World Journal of Acupuncture-Moxibustion最新文献

{"title":"Acupuncture for endometriosis-associated infertility: Study protocol for a randomized controlled trial","authors":"Chu-ting WU (吴楚婷) ,&nbsp;Xiao-yan DONG (董晓燕) ,&nbsp;Xin-rong LI (李欣荣) ,&nbsp;Yang CAO (曹阳) ,&nbsp;Cai-mei HUANG (黄彩梅) ,&nbsp;Ming-yang LI (李铭旸) ,&nbsp;Jia-wei HU (胡佳玮) ,&nbsp;Yuan GAO (高源) ,&nbsp;Yu-ran LI (李语然) ,&nbsp;Huan-gan WU (吴焕淦) ,&nbsp;Chun-yan ZHANG (张春雁)","doi":"10.1016/j.wjam.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.01.001","url":null,"abstract":"<div><h3>Background</h3><p>Acupuncture has been proven to improve the pregnancy rate in infertile women. Endometriosis is a common cause of infertility. So far, there are no studies of the efficacy of acupuncture on endometriosis-associated infertility (EAI). Therefore, we will conduct a randomized controlled trial (RCT) to investigate whether acupuncture could have higher pregnancy rates in patients with EAI compared with sham acupuncture. The study protocol is reported in this paper.</p></div><div><h3>Methods/design</h3><p>The current trial is a multicenter randomized controlled study undergoing in Shanghai, China. About 224 eligible patients with EAI will be randomly assigned into the acupuncture group and the sham acupuncture group in a 1:1 ratio. In the acupuncture group, patients will be treated with acupuncture on Guanyuan (CV4), Zhongji (CV3), Zigong (EX-CA1), Xuehai (SP10), Zusanli (ST36), Sanyinjiao (SP6), and Taichong (LR3), twice a week, for 3 menstrual cycles, and 12 menstrual cycles will be followed up. The Park sham device will be used to perform non-transdermal acupuncture in the sham acupuncture group. The operation points will be located at 1.5 cm away beside these acupoints in the acupuncture group. The intervention period is the same as that in the acupuncture group. The primary outcome will be pregnancy rate. Secondary outcomes will include ultrasound results, cancer antigen 125 (CA125), anti-Müllerian hormone (AMH), sex hormones, and the Endometriosis Health Profile-5 (EHP-5). Outcomes will be collected at baseline, the end of treatment, and follow-up visits at 3, 6, and 12 menstrual cycles. All data, including major adverse events, will be recorded in electronic case report forms and analyzed using SPSS V.25.0.</p></div><div><h3>Discussion</h3><p>This study will help to evaluate whether acupuncture is effective in increasing the pregnancy rate of infertile women with endometriosis.</p></div><div><h3>Trial registration</h3><p><span>http://www.chictr.org.cn/</span><svg><path></path></svg> Identifier: ChiCTR2100047662. Registered 21 June 2021.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 156-162"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000102/pdfft?md5=0352d5350877917adedf8df77c7c0311&pid=1-s2.0-S1003525724000102-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The rapid antidepressant effect of acupuncture on two animal models of depression by increasing the expression of synaptic proteins in the prefrontal cortex","authors":"Bai-le NING (宁百乐) ,&nbsp;Zhi-fang WANG (王志芳) ,&nbsp;Qing YANG (杨晴) ,&nbsp;Qian WU (吴倩) ,&nbsp;Qi-yue DENG (邓启粤) ,&nbsp;Jing GAO (高静) ,&nbsp;Wen FU (傅文) ,&nbsp;Ying DENG (邓颖) ,&nbsp;Bing-xin WU (吴炳鑫) ,&nbsp;Xi-chang HUANG (黄熙畅) ,&nbsp;Cong WANG (王聪) ,&nbsp;Wen-bin FU (符文彬)","doi":"10.1016/j.wjam.2024.03.002","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;p&gt;To investigate the effect of acupuncture onset time and synaptic structure in two different models of depression.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;A total of 150 healthy male adult SPF C57BL/6J mice were divided into five time-point groups: 1 h, 3 h, 6 h, 12 h and 24 h. Each time-point group was further divided into three groups: the model, scopolamine and acupuncture groups with 10 rats each. Rats were given forced swimming stimulation (15 min, once) before the intervention. A total of 200 healthy male adult specific pathogen-free (SPF) Sprague-Dawley (SD) rats were divided into 30 normal rats, and 170 modelling ones. A total of 90 rats were successfully modeled, and were randomly divided into three time-point groups: 1 h, 6 h and 24 h. And each time-point group was further divided into the normal, model, scopolamine, and acupuncture group. Chronic unpredictable mild stress (CUMS) combined with individual feeding was used to establish the depressed rat model. The sucrose preference test (SPT) and open field test (OFT) were used to evaluate the success of the