World Journal of Acupuncture-Moxibustion最新文献

{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Clinical Practice Guideline on Acupuncture and Moxibustion: Allergic Rhinitis recommendation summaries","authors":"Shi-hao DU (杜世豪) ,&nbsp;Jing LIU (刘静) ,&nbsp;Sheng CHEN (陈晟) ,&nbsp;Shan-ze WANG (王舢泽) ,&nbsp;Guan-qun WANG (王冠群) ,&nbsp;Shuo DU (杜朔) ,&nbsp;Xiao-long XIE (解小龙) ,&nbsp;Bi-hui PENG (彭碧辉) ,&nbsp;Wei GUO (郭玮) ,&nbsp;Chao YANG (杨超) ,&nbsp;Ji-ping ZHAO (赵吉平)","doi":"10.1016/j.wjam.2024.06.002","DOIUrl":"10.1016/j.wjam.2024.06.002","url":null,"abstract":"<div><p><em>Clinical Practice Guideline on Acupuncture and Moxibustion: Allergic Rhinitis</em> was revised and released by the Standards Working Committee of World Federation of Acupuncture-Moxibustion Societies (WFAS) on October 9, 2023. This is the first clinical practice guideline (CPG) on acupuncture and moxibustion for allergic rhinitis approved by an international academic organization, which provides evidence-based recommendations and the practical therapeutic protocols for acupuncture practitioners globally. This CPG was developed by following Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) methodology, and the principles of the <em>World Health Organization Handbook for Guideline Development</em>. The members in the guideline development group (GDG) were from different countries, with different professions, and they played a critical role in the development of clinical questions, recommendations, and therapeutic protocols. Recommendations are the core of a CPG and the direct answers to clinical questions, due to which this article focuses on the recommendations of this CPG. The recommendations were developed by using the modified Delphi method and the GRADE grid rules, based on the updated systematic reviews of clinical evidence. A total of 15 recommendations for 15 clinical questions were developed in this CPG, including one strong recommendation for intervention based on high-quality evidence, three conditional recommendations for either the intervention or the comparison based on very low quality of evidence, and 11 conditional recommendations for the intervention based on very low quality of evidence.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 179-188"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000400/pdfft?md5=1542d0cf363d1a4973fc623062daf986&pid=1-s2.0-S1003525724000400-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"World Federation of Acupuncture-Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Electroacupuncture","authors":"Pei-qi LI (李沛琦) ,&nbsp;Si-jie DANG (党思杰) ,&nbsp;Fan-lian LI (李凡莲) ,&nbsp;Fei-hong CAI (蔡飞鸿) ,&nbsp;Yu-chen ZHANG (张宇宸) ,&nbsp;Yi-fan WU (吴一凡) ,&nbsp;Jia-ni SHI (施嘉旎) ,&nbsp;Jia-wei LI (李佳蔚) ,&nbsp;Xin FU (傅昕) ,&nbsp;Meng-hu GUO (郭梦虎) ,&nbsp;Bin XIAO (肖彬) ,&nbsp;Hua-yuan YANG (杨华元)","doi":"10.1016/j.wjam.2024.03.006","DOIUrl":"10.1016/j.wjam.2024.03.006","url":null,"abstract":"<div><p>World Federation of Acupuncture-Moxibustion Societies (WFAS) <em>Technical Benchmark of Acupuncture and Moxibustion: Electroacupuncture</em>, developed under the leadership of Shanghai University of Traditional Chinese Medicine, was approved by WFAS. This technical benchmark was issued on October 9, 2023, and implemented on December 31, 2023. The main contents include the scope, normative references, terms and definitions, acupuncture and moxibustion procedures and rules, and safety. This article focuses on the above contents. An outlook on the application, popularization, and update plan of this technical benchmark is proposed.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 227-230"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000163/pdfft?md5=b1c35b996585e78c596ee9ab984ebf54&pid=1-s2.0-S1003525724000163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The regulatory effects of electroacupuncture on type 2 innate lymphoid cell (ILC2) function and browning of white adipose tissue in obese rats","authors":"Jian-kun CHEN (陈剑坤) ,&nbsp;Yuan WU (吴苑) ,&nbsp;Wen-zhen LI (李文珍) ,&nbsp;Meng-fen HUANG (黄梦芬) ,&nbsp;Bin HUANG (黄彬) ,&nbsp;Chang-cai XIE (谢长才) ,&nbsp;Ji-qiang LI (李际强) ,&nbsp;Yue LU (卢月) ,&nbsp;Yu CHEN (陈裕)","doi":"10.1016/j.wjam.2024.03.004","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.004","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To observe the effects of electroacupuncture (EA) on type 2 innate lymphoid cell (ILC2) function in white adipose tissue (WAT) of high-fat diet (HFD)-induced obese rats to reveal the mechanism underlying weight loss.