO (赵芳华),&nbsp;Mei-ling SUN (孙美玲),&nbsp;Wen-yan SHI (石文艳),&nbsp;Hai-yan LI (李海燕)","doi":"10.1016/j.wjam.2025.01.003","DOIUrl":"10.1016/j.wjam.2025.01.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to analyze the current state and emerging trends in research articles related to acupuncture treatment for low back pain (LBP).</div></div><div><h3>Methods</h3><div>The Web of Science core database was utilized to retrieve relevant literature on acupuncture therapy for LBP from January 1, 1997, to August 29, 2023. Literature metrics analysis was conducted using Microsoft Excel, VOSviewer, SCImago Graphica, and Pajek. The analysis focused on annual publication volume, countries (regions), institutions, authors, journals, keywords, and references.</div></div><div><h3>Results</h3><div>A total of 1,434 papers on acupuncture treatment for LBP were identified, demonstrating a fluctuating growth trend over the past 25 years. Research in this field has been conducted in 57 countries, with the United States leading in terms of research output. Italy emerged as the country with the highest-quality publications, with an average citation frequency of 205.16 times. A total of 1,781 institutions contributed to research on acupuncture treatment for LBP, with Harvard University having the highest publication volume (cited 77 times). The number of authors contributing to this field reached 5,696, with In-Hyuk Ha having the highest publication count (31 papers) and Claudia-M. Witt is the most influential author (cited 2,699 times). Relevant research was published in 378 journals, with the <em>Journal of Alternative and Complementary Medicine</em> having the highest publication volume (77 papers), and Spine being the most influential journal (cited 3,420 times). A total of 3,854 keywords were identified, forming six main thematic clusters: care management, nerve stimulation, complementary medicine, pregnancy pain, rehabilitation research, and musculoskeletal pain. Twelve highly cited papers with citation frequencies ≥85 times were recognized, predominantly consisting of randomized controlled trials.</div></div><div><h3>Conclusion</h3><div>Over the past 25 years, the number of articles published on acupuncture for LPB has shown a fluctuating trend of growth; the distribution of countries (regions) and institutions that publish articles is scattered, mainly based on inter-regional cooperation, and international cooperation is still insufficient; Journals in alternative and integrative medicine category provide references for scholars to submit manuscripts and learn about the frontiers; Acupuncture is effective and economical in the treatment of pain, and it has been widely used in the treatment of low back pain. However, the difference in efficacy between acupuncture and sham acupuncture or placebo acupuncture remains controversial. Therefore, in the future, it is necessary to consider the selection of appropriate efficacy evaluation methods in clinical trials that reflect the therapeutic advantages of acupuncture.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 85-95"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to generate high-quality clinical evidence: Taking the study of acupuncture for chronic urticaria published in Annals of Internal Medicine as an example","authors":"Ren-hong WAN (万仁洪) ,&nbsp;Wei CAO (曹炜) ,&nbsp;Zi-hao ZOU (邹子豪) ,&nbsp;Shuai CHEN (陈帅) ,&nbsp;Si-jue CHEN (陈思珏) ,&nbsp;Hui ZHENG (郑晖) ,&nbsp;Ying LI (李瑛)","doi":"10.1016/j.wjam.2025.02.001","DOIUrl":"10.1016/j.wjam.2025.02.001","url":null,"abstract":"<div><div>High-quality clinical evidence is the basis of evidence-based medical practice. Acupuncture is the most widely used complementary and alternative medicine in the world. However, the improvement in the quality of acupuncture clinical research does not match the rapid increase in the number of acupuncture clinical research in recent years. At present, the number of high-quality acupuncture clinical research in the world remains low. Taking the trial of acupuncture for chronic spontaneous urticaria published in <em>Annals of Internal Medicine</em> as an example, this paper discusses the factors that contribute to producing high-quality clinical evidence for acupuncture from the aspects of selecting the topic of study, formulating the study method, designing the study plan, controlling the study process, writing the study report, and selecting the journal in the process of before, during, and after the research. It emphasizes the necessity to start from the benefit of global people's health, take practical clinical problems as guidance, cleverly choose the research entry point, and conduct high-quality research with clinical value. After the accomplishment of the study, the results must be faithfully described, the scientific conclusions accurately sublimated, and appropriate scientific journals selected for publication.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 109-112"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomenclature and location of acupuncture points for laboratory animals Part 2: Rat","authors":"China Association of Acupuncture and Moxibustion (中国针灸学会)","doi":"10.1016/j.wjam.2024.12.003","DOIUrl":"10.1016/j.wjam.2024.12.003","url":null,"abstract":"","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"35 2","pages":"Pages 163-165"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}