model. There were 10 rats in each group. The acupuncture intervention was performed once for 20 min on “Baihui (GV20)”, “Yintang (GV29)”, “Hegu (LI4)”, and “Taichong (LR3)” without any other operations for the corresponding animals. Other groups were given corresponding medications. According to different time points, the forced swimming test (FST) was conducted in mice, and the FST and novelty-suppressed feeding test (NSFT) were measured in rats. Monoamine neurotransmitters (NE, DA, DOPAC, 5-HT, 5-HIAA, HVA) in the prefrontal cortex and hippocampus were detected with high performance liquid chromatography (HPLC). The expression of synapsin I, PSD95, p-mTOR, mTOR, and BDNF in the prefrontal cortex and hippocampus was determined by western blot.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;At the 1 h time point, compared with the model group, the immobility time was significantly decreased in the acupuncture group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At 3 h, 6 h, 12 h, and 24 h, compared with the model group, the immobility time was significantly reduced in both scopolamine and acupuncture groups (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 1 h time point, compared with the normal group, the immobility time of FST and the latency to feed were significantly increased in the model group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with the model group, the immobility time of FST showed a significant reduction in the acupuncture group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 6 h and 24 h time points, compared with the normal group, the immobility time of FST and the latency to feed were significantly increased in the model group (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). Compared with the model group, the immobility time of FST was significantly decreased in the scopolamine and acupuncture groups (&lt;em&gt;P&lt;/em&gt; &lt; 0.05). At the 1 h and 24 h time points, compared with the normal group, the expression levels of 5-HT, 5-HIAA, NE, DA, DOPAC, and HVA of ","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 117-129"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000126/pdfft?md5=6c670c5323e0bbcfc187c273ef616d82&pid=1-s2.0-S1003525724000126-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of unilateral oculomotor nerve palsy after arachnoid cyst surgery in a Chinese boy","authors":"Jun WANG (汪军),&nbsp;Xiao-juan SHI (侍孝娟),&nbsp;Dan-dan LUO (骆丹丹)","doi":"10.1016/j.wjam.2024.03.009","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.009","url":null,"abstract":"<div><p>The paper reports a successful case of unilateral oculomotor palsy treated with acupuncture in a Chinese boy aged 5 years and 3 months. Filiform needles were applied for ptosis, ocular motility impairment and blurred vision of the left oculomotor palsy after arachnoid cyst surgery. Two stages of treatment with acupuncture were composed. Acupuncture in the first stage focused on resolving stasis, unblocking meridians and activating <em>qi</em> and blood circulation, especially at the acupoints around the eye, combined with the distal points (four gate points) to enhance <em>qi</em> movement and activate blood circulation, once daily. Besides, the western medicines for nerve nutrition were added. One month later, all the symptoms were alleviated, and the eyelid could be lifted. Then, the second stage of acupuncture started, during which, the western medicine for nerve nutrition was withdrawal, acupuncture was continued with the same acupoints as the first stage, once every two days. Besides, the thumb-tack needle was used to maintain the effect of filiform needle, and Zusanli (ST36) was added to replenish <em>qi</em> of spleen and stomach and promote circulation of meridians. Another month later, the lift of the left eyelid and the ocular motility were basically symmetrical to the right eye, and the left eye vision returned normal. Follow-up until the time of publication, the motility and function of the affected eye were basically the same as those of the healthy side. This case suggests that the staged intervention with acupuncture could be effective in child with unilateral oculomotor palsy after arachnoid cyst surgery and were acceptable for child. Further studies are needed to confirm the effect and mechanism of acupuncture intervention on postoperative oculomotor palsy.