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Male Winstar rats (n=15) were randomly divided into control, HFD, and HFD+EA groups, with five rats in each group. An obesity model was established by feeding rats with a HFD. EA (2 Hz, 1 mA) was applied to “Zhongwan (CV12)” bilateral “Tianshu (ST25)” “Zusanli (ST36)” and “Sanyinjiao (SP6)” for 15 min, 7 days a week, for a total of 5 weeks. During EA treatment, the HFD group was fed a HFD, whereas rats in the control group were maintained on a normal diet. There was no intervention in either the control or the HFD groups. Body weight was measured weekly. Full-field adipocyte morphology, adipocyte volume, and the number of abdominal WAT were observed under a microscope after sectioning and hematoxylin and eosin staining. The levels of IL-5 (interleukin-5), IL-13 (interleukin-13), IL-33 (interleukin-33), and ST2 (growth stimulating gene 2 protein) in the WAT were assayed using enzyme-linked immunosorbent assay and reverse transcription-polymerase chain reaction (RT-PCR). The expression levels of browning markers including PGC1α（peroxisome proliferator-activated receptor gamma coactivator 1-alpha）, PPARγ (peroxisome proliferator-activated receptor gamma), PRDM16 (histone-lysine N-methyltransferase), and UCP1（uncoupling protein 1 in WAT were detected by western blot analysis and RT-PCR.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;After a 7-week induction period, rats in both the HFD and HFD+EA groups were 20% heavier than their initial weights before modeling (&lt;em&gt;P&lt;/em&gt;&lt;0.01, &lt;em&gt;P&lt;/em&gt;&lt;0.001). Following a 5-week EA intervention, the body mass and Lee index of obese rats were significantly reduced (&lt;em&gt;P&lt;/em&gt;&lt;0.05). The HE results showed that adipocytes in the HFD group displayed a significant increase in diameter and a decrease in number compared to the control group. However, in the HFD+EA group, white adipocytes exhibited reduced diameter and appeared more regular in shape. In the control group, the proportion of ILC2 was (86.53±2.55)%, whereas in the HFD group, it decreased to (73.62±2.52)%, indicating a significant reduction in ILC2 in the WAT of obese rats. Following EA treatment, the proportion of ILC2 was elevated to (80.54±4.25)%. This analysis revealed a significant decrease in the expression levels of IL-5, IL-13, IL-33, and ST2 in the WAT of obese rats in the HFD group; however, these levels increased after EA intervention. The mRNA levels of PPARγ, PGC1α, PRDM16, and protein levels of UCP1 were decreased in the HFD group (&lt;em&gt;P&lt;/em&gt;&lt;0.01, &lt;em&gt;P&lt;/em&gt;&lt;0.05, and &lt;em&gt;P&lt;/em&gt;&lt;0.001), and the trends were significantly reversed with EA manipulation (&lt;em&gt;P&lt;/em&gt;&lt;0.05). RT-PCR and western blotting results revealed that EA remarkably upregulated the mRNA expression of","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 138-146"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S100352572400014X/pdfft?md5=f63132e5b072fdac46937b944e21cffd&pid=1-s2.0-S100352572400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic effects of electroacupuncture at different sites on rats with neuropathic pain via the spinal Nrf2/HO-1 pathway","authors":"Liu CHEN (陈柳) ,&nbsp;Hao-tian PAN (潘昊天) ,&nbsp;Ya-nan ZHANG (张衙楠) ,&nbsp;Lan DUO (多兰) ,&nbsp;Xin DONG (董馨) ,&nbsp;Gong-ming WANG (王功命) ,&nbsp;Jia ZHOU (周嘉) ,&nbsp;Ke WANG (王珂)","doi":"10.1016/j.wjam.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.003","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;This study aimed to assess the effects of electroacupuncture (EA) at the contralateral, ipsilateral, or bilateral “Zusanli (ST36)” and “Yanglingquan(GB34)” on neuropathic pain caused by chronic contractile injury (CCI) and to explore the role of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway in the effects of EA.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Male Sprague-Dawley rats were subjected to the CCI model to induce neuropathic pain. A total of 45 rats were randomly divided into five groups (n = 9): sham, CCI, EA-Co (CCI + EA at contralateral acupoints), EA-Ip (CCI + EA at ipsilateral acupoints), and EA-Bi (CCI + EA at bilateral acupoints). The rats received EA treatment on day 8 after CCI, once every alternate day, for a total of eight times. The time courses of mechanical pain threshold (MWT), hind paw withdrawal latency (HWL), and sciatic functional index (SFI) were determined. The expression levels of 8-hydroxydeoxyguanosine (8-OHdG), glutathione (GSH), superoxide dismutase (SOD) activity, interleukin-6 (IL-6), interleukin-1 beta (IL-1β), and tumor necrosis factor factor-alpha (TNF-α) in the spinal cord were measured. The distribution of Nrf2, its expression of Nrf2 in both the cytosol and nucleus, and the protein levels of its downstream target genes, NQO1 and HO-1, were detected via double immunofluorescence staining and western blotting, respectively.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;Following CCI, both MWT and HWL in the CCI group significantly decreased from day 14 after surgery (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). EA treatment exhibited significant antinociceptive effects induced by CCI by increasing the MWT and HWL values, especially bilateral EA (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). The SFI of the CCI group was significantly lower than that of the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). Only bilateral EA improved the SFI scores compared to the CCI group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). 8-OHdG levels in the spinal cord of the CCI group were significantly higher than those in the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05), whereas GSH levels and SOD activity in the spinal cord of the CCI group were significantly lower than those in the sham group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001 and &lt;em&gt;P&lt;/em&gt; &lt; 0.01, respectively). Bilateral EA administration significantly downregulated 8-OHdG levels (&lt;em&gt;P&lt;/em&gt; &lt; 0.01) and upregulated GSH levels and SOD activity in the spinal cord (&lt;em&gt;P&lt;/em&gt; &lt; 0.01). CCI significantly enhanced the production of IL-1β, IL-6, and TNF-α in the spinal cord compared with that in the sham group (all &lt;em&gt;P&lt;/em&gt; &lt; 0.001). Meanwhile, the effects of EA were also accompanied by markedly decreased expression of IL-1β and IL-6 in the spinal cord (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). TNF-α levels were only decreased in the EA-Ip and EA-Bi groups compared with those in the CCI group (&lt;em&gt;P&lt;/em&gt; &lt; 0.001). Confocal microscopy revealed that Nrf2 was mainly localized in the neurons of the spinal cord. Notably, EA treatment enhanced nuclear translocation o","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 130-137"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000138/pdfft?md5=2fa15a4ff2867e50a02754551f58a05c&pid=1-s2.0-S1003525724000138-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcutaneous auricular vagus nerve stimulation: Clinical applications and mechanisms","authors":"Yu-zhengheng ZHANG (张煜郑姮) ,&nbsp;Ning-yi ZOU (邹凝怿) ,&nbsp;Pei-jing RONG (荣培晶) ,&nbsp;Shao-yuan LI (李少源)","doi":"10.1016/j.wjam.2024.03.007","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.007","url":null,"abstract":"","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 174-175"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000175/pdfft?md5=a5f047e287e6b0feafed1cd8350a8b0c&pid=1-s2.0-S1003525724000175-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of acupuncture for anisometropic amblyopia: A randomized clinical trial and potential mechanism","authors":"Cui MA (马翠) ,&nbsp;Jing JIA (贾静) ,&nbsp;Yu-juan YE (叶钰娟) ,&nbsp;Yan SUN (孙燕) ,&nbsp;Xing-ke YAN (严兴科)","doi":"10.1016/j.wjam.2024.04.005","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.005","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To evaluate the effect of acupuncture on anisometropic amblyopia (AA) and explore its potential mechanism for children with AA.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Seventy-six children with monocular AA were randomized into a conventional treatment group and a combined treatment group of acupuncture and conventional treatment, with 38 patients in each group. In the conventional treatment group, on the base of patching regimen, the red flashing, grating and visual stimulation were delivered. Each approach lasted for 5 min per session and was given once every two days, three times a week, for 4 consecutive weeks. In the acupuncture-combined treatment group, on the base of the regimen of conventional treatment group, acupuncture was applied to Jingming (BL1), Cuanzhu (BL2), Fengchi (GB20) and Guangming (GB37), with needles retained for 20 min per session, once every two days, three times of intervention a week and for 4 consecutive weeks. Before and after treatment, the best corrected vision acuity (BCVA) was observed to evaluate the clinical effect in the two groups. Before treatment started, 15 patients with AA on left side were randomized selected from each group and the resting-state functional magnetic resonance imaging (rs-fMRI) was operated before and after treatment. Simultaneously, eight healthy children with normal visual acuity were recruited to be the normal control group and received one-time rs-fMRI scanning. Based on the activation likelihood estimation (ALE), the visual “what” pathway network was constructed. By analyzing the amplitude of low frequency fluctuation (ALFF) and the regional homogeneity (ReHo), the differences in the regional autonomous function activities in the key brain areas of the “what” pathway were compared among the three groups.