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 163-168"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000199/pdfft?md5=50970bf062f15eab5fc79bf6861ff0f0&pid=1-s2.0-S1003525724000199-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative analgesia with wrist- ankle acupuncture: Two case reports on wrist-ankle acupuncture combined with the interfascial plane block for emergency laparotomy","authors":"Yan LI (李燕) ,&nbsp;Zhe XU (徐哲) ,&nbsp;Feng-fei LIU (刘凤飞) ,&nbsp;Li YANG (杨丽) ,&nbsp;Zhi-xia LU (卢志霞) ,&nbsp;Min-xiao LIU (刘敏肖) ,&nbsp;Zhao-jie LI (李朝杰) ,&nbsp;Wei HAO (郝巍)","doi":"10.1016/j.wjam.2024.03.005","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.03.005","url":null,"abstract":"<div><p>This article reported the application of wrist-ankle acupuncture with the ultrasound-guided interfascial plane block (Transversus abdominis plane block,TAPB; Rectus sheath block, RSB; Rhomboid intercostal and sub–serratus block, RISSB) in two emergency laparotomy in elderly frail patients. These cases were successfully completed with only a small dosage of narcotic analgesics, and the patient's spontaneous breathing was preserved and the vital signs of the patients were stable with the Visual Analogue Scale (VAS) of 2 points and the oxygen saturation level over 95%. Both patients recovered soon after the surgery. The combination of wrist-ankle acupuncture and interfascial plane block to preserve spontaneous breathing during laparotomy in elderly frail patients in China had not been previously reported.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 169-173"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000151/pdfft?md5=ad30aedab550857ab6e1ba1eca4fb5e0&pid=1-s2.0-S1003525724000151-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress on acupuncture and moxibustion for treatment of Crohn's disease based on the regulation of innate immunity","authors":"Jing XIE (谢静) ,&nbsp;Wen-jia WANG (王文佳) ,&nbsp;Yu-chao HOU (侯瑜超) ,&nbsp;Ou-ping LIAO (廖欧萍) ,&nbsp;Si-wei HUANG (黄思维) ,&nbsp;Jia-jing LU (陆佳婧) ,&nbsp;Hui-rong LIU (刘慧荣) ,&nbsp;Yan HUANG (黄艳) ,&nbsp;Jing LI (李璟) ,&nbsp;Huan-gan WU (吴焕淦)","doi":"10.1016/j.wjam.2024.04.006","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.006","url":null,"abstract":"<div><p>Crohn's disease (CD) is an inflammatory bowel disease whose pathogenesis remains unclear. In this paper, we reviewed the basic research of acupuncture and moxibustion in treating CD by regulating intestinal intrinsic immunity, and summarized in more detail that acupuncture and moxibustion can regulate the intestinal intrinsic immune system through the intestinal epithelial cell barrier, monocytes/macrophages, natural killer cells (NK cells), dendritic cells (DC), and neutrophils. Specifically, acupuncture and moxibustion can reduce the expression of inflammatory factors in the intestinal mucosa, alleviate intestinal fibrosis to repair the mechanical barrier of the intestinal mucosa, inhibit the expression of molecules of the MAPK, TLR/NF-κB signaling pathway and inflammatory factors, block the NK cell-mediated cytotoxicity pathway, and prevent the overactivation of neutrophils to control inflammatory responses, repairing the damaged intestinal tract and alleviating CD symptoms. This paper illustrated the characteristics of acupuncture and moxibustion for CD, which involves multi targets and pathways, aiming to provide guidance for the clinical application and basic research of acupuncture and moxibustion for CD. It also pointed out the current drawbacks of acupuncture and moxibustion therapy, and finally proposing the shortcomings of the current research, including the insufficient number of studies on acupuncture and moxibustion in the treatment of CD through the modulation of NK cells and neutrophils, the lack of standardization in acupuncture point selection, duration and treatment course, and the geographical limitations of the research locations for acupuncture and moxibustion in treating CD.