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;(1) Clinical effect: After treatment, BCVA was (0.6 [0.5, 0.6]), higher than that (0.4 [0.3, 0.5]) before treatment, presenting the statistical difference (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) in the conventional treatment group. BCVA was (0.6 [0.6, 0.8]), higher than that (0.4 [0.4, 0.5]) before treatment, presenting the statistical difference (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) in the acupuncture-combined treatment group. BCVA in the acupuncture-combined treatment group was higher than that of the conventional treatment group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05) after treatment. The total effective rate was 86.1% in the acupuncture-combined treatment group, higher than that (65.8%) of the conventional treatment group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). (2) Mechanism: ① ALFF: In comparison with the healthy control group, the ALFF in the primary visual cortex of the “what” pathway for AA children was reduced significantly (&lt;em&gt;P&lt;/em&gt; &lt; 0.05), and ALFF in the right fusiform gyrus and the right inferior temporal gyrus increased significantly when compared with the healthy children (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with that before treatment, there was no significant difference in the b","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 147-155"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000242/pdfft?md5=e5b7089ad137ede0f64833023992faa4&pid=1-s2.0-S1003525724000242-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141163447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of acupuncture and moxibustion as the adjuvant therapy on frozen-thawed embryo transfer: A network meta-analysis","authors":"Min-hui LUO (罗敏辉) ,&nbsp;Yan TAN (谭艳) ,&nbsp;Yao-chen ZUO (左耀辰) ,&nbsp;Wen-ying SHI (石文英) ,&nbsp;Xin WANG (王鑫) ,&nbsp;Wei ZHANG (章薇)","doi":"10.1016/j.wjam.2024.04.003","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.003","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the clinical effect of acupuncture- moxibustion as the adjuvant therapy on frozen-thawed embryo transfer (FET) using network meta-analysis.</p></div><div><h3>Methods</h3><p>In PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), Wanfang database (WanFang), VIP database and Chinese Biomedical Literature Database (SinoMed), the randomized controlled trials (RCTs) of the adjuvant therapy of acupuncture-moxibustion for FET were retrieved, from database inception to April 1, 2021. Cochrane risk of bias assessment tool was used to screen and evaluate the quality of the included studies, and RevMan 5.3, GeMTC0.14.3 and Stata16.0 software were adopted to complete the network meta-analysis.</p></div><div><h3>Results</h3><p>Twenty-nine RCTs comprising 2880 patients were finally included, involving 17 interventions and 4 outcome measures. The results of network meta-analysis showed that the top three therapies under each outcome based on the magnitude of SUCRA values were: ① Clinical pregnancy rate (CPR, %): “transcutaneous electrical acupoint stimulation + herbal medicine” (76.4), “moxibustion + herbal medicine” (74.7), “acupuncture + moxibustion” (73.3); ②Biochemical pregnancy rate (BPR): “moxibustion + herbal medicine” (89.3), “acupuncture + moxibustion” (82.1), “acupuncture + herbal medicine” (78.7); ③Endometrial thickness: “acupoint injection + Western medicine” (87.2), auricular therapy (76.8), “acupuncture + herbal medicine” (73.5); ④Type A endometrial morphology rate: “acupoint injection + Western medicine ”(78.3), “moxibustion + herbal medicine” (58.0) and “acupuncture + moxibustion” (52.6).</p></div><div><h3>Conclusion</h3><p>The combined treatment of acupuncture-moxibustion was superior to single therapy for FET patients. The combined therapy of transcutaneous electrical acupoint stimulation and herbal medicine had the best effect for improving CPR, “moxibustion + herbal medicine” obtained the best average comprehensive effect, and “acupoint injection + Western medicine” was conductive to ameliorate the endometrial thickness and morphology. Due to the limitations of existing studies, more high-quality RCTs are needed in the future to further verify these conclusions.