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 83-88"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000254/pdfft?md5=4f315465228fa9b5b18a44049bcf2467&pid=1-s2.0-S1003525724000254-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"China Association of Acupuncture and Moxibustion (CAAM): Leading development of acupuncture, contributing Chinese wisdom to the world","authors":"Yuan WU (吴远),&nbsp;Yin-long LI (李印泷),&nbsp;Shu-dong LI (李述东)","doi":"10.1016/j.wjam.2023.12.004","DOIUrl":"https://doi.org/10.1016/j.wjam.2023.12.004","url":null,"abstract":"","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 176-178"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525723000831/pdfft?md5=a6af277c32c7985906e2da5872eacff4&pid=1-s2.0-S1003525723000831-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupuncture regulating microglial activation in Alzheimer's disease: Research progress in its neuroinflammation mechanism","authors":"Yu-ting WEI (魏玉婷),&nbsp;Ming-li SU (苏明莉),&nbsp;De-lin REN (任德琳),&nbsp;Xin ZHANG (张鑫),&nbsp;Tian-tian ZHU (朱田田),&nbsp;Xing-ke YAN (严兴科)","doi":"10.1016/j.wjam.2024.04.004","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.004","url":null,"abstract":"<div><p>Microglia (MG) activation and its mediated neuroinflammation are closely related to the occurrence and deterioration of Alzheimer's disease (AD). Acupuncture is one of the effective approach for AD, which can relieve the symptoms and slow the deterioration of AD. Based on the role of MG activation and its induced pro-inflammatory and anti-inflammatory phenotypes in neuroinflammation, this paper reviews the related literature on the mechanism of acupuncture in regulating MG activation and relieving neuroinflammation in AD. It is found that acupuncture can inhibit abnormal MG activation by regulating the release of MG surface immune receptors and pro-inflammatory/ anti-inflammatory cytokines. It can also modulate the activity of signaling pathways associated with MG polarization, downregulate the expression of M1, and promote MG polarization towards the M2 phenotype. Additionally, it adjusts the imbalance between M1 and M2 phenotypes of MG, thereby relieving the neuroinflammatory pathological procession of and repairing the neuronal damage so as to achieve its therapeutic effect.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 89-94"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000230/pdfft?md5=0b20341a4eff8b0f893dbf40dc858a50&pid=1-s2.0-S1003525724000230-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitation with or without acupuncture for improving the knee function after total knee arthroplasty: A systematic review and meta-analysis","authors":"Wen-ming CHU (褚文明) ,&nbsp;Yuan CAO (曹原) ,&nbsp;Shi-yong LI (李世永) ,&nbsp;Qiong WU (吴琼) ,&nbsp;Xi-yan GAO (高希言)","doi":"10.1016/j.wjam.2024.04.001","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.001","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the effect and safety of acupuncture on the base of rehabilitation for knee function after total knee arthroplasty.</p></div><div><h3>Methods</h3><p>Relevant articles were collected from CNKI, Sinomed, Wanfang, VIP, Cochrane Library, Medline and Embase. The search was conducted by using a combination of subject terms and free words. The data were analyzed by Revman 5.4 software, and the included studies were evaluated in compliance with the Cochrane Collaboration's tool for assessing risk of bias in randomized trials.</p></div><div><h3>Results</h3><p>A total of 10 studies of randomized controlled trial (RCT) were included, with 785 participants involved, of which, 393 cases in experiment group and 392 cases in control group. The interventions were electroacupuncture in 4 RCTs, filiform needling in 4 RCTs and transcutaneous electrical acupoint stimulation in 2 RCTs. Meta-analysis results showed that, compared with rehabilitation alone, acupuncture combined with rehabilitation improved the score of Hospital for Special Surgery (HSS) (MD=4.27, 95% CI=[2.77, 5.78], <em>Z</em>=5.58, <em>P</em>&lt;0.00001), increased the range of motion (ROM) of the knee (MD=3.09, 95% CI=[1.47,4.70], <em>Z</em>=3.75, <em>P</em>&lt;0.001), and decreased the postoperative score of visual analogue scale (VAS) (MD=-0.53, 95%CI=[-0.74, -0.33], <em>Z</em>=5.04, <em>P</em>&lt;0.00001), but the difference in VAS score between groups only indicated statistical significance, without clinical importance. The sensitivity analysis showed the results were stable. In subgroup analysis, the stability of VAS score was relatively poorer in electroacupuncture group and filiform needle group, which may be associated with the differences in waveform of electroacupuncture and trial setting.</p></div><div><h3>Conclusion</h3><p>Compared with rehabilitation alone, acupuncture in combination with rehabilitation could effectively improve the knee function for the patients after total knee arthroplasty.