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 103-116"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000229/pdfft?md5=d72f9d2f6f562ea69b92a717b3bac413&pid=1-s2.0-S1003525724000229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture for endometriosis-associated infertility: Study protocol for a randomized controlled trial","authors":"Chu-ting WU (吴楚婷) ,&nbsp;Xiao-yan DONG (董晓燕) ,&nbsp;Xin-rong LI (李欣荣) ,&nbsp;Yang CAO (曹阳) ,&nbsp;Cai-mei HUANG (黄彩梅) ,&nbsp;Ming-yang LI (李铭旸) ,&nbsp;Jia-wei HU (胡佳玮) ,&nbsp;Yuan GAO (高源) ,&nbsp;Yu-ran LI (李语然) ,&nbsp;Huan-gan WU (吴焕淦) ,&nbsp;Chun-yan ZHANG (张春雁)","doi":"10.1016/j.wjam.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.01.001","url":null,"abstract":"<div><h3>Background</h3><p>Acupuncture has been proven to improve the pregnancy rate in infertile women. Endometriosis is a common cause of infertility. So far, there are no studies of the efficacy of acupuncture on endometriosis-associated infertility (EAI). Therefore, we will conduct a randomized controlled trial (RCT) to investigate whether acupuncture could have higher pregnancy rates in patients with EAI compared with sham acupuncture. The study protocol is reported in this paper.</p></div><div><h3>Methods/design</h3><p>The current trial is a multicenter randomized controlled study undergoing in Shanghai, China. About 224 eligible patients with EAI will be randomly assigned into the acupuncture group and the sham acupuncture group in a 1:1 ratio. In the acupuncture group, patients will be treated with acupuncture on Guanyuan (CV4), Zhongji (CV3), Zigong (EX-CA1), Xuehai (SP10), Zusanli (ST36), Sanyinjiao (SP6), and Taichong (LR3), twice a week, for 3 menstrual cycles, and 12 menstrual cycles will be followed up. The Park sham device will be used to perform non-transdermal acupuncture in the sham acupuncture group. The operation points will be located at 1.5 cm away beside these acupoints in the acupuncture group. The intervention period is the same as that in the acupuncture group. The primary outcome will be pregnancy rate. Secondary outcomes will include ultrasound results, cancer antigen 125 (CA125), anti-Müllerian hormone (AMH), sex hormones, and the Endometriosis Health Profile-5 (EHP-5). Outcomes will be collected at baseline, the end of treatment, and follow-up visits at 3, 6, and 12 menstrual cycles. All data, including major adverse events, will be recorded in electronic case report forms and analyzed using SPSS V.25.0.</p></div><div><h3>Discussion</h3><p>This study will help to evaluate whether acupuncture is effective in increasing the pregnancy rate of infertile women with endometriosis.</p></div><div><h3>Trial registration</h3><p><span>http://www.chictr.org.cn/</span><svg><path></path></svg> Identifier: ChiCTR2100047662. Registered 21 June 2021.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 156-162"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000102/pdfft?md5=0352d5350877917adedf8df77c7c0311&pid=1-s2.0-S1003525724000102-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex","authors":"Bai-le NING (宁百乐) ,&nbsp;Zhi-fang WANG (王志芳) ,&nbsp;Qing YANG (杨晴) ,&nbsp;Qian WU (吴倩) ,&nbsp;Qi-yue DENG (邓启粤) ,&nbsp;Jing GAO (高静) ,&nbsp;Wen FU (傅文) ,&nbsp;Ying DENG (邓颖) ,&nbsp;Bing-xin WU (吴炳鑫) ,&nbsp;Xi-chang HUANG (黄熙畅) ,&nbsp;Cong WANG (王聪) ,&nbsp;Wen-bin FU (符文彬)","doi":"10.1016/j.wjam.2024.03.002","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;A total of 150 healthy male adult SPF C57BL/6J mice were divided into five time-point groups: 1 h, 3 h, 6 h, 12 h and 24 h. Each time-point group was further divided into three groups: the model, scopolamine and acupuncture groups with 10 rats each. Rats were given forced swimming stimulation (15 min, once) before the intervention. A total of 200 healthy male adult specific pathogen-free (SPF) Sprague-Dawley (SD) rats were divided into 30 normal rats, and 170 modelling ones. A total of 90 rats were successfully modeled, and were randomly divided into three time-point groups: 1 h, 6 h and 24 h. And each time-point group was further divided into the normal, model, scopolamine, and acupuncture group. Chronic unpredictable mild stress (CUMS) combined with individual feeding was used to establish the depressed rat model. The sucrose preference test (SPT) and open field test (OFT) were used to evaluate the success of the model. There were 10 rats in each group. The acupuncture intervention was performed once for 20 min on “Baihui (GV20)”, “Yintang (GV29)”, “Hegu (LI4)”, and “Taichong (LR3)” without any other operations for the corresponding animals. Other groups were given corresponding medications. According to different time points, the forced swimming test (FST) was conducted in mice, and the FST and novelty-suppressed feeding test (NSFT) were measured in rats. Monoamine neurotransmitters (NE, DA, DOPAC, 5-HT, 5-HIAA, HVA) in the prefrontal cortex and hippocampus were detected with high performance liquid chromatography (HPLC). The expression of synapsin I, PSD95, p-mTOR, mTOR, and BDNF in the prefrontal cortex and hippocampus was determined by western blot.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;At the 1 h time point, compared with the model group, the immobility time was significantly decreased in the acupuncture group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At 3 h, 6 h, 12 h, and 24 h, compared with the model group, the immobility time was significantly reduced in both scopolamine and acupuncture groups (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 1 h time point, compared with the normal group, the immobility time of FST and the latency to feed were significantly increased in the model group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with the model group, the immobility time of FST showed a significant reduction in the acupuncture group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 6 h and 24 h time points, compared with the normal group, the immobility time of FST and the latency to feed were significantly increased in the model group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with the model group, the immobility time of FST was significantly decreased in the scopolamine and acupuncture groups (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 1 h and 24 h time points, compared with the normal group, the expression levels of 5-HT, 5-HIAA, NE, DA, DOPAC, and HVA of ","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 117-129"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000126/pdfft?md5=6c670c5323e0bbcfc187c273ef616d82&pid=1-s2.0-S1003525724000126-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of unilateral oculomotor nerve palsy after arachnoid cyst surgery in a Chinese boy","authors":"Jun WANG (汪军),&nbsp;Xiao-juan SHI (侍孝娟),&nbsp;Dan-dan LUO (骆丹丹)","doi":"10.1016/j.wjam.2024.03.009","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.009","url":null,"abstract":"<div><p>The paper reports a successful case of unilateral oculomotor palsy treated with acupuncture in a Chinese boy aged 5 years and 3 months. Filiform needles were applied for ptosis, ocular motility impairment and blurred vision of the left oculomotor palsy after arachnoid cyst surgery. Two stages of treatment with acupuncture were composed. Acupuncture in the first stage focused on resolving stasis, unblocking meridians and activating <em>qi</em> and blood circulation, especially at the acupoints around the eye, combined with the distal points (four gate points) to enhance <em>qi</em> movement and activate blood circulation, once daily. Besides, the western medicines for nerve nutrition were added. One month later, all the symptoms were alleviated, and the eyelid could be lifted. Then, the second stage of acupuncture started, during which, the western medicine for nerve nutrition was withdrawal, acupuncture was continued with the same acupoints as the first stage, once every two days. Besides, the thumb-tack needle was used to maintain the effect of filiform needle, and Zusanli (ST36) was added to replenish <em>qi</em> of spleen and stomach and promote circulation of meridians. Another month later, the lift of the left eyelid and the ocular motility were basically symmetrical to the right eye, and the left eye vision returned normal. Follow-up until the time of publication, the motility and function of the affected eye were basically the same as those of the healthy side. This case suggests that the staged intervention with acupuncture could be effective in child with unilateral oculomotor palsy after arachnoid cyst surgery and were acceptable for child. Further studies are needed to confirm the effect and mechanism of acupuncture intervention on postoperative oculomotor palsy.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 163-168"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000199/pdfft?md5=50970bf062f15eab5fc79bf6861ff0f0&pid=1-s2.0-S1003525724000199-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}