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 95-102"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000205/pdfft?md5=f1506a9058f4b71ae338d7024e474cef&pid=1-s2.0-S1003525724000205-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional heterogeneity of acupoints stimulation in the modulation of autonomic nerve system","authors":"Jin-feng JIANG (姜劲峰)","doi":"10.1016/j.wjam.2024.04.002","DOIUrl":"https://doi.org/10.1016/j.wjam.2024.04.002","url":null,"abstract":"<div><p>Acupoints on the different parts of the body surface vary in regulating the autonomic nervous system (ANS), exhibiting differences in the acupoint specificity in terms of the distributing directions of sympathetic and parasympathetic branches. The paper introduces the rules of acupoints on the corresponding body surfaces in modulating ANS based on their location at four limbs, abdomen, sacrum, head and face, suboccipital and lateral cervical region and auricle (concha). The fundamental rule of acupoint heterogeneity in ANS regulation is that: all acupoints can induce somatic-sympathetic reflex. The regional heterogeneity of acupoints in ANS is shown: by the fact that stimulation beyond a certain intensity can induce systemic autonomic effects. The acupoints on the abdomen act on the sympathetic nervous system, those at concha on the vagal system and those on the sacral region on the sacral parasymathetic system. The heterogeneity of acupoints in regulating ANS refers to co-effects of acupoints specific effect (within segments) and its systemic effect (whole body), which embodies the specificity of acupoints structure. The acupoints on the same body surface regions display the homogeneity of modulation. Mastering the heterogeneous characteristics of acupoints in modulating ANS is particularly conductive to constructing the theoretical basis of acupoints in clinical acupuncture treatment for systemic diseases.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 2","pages":"Pages 77-82"},"PeriodicalIF":0.7,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000217/pdfft?md5=f61a7cb8262241a99740cf93d2e82a46&pid=1-s2.0-S1003525724000217-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141164272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on acupoints selection and combination for functional dyspepsia: Data mining of randomized controlled trials","authors":"Yu-qiao CHEN (陈宇巧),&nbsp;Jia-li WU (吴佳丽),&nbsp;Nai-xuan WEI (韦乃瑄),&nbsp;Meng-ting QIU (邱梦婷),&nbsp;Zi GUO (郭子),&nbsp;Xiao-mei SHAO (邵晓梅),&nbsp;Jiao-qiao FANG (方剑乔),&nbsp;Jun-fan FANG (房军帆),&nbsp;Jun-ying DU (杜俊英)","doi":"10.1016/j.wjam.2023.06.001","DOIUrl":"10.1016/j.wjam.2023.06.001","url":null,"abstract":"<div><h3>Background</h3><p>The aim of the study was to explore the regularity of acupoints combination in the treatment of functional dyspepsia (FD) by means of data mining technology.</p></div><div><h3>Methods</h3><p>We conducted a systematic search of nine databases from their inception to December 2022 to identify eligible randomized controlled trials (RCTs). The acupoints prescriptions in the treatment of FD were extracted and analyzed based on association rule mining and network analysis. Furthermore, the acupoints prescribed for irritability symptom of FD were quantified by forward inference, reverse inference and Bayes factor (BF) correction.</p></div><div><h3>Results</h3><p>A total of 45 RCTs on 30 acupoints were included, involving 172 times the total application frequency. Analysis of acupoints prescriptions covered 29 meridian acupoints and one extra-ordinary point, disturbing in 10 meridians. The top three acupoints in application frequency were Zusanli (ST36, 19.77%), Neiguan (PC6, 16.86%), Zhongwan (CV12, 12.21%). The most involved meridian was the foot <em>yangming</em> stomach meridian (34 times). The most frequently used acupoints combinations were PC6 and ST36. The core prescriptions were ST36, PC6, Tianshu(ST25), CV12. The specificities of acupoints selection for FD with dysphoria as follows: using the forward inference, PC6, Taichong(LR3), Qimen(LR14), CV12, Danzhong(CV17), ST25, ST36 were selected. Using the reverse inference and BF correction, PC6, CV12, CV17, Sanyinjiao(SP6), ST25, ST36 were selected.</p></div><div><h3>Conclusion</h3><p>ST36, PC6, ST25, CV12 could be used as the main prescriptions in treating FD. For FD with dysphoria the acupoints prescription is PC6, CV12, CV17, ST25 and ST36.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 1","pages":"Pages 40-53"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525723000417/pdfft?md5=9702e21f4cbebad2e714f92e384e80dd&pid=1-s2.0-S1003525723000417-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48382207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}